RO70295A - PREPARATION OF THE ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXY-CARBONYL-4- (2'-NITROFENYL) -1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID - Google Patents

PREPARATION OF THE ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXY-CARBONYL-4- (2'-NITROFENYL) -1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID

Info

Publication number: RO70295A
Authority: RO; Romania
Prior art keywords: nitrofenyl; dihydropyridine; carbonyl; methoxy; dimethyl
Prior art date: 1975-11-05

Application number

RO7688294A

Other languages

French (fr)

Romanian (ro)

Inventor

Egbert Wehinger

Friedrich Bossert

Arend Heise

Stanislav Kazda

Kurt Stoepel

Wulf Vater

Original Assignee

Bayer Ag,De

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-11-05

Filing date

1976-11-02

Publication date

1981-08-17

1976-11-02 Application filed by Bayer Ag,De filed Critical Bayer Ag,De

1981-08-17 Publication of RO70295A publication Critical patent/RO70295A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

RO7688294A 1975-11-05 1976-11-02 PREPARATION OF THE ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXY-CARBONYL-4- (2'-NITROFENYL) -1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID RO70295A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2549568A DE2549568C3 (en)	1975-11-05	1975-11-05	2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl) -1,4-dihydropyridine-5-carboxylic acid isobutyl ester, several processes for its preparation and pharmaceuticals containing it

Publications (1)

Publication Number	Publication Date
RO70295A true RO70295A (en)	1981-08-17

Family

ID=5960951

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RO7688294A RO70295A (en)	1975-11-05	1976-11-02	PREPARATION OF THE ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXY-CARBONYL-4- (2'-NITROFENYL) -1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID

Country Status (27)

Country	Link
JP (1)	JPS5259161A (en)
AT (1)	AT352129B (en)
AU (1)	AU498964B2 (en)
BE (1)	BE847968A (en)
BG (6)	BG24804A3 (en)
CA (1)	CA1085406A (en)
CH (2)	CH623038A5 (en)
CS (1)	CS200499B2 (en)
DE (1)	DE2549568C3 (en)
DK (1)	DK146762C (en)
ES (2)	ES452986A1 (en)
FI (1)	FI60704C (en)
FR (1)	FR2330395A1 (en)
GB (1)	GB1516793A (en)
GR (1)	GR61241B (en)
HK (1)	HK12681A (en)
IE (1)	IE43984B1 (en)
IL (1)	IL50817A (en)
LU (2)	LU88275I2 (en)
NL (2)	NL175915C (en)
NO (1)	NO145574C (en)
NZ (1)	NZ182502A (en)
PL (2)	PL106084B1 (en)
PT (1)	PT65797B (en)
RO (1)	RO70295A (en)
SE (1)	SE423542B (en)
ZA (1)	ZA766622B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146630A (en) *	1976-11-12	1979-03-27	Boehringer Mannheim Gmbh	Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) *	1978-02-14	1980-01-05	Yamanouchi Pharmaceut Co Ltd	1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (en) *	1982-04-06	1983-10-13	Bayer Ag, 5090 Leverkusen	USE OF DIHYDROPYRIDINES IN MEDICINAL PRODUCTS WITH SALIDIURETIC EFFECT
DE3222367A1 (en) *	1982-06-15	1983-12-15	Bayer Ag, 5090 Leverkusen	Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
JPS5982192U (en) *	1982-11-27	1984-06-02	エムケ−精工株式会社	door
DE3312216A1 (en) *	1983-04-05	1984-10-11	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING SYMMETRIC 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
DE3312283A1 (en) *	1983-04-05	1984-10-18	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING UNBALANCED 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
US4794111A (en) *	1984-05-23	1988-12-27	Bayer Aktiengesellschaft	Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2117571C3 (en) *	1971-04-10	1979-10-11	Bayer Ag, 5090 Leverkusen	Asymmetrical 1,4-dihydropyridine-33-dicarboxylic acid esters, process for their preparation and their use as pharmaceuticals

1975
- 1975-11-05 DE DE2549568A patent/DE2549568C3/en not_active Expired
1976
- 1976-10-22 NO NO763608A patent/NO145574C/en unknown
- 1976-10-29 JP JP51129540A patent/JPS5259161A/en active Granted
- 1976-11-01 BG BG035344A patent/BG24804A3/en unknown
- 1976-11-01 BG BG035341A patent/BG25078A3/en unknown
- 1976-11-01 BG BG034575A patent/BG24668A3/en unknown
- 1976-11-01 BG BG035342A patent/BG25079A3/en unknown
- 1976-11-01 BG BG035345A patent/BG24805A3/en unknown
- 1976-11-01 BG BG035343A patent/BG24803A3/en unknown
- 1976-11-02 CS CS767068A patent/CS200499B2/en unknown
- 1976-11-02 NZ NZ182502A patent/NZ182502A/en unknown
- 1976-11-02 GB GB45501/76A patent/GB1516793A/en not_active Expired
- 1976-11-02 RO RO7688294A patent/RO70295A/en unknown
- 1976-11-02 IL IL50817A patent/IL50817A/en unknown
- 1976-11-02 CH CH1381976A patent/CH623038A5/en not_active IP Right Cessation
- 1976-11-03 AT AT814276A patent/AT352129B/en not_active IP Right Cessation
- 1976-11-03 NL NLAANVRAGE7612198,A patent/NL175915C/en not_active IP Right Cessation
- 1976-11-03 PL PL1976193438A patent/PL106084B1/en unknown
- 1976-11-03 FI FI763160A patent/FI60704C/en not_active IP Right Cessation
- 1976-11-03 PL PL1976201800A patent/PL105940B1/en unknown
- 1976-11-04 BE BE172063A patent/BE847968A/en not_active IP Right Cessation
- 1976-11-04 PT PT65797A patent/PT65797B/en unknown
- 1976-11-04 ES ES452986A patent/ES452986A1/en not_active Expired
- 1976-11-04 DK DK498476A patent/DK146762C/en not_active IP Right Cessation
- 1976-11-04 LU LU88275C patent/LU88275I2/xx unknown
- 1976-11-04 LU LU76133A patent/LU76133A1/xx active Protection Beyond IP Right Term
- 1976-11-04 CA CA264,921A patent/CA1085406A/en not_active Expired
- 1976-11-04 GR GR52093A patent/GR61241B/en unknown
- 1976-11-04 ZA ZA766622A patent/ZA766622B/en unknown
- 1976-11-04 SE SE7612308A patent/SE423542B/en not_active IP Right Cessation
- 1976-11-04 IE IE2458/76A patent/IE43984B1/en not_active IP Right Cessation
- 1976-11-05 AU AU19358/76A patent/AU498964B2/en not_active Expired
- 1976-11-05 FR FR7633488A patent/FR2330395A1/en active Granted
1977
- 1977-10-13 ES ES463166A patent/ES463166A1/en not_active Expired
1980
- 1980-07-23 CH CH567880A patent/CH622779A5/en not_active IP Right Cessation
1981
- 1981-04-02 HK HK126/81A patent/HK12681A/en unknown
1993
- 1993-05-24 NL NL930035C patent/NL930035I2/en unknown

Also Published As

Publication number	Publication date
BE847968A (en)	1977-05-04
DE2549568C3 (en)	1981-10-29
ZA766622B (en)	1977-10-26
FI60704C (en)	1982-03-10
FI60704B (en)	1981-11-30
LU88275I2 (en)	1994-02-03
IE43984B1 (en)	1981-07-15
AU498964B2 (en)	1979-03-29
BG25079A3 (en)	1978-07-12
BG24668A3 (en)	1978-04-12
GB1516793A (en)	1978-07-05
FR2330395B1 (en)	1978-12-22
IE43984L (en)	1977-05-05
CH623038A5 (en)	1981-05-15
ES463166A1 (en)	1978-07-16
PL106084B1 (en)	1979-11-30
PL105940B1 (en)	1979-11-30
FI763160A (en)	1977-05-06
DK146762C (en)	1984-06-12
DK498476A (en)	1977-05-06
NO763608L (en)	1977-05-06
NL930035I1 (en)	1993-08-02
NL175915C (en)	1985-01-16
NO145574B (en)	1982-01-11
BG24804A3 (en)	1978-05-12
BG25078A3 (en)	1978-07-12
NO145574C (en)	1982-04-21
ATA814276A (en)	1979-02-15
SE7612308L (en)	1977-05-06
SE423542B (en)	1982-05-10
CH622779A5 (en)	1981-04-30
HK12681A (en)	1981-04-10
AT352129B (en)	1979-09-10
CS200499B2 (en)	1980-09-15
LU76133A1 (en)	1977-06-02
JPS5647185B2 (en)	1981-11-07
DE2549568B2 (en)	1980-08-21
CA1085406A (en)	1980-09-09
BG24805A3 (en)	1978-05-12
DE2549568A1 (en)	1977-05-18
IL50817A0 (en)	1977-01-31
PT65797A (en)	1976-12-01
PT65797B (en)	1978-05-12
NL7612198A (en)	1977-05-09
NZ182502A (en)	1978-07-28
AU1935876A (en)	1978-05-11
FR2330395A1 (en)	1977-06-03
BG24803A3 (en)	1978-05-12
ES452986A1 (en)	1977-12-16
JPS5259161A (en)	1977-05-16
DK146762B (en)	1983-12-27
IL50817A (en)	1979-07-25
NL930035I2 (en)	1993-10-01
GR61241B (en)	1978-10-12

Publication	Publication Date	Title
TR19755A (en)	1979-11-28	PROCEDURE FOR THE PREPARATION OF TEROPHTHALIC ACID
SE7801428L (en)	1978-08-09	PROCEDURE FOR THE PREPARATION OF CEFEMCARBONIC ACIDS
NO771578L (en)	1978-09-18	PROCEDURE FOR THE PREPARATION OF DI-N-PROPYLATIC ACID
BE843964A (en)	1977-01-10	IMPROVEMENTS RELATED TO THE EXTRACTION OF GELATINE
RO70295A (en)	1981-08-17	PREPARATION OF THE ISOBUTYL ESTER OF 2,6-DIMETHYL-3-METHOXY-CARBONYL-4- (2'-NITROFENYL) -1,4-DIHYDROPYRIDINE-5-CARBOXYLIC ACID
RO77485A (en)	1981-11-04	PROCEDURE FOR THE PREPARATION OF 1,2,3-TIADIAZOL-3-IN-5-ILIDENDURES
RO70629A (en)	1981-01-30	PROCEDURE FOR THE PREPARATION OF 3,4-DIHYDRO-2-METHYL-4-OXO-2H-1,2-BENZOTIAZINE-3-CARBOXYLIC ACID 1,1-DIOXIDE
SE7804878L (en)	1978-10-29	PROCEDURE FOR THE PREPARATION OF 1,2-DICHLORETANE
SE7601605L (en)	1976-08-30	PROCEDURE FOR THE PREPARATION OF 1 ALFA, 25-DIHYDROXY-CHOLCALCIFEROL
RO77345A (en)	1981-08-17	PROCESS FOR THE PREPARATION OF 4 "-DESOXY-4" -AMINOERYTHROMYCIN A DESRIVES
FR2314732A1 (en)	1977-01-14	IODOPHORE SOLUTION
NO774503L (en)	1978-07-03	PROCEDURE FOR THE PREPARATION OF OCTAHYDRO-INDOLO (2,3, A) -CHINOLIZINES
BE839258A (en)	1976-09-06	IMPROVEMENTS IN THE PREPARATION OF ALLOYS
IL49486A0 (en)	1976-06-30	The preparation of perpropionic acid solutions
IL49485A0 (en)	1976-06-30	The preparation of perpropionic acid solutions
AR210905A1 (en)	1977-09-30	PROCEDURE FOR THE PREPARATION OF 2,4-DIAMINE-5-BENZYL-PYRIMIDINES
FR2328511A1 (en)	1977-05-20	PREPARATION OF AMMONOXIDATION CATALYSTS
FR2332254A1 (en)	1977-06-17	PREPARATION OF A HYDROXY-ALDEHYDE
IL53550A0 (en)	1978-03-10	The preparation of o,o-dialkyl-s-(n-methyl-carboxamidomethyl)-thiol-phosphoric acid esters
AR211237A1 (en)	1977-11-15	A PROCEDURE FOR THE PREPARATION OF N- (1'-ALYLPYRROLIDINYL-2'-MENTIL) 2-METHOXY-4,5-AZIMIDOBENZAMIDE
FR2322843A1 (en)	1977-04-01	PREPARATION OF 6, 10, 14-TRIMETHYLPENTADECA-2-ONE
NZ184432A (en)	1978-09-25	Preparation of 3,3-dimethylpent-4-endic acid
GB1554058A (en)	1979-10-17	Preparation of 3,5-dialkyl-4-hydroxybenzoic acid
AR212814A1 (en)	1978-10-13	PROCEDURE FOR THE PREPARATION OF N-2'-CARBOXIFENIL-4-CHLOROANTRANILICO ACID DERIVATIVES
AR211532A1 (en)	1978-01-30	A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF THENOPYRIDINE