PT92515A - Processo para a preparacao de novos derivados imidazolicos substituidos - Google Patents

Processo para a preparacao de novos derivados imidazolicos substituidos

Info

Publication number: PT92515A
Authority: PT; Portugal
Prior art keywords: substituted; preparing new; hal; alkyl; imidazolic
Prior art date: 1988-12-09

Application number

PT92515A

Other languages

English (en)

Other versions

PT92515B (pt

Inventor

Arto Johannes Karjalainen

Arja Leena Karjalainen

Raimo Einari Virtanen

Original Assignee

Farmos Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-09

Filing date

1989-12-07

Publication date

1990-06-29

1989-12-07 Application filed by Farmos Oy filed Critical Farmos Oy

1990-06-29 Publication of PT92515A publication Critical patent/PT92515A/pt

1995-08-09 Publication of PT92515B publication Critical patent/PT92515B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Diabetes (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PT92515A 1988-12-09 1989-12-07 Processo para a preparacao de novos derivados imidazolicos substituidos PT92515B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8828831A GB2225782A (en)	1988-12-09	1988-12-09	Imidazole derivatives useful for treatment of diabetes

Publications (2)

Publication Number	Publication Date
PT92515A true PT92515A (pt)	1990-06-29
PT92515B PT92515B (pt)	1995-08-09

Family

ID=10648267

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT92515A PT92515B (pt)	1988-12-09	1989-12-07	Processo para a preparacao de novos derivados imidazolicos substituidos

Country Status (22)

Country	Link
US (1)	US5292887A (pt)
EP (1)	EP0372954B1 (pt)
JP (1)	JP2868813B2 (pt)
KR (1)	KR900009605A (pt)
CN (1)	CN1023219C (pt)
AT (1)	ATE102608T1 (pt)
AU (1)	AU619928B2 (pt)
CA (1)	CA2004799A1 (pt)
DD (1)	DD290880A5 (pt)
DE (1)	DE68913673T2 (pt)
DK (1)	DK603789A (pt)
ES (1)	ES2052937T3 (pt)
FI (1)	FI96026C (pt)
GB (1)	GB2225782A (pt)
HU (1)	HU205086B (pt)
IE (1)	IE61870B1 (pt)
IL (1)	IL92609A0 (pt)
NO (1)	NO177138C (pt)
NZ (1)	NZ231649A (pt)
PT (1)	PT92515B (pt)
RU (2)	RU1831479C (pt)
ZA (1)	ZA899366B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI862039A0 (fi) *	1986-05-15	1986-05-15	Farmos Oy	Nytt foerfarande foer framstaellning av 4(5)-substituerade imidazolderivat.
GB9127050D0 (en) *	1991-12-20	1992-02-19	Orion Yhtymae Oy	Substituted imidazole derivatives and their preparation and use
GB9312669D0 (en)	1993-06-18	1993-08-04	Orion Yhtymae Oy	New opticla isomers
FR2735776B1 (fr) *	1995-06-22	1997-07-18	Synthelabo	Derives de 2,3-dihydro-1h-indole, leur preparation et leur application en therapeutique
EP1147092A1 (en) *	1999-01-18	2001-10-24	Novo Nordisk A/S	Substituted imidazoles, their preparation and use
US6388090B2 (en)	2000-01-14	2002-05-14	Orion Corporation	Imidazole derivatives
FI20000073A0 (fi) *	2000-01-14	2000-01-14	Orion Yhtymae Oy	Uusia imidatsolijohdannaisia
WO2001085698A1 (en)	2000-05-08	2001-11-15	Orion Corporation	New polycyclic indanylimidazoles with alpha2 adrenergic activity
FR2839719B1 (fr) *	2002-05-16	2004-08-06	Pf Medicament	Nouveaux composes imidazoliques, leur procede de preparation et leur utilisation a titre de medicaments
US8188126B2 (en)	2002-05-16	2012-05-29	Pierre Fabre Medicament	Imidazolic compounds and use thereof as alpha-2 adrenergic receptors
GB0226076D0 (en) *	2002-11-08	2002-12-18	Rp Scherer Technologies Inc	Improved formulations containing substituted imidazole derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2167408B (en) *	1984-11-23	1988-05-25	Farmos Oy	Substituted imidazole derivatives and their preparation and use
FI81092C (fi) *	1986-05-15	1990-09-10	Farmos Oy	Foerfarande foer framstaellning av terapeutiskt aktiva 4(5)-(2,3-dihydro-1h-inden-2-yl)-imidazolderivat.

1988
- 1988-12-09 GB GB8828831A patent/GB2225782A/en not_active Withdrawn
1989
- 1989-11-09 FI FI895325A patent/FI96026C/fi not_active IP Right Cessation
- 1989-11-16 NO NO894563A patent/NO177138C/no not_active IP Right Cessation
- 1989-11-30 DK DK603789A patent/DK603789A/da not_active Application Discontinuation
- 1989-12-06 AU AU45992/89A patent/AU619928B2/en not_active Ceased
- 1989-12-06 US US07/446,839 patent/US5292887A/en not_active Expired - Fee Related
- 1989-12-06 NZ NZ231649A patent/NZ231649A/xx unknown
- 1989-12-06 CA CA002004799A patent/CA2004799A1/en not_active Abandoned
- 1989-12-07 KR KR1019890018116A patent/KR900009605A/ko not_active Application Discontinuation
- 1989-12-07 PT PT92515A patent/PT92515B/pt not_active IP Right Cessation
- 1989-12-07 IE IE392689A patent/IE61870B1/en not_active IP Right Cessation
- 1989-12-07 DD DD89335371A patent/DD290880A5/de not_active IP Right Cessation
- 1989-12-07 ZA ZA899366A patent/ZA899366B/xx unknown
- 1989-12-07 ES ES89312755T patent/ES2052937T3/es not_active Expired - Lifetime
- 1989-12-07 EP EP89312755A patent/EP0372954B1/en not_active Expired - Lifetime
- 1989-12-07 AT AT89312755T patent/ATE102608T1/de not_active IP Right Cessation
- 1989-12-07 DE DE68913673T patent/DE68913673T2/de not_active Expired - Fee Related
- 1989-12-08 RU SU4742612A patent/RU1831479C/ru active
- 1989-12-08 CN CN89109220A patent/CN1023219C/zh not_active Expired - Fee Related
- 1989-12-08 IL IL92609A patent/IL92609A0/xx unknown
- 1989-12-08 JP JP1320387A patent/JP2868813B2/ja not_active Expired - Fee Related
- 1989-12-08 HU HU896481A patent/HU205086B/hu not_active IP Right Cessation
1991
- 1991-01-08 RU SU91A patent/RU1833375C/ru active

Also Published As

Publication number	Publication date
CN1023219C (zh)	1993-12-22
NO894563D0 (no)	1989-11-16
AU619928B2 (en)	1992-02-06
HU205086B (en)	1992-03-30
NZ231649A (en)	1991-09-25
ATE102608T1 (de)	1994-03-15
GB8828831D0 (en)	1989-01-18
IE61870B1 (en)	1994-11-30
JP2868813B2 (ja)	1999-03-10
GB2225782A (en)	1990-06-13
FI96026C (fi)	1996-04-25
DK603789D0 (da)	1989-11-30
IE893926L (en)	1990-06-09
NO177138B (no)	1995-04-18
CA2004799A1 (en)	1990-06-09
DD290880A5 (de)	1991-06-13
US5292887A (en)	1994-03-08
DE68913673T2 (de)	1994-07-14
DE68913673D1 (de)	1994-04-14
EP0372954B1 (en)	1994-03-09
RU1831479C (ru)	1993-07-30
FI895325A0 (fi)	1989-11-09
FI96026B (fi)	1996-01-15
ZA899366B (en)	1991-03-27
RU1833375C (en)	1993-08-07
ES2052937T3 (es)	1994-07-16
JPH02202874A (ja)	1990-08-10
CN1043128A (zh)	1990-06-20
HUT52065A (en)	1990-06-28
PT92515B (pt)	1995-08-09
IL92609A0 (en)	1990-08-31
NO894563L (no)	1990-06-11
KR900009605A (ko)	1990-07-05
DK603789A (da)	1990-06-10
EP0372954A1 (en)	1990-06-13
AU4599289A (en)	1990-08-16
NO177138C (no)	1995-07-26

Publication	Publication Date	Title
ATE85050T1 (de)	1993-02-15	Substituierte imidazol-derivate und verfahren zu deren herstellung und deren anwendung.
PT92515A (pt)	1990-06-29	Processo para a preparacao de novos derivados imidazolicos substituidos
YU45423B (en)	1992-05-28	Process for obtaining heterocyclical benzene derivatives
ES2046229T3 (es)	1994-02-01	Composicion antiulcerosa.
ATE137759T1 (de)	1996-05-15	S'-adenosyl-methionin-decarboxylase-inhibitoren
PT78717B (de)	1986-10-21	Neue 1-acetonyl-2-(phenylimino)-imidazolidine deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
ATE138376T1 (de)	1996-06-15	Verfahren zur herstellung von benzylphthalazinonderivaten und von deren salzen
ATE241594T1 (de)	2003-06-15	N-phenylacetoacetamide und verfahren zu ihrer herstellung
PT82550B (pt)	1988-08-17	Processo de preparacao de derivados de 1,3-oxatiano e de composicoes farmaceuticas que os contem
ATE39354T1 (de)	1989-01-15	Monosilylierte aminophenylethylamin-derivate, verfahren zu ihrer herstellung und ihre verwendung zur wachstumsfoerderung.
KR890003690A (ko)	1989-04-17	우레아 유도체
ZA812541B (en)	1982-12-29	Benzothiazole derivatives and salts thereof,processes for their preparation,and their use as sweetening agents
PT87954A (pt)	1989-06-30	Processo para a preparacao de composicoes farmaceuticas contendo derivados de dioxopiperidina, com efeito antipsicotico
ATE33493T1 (de)	1988-04-15	Phenylethylaminopropiophenon-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ES2031850T3 (es)	1993-01-01	Procedimiento para la obtencion de derivados de transbenzopiran-(4,3-b)-1,4-oxazina.
ES2040223T3 (es)	1993-10-16	Derivados de la tiadiazolilacetamida, procedimiento para su fabricacion y su utilizacion.
DK561389A (da)	1990-05-11	Hukommelsesforbedrende midler indeholdende dioxopiperidinderivater

Legal Events

Date	Code	Title	Description
1995-08-09	FG3A	Patent granted, date of granting	Effective date: 19950404
2004-12-31	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20041004

Date

Code

Title

Description

1995-08-09

FG3A

Patent granted, date of granting

Effective date: 19950404

2004-12-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20041004