PT91525A - Processo de preparacao de composicoes farmaceuticas a base de derivados do acido fosfinico - Google Patents
Processo de preparacao de composicoes farmaceuticas a base de derivados do acido fosfinicoInfo
- Publication number
- PT91525A PT91525A PT91525A PT9152589A PT91525A PT 91525 A PT91525 A PT 91525A PT 91525 A PT91525 A PT 91525A PT 9152589 A PT9152589 A PT 9152589A PT 91525 A PT91525 A PT 91525A
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical compositions
- phosphinic acid
- acid derivatives
- compositions based
- preparing pharmaceutical
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- ACVYVLVWPXVTIT-UHFFFAOYSA-N phosphinic acid Chemical class O[PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-N 0.000 title 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- BCDIWLCKOCHCIH-UHFFFAOYSA-N methylphosphinic acid Chemical compound CP(O)=O BCDIWLCKOCHCIH-UHFFFAOYSA-N 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5537—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888820266A GB8820266D0 (en) | 1988-08-26 | 1988-08-26 | Compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
PT91525A true PT91525A (pt) | 1990-03-08 |
PT91525B PT91525B (pt) | 1995-05-04 |
Family
ID=10642740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT91525A PT91525B (pt) | 1988-08-26 | 1989-08-23 | Processo de preparacao de composicoes farmaceuticas a base de derivados do acido fosfinico |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0356128B1 (pt) |
JP (1) | JPH03502101A (pt) |
AT (1) | ATE77747T1 (pt) |
AU (1) | AU614668B2 (pt) |
DE (1) | DE68901961T2 (pt) |
DK (1) | DK101990A (pt) |
ES (1) | ES2043025T3 (pt) |
GB (1) | GB8820266D0 (pt) |
GR (1) | GR3005094T3 (pt) |
IE (1) | IE892738L (pt) |
PT (1) | PT91525B (pt) |
WO (1) | WO1990001936A1 (pt) |
ZA (1) | ZA896504B (pt) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5243062A (en) * | 1984-10-12 | 1993-09-07 | Ciba-Geigy Corporation | Substituted propane-phosphonous acid compounds |
US5457095A (en) * | 1984-10-12 | 1995-10-10 | Ciba-Geigy Corporation | Substituted propane-phosponous acid compounds |
US5300679A (en) * | 1987-12-04 | 1994-04-05 | Ciba-Geigy Corporation | Substituted propane-phosphinic acid compounds |
GB8728483D0 (en) * | 1987-12-04 | 1988-01-13 | Ciba Geigy Ag | Chemical compounds |
US5190933A (en) * | 1987-12-04 | 1993-03-02 | Ciba-Geigy Corporation | Substituted propane-phosphinic acid compounds |
US5567840A (en) * | 1989-05-13 | 1996-10-22 | Ciba-Geigy Corporation | Substituted aminoalkylphosphinic acids |
GB8911017D0 (en) * | 1989-05-13 | 1989-06-28 | Ciba Geigy Ag | Substituted aminoalkylphosphinic acids |
US5281747A (en) * | 1989-05-13 | 1994-01-25 | Ciba-Geigy Corporation | Substituted aminoalkylphosphinic acids |
US5190934A (en) * | 1989-06-03 | 1993-03-02 | Ciba-Geigy Corporation | P-subsituted propane-phosphinic acid compounds |
GB8912814D0 (en) * | 1989-06-03 | 1989-07-19 | Ciba Geigy Ag | P-substituted propane-phospinic acid compounds |
IL114631A (en) * | 1990-06-22 | 1998-12-06 | Novartis Ag | Anti-epileptic preparations containing antagonists of BABAG |
EP0543780A3 (en) * | 1991-11-21 | 1993-09-01 | Ciba-Geigy Ag | Novel aminoalkanephosphinic acids and their salts |
AU662404B2 (en) * | 1992-05-08 | 1995-08-31 | Novartis Ag | Novel N-aralkyl- and N-heteroaralkyl-aminoalkanephosphinic acids |
GB9308430D0 (en) * | 1993-04-23 | 1993-06-09 | Glaxo Group Ltd | Medicaments |
SE9904507D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
SE9904508D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
US7319095B2 (en) | 1999-12-09 | 2008-01-15 | Astrazeneca Ab | Use of GABAB receptor agonists |
AR033779A1 (es) | 2001-06-08 | 2004-01-07 | Astrazeneca Ab | Compuestos utiles en la enfermedad de reflujo |
DK1691811T3 (da) | 2003-12-11 | 2014-10-20 | Sunovion Pharmaceuticals Inc | Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression |
SE0401653D0 (sv) | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | New compounds |
US7678363B2 (en) | 2005-08-26 | 2010-03-16 | Braincells Inc | Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
WO2007047978A2 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
WO2007073298A1 (en) | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Imidazole derivatives for the treatment of gastrointestinal disorders |
WO2007073300A1 (en) | 2005-12-23 | 2007-06-28 | Astrazeneca Ab | Gaba-b receptor modulators |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
CA2651813A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
AU2007249435A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
WO2011113904A1 (en) | 2010-03-17 | 2011-09-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Medicaments for the prevention and treatment of a disease associated with retinal ganglion cell degeneration |
US9089531B2 (en) | 2010-09-28 | 2015-07-28 | The Regents Of The University Of California | GABA agonists in the treatment of disorders associated with metabolic syndrome and GABA combinations in treatment or prophylaxis of type I diabetes |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2032712C3 (de) * | 1970-07-02 | 1978-10-19 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von w-Amino-alkanphosphonsäure bzw.- phosphinsäurederivaten |
GB8425872D0 (en) * | 1984-10-12 | 1984-11-21 | Ciba Geigy Ag | Chemical compounds |
-
1988
- 1988-08-26 GB GB888820266A patent/GB8820266D0/en active Pending
-
1989
- 1989-08-16 AT AT89308311T patent/ATE77747T1/de not_active IP Right Cessation
- 1989-08-16 ES ES89308311T patent/ES2043025T3/es not_active Expired - Lifetime
- 1989-08-16 DE DE8989308311T patent/DE68901961T2/de not_active Expired - Lifetime
- 1989-08-16 EP EP89308311A patent/EP0356128B1/en not_active Expired - Lifetime
- 1989-08-23 WO PCT/GB1989/000981 patent/WO1990001936A1/en unknown
- 1989-08-23 AU AU42043/89A patent/AU614668B2/en not_active Ceased
- 1989-08-23 PT PT91525A patent/PT91525B/pt not_active IP Right Cessation
- 1989-08-23 JP JP1509477A patent/JPH03502101A/ja active Pending
- 1989-08-25 IE IE892738A patent/IE892738L/xx unknown
- 1989-08-25 ZA ZA896504A patent/ZA896504B/xx unknown
-
1990
- 1990-04-25 DK DK101990A patent/DK101990A/da not_active Application Discontinuation
-
1992
- 1992-07-02 GR GR920401249T patent/GR3005094T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2043025T3 (es) | 1993-12-16 |
EP0356128A3 (en) | 1990-06-13 |
DK101990D0 (da) | 1990-04-25 |
WO1990001936A1 (en) | 1990-03-08 |
GB8820266D0 (en) | 1988-09-28 |
DK101990A (da) | 1990-04-25 |
AU4204389A (en) | 1990-03-23 |
IE892738L (en) | 1990-02-26 |
DE68901961T2 (de) | 1992-12-24 |
JPH03502101A (ja) | 1991-05-16 |
GR3005094T3 (pt) | 1993-05-24 |
EP0356128A2 (en) | 1990-02-28 |
ATE77747T1 (de) | 1992-07-15 |
PT91525B (pt) | 1995-05-04 |
AU614668B2 (en) | 1991-09-05 |
EP0356128B1 (en) | 1992-07-01 |
DE68901961D1 (en) | 1992-08-06 |
ZA896504B (en) | 1992-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19941013 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960430 |