PT90308A - Processo para a preparacao de composicoes farmaceuticas contendo azelastina com libertacao controlada da substancia activa - Google Patents
Processo para a preparacao de composicoes farmaceuticas contendo azelastina com libertacao controlada da substancia activaInfo
- Publication number
- PT90308A PT90308A PT90308A PT9030889A PT90308A PT 90308 A PT90308 A PT 90308A PT 90308 A PT90308 A PT 90308A PT 9030889 A PT9030889 A PT 9030889A PT 90308 A PT90308 A PT 90308A
- Authority
- PT
- Portugal
- Prior art keywords
- pharmaceutical compositions
- active substance
- controlled
- libertacaous
- azelastin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Rotary Pumps (AREA)
- Switches With Compound Operations (AREA)
- Polyurethanes Or Polyureas (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3813244 | 1988-04-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT90308A true PT90308A (pt) | 1989-11-10 |
PT90308B PT90308B (pt) | 1994-10-31 |
Family
ID=6352451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT90308A PT90308B (pt) | 1988-04-20 | 1989-04-19 | Processo para a preparacao de composicoes farmaceuticas contendo azelastina com libertacao controlada da substancia activa |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0338444B1 (pt) |
JP (1) | JP2950845B2 (pt) |
AT (1) | ATE97572T1 (pt) |
AU (1) | AU3318389A (pt) |
CA (1) | CA1325976C (pt) |
DE (1) | DE58906232D1 (pt) |
DK (1) | DK172235B1 (pt) |
ES (1) | ES2060685T3 (pt) |
FI (1) | FI891865A (pt) |
HK (1) | HK134494A (pt) |
HU (1) | HU202403B (pt) |
IE (1) | IE62778B1 (pt) |
MC (1) | MC2025A1 (pt) |
PT (1) | PT90308B (pt) |
ZA (1) | ZA892877B (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9003903D0 (sv) * | 1990-12-07 | 1990-12-07 | Astra Ab | New pharmaceutical formulations |
DE4207234A1 (de) * | 1992-03-07 | 1993-09-09 | Asta Medica Ag | Neue aminocarbonsaeure-derivate mit antiallergischer/antiasthmatischer wirkung und verfahren zu deren herstellung |
JPH0710747A (ja) * | 1993-04-28 | 1995-01-13 | Takeda Chem Ind Ltd | 固形製剤およびその製造方法 |
GB9514842D0 (en) * | 1995-07-20 | 1995-09-20 | Smithkline Beecham Plc | Novel formulation |
JP4138910B2 (ja) | 1997-07-02 | 2008-08-27 | 帝國製薬株式会社 | 経皮吸収性が良好で且つ皮膚刺激性の少ない塩酸アゼラスチン含有経皮製剤 |
UA67802C2 (uk) * | 1998-10-23 | 2004-07-15 | Пфайзер Рісьоч Енд Дівелепмент Компані, Н.В./С.А. | Фармацевтична композиція з контрольованим вивільненням інгібітора цгмф фде-5 (варіанти), спосіб її одержання та спосіб лікування еректильної дисфункції |
EP1126826B3 (en) | 1998-11-02 | 2019-05-15 | Alkermes Pharma Ireland Limited | Multiparticulate modified release composition of methylphenidate |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
EP2295043A1 (en) | 1999-10-29 | 2011-03-16 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
CN100518827C (zh) | 2000-10-30 | 2009-07-29 | 欧罗赛铁克股份有限公司 | 控释氢可酮制剂 |
EP1396263A1 (en) * | 2002-08-09 | 2004-03-10 | Warner-Lambert Company | Film coating for tablets and caplets |
CA2510319A1 (en) * | 2002-12-20 | 2004-07-15 | Thomas J. Smith | High pressure compaction for pharmaceutical formulations |
PL2486942T3 (pl) * | 2004-11-24 | 2019-05-31 | Meda Pharmaceuticals Inc | Kompozycje zawierające azelastynę oraz sposoby ich stosowania |
WO2014153541A1 (en) | 2013-03-21 | 2014-09-25 | Eupraxia Pharmaceuticals USA LLC | Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith |
JP2018531951A (ja) | 2015-10-27 | 2018-11-01 | ユープラシア ファーマシューティカルズ インク. | 局所麻酔薬の徐放性製剤 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0174464B1 (de) * | 1984-09-14 | 1990-01-03 | ASTA Pharma AG | Substituierte Benzylphthalazinon-Derivate |
-
1989
- 1989-04-11 MC MC892044A patent/MC2025A1/xx unknown
- 1989-04-14 AT AT89106685T patent/ATE97572T1/de not_active IP Right Cessation
- 1989-04-14 ES ES89106685T patent/ES2060685T3/es not_active Expired - Lifetime
- 1989-04-14 EP EP89106685A patent/EP0338444B1/de not_active Expired - Lifetime
- 1989-04-14 DE DE89106685T patent/DE58906232D1/de not_active Expired - Lifetime
- 1989-04-19 HU HU891912A patent/HU202403B/hu not_active IP Right Cessation
- 1989-04-19 AU AU33183/89A patent/AU3318389A/en not_active Abandoned
- 1989-04-19 IE IE126389A patent/IE62778B1/en not_active IP Right Cessation
- 1989-04-19 DK DK189189A patent/DK172235B1/da not_active IP Right Cessation
- 1989-04-19 ZA ZA892877A patent/ZA892877B/xx unknown
- 1989-04-19 PT PT90308A patent/PT90308B/pt not_active IP Right Cessation
- 1989-04-19 FI FI891865A patent/FI891865A/fi not_active Application Discontinuation
- 1989-04-19 CA CA000597169A patent/CA1325976C/en not_active Expired - Lifetime
- 1989-04-20 JP JP1099031A patent/JP2950845B2/ja not_active Expired - Lifetime
-
1994
- 1994-12-01 HK HK134494A patent/HK134494A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IE891263L (en) | 1989-10-20 |
HUT49808A (en) | 1989-11-28 |
HK134494A (en) | 1994-12-09 |
EP0338444A1 (de) | 1989-10-25 |
CA1325976C (en) | 1994-01-11 |
DK189189D0 (da) | 1989-04-19 |
HU202403B (en) | 1991-03-28 |
ATE97572T1 (de) | 1993-12-15 |
DE58906232D1 (de) | 1994-01-05 |
FI891865A (fi) | 1989-10-21 |
DK172235B1 (da) | 1998-02-02 |
ZA892877B (en) | 1989-12-27 |
AU3318389A (en) | 1989-10-26 |
MC2025A1 (fr) | 1990-04-25 |
PT90308B (pt) | 1994-10-31 |
FI891865A0 (fi) | 1989-04-19 |
DK189189A (da) | 1989-10-21 |
EP0338444B1 (de) | 1993-11-24 |
IE62778B1 (en) | 1995-02-22 |
JPH01311024A (ja) | 1989-12-15 |
ES2060685T3 (es) | 1994-12-01 |
JP2950845B2 (ja) | 1999-09-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19940411 |
|
PC3A | Transfer or assignment |
Free format text: ASTA MEDICA HEALTH PRODUCTS GMBH & CO. KG DE Effective date: 20020909 |
|
PD3A | Change of proprietorship |
Free format text: VIATRIS GMBH & CO. KG DE Effective date: 20020909 Free format text: ASTA MEDICA GMBH DE Effective date: 20020909 |
|
TE3A | Change of address (patent) |
Free format text: ASTA MEDICA AKTIENGESELLSCHAFT DE Effective date: 20020909 |
|
TE3A | Change of address (patent) |
Free format text: VIATRIS GMBH & CO. KG DE Effective date: 20050506 |
|
PD4A | Change of proprietorship |
Owner name: MEDA PHARMA GMBH & CO. KG, DE Effective date: 20070604 |
|
MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20090419 |