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PT83356B - Processo para a preparacao de antibioticos macrociclicos - Google Patents

Processo para a preparacao de antibioticos macrociclicos

Info

Publication number
PT83356B
PT83356B PT83356A PT8335686A PT83356B PT 83356 B PT83356 B PT 83356B PT 83356 A PT83356 A PT 83356A PT 8335686 A PT8335686 A PT 8335686A PT 83356 B PT83356 B PT 83356B
Authority
PT
Portugal
Prior art keywords
preparation
macrocyclic antibiotics
hydroxy
compounds
macrocyclic
Prior art date
Application number
PT83356A
Other languages
English (en)
Other versions
PT83356A (en
Original Assignee
Ciba Geigy Ag
Biotechnolog Forschung Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag, Biotechnolog Forschung Gmbh filed Critical Ciba Geigy Ag
Publication of PT83356A publication Critical patent/PT83356A/pt
Publication of PT83356B publication Critical patent/PT83356B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623Avermectin; Milbemycin; Ivermectin; C-076

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT83356A 1985-09-13 1986-09-11 Processo para a preparacao de antibioticos macrociclicos PT83356B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH398685 1985-09-13

Publications (2)

Publication Number Publication Date
PT83356A PT83356A (en) 1986-10-01
PT83356B true PT83356B (pt) 1989-05-12

Family

ID=4267667

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83356A PT83356B (pt) 1985-09-13 1986-09-11 Processo para a preparacao de antibioticos macrociclicos

Country Status (9)

Country Link
US (2) US4987072A (pt)
EP (1) EP0216731B1 (pt)
JP (1) JPS62181281A (pt)
AT (1) ATE51003T1 (pt)
DE (1) DE3669515D1 (pt)
DK (1) DK162390C (pt)
ES (1) ES2001783A6 (pt)
GR (1) GR862324B (pt)
PT (1) PT83356B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0358607A3 (de) * 1988-09-09 1990-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF) Mikrobizide makrozyklische Laktonderivate
EP0358608A3 (de) * 1988-09-09 1990-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF) Mikrobizide makrozyklische Laktonderivate
EP0358606A3 (de) * 1988-09-09 1990-10-31 Gesellschaft für Biotechnologische Forschung mbH (GBF) Mikrobiologisches Verfahren zur Herstellung agrarchemisch verwendbarer mikrobizider makrozyklischer Lactonderivate
DE3930950A1 (de) * 1989-09-15 1991-03-28 Biotechnolog Forschung Gmbh Synthetische sorangicin-varianten und herstellungsverfahren
US5393897A (en) * 1993-07-02 1995-02-28 Arizona Board Of Regents Acting On Behalf Of Arizona State University Isolation and structure of spongistatins 5,7,8 and 9
US5380838A (en) * 1993-10-08 1995-01-10 Merck & Co. Inc. Stable solvates of avermectin compounds
US5478861A (en) * 1994-02-18 1995-12-26 Harbor Branch Oceanographic Institution, Inc. Cytotoxic macrolides and methods of use
US5684036A (en) * 1994-02-18 1997-11-04 Harbor Branch Oceanographic Institution, Inc. Cytotoxic macrolides and methods of use
US6194181B1 (en) * 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
KR20050053681A (ko) * 2002-09-23 2005-06-08 브리스톨-마이어스 스큅 컴퍼니 에포틸론 b의 제조, 분리 및 정제 방법, 및 에포틸론 b의x-선 결정 구조
JP2010110216A (ja) * 2007-02-20 2010-05-20 Ajinomoto Co Inc L−アミノ酸または核酸の製造方法
EP3498714B1 (en) 2017-12-14 2020-07-22 Helmholtz-Zentrum für Infektionsforschung GmbH Novel sorangicin antibiotic

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651216A (en) * 1970-05-11 1972-03-21 Warner Lambert Co Antibiotic substances produced by polyangium cellulosum var. fulvum
DE3700331A1 (de) * 1986-12-24 1988-07-07 Hoechst Ag Verfahren zur herstellung der desmalonylverbindung von makrolid-lactonen

Also Published As

Publication number Publication date
PT83356A (en) 1986-10-01
DK162390B (da) 1991-10-21
DK437886D0 (da) 1986-09-12
DK162390C (da) 1992-03-09
EP0216731A1 (de) 1987-04-01
JPS62181281A (ja) 1987-08-08
DE3669515D1 (de) 1990-04-19
US5096922A (en) 1992-03-17
ATE51003T1 (de) 1990-03-15
US4987072A (en) 1991-01-22
GR862324B (en) 1987-01-12
EP0216731B1 (de) 1990-03-14
DK437886A (da) 1987-03-14
ES2001783A6 (es) 1988-06-16

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19940430