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PT80786B - Process for preparing benzothiophene anti-diarrhoeal agents - Google Patents

Process for preparing benzothiophene anti-diarrhoeal agents

Info

Publication number
PT80786B
PT80786B PT80786A PT8078685A PT80786B PT 80786 B PT80786 B PT 80786B PT 80786 A PT80786 A PT 80786A PT 8078685 A PT8078685 A PT 8078685A PT 80786 B PT80786 B PT 80786B
Authority
PT
Portugal
Prior art keywords
diarrhoeal agents
preparing benzothiophene
benzothiophene
preparing
diarrhoeal
Prior art date
Application number
PT80786A
Other languages
English (en)
Other versions
PT80786A (en
Inventor
Stephen James Ray
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT80786A publication Critical patent/PT80786A/pt
Publication of PT80786B publication Critical patent/PT80786B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Organic Insulating Materials (AREA)
PT80786A 1984-07-10 1985-07-08 Process for preparing benzothiophene anti-diarrhoeal agents PT80786B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848417559A GB8417559D0 (en) 1984-07-10 1984-07-10 Anti-diarrhoeal agents

Publications (2)

Publication Number Publication Date
PT80786A PT80786A (en) 1985-08-01
PT80786B true PT80786B (en) 1987-03-26

Family

ID=10563672

Family Applications (1)

Application Number Title Priority Date Filing Date
PT80786A PT80786B (en) 1984-07-10 1985-07-08 Process for preparing benzothiophene anti-diarrhoeal agents

Country Status (20)

Country Link
US (1) US4654352A (pt)
EP (1) EP0169012A1 (pt)
JP (1) JPS6136281A (pt)
KR (1) KR860001094A (pt)
CN (1) CN85105193A (pt)
AU (1) AU556058B2 (pt)
CS (1) CS249545B2 (pt)
DD (1) DD238792A5 (pt)
DK (1) DK312485A (pt)
ES (1) ES8604557A1 (pt)
FI (1) FI852691L (pt)
GB (1) GB8417559D0 (pt)
GR (1) GR851688B (pt)
HU (1) HUT38330A (pt)
IL (1) IL75740A0 (pt)
NO (1) NO852760L (pt)
PL (1) PL254445A1 (pt)
PT (1) PT80786B (pt)
YU (1) YU113985A (pt)
ZA (1) ZA855153B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4128690A1 (de) * 1991-08-29 1993-03-04 Boehringer Mannheim Gmbh Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
AU683552B2 (en) * 1994-04-11 1997-11-13 Chugai Seiyaku Kabushiki Kaisha 4,6-DI-t-butyl-2,3-dihydrobenzothiophene derivative
CA2207141A1 (en) * 1996-07-15 1998-01-15 David Thompson Berg Benzothiophene compounds, and uses and formulations thereof
CA2207083A1 (en) * 1996-07-15 1998-01-15 Brian William Grinnell Benzothiophene compounds, and uses and formulations thereof
US5792798A (en) * 1996-07-29 1998-08-11 Eli Lilly And Company Method for inhibiting plasminogen activator inhibitor 1
WO1998037070A1 (fr) * 1997-02-21 1998-08-27 Takeda Chemical Industries, Ltd. Composes a anneaux condenses, leur procede de production et leur utilisation
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
EE200000653A (et) * 1998-05-12 2002-04-15 American Home Products Corporation Bensotiofeenid, bensofuraanid ja indoolid kasutamiseks insuliiniresistentsuse ning hüperglükeemia ravis
DK1334094T3 (da) * 2000-11-02 2005-05-02 Hoffmann La Roche Cholesterolsænkende benzo[b]thiophener og benzo[d]isothiazoler
US6969730B2 (en) 2001-03-16 2005-11-29 Abbott Laboratories Amines as histamine-3 receptor ligands and their therapeutic applications
US7393865B2 (en) * 2004-06-17 2008-07-01 Neurocrine Biosciences, Inc. Sleep inducing compounds and methods relating thereto
JP5180807B2 (ja) 2008-12-24 2013-04-10 三菱重工業株式会社 1段静翼の冷却構造、及びガスタービン

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1174411A (en) * 1966-03-02 1969-12-17 Aspro Nicholas Ltd Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture
US3598839A (en) * 1969-06-30 1971-08-10 Parke Davis & Co Phenylbenzothiophene compounds
US3944672A (en) * 1972-12-13 1976-03-16 Schering Corporation Method for treating microbial infections
ZA753324B (en) * 1974-05-28 1976-04-28 Scherico Ltd Antimicrobial compounds and compositions containing them
US4018893A (en) * 1974-05-28 1977-04-19 Schering Corporation Methods for treating microbial infections
US4137414A (en) * 1977-09-26 1979-01-30 G. D. Searle & Co. 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds

Also Published As

Publication number Publication date
JPS6136281A (ja) 1986-02-20
AU4471385A (en) 1986-01-16
ES544970A0 (es) 1986-02-01
US4654352A (en) 1987-03-31
EP0169012A1 (en) 1986-01-22
GB8417559D0 (en) 1984-08-15
PT80786A (en) 1985-08-01
ES8604557A1 (es) 1986-02-01
GR851688B (pt) 1985-11-26
CN85105193A (zh) 1987-01-28
YU113985A (en) 1987-08-31
CS249545B2 (en) 1987-03-12
DK312485D0 (da) 1985-07-09
DK312485A (da) 1986-01-11
HUT38330A (en) 1986-05-28
ZA855153B (en) 1987-02-25
KR860001094A (ko) 1986-02-22
NO852760L (no) 1986-01-13
PL254445A1 (en) 1986-07-15
FI852691A0 (fi) 1985-07-08
AU556058B2 (en) 1986-10-23
FI852691L (fi) 1986-01-11
DD238792A5 (de) 1986-09-03
IL75740A0 (en) 1985-11-29

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