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PT3921033T - Inibidores de arginase e métodos de utilização dos mesmos - Google Patents

Inibidores de arginase e métodos de utilização dos mesmos

Info

Publication number
PT3921033T
PT3921033T PT207097064T PT20709706T PT3921033T PT 3921033 T PT3921033 T PT 3921033T PT 207097064 T PT207097064 T PT 207097064T PT 20709706 T PT20709706 T PT 20709706T PT 3921033 T PT3921033 T PT 3921033T
Authority
PT
Portugal
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
PT207097064T
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT3921033T publication Critical patent/PT3921033T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT207097064T 2019-02-08 2020-02-07 Inibidores de arginase e métodos de utilização dos mesmos PT3921033T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962802765P 2019-02-08 2019-02-08

Publications (1)

Publication Number Publication Date
PT3921033T true PT3921033T (pt) 2023-10-11

Family

ID=69770954

Family Applications (1)

Application Number Title Priority Date Filing Date
PT207097064T PT3921033T (pt) 2019-02-08 2020-02-07 Inibidores de arginase e métodos de utilização dos mesmos

Country Status (29)

Country Link
US (1) US20220106335A1 (pt)
EP (1) EP3921033B1 (pt)
JP (1) JP7526734B2 (pt)
KR (1) KR20210126044A (pt)
CN (1) CN113395996B (pt)
AU (1) AU2020218651B2 (pt)
BR (1) BR112021015581A2 (pt)
CA (1) CA3127755A1 (pt)
CL (1) CL2021002056A1 (pt)
CO (1) CO2021011039A2 (pt)
CR (1) CR20210463A (pt)
DK (1) DK3921033T3 (pt)
DO (1) DOP2021000166A (pt)
EA (1) EA202192114A1 (pt)
ES (1) ES2960034T3 (pt)
FI (1) FI3921033T3 (pt)
HR (1) HRP20231092T1 (pt)
HU (1) HUE062968T2 (pt)
IL (1) IL285108B2 (pt)
LT (1) LT3921033T (pt)
MA (1) MA56324B1 (pt)
MX (1) MX2021009499A (pt)
PE (1) PE20220280A1 (pt)
PL (1) PL3921033T3 (pt)
PT (1) PT3921033T (pt)
RS (1) RS64781B1 (pt)
SG (1) SG11202108503PA (pt)
SI (1) SI3921033T1 (pt)
WO (1) WO2020161675A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202228720A (zh) 2020-12-22 2022-08-01 波蘭商昂科艾倫迪治療法股份公司 精胺酸酶抑制劑及其使用方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901572D0 (sv) * 1999-05-03 1999-05-03 Astra Ab New compounds
SE0300907D0 (sv) * 2003-03-31 2003-03-31 Astrazeneca Ab Novel compounds
SI2389352T1 (sl) * 2009-01-26 2019-08-30 The Trustees Of The University Of Pennsylvania, Center For Technology Transfer Inhibitorji arginaze in postopki uporabe
SG10201503168VA (en) * 2010-04-22 2015-06-29 Mars Inc Inhibitors of arginase and their therapeutic applications
EP3719024A1 (en) * 2010-10-26 2020-10-07 Mars, Incorporated Arginase inhibitors as therapeutics
AU2012326109A1 (en) * 2011-10-19 2014-05-29 Mars, Incorporated Inhibitors of arginase and their therapeutic applications
RU2018138195A (ru) * 2012-12-17 2018-12-18 Пэрион Сайенсиз, Инк. Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида
PL410665A1 (pl) * 2014-12-29 2016-07-04 Oncoarendi Therapeutics Spółka Z Ograniczoną Odpowiedzialnością Inhibitory arginazy oraz ich zastosowania terapeutyczne
CN107921051A (zh) * 2015-06-23 2018-04-17 卡里塞拉生物科学股份公司 抑制精氨酸酶活性的组合物和方法
WO2017175185A1 (en) * 2016-04-08 2017-10-12 Novartis Ag Heteroaryl butanoic acid derivatives as lta4h inhibitors
RS61996B1 (sr) 2016-12-22 2021-07-30 Calithera Biosciences Inc Kompozicije i postupci za inhibiranje aktivnosti arginaze
CN108794517B (zh) * 2017-04-27 2021-03-30 南京谷睿生物科技有限公司 一种精氨酸酶抑制剂及其制备方法与用途
EP3752251A1 (en) 2018-02-17 2020-12-23 AstraZeneca AB Arginase inhibitors and methods of use thereof
CN111770756B (zh) 2018-04-27 2023-03-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途
KR102668252B1 (ko) * 2018-08-22 2024-05-21 아스트라제네카 아베 아르기나제 저해제 및 이의 사용 방법

Also Published As

Publication number Publication date
CN113395996B (zh) 2024-05-28
ES2960034T3 (es) 2024-02-29
MX2021009499A (es) 2021-09-08
WO2020161675A1 (en) 2020-08-13
US20220106335A1 (en) 2022-04-07
CA3127755A1 (en) 2020-08-13
CR20210463A (es) 2021-10-15
SI3921033T1 (sl) 2023-11-30
BR112021015581A2 (pt) 2021-10-05
EP3921033B1 (en) 2023-07-26
KR20210126044A (ko) 2021-10-19
DK3921033T3 (da) 2023-10-16
EA202192114A1 (ru) 2021-12-01
CL2021002056A1 (es) 2022-03-04
AU2020218651A1 (en) 2021-09-30
CN113395996A (zh) 2021-09-14
JP2022521474A (ja) 2022-04-08
RS64781B1 (sr) 2023-11-30
FI3921033T3 (fi) 2023-09-15
IL285108B2 (en) 2024-10-01
SG11202108503PA (en) 2021-09-29
PL3921033T3 (pl) 2024-01-15
CO2021011039A2 (es) 2021-09-09
IL285108B1 (en) 2024-06-01
EP3921033A1 (en) 2021-12-15
PE20220280A1 (es) 2022-02-25
LT3921033T (lt) 2023-09-25
DOP2021000166A (es) 2021-09-30
MA56324B1 (fr) 2023-10-31
AU2020218651B2 (en) 2023-01-12
IL285108A (en) 2021-09-30
JP7526734B2 (ja) 2024-08-01
HUE062968T2 (hu) 2023-12-28
HRP20231092T1 (hr) 2023-12-22

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