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PT3023106T - Composição antigénica de micobactéria - Google Patents

Composição antigénica de micobactéria

Info

Publication number
PT3023106T
PT3023106T PT152011961T PT15201196T PT3023106T PT 3023106 T PT3023106 T PT 3023106T PT 152011961 T PT152011961 T PT 152011961T PT 15201196 T PT15201196 T PT 15201196T PT 3023106 T PT3023106 T PT 3023106T
Authority
PT
Portugal
Prior art keywords
antigenic composition
mycobacterium
mycobacterium antigenic
composition
antigenic
Prior art date
Application number
PT152011961T
Other languages
English (en)
Inventor
Andre Georges Godart Stephane
Ingrid Lemoine Dominique
Laanan Amina
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of PT3023106T publication Critical patent/PT3023106T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
PT152011961T 2010-12-14 2011-12-14 Composição antigénica de micobactéria PT3023106T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42272310P 2010-12-14 2010-12-14

Publications (1)

Publication Number Publication Date
PT3023106T true PT3023106T (pt) 2019-11-04

Family

ID=45346501

Family Applications (2)

Application Number Title Priority Date Filing Date
PT117947788T PT2651436E (pt) 2010-12-14 2011-12-14 Composição antigénica de micobactéria
PT152011961T PT3023106T (pt) 2010-12-14 2011-12-14 Composição antigénica de micobactéria

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT117947788T PT2651436E (pt) 2010-12-14 2011-12-14 Composição antigénica de micobactéria

Country Status (32)

Country Link
US (5) US9352030B2 (pt)
EP (4) EP3593813A1 (pt)
JP (2) JP5951633B2 (pt)
KR (3) KR20140029376A (pt)
CN (4) CN103249431B (pt)
AR (1) AR084285A1 (pt)
AU (2) AU2011343367B2 (pt)
BR (2) BR112013014599A2 (pt)
CA (2) CA2819298A1 (pt)
CO (2) CO6751287A2 (pt)
CY (1) CY1122187T1 (pt)
DK (3) DK2651436T3 (pt)
EA (2) EA027504B1 (pt)
ES (3) ES2748651T3 (pt)
HR (3) HRP20160362T1 (pt)
HU (3) HUE045766T2 (pt)
IL (2) IL226450A0 (pt)
LT (1) LT3023106T (pt)
ME (1) ME02380B (pt)
MX (2) MX344280B (pt)
MY (1) MY161412A (pt)
PL (3) PL2651437T3 (pt)
PT (2) PT2651436E (pt)
RS (1) RS54687B1 (pt)
SG (2) SG190731A1 (pt)
SI (3) SI2651436T1 (pt)
SM (1) SMT201600118B (pt)
TW (1) TW201305192A (pt)
UA (2) UA110806C2 (pt)
UY (1) UY33802A (pt)
WO (2) WO2012080369A1 (pt)
ZA (2) ZA201304015B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2524570T3 (es) 2005-04-29 2014-12-10 Glaxosmithkline Biologicals S.A. Procedimiento de prevención o tratamiento de infección por M. tuberculosis
RS54687B1 (en) * 2010-12-14 2016-08-31 Glaxosmithkline Biologicals S.A. COMPOSITION OF MYCOBACTERIAL ANTIGENS
WO2012093137A1 (en) 2011-01-04 2012-07-12 Archivel Farma, Sl Liposome formulation suitable for treating or preventing tuberculosis
DK2802345T3 (en) 2012-01-12 2018-04-30 Archivel Farma Sl MTB-C-VACCINE AGAINST ALLERGIC REACTIONS
US9993427B2 (en) 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
GB201405921D0 (en) 2014-04-02 2014-05-14 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
ES2759260T3 (es) 2014-04-23 2020-05-08 Juno Therapeutics Inc Métodos para aislar, cultivar y modificar genéticametne poblaciones de células inmunes para la terapia adoptiva
GB201513176D0 (en) 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
GB201522068D0 (en) 2015-12-15 2016-01-27 Glaxosmithkline Biolog Sa Dried composition
CN110035770B (zh) 2016-12-07 2023-06-16 葛兰素史密丝克莱恩生物有限公司 新方法
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
GB201707700D0 (en) 2017-05-12 2017-06-28 Glaxosmithkline Biologicals Sa Dried composition
IE20190086A1 (en) 2017-05-30 2019-12-25 Glaxosmithkline Biologicals Sa Novel methods for manufacturing an adjuvant
CA3083078A1 (en) 2017-12-01 2019-06-06 Glaxosmithkline Biologicals Sa Saponin purification
RU2728976C2 (ru) * 2018-03-22 2020-08-03 Зули Холдингз, Лтд. Липосомный состав и его получение
US20210292395A1 (en) 2018-07-31 2021-09-23 Glaxosmithkline Biologicals Sa Antigen purification method
EP3886901A1 (en) 2018-11-29 2021-10-06 GlaxoSmithKline Biologicals S.A. Methods for manufacturing an adjuvant
JP2022535091A (ja) 2019-06-05 2022-08-04 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム サポニン精製
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
CA3092525A1 (en) 2019-09-09 2021-03-09 Glaxosmithkline Biologicals S.A. Immunotherapeutic compositions
WO2021099982A1 (en) 2019-11-22 2021-05-27 Glaxosmithkline Biologicals Sa Dosage and administration of a bacterial saccharide glycoconjugate vaccine
CN115485057A (zh) 2020-05-05 2022-12-16 葛兰素史克生物有限公司 微流体混合装置和使用方法
US20230234992A1 (en) 2020-06-05 2023-07-27 Glaxosmithkline Biologicals Sa Modified betacoronavirus spike proteins
MX2023006769A (es) 2020-12-09 2023-08-18 Glaxosmithkline Biologicals Sa Modificacion de saponinas.
CN114034860A (zh) * 2021-11-01 2022-02-11 宁夏大学 一种结核分枝杆菌mtb39a蛋白抗体间接elisa检测方法及其试剂盒
WO2023242187A1 (en) 2022-06-15 2023-12-21 Glaxosmithkline Biologicals Sa Enzymatic modification of saponins
CN116120411B (zh) * 2022-12-07 2024-04-12 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌蛋白抗原混合物、多抗原融合蛋白及编码基因和应用

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4436727A (en) 1982-05-26 1984-03-13 Ribi Immunochem Research, Inc. Refined detoxified endotoxin product
US4866034A (en) 1982-05-26 1989-09-12 Ribi Immunochem Research Inc. Refined detoxified endotoxin
US4877611A (en) 1986-04-15 1989-10-31 Ribi Immunochem Research Inc. Vaccine containing tumor antigens and adjuvants
CA1331443C (en) 1987-05-29 1994-08-16 Charlotte A. Kensil Saponin adjuvant
US5278302A (en) 1988-05-26 1994-01-11 University Patents, Inc. Polynucleotide phosphorodithioates
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
ATE115862T1 (de) 1989-02-04 1995-01-15 Akzo Nobel Nv Tocole als impfstoffadjuvans.
CZ289476B6 (cs) 1993-03-23 2002-01-16 Smithkline Beecham Biologicals (S.A.) Očkovací přípravek a způsob jeho výroby
WO1995026204A1 (en) 1994-03-25 1995-10-05 Isis Pharmaceuticals, Inc. Immune stimulation by phosphorothioate oligonucleotide analogs
ATE420171T1 (de) 1994-07-15 2009-01-15 Univ Iowa Res Found Immunomodulatorische oligonukleotide
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
HU225979B1 (en) 1995-09-01 2008-02-28 Corixa Corp Compounds and methods for immunotherapy and diagnosis of tuberculosis
DE69636075D1 (de) 1995-09-01 2006-06-01 Corixa Corp Verbindungen und verfahren zur diagnose von tuberkulose
US5666153A (en) 1995-10-03 1997-09-09 Virtual Shopping, Inc. Retractable teleconferencing apparatus
GB9619613D0 (en) 1996-09-19 1996-10-30 Breed Automotive Tech An inflatable restraint for a vehicle
EP0859366A1 (en) 1997-02-12 1998-08-19 STMicroelectronics S.r.l. Associative memory device with optimized occupation, particularly for the recognition of words
NZ500028A (en) * 1997-04-08 2001-08-31 Merck & Co Inc Stabilized human papillomavirus formulations also containing a salt and a nonionic surfactant
US6764840B2 (en) 1997-05-08 2004-07-20 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
US6113918A (en) 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6303347B1 (en) 1997-05-08 2001-10-16 Corixa Corporation Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors
GB9727262D0 (en) 1997-12-24 1998-02-25 Smithkline Beecham Biolog Vaccine
DE19803453A1 (de) 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine
IL138809A0 (en) 1998-04-07 2001-10-31 Corixa Corp Fusion proteins of mycobacterium tuberculosis antigens and pharmaceutical compositions containing the same
AU746163B2 (en) * 1998-04-09 2002-04-18 Smithkline Beecham Biologicals (Sa) Adjuvant compositions
US20040006242A1 (en) 1999-02-01 2004-01-08 Hawkins Lynn D. Immunomodulatory compounds and method of use thereof
US6551600B2 (en) 1999-02-01 2003-04-22 Eisai Co., Ltd. Immunological adjuvant compounds compositions and methods of use thereof
CA2386841A1 (en) 1999-10-07 2001-04-12 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
ATE526994T1 (de) 2000-06-20 2011-10-15 Corixa Corp Mtb32a antigen aus mycobakterium tuberculosis mit inaktivierter protease aktivität und fusionsproteine die das antigen enthalten
SK288007B6 (sk) 2000-06-29 2012-10-02 Glaxosmithkline Biologicals S. A. Multivalent vaccine composition, process for its producing, and its use
AU2003213118A1 (en) * 2002-02-15 2003-09-09 Corixa Corporation Fusion proteins of mycobacterium tuberculosis
GB0411411D0 (en) 2004-05-21 2004-06-23 Glaxosmithkline Biolog Sa Vaccines
ES2524570T3 (es) 2005-04-29 2014-12-10 Glaxosmithkline Biologicals S.A. Procedimiento de prevención o tratamiento de infección por M. tuberculosis
WO2008140478A2 (en) * 2006-11-01 2008-11-20 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens
SI2148697T1 (sl) 2007-05-24 2013-01-31 Glaxosmithkline Biologicals S.A. Liofilizirani sestavek, ki vsebuje CpG in WT-1
NZ709704A (en) * 2007-11-30 2017-03-31 Abbvie Biotechnology Ltd Protein formulations and methods of making same
KR100955470B1 (ko) * 2008-01-09 2010-04-30 대한민국(관리부서 질병관리본부장) 탄저 방어 항원의 제조 방법
US8409901B2 (en) 2008-03-11 2013-04-02 The Royal Institution For The Advancement Of Learning/Mcgill University Low temperature wafer level processing for MEMS devices
GB0910046D0 (en) * 2009-06-10 2009-07-22 Glaxosmithkline Biolog Sa Novel compositions
GB0910045D0 (en) * 2009-06-10 2009-07-22 Glaxosmithkline Biolog Sa Novel compositions
GB201008512D0 (en) 2010-05-21 2010-07-07 Health Prot Agency Mycobacterial antigen composition
IT1400834B1 (it) 2010-07-07 2013-07-02 Aero Sekur S P A Metodo e sistema per l'atterraggio di emergenza di un veicolo, come un elicottero o simili.
RS54687B1 (en) 2010-12-14 2016-08-31 Glaxosmithkline Biologicals S.A. COMPOSITION OF MYCOBACTERIAL ANTIGENS
GB201400819D0 (en) 2014-01-17 2014-03-05 Sec Dep For Health The Mycobacterial antigen composition

Also Published As

Publication number Publication date
EP2651437B1 (en) 2016-02-10
JP5951633B2 (ja) 2016-07-13
IL226448A (en) 2017-09-28
UA110806C2 (uk) 2016-02-25
ZA201304015B (en) 2018-12-19
SI3023106T1 (sl) 2019-11-29
HRP20160362T1 (hr) 2016-05-06
HUE045766T2 (hu) 2020-01-28
HRP20191843T1 (hr) 2019-12-27
CN106822883A (zh) 2017-06-13
KR101951894B1 (ko) 2019-02-26
SI2651437T1 (sl) 2016-05-31
CO6751288A2 (es) 2013-09-16
CN103260642B (zh) 2018-03-16
SMT201600118B (it) 2016-07-01
US20160220656A1 (en) 2016-08-04
JP2014505036A (ja) 2014-02-27
EP3023106A1 (en) 2016-05-25
MX2013006819A (es) 2013-08-26
KR20140029376A (ko) 2014-03-10
PL2651437T3 (pl) 2016-07-29
DK2651436T3 (da) 2016-06-20
EP3593813A1 (en) 2020-01-15
ES2574403T3 (es) 2016-06-17
UY33802A (es) 2012-07-31
CN106822882A (zh) 2017-06-13
PL2651436T3 (pl) 2016-10-31
US20190183998A1 (en) 2019-06-20
US20130280289A1 (en) 2013-10-24
WO2012080370A1 (en) 2012-06-21
CO6751287A2 (es) 2013-09-16
EA027504B1 (ru) 2017-08-31
PL3023106T3 (pl) 2019-12-31
JP2013545783A (ja) 2013-12-26
AU2011343367B2 (en) 2015-05-21
MX2013006818A (es) 2013-08-26
MX344706B (es) 2017-01-03
US9730992B2 (en) 2017-08-15
JP5951634B2 (ja) 2016-07-13
BR112013014599A2 (pt) 2016-09-27
DK3023106T3 (da) 2019-09-30
HRP20160606T1 (hr) 2016-07-01
US9352030B2 (en) 2016-05-31
TW201305192A (zh) 2013-02-01
HUE027932T2 (en) 2016-11-28
EP2651436A1 (en) 2013-10-23
RS54687B1 (en) 2016-08-31
CN103249431B (zh) 2016-11-02
EA201390630A1 (ru) 2013-12-30
CN103260642A (zh) 2013-08-21
ES2748651T3 (es) 2020-03-17
CA2819297A1 (en) 2012-06-21
AR084285A1 (es) 2013-05-08
ME02380B (me) 2016-06-20
US10441648B2 (en) 2019-10-15
BR112013014598A2 (pt) 2017-09-19
US20130287809A1 (en) 2013-10-31
LT3023106T (lt) 2019-10-25
CY1122187T1 (el) 2020-11-25
MY161412A (en) 2017-04-14
UA110118C2 (uk) 2015-11-25
AU2011343367A1 (en) 2013-07-11
KR20130124525A (ko) 2013-11-14
MX344280B (es) 2016-12-09
ES2567190T3 (es) 2016-04-20
EP2651437A1 (en) 2013-10-23
CN103249431A (zh) 2013-08-14
AU2011343368B2 (en) 2015-08-20
SG190937A1 (en) 2013-07-31
IL226450A0 (en) 2013-07-31
PT2651436E (pt) 2016-06-08
ZA201304014B (en) 2017-04-26
EP3023106B1 (en) 2019-07-31
WO2012080369A1 (en) 2012-06-21
EA027920B1 (ru) 2017-09-29
SI2651436T1 (sl) 2016-07-29
AU2011343368C1 (en) 2015-12-24
EP2651436B1 (en) 2016-03-30
AU2011343368A1 (en) 2013-07-11
KR20190022897A (ko) 2019-03-06
DK2651437T3 (en) 2016-05-02
CA2819298A1 (en) 2012-06-21
EA201390631A1 (ru) 2014-11-28
US20180071378A1 (en) 2018-03-15
SG190731A1 (en) 2013-07-31
HUE028452T2 (en) 2016-12-28
IL226448A0 (en) 2013-07-31

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