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PT2814513T - Entrega sistémica e expressão regulada de genes parácrinos para doenças cardiovasculares e outras doenças - Google Patents

Entrega sistémica e expressão regulada de genes parácrinos para doenças cardiovasculares e outras doenças

Info

Publication number
PT2814513T
PT2814513T PT137496741T PT13749674T PT2814513T PT 2814513 T PT2814513 T PT 2814513T PT 137496741 T PT137496741 T PT 137496741T PT 13749674 T PT13749674 T PT 13749674T PT 2814513 T PT2814513 T PT 2814513T
Authority
PT
Portugal
Prior art keywords
paracrine
genes
conditions
cardiovascular diseases
systemic delivery
Prior art date
Application number
PT137496741T
Other languages
English (en)
Inventor
Kirk Hammond H
Hua Gao Mei
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of PT2814513T publication Critical patent/PT2814513T/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/575—Hormones
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
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PT137496741T 2012-02-14 2013-02-13 Entrega sistémica e expressão regulada de genes parácrinos para doenças cardiovasculares e outras doenças PT2814513T (pt)

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US201261598772P 2012-02-14 2012-02-14

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PT2814513T true PT2814513T (pt) 2018-03-02

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PT137496741T PT2814513T (pt) 2012-02-14 2013-02-13 Entrega sistémica e expressão regulada de genes parácrinos para doenças cardiovasculares e outras doenças

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Country Link
US (3) US20150118287A1 (pt)
EP (2) EP3311830A1 (pt)
JP (3) JP6562632B2 (pt)
KR (1) KR102107482B1 (pt)
CN (2) CN108310396B (pt)
AU (2) AU2013221615B2 (pt)
BR (1) BR112014020127A2 (pt)
CA (1) CA2864100A1 (pt)
DK (1) DK2814513T3 (pt)
ES (1) ES2660492T3 (pt)
HK (2) HK1203845A1 (pt)
HU (1) HUE036640T2 (pt)
IL (3) IL234007A0 (pt)
IN (1) IN2014DN06789A (pt)
PL (1) PL2814513T3 (pt)
PT (1) PT2814513T (pt)
RU (1) RU2642605C2 (pt)
WO (1) WO2013123094A2 (pt)

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