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PT2717898T - Compostos pró-coagulantes e processos para a sua utilização - Google Patents

Compostos pró-coagulantes e processos para a sua utilização

Info

Publication number
PT2717898T
PT2717898T PT12797036T PT12797036T PT2717898T PT 2717898 T PT2717898 T PT 2717898T PT 12797036 T PT12797036 T PT 12797036T PT 12797036 T PT12797036 T PT 12797036T PT 2717898 T PT2717898 T PT 2717898T
Authority
PT
Portugal
Prior art keywords
pro
methods
coagulant compounds
coagulant
compounds
Prior art date
Application number
PT12797036T
Other languages
English (en)
Inventor
Thorn Karina
G Toby Garabet
R Mezo Adam
Original Assignee
Bioverativ Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Therapeutics Inc filed Critical Bioverativ Therapeutics Inc
Publication of PT2717898T publication Critical patent/PT2717898T/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
PT12797036T 2011-06-10 2012-06-09 Compostos pró-coagulantes e processos para a sua utilização PT2717898T (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161495818P 2011-06-10 2011-06-10
US201161496541P 2011-06-13 2011-06-13
US201161496540P 2011-06-13 2011-06-13
US201161496543P 2011-06-13 2011-06-13
US201161496542P 2011-06-13 2011-06-13
US201261600237P 2012-02-17 2012-02-17
US201261605540P 2012-03-01 2012-03-01

Publications (1)

Publication Number Publication Date
PT2717898T true PT2717898T (pt) 2019-05-20

Family

ID=47296790

Family Applications (1)

Application Number Title Priority Date Filing Date
PT12797036T PT2717898T (pt) 2011-06-10 2012-06-09 Compostos pró-coagulantes e processos para a sua utilização

Country Status (14)

Country Link
US (1) US9486507B2 (pt)
EP (2) EP2717898B1 (pt)
AU (1) AU2012267484B2 (pt)
CA (1) CA2838833A1 (pt)
CY (1) CY1121509T1 (pt)
DK (1) DK2717898T3 (pt)
ES (1) ES2724778T3 (pt)
HR (1) HRP20190494T1 (pt)
HU (1) HUE043894T2 (pt)
LT (1) LT2717898T (pt)
PL (1) PL2717898T3 (pt)
PT (1) PT2717898T (pt)
SI (1) SI2717898T1 (pt)
WO (1) WO2012170969A2 (pt)

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EP3521321B1 (en) 2012-04-11 2020-11-04 Bioverativ Therapeutics Inc. Methods of detecting glycosaminoglycans
EP2858659B1 (en) 2012-06-08 2019-12-25 Bioverativ Therapeutics Inc. Procoagulant compounds
EP2863940A4 (en) 2012-06-08 2016-08-10 Biogen Ma Inc CHIMERIC COAGULATION FACTORS
WO2014190305A2 (en) 2013-05-24 2014-11-27 Biogen Idec Ma Inc. Anti-gpiib/iiia antibodies or uses thereof
TW201536811A (zh) * 2013-05-31 2015-10-01 Biogen Idec Inc 嵌合ｆｖｉｉ－ｘｔｅｎ分子及其用途
US9340582B2 (en) * 2013-07-25 2016-05-17 Novartis Ag Bioconjugates of synthetic apelin polypeptides
US10548953B2 (en) 2013-08-14 2020-02-04 Bioverativ Therapeutics Inc. Factor VIII-XTEN fusions and uses thereof
EP3065769A4 (en) * 2013-11-08 2017-05-31 Biogen MA Inc. Procoagulant fusion compound
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WO2016118577A1 (en) * 2015-01-22 2016-07-28 Medimmune, Llc Thymosin-beta-four fusion proteins
UA126016C2 (uk) 2015-08-03 2022-08-03 Біовератів Терапеутікс Інк. Злитий білок фактора іх
CN108135968A (zh) 2015-08-28 2018-06-08 阿穆尼克斯运营公司 嵌合多肽组装体及其制备和使用方法
WO2017096341A2 (en) * 2015-12-04 2017-06-08 The Texas A&M University System Adenovirus-vectored multivalent vaccine
US10557160B2 (en) 2015-12-15 2020-02-11 Board Of Regents, The University Of Texas System Transgenic bacteria with expanded amino acid usage and nucleic acid molecules for use in the same
CN114887074A (zh) 2016-04-06 2022-08-12 阿特根公司 包含修饰抗体的抗体-药物缀合物
WO2017176007A1 (ko) * 2016-04-06 2017-10-12 (주)알테오젠 변형항체를 포함하는 항체-약물 접합체
WO2018013481A1 (en) * 2016-07-11 2018-01-18 Board Of Regents, The University Of Texas System Recombinant polypeptides comprising selenocysteine and method for producing the same
CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
CN107759694B (zh) 2016-08-19 2023-01-13 安源医药科技（上海）有限公司 双特异性抗体及其制备方法与用途
CN109803679A (zh) 2016-08-30 2019-05-24 得克萨斯州大学系统董事会 在基因组重新编码生物体中生产硒代生物制剂
WO2018102317A1 (en) * 2016-11-29 2018-06-07 The Regents Of The University Of California Modulation of p53 for the treatment of cancer
WO2018191582A1 (en) * 2017-04-13 2018-10-18 The Board Of Trustees Of The University Of Illinois Assay for quantifying polyphosphates
CN112512555A (zh) 2018-05-18 2021-03-16 比奥维拉迪维治疗股份有限公司 治疗血友病a的方法
EP3870215A1 (en) * 2018-10-26 2021-09-01 Vrije Universiteit Brussel New tools for improving gene therapy and use thereof
CN109507966A (zh) * 2018-11-20 2019-03-22 东华大学 一种面向纬编面料生产的智能管控系统
CN113101413B (zh) * 2020-01-13 2022-04-08 中国科学院苏州纳米技术与纳米仿生研究所 有序水凝胶纤维支架、其制备方法及应用

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EP2717898A2 (en) 2014-04-16
EP2717898A4 (en) 2014-11-26
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WO2012170969A2 (en) 2012-12-13
WO2012170969A3 (en) 2013-08-15
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US20140303084A1 (en) 2014-10-09
US9486507B2 (en) 2016-11-08
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AU2012267484A1 (en) 2014-01-16
LT2717898T (lt) 2019-03-25

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