PT2299822T - Método para o tratamento da disfunção neurodegenerativa - Google Patents
Método para o tratamento da disfunção neurodegenerativaInfo
- Publication number
- PT2299822T PT2299822T PT97433213T PT09743321T PT2299822T PT 2299822 T PT2299822 T PT 2299822T PT 97433213 T PT97433213 T PT 97433213T PT 09743321 T PT09743321 T PT 09743321T PT 2299822 T PT2299822 T PT 2299822T
- Authority
- PT
- Portugal
- Prior art keywords
- treating neurodegenerative
- neurodegenerative dysfunction
- dysfunction
- treating
- neurodegenerative
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/151,200 US9314469B2 (en) | 2008-05-05 | 2008-05-05 | Method for treating neurocognitive dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2299822T true PT2299822T (pt) | 2017-10-30 |
Family
ID=41257496
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT17176372T PT3246031T (pt) | 2008-05-05 | 2009-04-30 | Método para tratar disfunção neurocognitiva |
| PT97433213T PT2299822T (pt) | 2008-05-05 | 2009-04-30 | Método para o tratamento da disfunção neurodegenerativa |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT17176372T PT3246031T (pt) | 2008-05-05 | 2009-04-30 | Método para tratar disfunção neurocognitiva |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US9314469B2 (pt) |
| EP (2) | EP3246031B1 (pt) |
| CA (1) | CA2723688C (pt) |
| ES (2) | ES2644511T3 (pt) |
| PT (2) | PT3246031T (pt) |
| WO (1) | WO2009137334A2 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2501234T3 (en) * | 2009-11-20 | 2017-12-04 | Tonix Pharma Holdings Ltd | METHODS AND COMPOSITIONS FOR TREATING SYMPTOMS CONNECTED WITH POSTTRAUMATIC LOAD RESPONSE USING CYCLOBENZAPRINE |
| US20110319389A1 (en) | 2010-06-24 | 2011-12-29 | Tonix Pharmaceuticals, Inc. | Methods and compositions for treating fatigue associated with disordered sleep using very low dose cyclobenzaprine |
| US11998516B2 (en) | 2011-03-07 | 2024-06-04 | Tonix Pharma Holdings Limited | Methods and compositions for treating depression using cyclobenzaprine |
| GB201106520D0 (en) * | 2011-04-18 | 2011-06-01 | Numedicus Ltd | Pharmaceutical compounds |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| TWI661825B (zh) | 2013-03-15 | 2019-06-11 | 托尼克製藥有限公司 | 環苯扎林鹽酸鹽及阿密替林鹽酸鹽之共晶調配物 |
| WO2016044796A1 (en) | 2014-09-18 | 2016-03-24 | Seth Lederman | Eutectic formulations of cyclobenzaprine hydrochloride |
| WO2018122606A1 (en) | 2016-12-28 | 2018-07-05 | Tonix Pharma Holdings Limited | Tianeptine oxalate salts and polymorphs |
| AU2018383098A1 (en) | 2017-12-11 | 2020-05-28 | Tonix Pharma Holdings Limited | Cyclobenzaprine treatment for agitation, psychosis and cognitive decline in dementia and neurodegenerative conditions |
| WO2024206520A1 (en) * | 2023-03-27 | 2024-10-03 | Tonix Pharmaceuticals Holding Corp. | (s)-tianeptine and use in treating disorders and conditions associated with peroxisome proliferator-activated receptor |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821249A (en) | 1970-03-13 | 1974-06-28 | En Nom Collectif Science Union | Dibenzothiazefin derivatives |
| US3758528A (en) | 1970-03-13 | 1973-09-11 | Science Union & Cie | Tricyclic compounds |
| FR2594827B1 (fr) | 1986-02-21 | 1988-05-20 | Adir | Nouveau derive tricyclique denomme acide ((chloro-3 methyl-6 dioxo-5,5 dihydro-6, 11 dibenzo (c,f) thiazepine (1,2) yl-11 amino)-5 pentazoique, son procede de preparation et les compositions pharmaceutiques qui le contiennent |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US5354566A (en) | 1993-06-02 | 1994-10-11 | Kraft General Foods, Inc. | Preparation of yeast-leavened dough crusts |
| US5405842A (en) * | 1994-01-28 | 1995-04-11 | Silverman; Bernard A. | Treatment of steroid dependent asthmatics |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| FR2747921B1 (fr) | 1996-04-24 | 1998-10-30 | Adir | Comprime matriciel permettant la liberation prolongee du sel de sodium de tianeptine apres administration par voie orale |
| FR2791891A1 (fr) | 1999-04-07 | 2000-10-13 | Adir | Utilisation de la tianeptine pour l'obtention de medicaments destines au traitement des pathologies de la neurodegenerescence |
| FR2807039A1 (fr) | 2000-03-31 | 2001-10-05 | Adir | NOUVEAU PROCEDE DE PREPARATION DE LA 11-AMINO-3-CHLORO-6,11- DIHYDRO-5,5-DIOXO-6-METHYL-DIBENZO[c,f][1,2]-THIAZEPINE ET APPLICATION A LA SYNTHESE DE LA TIANEPTINE |
| TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| US20050227961A1 (en) | 2004-04-08 | 2005-10-13 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome |
| EP1752143A1 (en) | 2005-08-08 | 2007-02-14 | NewThera | Novel uses for drugs targeting glutamine synthetase |
-
2008
- 2008-05-05 US US12/151,200 patent/US9314469B2/en active Active
-
2009
- 2009-04-30 WO PCT/US2009/042386 patent/WO2009137334A2/en active Application Filing
- 2009-04-30 PT PT17176372T patent/PT3246031T/pt unknown
- 2009-04-30 ES ES09743321.3T patent/ES2644511T3/es active Active
- 2009-04-30 CA CA2723688A patent/CA2723688C/en active Active
- 2009-04-30 EP EP17176372.5A patent/EP3246031B1/en active Active
- 2009-04-30 PT PT97433213T patent/PT2299822T/pt unknown
- 2009-04-30 EP EP09743321.3A patent/EP2299822B1/en active Active
- 2009-04-30 ES ES17176372T patent/ES2727851T3/es active Active
-
2016
- 2016-03-08 US US15/064,196 patent/US20160256471A1/en not_active Abandoned
-
2020
- 2020-07-24 US US16/937,919 patent/US20210177862A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3246031B1 (en) | 2019-02-27 |
| CA2723688C (en) | 2018-06-19 |
| ES2727851T3 (es) | 2019-10-21 |
| WO2009137334A3 (en) | 2009-12-30 |
| US9314469B2 (en) | 2016-04-19 |
| ES2644511T3 (es) | 2017-11-29 |
| US20210177862A1 (en) | 2021-06-17 |
| PT3246031T (pt) | 2019-05-29 |
| EP2299822A2 (en) | 2011-03-30 |
| WO2009137334A2 (en) | 2009-11-12 |
| EP3246031A1 (en) | 2017-11-22 |
| EP2299822A4 (en) | 2011-10-26 |
| CA2723688A1 (en) | 2009-11-12 |
| EP2299822B1 (en) | 2017-07-26 |
| US20160256471A1 (en) | 2016-09-08 |
| US20090275541A1 (en) | 2009-11-05 |
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