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PT2013204E - Análogos de 2-aminopiridina como activadores da glucoquinase - Google Patents

Análogos de 2-aminopiridina como activadores da glucoquinase Download PDF

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Publication number
PT2013204E
PT2013204E PT77540219T PT07754021T PT2013204E PT 2013204 E PT2013204 E PT 2013204E PT 77540219 T PT77540219 T PT 77540219T PT 07754021 T PT07754021 T PT 07754021T PT 2013204 E PT2013204 E PT 2013204E
Authority
PT
Portugal
Prior art keywords
glucokinase activators
aminopyridine
analogs
aminopyridine analogs
glucokinase
Prior art date
Application number
PT77540219T
Other languages
English (en)
Inventor
Thomas Daniel Aicher
Steven Armen Boyd
Ronald Jay Hinklin
Ajay Singh
Mark Joseph Chicarelli
Kevin Ronald Condroski
Original Assignee
Array Biopharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc
Publication of PT2013204E publication Critical patent/PT2013204E/pt

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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
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  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
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  • Gynecology & Obstetrics (AREA)
PT77540219T 2006-03-24 2007-03-23 Análogos de 2-aminopiridina como activadores da glucoquinase PT2013204E (pt)

Applications Claiming Priority (1)

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US78546006P 2006-03-24 2006-03-24

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PT2013204E true PT2013204E (pt) 2015-06-09

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US (3) US8022223B2 (pt)
EP (2) EP2013204B1 (pt)
JP (2) JP5377284B2 (pt)
KR (1) KR101440634B1 (pt)
CN (1) CN101437816B (pt)
AU (1) AU2007235558B2 (pt)
BR (1) BRPI0709171A2 (pt)
CA (1) CA2647208C (pt)
DK (1) DK2013204T3 (pt)
ES (1) ES2536547T3 (pt)
HK (1) HK1128130A1 (pt)
HR (1) HRP20150347T1 (pt)
IL (1) IL194160A (pt)
MX (1) MX2008012168A (pt)
MY (1) MY148985A (pt)
NZ (1) NZ571997A (pt)
PL (1) PL2013204T3 (pt)
PT (1) PT2013204E (pt)
RS (1) RS53981B1 (pt)
RU (1) RU2457207C2 (pt)
SG (1) SG170775A1 (pt)
SI (1) SI2013204T1 (pt)
TW (1) TWI393718B (pt)
UA (1) UA103746C2 (pt)
WO (1) WO2007117381A2 (pt)
ZA (1) ZA200809017B (pt)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2013204E (pt) 2006-03-24 2015-06-09 Array Biopharma Inc Análogos de 2-aminopiridina como activadores da glucoquinase
US8431713B2 (en) * 2007-01-24 2013-04-30 Array Biopharma, Inc. 2-aminopyridine derivatives as glucokinase activators
WO2008118718A2 (en) * 2007-03-23 2008-10-02 Array Biopharma Inc. 2-aminopyridine analogs as glucokinase activators
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2009042435A1 (en) * 2007-09-21 2009-04-02 Array Biopharma Inc. Pyridin-2 -yl-amino-i, 2, 4 -thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus
WO2009046784A1 (en) * 2007-10-09 2009-04-16 Merck Patent Gmbh Pyridine derivatives useful as glucokinase activators
BRPI0908124A2 (pt) * 2008-02-06 2015-08-04 Daiichi Sankyo Co Ltd Composto, ativador de glucoquinase, composição farmacêutica, uso de um composto ou sal farmacologicamente aceitavél do mesmo, e, métodos de ativação da glucoquinase, e para tratar e/ou prevenir uma doença
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
EP2553086B1 (en) 2010-03-31 2017-04-19 The Scripps Research Institute Reprogramming cells
US8178689B2 (en) 2010-06-17 2012-05-15 Hoffman-La Roche Inc. Tricyclic compounds
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