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PT1287819E - Processo para o revestimento antibiótico de corpos com microporos inteligados bem como corpos assim revestidos e sua utilização - Google Patents

Processo para o revestimento antibiótico de corpos com microporos inteligados bem como corpos assim revestidos e sua utilização Download PDF

Info

Publication number
PT1287819E
PT1287819E PT02018323T PT02018323T PT1287819E PT 1287819 E PT1287819 E PT 1287819E PT 02018323 T PT02018323 T PT 02018323T PT 02018323 T PT02018323 T PT 02018323T PT 1287819 E PT1287819 E PT 1287819E
Authority
PT
Portugal
Prior art keywords
antibiotic
sulfate
sulfonate
aqueous
impregnation
Prior art date
Application number
PT02018323T
Other languages
English (en)
Inventor
F Vogt Dr Sebastian
Schnabelrauch Dr Matthias
Kuehn Dr Klaus-Dieter
Original Assignee
Heraeus Kulzer Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2001142464 external-priority patent/DE10142464A1/de
Application filed by Heraeus Kulzer Gmbh filed Critical Heraeus Kulzer Gmbh
Publication of PT1287819E publication Critical patent/PT1287819E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Prostheses (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
PT02018323T 2001-08-31 2002-08-14 Processo para o revestimento antibiótico de corpos com microporos inteligados bem como corpos assim revestidos e sua utilização PT1287819E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2001142464 DE10142464A1 (de) 2001-08-31 2001-08-31 Verfahren zur antibiotischen Beschichtung von nichtmetallischen Körpern mit interkonnektierenden Mikrohohlräumen sowie nichtmetallischer Körper und seine Verwendung
DE10204308 2002-02-01

Publications (1)

Publication Number Publication Date
PT1287819E true PT1287819E (pt) 2008-05-19

Family

ID=26010027

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02018323T PT1287819E (pt) 2001-08-31 2002-08-14 Processo para o revestimento antibiótico de corpos com microporos inteligados bem como corpos assim revestidos e sua utilização

Country Status (29)

Country Link
US (1) US7358232B2 (pt)
EP (1) EP1287819B1 (pt)
JP (2) JP4041367B2 (pt)
CN (1) CN1197630C (pt)
AT (1) ATE390120T1 (pt)
AU (1) AU2002300639B2 (pt)
BG (1) BG65793B1 (pt)
BR (1) BR0203416A (pt)
CA (1) CA2396151C (pt)
CZ (1) CZ301805B6 (pt)
DE (1) DE50211948D1 (pt)
DK (1) DK1287819T3 (pt)
EE (1) EE200200492A (pt)
ES (1) ES2301595T3 (pt)
GE (1) GEP20043332B (pt)
HR (1) HRP20020679A2 (pt)
HU (1) HUP0202915A3 (pt)
IL (1) IL150998A (pt)
IS (1) IS6389A (pt)
MD (1) MD2670C2 (pt)
MX (1) MXPA02008327A (pt)
NO (1) NO20024103L (pt)
NZ (1) NZ521042A (pt)
PL (1) PL206971B1 (pt)
PT (1) PT1287819E (pt)
RU (1) RU2236871C2 (pt)
SA (1) SA02230289B1 (pt)
SK (1) SK287128B6 (pt)
YU (1) YU52002A (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070134287A1 (en) * 2005-12-09 2007-06-14 Biomet Manufacturing Corp Method for coating biocompatible substrates with antibiotics
DE102005061290B4 (de) * 2005-12-20 2021-03-18 Heraeus Medical Gmbh Verfahren zur Herstellung von Antibiotikum-/Antibiotika-Partikeln und deren Verwendung
JP5161452B2 (ja) 2006-10-03 2013-03-13 日本コヴィディエン株式会社 医療用具の製造方法、医療用具の表面に抗生物質を付与する方法および医療用具
US20100092537A1 (en) * 2006-11-10 2010-04-15 Stroemme Maria Surgical implant composite materials and kits and methods of manufacture
DE102010020940B4 (de) * 2010-05-19 2014-09-25 Heraeus Medical Gmbh Antibiotische Beschichtung
EP2988793B1 (en) 2013-04-22 2019-01-02 Stryker European Holdings I, LLC Method for drug loading hydroxyapatite coated implant surfaces
EP3010557B1 (en) 2013-06-21 2019-08-21 Stryker European Holdings I, LLC Co-precipitation of tobramycin into hydroxyapatite coatings
WO2015003756A1 (en) 2013-07-11 2015-01-15 Stryker Leibinger Gmbh & Co. Kg Fixation assembly with a flexible elongated member for securing parts of a sternum
WO2015028100A1 (en) 2013-09-02 2015-03-05 Stryker Trauma Gmbh Method of manufacturing an implant for use in a surgical procedure
EP3042622B1 (en) 2015-01-09 2018-05-09 Stryker European Holdings I, LLC Implant for bone fixation
EP3320868B1 (en) 2016-11-11 2019-05-01 Stryker European Holdings I, LLC Implant for bone fixation
US11198831B2 (en) 2019-01-31 2021-12-14 Kvi Llc Lubricant for a device

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US183265A (en) * 1876-10-17 Improvement in swinging outriggers for row-boats
US3091572A (en) * 1962-07-16 1963-05-28 Schering Corp Gentamycin and method of production
ES315101A1 (es) 1965-07-08 1966-01-01 Folch Vazquez Conrado Procedimiento de preparaciën de nuevos derivados de tetraciclina
CA950831A (en) 1972-04-25 1974-07-09 Leonard D. Kurtz Biocidal salts
FR2272680B1 (pt) 1974-05-29 1978-07-21 Hosbon Sa Lab
DE2843963A1 (de) * 1978-10-09 1980-04-24 Merck Patent Gmbh Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin
DE2807132C2 (de) * 1978-02-20 1983-11-03 Battelle-Institut E.V., 6000 Frankfurt Implantierbares Pharmaka-Depot
DE3206725A1 (de) * 1981-05-13 1982-12-02 Merck Patent Gmbh, 6100 Darmstadt Schwer loesliche salze von aminoglykosidantibiotika
DE3206726A1 (de) 1982-02-25 1983-09-01 Merck Patent Gmbh, 6100 Darmstadt Pharmakadepot
DE3248328A1 (de) 1982-12-28 1984-06-28 Bayer Ag, 5090 Leverkusen Schwerloesliche salze von aminoglykosiden sowie diese enthaltende formulierungen mit verzoegerter wirkstoff-freigabe
US4740382A (en) * 1984-07-23 1988-04-26 University Of Medicine & Dentistry Of New Jersey Antibiotic bonded prosthesis and process for producing same
US4879135A (en) * 1984-07-23 1989-11-07 University Of Medicine And Dentistry Of New Jersey Drug bonded prosthesis and process for producing same
FR2613619B1 (fr) * 1987-04-07 1993-10-15 Recherche Informatique Pharmacie Medicaments, produits dietetiques ou produits d'hygiene sous forme de compositions pulverulentes obtenues par adsorption de principes actifs sur un sucre a dissolution rapide
US5034421A (en) * 1988-12-13 1991-07-23 Fuisz Pharmaceutical Ltd. Moderated spun fibrous system and method of manufacture
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5169778A (en) * 1989-02-28 1992-12-08 Sawao Murao Amycolatopsis trehalostatica strain
HU208070B (en) * 1989-03-31 1993-08-30 Univ California Process for producing lipid suspension
GB9009473D0 (en) * 1990-04-27 1990-06-20 Beecham Group Plc Pharmaceutical formulation
DE69220317T2 (de) * 1991-10-01 1997-10-16 Takeda Chemical Industries Ltd Mikropartikeln-Zusammenfassung zur verlängerten Freigabe und Herstellung derselbe
AU4198793A (en) * 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
WO1994008599A1 (en) 1992-10-14 1994-04-28 The Regents Of The University Of Colorado Ion-pairing of drugs for improved efficacy and delivery
DE4314871A1 (de) * 1993-05-05 1994-11-10 Merck Patent Gmbh Lösungsmittel für ein schwerlösliches Gentamicin-Salz
EP0764169B1 (en) * 1994-06-10 1998-09-23 Dumex-Alpharma A/S Drug salts
US5693126A (en) * 1994-12-27 1997-12-02 Seiko Epson Corporation Water-base ink composition and process for producing the same
AU2676397A (en) 1996-04-18 1997-11-07 University Technology Corporation Methods for treating middle and inner ear disorders
DE10114245A1 (de) 2001-03-22 2002-10-02 Heraeus Kulzer Gmbh & Co Kg Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung

Also Published As

Publication number Publication date
HRP20020679A2 (en) 2003-06-30
HUP0202915A2 (hu) 2004-05-28
SK9952002A3 (en) 2003-03-04
JP4041367B2 (ja) 2008-01-30
HUP0202915A3 (en) 2004-06-28
NO20024103L (no) 2003-03-03
CA2396151C (en) 2008-10-14
PL355777A1 (en) 2003-03-10
US7358232B2 (en) 2008-04-15
JP2004267797A (ja) 2004-09-30
NO20024103D0 (no) 2002-08-28
IL150998A (en) 2010-06-30
CZ301805B6 (cs) 2010-06-30
MD20020154A (en) 2003-04-30
YU52002A (sh) 2005-06-10
BR0203416A (pt) 2003-05-27
ATE390120T1 (de) 2008-04-15
PL206971B1 (pl) 2010-10-29
ES2301595T3 (es) 2008-07-01
EP1287819A1 (de) 2003-03-05
IS6389A (is) 2003-03-03
GEP20043332B (en) 2004-05-10
SK287128B6 (sk) 2009-12-07
RU2236871C2 (ru) 2004-09-27
HU0202915D0 (pt) 2002-10-28
JP4808938B2 (ja) 2011-11-02
CN1406638A (zh) 2003-04-02
DE50211948D1 (de) 2008-05-08
RU2002123421A (ru) 2004-03-20
CN1197630C (zh) 2005-04-20
DK1287819T3 (da) 2008-06-02
MD2670B2 (en) 2005-01-31
MXPA02008327A (es) 2004-08-11
US20030049324A1 (en) 2003-03-13
IL150998A0 (en) 2003-02-12
BG65793B1 (bg) 2009-12-31
MD2670C2 (ro) 2005-08-31
SA02230289B1 (ar) 2008-07-19
AU2002300639B2 (en) 2005-08-18
CZ20022321A3 (cs) 2003-04-16
CA2396151A1 (en) 2003-02-28
JP2003070899A (ja) 2003-03-11
EE200200492A (et) 2003-04-15
EP1287819B1 (de) 2008-03-26
NZ521042A (en) 2003-03-28
BG106880A (en) 2003-12-31

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