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PT1165489E - Processo para a preparacao de gabapentina - Google Patents

Processo para a preparacao de gabapentina

Info

Publication number
PT1165489E
PT1165489E PT00910850T PT00910850T PT1165489E PT 1165489 E PT1165489 E PT 1165489E PT 00910850 T PT00910850 T PT 00910850T PT 00910850 T PT00910850 T PT 00910850T PT 1165489 E PT1165489 E PT 1165489E
Authority
PT
Portugal
Prior art keywords
gabapentin
retentate
solution
unsalified
addition
Prior art date
Application number
PT00910850T
Other languages
English (en)
Inventor
Nicola Caraccia
Franco Tenconi
Cristiana Giordani
Original Assignee
Bioindustria Lab Italiano Medi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioindustria Lab Italiano Medi filed Critical Bioindustria Lab Italiano Medi
Publication of PT1165489E publication Critical patent/PT1165489E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
PT00910850T 1999-03-26 2000-03-16 Processo para a preparacao de gabapentina PT1165489E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI000625A IT1311984B1 (it) 1999-03-26 1999-03-26 Procedimento per la preparzione di gabapentin.

Publications (1)

Publication Number Publication Date
PT1165489E true PT1165489E (pt) 2003-12-31

Family

ID=11382457

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00910850T PT1165489E (pt) 1999-03-26 2000-03-16 Processo para a preparacao de gabapentina

Country Status (11)

Country Link
US (1) US6576790B1 (pt)
EP (1) EP1165489B1 (pt)
AT (1) ATE247628T1 (pt)
AU (1) AU3290400A (pt)
CA (1) CA2368476C (pt)
DE (1) DE60004652T2 (pt)
DK (1) DK1165489T3 (pt)
ES (1) ES2204533T3 (pt)
IT (1) IT1311984B1 (pt)
PT (1) PT1165489E (pt)
WO (1) WO2000058268A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999059573A1 (en) * 1998-05-15 1999-11-25 Warner-Lambert Company Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivatives and process for preparing the same
ITMI20012750A1 (it) 2001-12-21 2003-06-21 Procos Spa Processo per la produzione dell'acido 1-(amminometil)-cicloesil-acetico in forma pura
AU2003262383A1 (en) * 2002-04-16 2003-11-03 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin
AU2002356424A1 (en) 2002-11-18 2004-06-15 Nicholas Piramal India Limited Improved process for preparation of gabapentin
ES2339756T3 (es) * 2002-11-20 2010-05-25 Hikal Ltd. Procedimiento mejorado para la preparacion de acidos aminometilcicloalcanaceticos.
US20070043236A1 (en) * 2003-05-19 2007-02-22 Chandiran Thakashina M Process for preparation of gabapentin
ITMI20031247A1 (it) * 2003-06-20 2004-12-21 Zambon Spa Processo per la purificazione di gabapentina
US20050187295A1 (en) * 2004-02-19 2005-08-25 Surendra Kalyan Processes for the preparation of gabapentin
ITMI20040579A1 (it) 2004-03-25 2004-06-25 Zambon Spa Processo di preparazione di gabapentina
ES2246159B1 (es) * 2004-07-22 2007-03-16 Menadiona, S.L. Procedimiento para la obtencion de aminoacidos ciclicos.
CN116693410B (zh) * 2023-06-08 2024-06-07 浙江竹子制药有限公司 一种粒径可控的加巴喷丁制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4894476A (en) * 1988-05-02 1990-01-16 Warner-Lambert Company Gabapentin monohydrate and a process for producing the same
US4960931A (en) * 1988-05-02 1990-10-02 Warner-Lambert Company Gabapentin mohohydrate and a process for producing the same
DE3928184A1 (de) * 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von cyclischen aminosaeurederivaten sowie zwischenprodukte
US5491259A (en) * 1994-09-13 1996-02-13 The Dow Chemical Company Process to produce aminocarboxylic acids containing low residual salt
IL119890A (en) 1996-12-24 2002-03-10 Teva Pharma Gabapentin form iii and preparation of gabapentin form ii

Also Published As

Publication number Publication date
DK1165489T3 (da) 2003-12-15
DE60004652D1 (de) 2003-09-25
ITMI990625A1 (it) 2000-09-26
IT1311984B1 (it) 2002-03-22
EP1165489A1 (en) 2002-01-02
US6576790B1 (en) 2003-06-10
ATE247628T1 (de) 2003-09-15
ES2204533T3 (es) 2004-05-01
EP1165489B1 (en) 2003-08-20
CA2368476A1 (en) 2000-10-05
CA2368476C (en) 2009-12-08
AU3290400A (en) 2000-10-16
DE60004652T2 (de) 2004-06-24
WO2000058268A1 (en) 2000-10-05

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