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PT1096951E - Utilizacao de proteases de bromelaina para a preparacao de um medicamento para a inibicao de coagulacao do sangue - Google Patents

Utilizacao de proteases de bromelaina para a preparacao de um medicamento para a inibicao de coagulacao do sangue

Info

Publication number
PT1096951E
PT1096951E PT98942559T PT98942559T PT1096951E PT 1096951 E PT1096951 E PT 1096951E PT 98942559 T PT98942559 T PT 98942559T PT 98942559 T PT98942559 T PT 98942559T PT 1096951 E PT1096951 E PT 1096951E
Authority
PT
Portugal
Prior art keywords
proteases
bromelaine
blood coagulation
medication
inhibition
Prior art date
Application number
PT98942559T
Other languages
English (en)
Inventor
Rainer Maurer
Klaus Eckert
Edyta Grabowska
Klaus Eschmann
Original Assignee
Ursapharm Arzneimittel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ursapharm Arzneimittel Gmbh filed Critical Ursapharm Arzneimittel Gmbh
Publication of PT1096951E publication Critical patent/PT1096951E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PT98942559T 1998-07-15 1998-07-15 Utilizacao de proteases de bromelaina para a preparacao de um medicamento para a inibicao de coagulacao do sangue PT1096951E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1998/004406 WO2000003729A1 (de) 1998-07-15 1998-07-15 Verwendung von bromelainproteasen zur hemmung der blutgerinnung

Publications (1)

Publication Number Publication Date
PT1096951E true PT1096951E (pt) 2003-01-31

Family

ID=8167005

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98942559T PT1096951E (pt) 1998-07-15 1998-07-15 Utilizacao de proteases de bromelaina para a preparacao de um medicamento para a inibicao de coagulacao do sangue

Country Status (10)

Country Link
US (1) US6803038B1 (pt)
EP (1) EP1096951B1 (pt)
AT (1) ATE222121T1 (pt)
AU (1) AU9066198A (pt)
CA (1) CA2333252C (pt)
DE (1) DE59805215D1 (pt)
DK (1) DK1096951T3 (pt)
ES (1) ES2182356T3 (pt)
PT (1) PT1096951E (pt)
WO (1) WO2000003729A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL165334A0 (en) * 2004-11-22 2006-01-15 Mediwound Ltd Debriding composition from bromelain and methods of producing same
EP2036978A1 (en) * 2007-09-14 2009-03-18 URSAPHARM Arzneimittel GmbH & Co. KG Recombinant preparation of selected bromelain fractions
DE102008062136B4 (de) * 2008-12-16 2012-05-03 Kamamed Ug Pharmazeutische Zusammensetzung auf Basis von Peptid aus Kamelmilch
RU2732224C9 (ru) 2016-01-31 2021-06-18 Медивунд Лтд. Раноочищающая композиция для лечения ран

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63295515A (ja) * 1987-05-26 1988-12-01 Kao Corp 腸溶性抗血液凝固・血栓溶解製剤
DE4130221C2 (de) 1991-09-11 1997-08-07 Mucos Pharma Gmbh Verwendung von proteolytischen Enzymen zur Herstellung eines Medikaments zur Behandlung von Autoimmun-Krankheiten, an deren Entstehung Proteine mit einer C¶H¶2-Domäne beteiligt sind
ES2138625T3 (es) * 1992-06-30 2000-01-16 Cortecs Uk Ltd Uso de enzimas especialmente bromelaina, en el tratamiento de diarrea no infecciosa.
DE4302060A1 (de) 1993-01-26 1994-07-28 Mucos Pharma Gmbh & Co Verwendung von Bromelain zur Krebstherapie und/oder Metastasen-Prophylaxe
GB9313188D0 (en) * 1993-06-25 1993-08-11 Cortecs Ltd Medical use of enzymes
GB9403344D0 (en) * 1994-02-22 1994-04-13 Cortecs Ltd Medical application of bromelain
JP2001513636A (ja) * 1997-02-25 2001-09-04 コルテクス（ユーケイ）リミティッド ブロメラインの成分
CN1204258C (zh) 1997-02-25 2005-06-01 科特克斯(英国)有限公司 菠萝蛋白酶成分

Also Published As

Publication number Publication date
CA2333252A1 (en) 2000-01-27
WO2000003729A1 (de) 2000-01-27
AU9066198A (en) 2000-02-07
CA2333252C (en) 2008-11-25
US6803038B1 (en) 2004-10-12
DE59805215D1 (de) 2002-09-19
EP1096951A1 (de) 2001-05-09
EP1096951B1 (de) 2002-08-14
DK1096951T3 (da) 2002-10-21
ES2182356T3 (es) 2003-03-01
ATE222121T1 (de) 2002-08-15

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