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PL3638680T3 - Związki heteroaromatyczne jako inhibitory waniny - Google Patents

Związki heteroaromatyczne jako inhibitory waniny

Info

Publication number
PL3638680T3
PL3638680T3 PL18731766.4T PL18731766T PL3638680T3 PL 3638680 T3 PL3638680 T3 PL 3638680T3 PL 18731766 T PL18731766 T PL 18731766T PL 3638680 T3 PL3638680 T3 PL 3638680T3
Authority
PL
Poland
Prior art keywords
heteroaromatic compounds
vanin
inhibitors
vanin inhibitors
heteroaromatic
Prior art date
Application number
PL18731766.4T
Other languages
English (en)
Inventor
Todd Bosanac
Michael J Burke
Brian Nicholas Cook
Darren Todd Disalvo
Thomas Martin Kirrane Jr.
Yue Shen
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of PL3638680T3 publication Critical patent/PL3638680T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL18731766.4T 2017-06-12 2018-06-08 Związki heteroaromatyczne jako inhibitory waniny PL3638680T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762518106P 2017-06-12 2017-06-12
PCT/EP2018/065140 WO2018228934A1 (en) 2017-06-12 2018-06-08 Heteroaromatic compounds as vanin inhibitors

Publications (1)

Publication Number Publication Date
PL3638680T3 true PL3638680T3 (pl) 2022-12-19

Family

ID=62631060

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18731766.4T PL3638680T3 (pl) 2017-06-12 2018-06-08 Związki heteroaromatyczne jako inhibitory waniny

Country Status (22)

Country Link
US (2) US10364255B2 (pl)
EP (1) EP3638680B1 (pl)
JP (1) JP6880243B2 (pl)
KR (1) KR102607934B1 (pl)
CN (1) CN110770242B (pl)
AR (1) AR112086A1 (pl)
AU (1) AU2018285131B2 (pl)
BR (1) BR112019021703A2 (pl)
CA (1) CA3066946A1 (pl)
CL (1) CL2019003515A1 (pl)
CO (1) CO2019013823A2 (pl)
DK (1) DK3638680T3 (pl)
EA (1) EA039223B1 (pl)
ES (1) ES2927021T3 (pl)
HU (1) HUE060597T2 (pl)
IL (1) IL271104B (pl)
MA (1) MA49374A (pl)
MX (1) MX2019014876A (pl)
PE (1) PE20200340A1 (pl)
PH (1) PH12019502693A1 (pl)
PL (1) PL3638680T3 (pl)
WO (1) WO2018228934A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3638680T3 (pl) * 2017-06-12 2022-12-19 Boehringer Ingelheim International Gmbh Związki heteroaromatyczne jako inhibitory waniny
FI3837263T3 (fi) 2018-08-13 2024-09-03 Hoffmann La Roche Uusia heterosyklisiä yhdisteitä monoasyyliglyserolilipaasin estäjinä
SG11202101749VA (en) 2018-08-28 2021-03-30 Boehringer Ingelheim Int Heteroaromatic compounds as vanin inhibitors
EP3891139A1 (en) 2018-12-03 2021-10-13 Boehringer Ingelheim International GmbH Heteroaromatic compounds as vanin inhibitors
JP2022548028A (ja) 2019-09-12 2022-11-16 エフ.ホフマン-ラ ロシュ アーゲー Magl阻害剤としての4,4a,5,7,8,8a-ヘキサピリド[4,3-b][1,4]オキサジン-3-オン化合物
WO2021174024A1 (en) 2020-02-28 2021-09-02 First Wave Bio, Inc. Methods of treating iatrogenic autoimmune colitis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005035524A1 (en) * 2003-10-09 2005-04-21 Abbott Laboratories Pyrrolidinyl urea derivatives as angiogensis inhibitors
CA2987179C (en) * 2015-05-29 2020-08-25 Pfizer Inc. Heterocyclic compounds as inhibitors of vanin-1 enzyme
EP3484876A1 (en) * 2016-07-14 2019-05-22 Pfizer Inc Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme
PL3638680T3 (pl) * 2017-06-12 2022-12-19 Boehringer Ingelheim International Gmbh Związki heteroaromatyczne jako inhibitory waniny

Also Published As

Publication number Publication date
AR112086A1 (es) 2019-09-18
EA202090014A1 (ru) 2020-05-12
WO2018228934A1 (en) 2018-12-20
AU2018285131B2 (en) 2021-11-11
US20180354968A1 (en) 2018-12-13
JP2020522517A (ja) 2020-07-30
CN110770242A (zh) 2020-02-07
EP3638680A1 (en) 2020-04-22
US20190263828A1 (en) 2019-08-29
US10364255B2 (en) 2019-07-30
PE20200340A1 (es) 2020-02-14
IL271104B (en) 2022-03-01
HUE060597T2 (hu) 2023-04-28
BR112019021703A2 (pt) 2020-05-12
CO2019013823A2 (es) 2020-01-17
EA039223B1 (ru) 2021-12-20
AU2018285131A1 (en) 2019-10-31
KR20200013718A (ko) 2020-02-07
CA3066946A1 (en) 2018-12-20
IL271104A (en) 2020-01-30
MA49374A (fr) 2021-04-21
JP6880243B2 (ja) 2021-06-02
ES2927021T3 (es) 2022-11-02
TW201920196A (zh) 2019-06-01
CN110770242B (zh) 2022-08-19
KR102607934B1 (ko) 2023-12-01
MX2019014876A (es) 2020-02-13
PH12019502693A1 (en) 2020-07-13
EP3638680B1 (en) 2022-08-10
DK3638680T3 (da) 2022-09-05
CL2019003515A1 (es) 2020-06-19

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