PL366034A1 - Il-8 receptor antagonists - Google Patents

Il-8 receptor antagonists

Info

Publication number: PL366034A1
Authority: PL; Poland
Prior art keywords: receptor antagonists; antagonists; receptor
Prior art date: 2000-03-16

Application number

PL01366034A

Other languages

Polish (pl)

Inventor

Katherine L. Widdowson

Qi Jin

Original Assignee

Smithkline Beecham Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-16

Filing date

2001-03-16

Publication date

2005-01-24

2001-03-16 Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation

2005-01-24 Publication of PL366034A1 publication Critical patent/PL366034A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/47—Y being a hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/22—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Dermatology (AREA)
Immunology (AREA)
Oncology (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Toxicology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)

PL01366034A 2000-03-16 2001-03-16 Il-8 receptor antagonists PL366034A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US18984800P	2000-03-16	2000-03-16
PCT/US2001/008672 WO2001068084A1 (en)	2000-03-16	2001-03-16	Il-8 receptor antagonists

Publications (1)

Publication Number	Publication Date
PL366034A1 true PL366034A1 (en)	2005-01-24

Family

ID=22699008

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL01366034A PL366034A1 (en)	2000-03-16	2001-03-16	Il-8 receptor antagonists

Country Status (23)

Country	Link
EP (1)	EP1263427A4 (en)
JP (1)	JP2003526664A (en)
KR (1)	KR20020091130A (en)
CN (1)	CN1424910A (en)
AP (1)	AP2002002606A0 (en)
AR (1)	AR031098A1 (en)
AU (1)	AU2001250873A1 (en)
BG (1)	BG107013A (en)
BR (1)	BR0108749A (en)
CA (1)	CA2403062A1 (en)
CO (1)	CO5280089A1 (en)
CZ (1)	CZ20023075A3 (en)
DZ (1)	DZ3317A1 (en)
EA (1)	EA200200981A1 (en)
HU (1)	HUP0300470A3 (en)
MA (1)	MA25659A1 (en)
MX (1)	MXPA02009094A (en)
NO (1)	NO20024367L (en)
OA (1)	OA12231A (en)
PL (1)	PL366034A1 (en)
SK (1)	SK13282002A3 (en)
WO (1)	WO2001068084A1 (en)
ZA (1)	ZA200207325B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR030689A1 (en) *	2000-03-14	2003-09-03	Smithkline Beecham Corp	3-AMINOSULFONIL-2-HYDROXIFENYL UREA COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM, AND USE OF SUCH COMPOUNDS IN THE MANUFACTURE OF MEDICINES TO TREAT CHEMIOQUINE MEDIUM DISEASES
AU2005245399A1 (en)	2004-05-12	2005-12-01	Schering Corporation	CXCR1 and CXCR2 chemokine antagonists
MX2008013600A (en) *	2006-04-21	2008-10-31	Smithkline Beechman Corp	Il-8 receptor antagonists.
CA2650007A1 (en) *	2006-04-21	2007-11-01	Smithkline Beecham Corporation	Il-8 receptor antagonists
CR20160557A (en)	2014-05-29	2017-01-20	Glaxosmithkline Ip Dev Ltd	COMPOUNDS DERIVED FROM 1- (CICLOPENT-2-EN-1-IL) -3- (2-HIDROXI-3- (ARILSULFONIL) PHENYL) UREA AS CXCR2 INHIBITORS
EP3174851A1 (en) *	2014-07-31	2017-06-07	GlaxoSmithKline Intellectual Property Management Limited	Use of cxcr2 antagonists for the prevention and/or treatment of chemotherapy induced peripheral neuropathy (cipn)
CN111727184B (en) *	2018-01-11	2022-06-28	深圳嘉科生物科技有限公司	CXCR2 antagonists
CN114286819B (en) *	2019-07-11	2024-03-05	深圳嘉科生物科技有限公司	Crystal form of CXCR2 antagonist and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0809492A4 (en) *	1995-02-17	2007-01-24	Smithkline Beecham Corp	Il-8 receptor antagonists
WO1997049680A1 (en) *	1996-06-27	1997-12-31	Smithkline Beecham Corporation	Il-8 receptor antagonists
EP1019035A4 (en) *	1996-08-21	2001-10-17	Smithkline Beecham Corp	Il-8 receptor antagonists
SK284757B6 (en) *	1998-09-23	2005-11-03	Tularik Inc.	Arylsulfonanilide ureas, pharmaceutical composition containing them and use thereof
UY25842A1 (en) *	1998-12-16	2001-04-30	Smithkline Beecham Corp	IL-8 RECEPTOR ANTAGONISTS

2001
- 2001-03-14 CO CO01020681A patent/CO5280089A1/en not_active Application Discontinuation
- 2001-03-14 AR ARP010101183A patent/AR031098A1/en unknown
- 2001-03-16 EA EA200200981A patent/EA200200981A1/en unknown
- 2001-03-16 CN CN01806605A patent/CN1424910A/en active Pending
- 2001-03-16 JP JP2001566648A patent/JP2003526664A/en not_active Withdrawn
- 2001-03-16 AU AU2001250873A patent/AU2001250873A1/en not_active Abandoned
- 2001-03-16 CA CA002403062A patent/CA2403062A1/en not_active Abandoned
- 2001-03-16 CZ CZ20023075A patent/CZ20023075A3/en unknown
- 2001-03-16 EP EP01924195A patent/EP1263427A4/en not_active Withdrawn
- 2001-03-16 OA OA1200200289A patent/OA12231A/en unknown
- 2001-03-16 DZ DZ013317A patent/DZ3317A1/fr active
- 2001-03-16 AP APAP/P/2002/002606A patent/AP2002002606A0/en unknown
- 2001-03-16 WO PCT/US2001/008672 patent/WO2001068084A1/en not_active Application Discontinuation
- 2001-03-16 BR BR0108749-5A patent/BR0108749A/en not_active Application Discontinuation
- 2001-03-16 PL PL01366034A patent/PL366034A1/en not_active Application Discontinuation
- 2001-03-16 MX MXPA02009094A patent/MXPA02009094A/en active IP Right Grant
- 2001-03-16 KR KR1020027012102A patent/KR20020091130A/en not_active Application Discontinuation
- 2001-03-16 SK SK1328-2002A patent/SK13282002A3/en unknown
- 2001-03-16 HU HU0300470A patent/HUP0300470A3/en unknown
2002
- 2002-08-20 BG BG107013A patent/BG107013A/en unknown
- 2002-09-12 MA MA26815A patent/MA25659A1/en unknown
- 2002-09-12 NO NO20024367A patent/NO20024367L/en unknown
- 2002-09-12 ZA ZA200207325A patent/ZA200207325B/en unknown

Also Published As

Publication number	Publication date
HUP0300470A2 (en)	2003-06-28
MXPA02009094A (en)	2003-03-12
ZA200207325B (en)	2003-10-17
EA200200981A1 (en)	2003-02-27
KR20020091130A (en)	2002-12-05
NO20024367D0 (en)	2002-09-12
EP1263427A4 (en)	2005-08-24
OA12231A (en)	2003-11-07
AP2002002606A0 (en)	2002-09-30
CN1424910A (en)	2003-06-18
SK13282002A3 (en)	2003-02-04
MA25659A1 (en)	2002-12-31
BR0108749A (en)	2004-06-29
CO5280089A1 (en)	2003-05-30
AU2001250873A1 (en)	2001-09-24
WO2001068084A1 (en)	2001-09-20
JP2003526664A (en)	2003-09-09
EP1263427A1 (en)	2002-12-11
NO20024367L (en)	2002-10-22
DZ3317A1 (en)	2001-09-20
BG107013A (en)	2003-05-30
CA2403062A1 (en)	2001-09-20
AR031098A1 (en)	2003-09-10
CZ20023075A3 (en)	2003-05-14
HUP0300470A3 (en)	2005-05-30

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