PL3504210T3 - 7-podstawione związki sulfonimidoilopurynonowe do leczenia i profilaktyki zakażeń wirusowych - Google Patents
7-podstawione związki sulfonimidoilopurynonowe do leczenia i profilaktyki zakażeń wirusowychInfo
- Publication number
- PL3504210T3 PL3504210T3 PL17758527T PL17758527T PL3504210T3 PL 3504210 T3 PL3504210 T3 PL 3504210T3 PL 17758527 T PL17758527 T PL 17758527T PL 17758527 T PL17758527 T PL 17758527T PL 3504210 T3 PL3504210 T3 PL 3504210T3
- Authority
- PL
- Poland
- Prior art keywords
- prophylaxis
- treatment
- virus infection
- substituted
- compounds
- Prior art date
Links
- -1 7-substituted sulfonimidoylpurinone compounds Chemical class 0.000 title 1
- 238000011321 prophylaxis Methods 0.000 title 1
- 238000011282 treatment Methods 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2016097140 | 2016-08-29 | ||
| CN2017092653 | 2017-07-12 | ||
| PCT/EP2017/071514 WO2018041763A1 (en) | 2016-08-29 | 2017-08-28 | 7-substituted sulfonimidoylpurinone compounds for the treatment and prophylaxis of virus infection |
| EP17758527.0A EP3504210B1 (en) | 2016-08-29 | 2017-08-28 | 7-substituted sulfonimidoylpurinone compounds for the treatment and prophylaxis of virus infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3504210T3 true PL3504210T3 (pl) | 2021-07-05 |
Family
ID=59738346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17758527T PL3504210T3 (pl) | 2016-08-29 | 2017-08-28 | 7-podstawione związki sulfonimidoilopurynonowe do leczenia i profilaktyki zakażeń wirusowych |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US10233184B2 (pl) |
| EP (2) | EP3865482A1 (pl) |
| JP (2) | JP7013467B2 (pl) |
| KR (2) | KR20220147702A (pl) |
| CN (1) | CN109641904B (pl) |
| AU (3) | AU2017320742B2 (pl) |
| BR (1) | BR112019003519A2 (pl) |
| CA (1) | CA3034148A1 (pl) |
| CL (1) | CL2019000512A1 (pl) |
| CO (1) | CO2019000932A2 (pl) |
| CR (1) | CR20190087A (pl) |
| DK (1) | DK3504210T3 (pl) |
| ES (1) | ES2867849T3 (pl) |
| HR (1) | HRP20210621T1 (pl) |
| HU (1) | HUE053944T2 (pl) |
| IL (3) | IL284255B (pl) |
| MA (1) | MA46038B1 (pl) |
| MX (2) | MX2019002129A (pl) |
| MY (1) | MY197408A (pl) |
| PE (1) | PE20190476A1 (pl) |
| PH (1) | PH12019500432A1 (pl) |
| PL (1) | PL3504210T3 (pl) |
| PT (1) | PT3504210T (pl) |
| RS (1) | RS61752B1 (pl) |
| RU (1) | RU2751349C2 (pl) |
| SG (2) | SG11201901633WA (pl) |
| SI (1) | SI3504210T1 (pl) |
| TW (1) | TWI671300B (pl) |
| UA (1) | UA124270C2 (pl) |
| WO (1) | WO2018041763A1 (pl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6738352B2 (ja) * | 2015-05-08 | 2020-08-12 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ウイルス感染の治療及び予防のための新規なスルホンイミドイルプリノン化合物及び誘導体 |
| PL3504210T3 (pl) * | 2016-08-29 | 2021-07-05 | F. Hoffmann-La Roche Ag | 7-podstawione związki sulfonimidoilopurynonowe do leczenia i profilaktyki zakażeń wirusowych |
| CA3034185A1 (en) * | 2016-09-13 | 2018-03-22 | F. Hoffmann-La Roche Ag | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
| CN111699187A (zh) | 2018-02-12 | 2020-09-22 | 豪夫迈·罗氏有限公司 | 用于治疗和预防病毒感染的新的砜化合物和衍生物 |
| EP3758707A1 (en) * | 2018-02-28 | 2021-01-06 | F. Hoffmann-La Roche AG | 7-substituted sulfonimidoylpurinone compounds and derivatives for the treatment and prophylaxis of liver cancer |
| US20200113912A1 (en) | 2018-09-12 | 2020-04-16 | Silverback Therapeutics, Inc. | Methods and Compositions for the Treatment of Disease with Immune Stimulatory Conjugates |
| MX2021009496A (es) | 2019-02-08 | 2021-09-08 | Progeneer Inc | Complejo de colesterol-agonista del receptor 7 u 8 tipo larga distancia, y uso del mismo. |
| AU2020358726A1 (en) | 2019-10-01 | 2022-04-07 | Silverback Therapeutics, Inc. | Combination therapy with immune stimulatory conjugates |
| EP4106819A1 (en) | 2020-02-21 | 2022-12-28 | Silverback Therapeutics, Inc. | Nectin-4 antibody conjugates and uses thereof |
| AU2021231160A1 (en) | 2020-03-02 | 2022-09-22 | Progeneer Inc. | Live-pathogen-mimetic nanoparticles based on pathogen cell wall skeleton, and production method thereof |
| IL299508A (en) | 2020-07-01 | 2023-02-01 | Ars Pharmaceuticals Inc | Name of the invention: antibody conjugates against ASGR1 and their uses |
| US20230355750A1 (en) | 2020-08-04 | 2023-11-09 | Progeneer Inc. | Kinetically acting adjuvant ensemble |
| WO2022031021A1 (ko) | 2020-08-04 | 2022-02-10 | 성균관대학교산학협력단 | 동력학적 제어가 가능한 아주번트를 포함하는 mrna 백신 |
| WO2022031057A1 (ko) | 2020-08-04 | 2022-02-10 | 성균관대학교산학협력단 | 활성화 부위가 일시적으로 비활성화된 톨-유사 수용체 7 또는 8 작용자와 기능성 약물의 결합체 및 그 용도 |
| CN114315861A (zh) * | 2020-09-27 | 2022-04-12 | 上海维申医药有限公司 | 大环tlr7激动剂、其制备方法、药物组合物及其用途 |
| GB202306325D0 (en) | 2023-04-28 | 2023-06-14 | Iksuda Therapeutics Ltd | Antibody-drug conjugate compounds, and methods of use and treatment |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0141927B1 (en) * | 1983-08-18 | 1991-10-30 | Beecham Group Plc | Antiviral guanine derivatives |
| CA2230808C (en) | 1996-07-03 | 2006-08-15 | Japan Energy Corporation | A novel purine derivative |
| AUPO912997A0 (en) | 1997-09-11 | 1997-10-02 | Commonwealth Scientific And Industrial Research Organisation | Antiviral agents |
| AU732361B2 (en) * | 1997-11-28 | 2001-04-26 | Dainippon Sumitomo Pharma Co., Ltd. | Novel heterocyclic compounds |
| JPH11180981A (ja) * | 1997-12-19 | 1999-07-06 | Sumitomo Pharmaceut Co Ltd | 複素環誘導体 |
| TW572758B (en) | 1997-12-22 | 2004-01-21 | Sumitomo Pharma | Type 2 helper T cell-selective immune response inhibitors comprising purine derivatives |
| JP4189048B2 (ja) * | 1997-12-26 | 2008-12-03 | 大日本住友製薬株式会社 | 複素環化合物 |
| WO2004006867A2 (en) | 2002-03-15 | 2004-01-22 | Wayne State University | 2-amino-9-[(2-hydroxymethyl) cyclopropylidenemethyl] purine antiviral agents |
| ES2387388T3 (es) * | 2002-09-27 | 2012-09-21 | Dainippon Sumitomo Pharma Co., Ltd. | Compuesto de adenina y uso del mismo |
| BRPI0611435A2 (pt) | 2005-05-04 | 2010-09-08 | Pfizer Ltd | derivados de 2-amido-6-amino-8-oxopurina, composições farmacêuticas, uso e processo de preparo dos mesmos |
| DE102006053049A1 (de) | 2006-11-10 | 2008-05-15 | Daimler Ag | Staufach mit einer Abdeckeinrichtung |
| ES2541434T3 (es) * | 2007-06-29 | 2015-07-20 | Gilead Sciences, Inc. | Derivados de purina y su uso como moduladores del receptor de tipo Toll 7 |
| CN101239980B (zh) | 2008-02-18 | 2011-06-22 | 靳广毅 | 免疫受体调节剂偶联体前体和偶联体及其应用 |
| JP5600116B2 (ja) * | 2008-12-09 | 2014-10-01 | ギリアード サイエンシーズ， インコーポレイテッド | Ｔｏｌｌ様受容体のモジュレーター |
| EP2491035B1 (en) * | 2009-10-22 | 2017-08-30 | Gilead Sciences, Inc. | Derivatives of purine or deazapurine useful for the treatment of (inter alia) viral infections |
| US20110150836A1 (en) | 2009-12-22 | 2011-06-23 | Gilead Sciences, Inc. | Methods of treating hbv and hcv infection |
| US8501724B1 (en) * | 2012-01-31 | 2013-08-06 | Pharmacyclics, Inc. | Purinone compounds as kinase inhibitors |
| PT3190113T (pt) | 2014-08-15 | 2021-06-17 | Chai Tai Tianqing Pharmaceutical Group Co Ltd | Compostos pirrolopirimidina utilizados como agonistas de tlr7 |
| JP6738352B2 (ja) * | 2015-05-08 | 2020-08-12 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ウイルス感染の治療及び予防のための新規なスルホンイミドイルプリノン化合物及び誘導体 |
| PL3504210T3 (pl) * | 2016-08-29 | 2021-07-05 | F. Hoffmann-La Roche Ag | 7-podstawione związki sulfonimidoilopurynonowe do leczenia i profilaktyki zakażeń wirusowych |
-
2017
- 2017-08-28 PL PL17758527T patent/PL3504210T3/pl unknown
- 2017-08-28 SG SG11201901633WA patent/SG11201901633WA/en unknown
- 2017-08-28 SG SG10202010520SA patent/SG10202010520SA/en unknown
- 2017-08-28 SI SI201730728T patent/SI3504210T1/sl unknown
- 2017-08-28 CA CA3034148A patent/CA3034148A1/en active Pending
- 2017-08-28 PE PE2019000346A patent/PE20190476A1/es unknown
- 2017-08-28 IL IL284255A patent/IL284255B/en unknown
- 2017-08-28 TW TW106129087A patent/TWI671300B/zh active
- 2017-08-28 RS RS20210489A patent/RS61752B1/sr unknown
- 2017-08-28 MA MA46038A patent/MA46038B1/fr unknown
- 2017-08-28 KR KR1020227036198A patent/KR20220147702A/ko not_active Application Discontinuation
- 2017-08-28 EP EP20207475.3A patent/EP3865482A1/en not_active Withdrawn
- 2017-08-28 AU AU2017320742A patent/AU2017320742B2/en active Active
- 2017-08-28 BR BR112019003519-2A patent/BR112019003519A2/pt active IP Right Grant
- 2017-08-28 JP JP2019532184A patent/JP7013467B2/ja active Active
- 2017-08-28 PT PT177585270T patent/PT3504210T/pt unknown
- 2017-08-28 WO PCT/EP2017/071514 patent/WO2018041763A1/en active Application Filing
- 2017-08-28 EP EP17758527.0A patent/EP3504210B1/en active Active
- 2017-08-28 RU RU2019107957A patent/RU2751349C2/ru active
- 2017-08-28 CN CN201780052692.6A patent/CN109641904B/zh active Active
- 2017-08-28 DK DK17758527.0T patent/DK3504210T3/da active
- 2017-08-28 MX MX2019002129A patent/MX2019002129A/es unknown
- 2017-08-28 KR KR1020197008982A patent/KR102459155B1/ko active Application Filing
- 2017-08-28 UA UAA201903059A patent/UA124270C2/uk unknown
- 2017-08-28 HU HUE17758527A patent/HUE053944T2/hu unknown
- 2017-08-28 ES ES17758527T patent/ES2867849T3/es active Active
- 2017-08-28 CR CR20190087A patent/CR20190087A/es unknown
- 2017-08-28 IL IL293475A patent/IL293475B2/en unknown
- 2017-08-28 MY MYPI2019001082A patent/MY197408A/en unknown
- 2017-08-29 US US15/689,136 patent/US10233184B2/en active Active
-
2019
- 2019-01-29 US US16/260,744 patent/US10752630B2/en active Active
- 2019-01-30 CO CONC2019/0000932A patent/CO2019000932A2/es unknown
- 2019-02-07 IL IL264710A patent/IL264710B/en unknown
- 2019-02-21 MX MX2021006902A patent/MX2021006902A/es unknown
- 2019-02-26 CL CL2019000512A patent/CL2019000512A1/es unknown
- 2019-02-27 PH PH12019500432A patent/PH12019500432A1/en unknown
-
2020
- 2020-08-24 US US17/001,572 patent/US20200385387A1/en not_active Abandoned
-
2021
- 2021-04-19 HR HRP20210621TT patent/HRP20210621T1/hr unknown
- 2021-06-24 AU AU2021204303A patent/AU2021204303B2/en active Active
-
2022
- 2022-01-17 JP JP2022004832A patent/JP7214900B2/ja active Active
- 2022-06-30 AU AU2022204697A patent/AU2022204697A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL284255A (en) | 7-substituted sulfonimidylpurinone compounds for the treatment and prevention of viral infection | |
| HK1251554A1 (zh) | 用於治療和預防病毒感染的新的取代的氨基噻唑並嘧啶二酮 | |
| HK1248711A1 (zh) | 用於治療和預防病毒感染的新的取代的氨基噻唑並嘧啶二酮 | |
| HRP20190352T1 (hr) | Novi 6-kondenzirani heteroarildihidropirimidini za liječenje i profilaksu infekcije virusom hepatitisa b | |
| HUS2200053I1 (hu) | HIV vírusfertõzés megelõzõ vagy terápiás kezelésére alkalmas terápiás vegyületek | |
| HK1251221A1 (zh) | 用於治療和預防乙型肝炎病毒感染的新的三環4-吡啶酮-3-甲酸衍生物 | |
| HK1251220A1 (zh) | 用於治療和預防乙型肝炎病毒感染的新的四環4-氧代-吡啶-3-甲酸衍生物 | |
| HK1223931A1 (zh) | 用於治療和預防乙型肝炎病毒感染的新型二氫喹嗪酮類化合物 | |
| IL263972A (en) | Dihydropyranopyrimidines for the treatment of viral infections | |
| IL280769A (en) | New sulfonimidylpurinone compounds and their history for the treatment and prevention of virus infection | |
| HK1252343A1 (zh) | 用於治療病毒感染的組合物和方法 | |
| ZA201900770B (en) | 7-substituted sulfonimidoylpurinone compounds for the treatment and prophylaxis of virus infection | |
| LT3504210T (lt) | Nauji 7 padėtyje pakeisti sulfonimidoilpurinono junginiai, skirti viruso sukeliamos infekcijos gydymui ir profilaktikai | |
| ZA201604784B (en) | Novel 6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection |