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PL2970994T3 - Promotor konstytutywny - Google Patents

Promotor konstytutywny

Info

Publication number
PL2970994T3
PL2970994T3 PL13811203T PL13811203T PL2970994T3 PL 2970994 T3 PL2970994 T3 PL 2970994T3 PL 13811203 T PL13811203 T PL 13811203T PL 13811203 T PL13811203 T PL 13811203T PL 2970994 T3 PL2970994 T3 PL 2970994T3
Authority
PL
Poland
Prior art keywords
constitutive promoter
constitutive
promoter
Prior art date
Application number
PL13811203T
Other languages
English (en)
Inventor
Diethard Mattanovich
Brigitte Gasser
Roland PRIELHOFER
Original Assignee
Lonza Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/835,589 external-priority patent/US9150870B2/en
Application filed by Lonza Ltd filed Critical Lonza Ltd
Publication of PL2970994T3 publication Critical patent/PL2970994T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL13811203T 2013-03-15 2013-12-18 Promotor konstytutywny PL2970994T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP13159527 2013-03-15
US13/835,589 US9150870B2 (en) 2013-03-15 2013-03-15 Constitutive promoter
EP13811203.2A EP2970994B1 (en) 2013-03-15 2013-12-18 Constitutive promoter
PCT/EP2013/077144 WO2014139608A1 (en) 2013-03-15 2013-12-18 Constitutive promoter

Publications (1)

Publication Number Publication Date
PL2970994T3 true PL2970994T3 (pl) 2020-03-31

Family

ID=49841670

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13811203T PL2970994T3 (pl) 2013-03-15 2013-12-18 Promotor konstytutywny

Country Status (15)

Country Link
US (1) US11168117B2 (pl)
EP (2) EP2970994B1 (pl)
JP (2) JP6698352B2 (pl)
KR (1) KR102128959B1 (pl)
CN (1) CN105229154A (pl)
AU (1) AU2013382370B2 (pl)
BR (1) BR112015022558A2 (pl)
CA (1) CA2903568C (pl)
DK (1) DK2970994T3 (pl)
ES (1) ES2751336T3 (pl)
HK (1) HK1213292A1 (pl)
IL (1) IL241340B (pl)
PL (1) PL2970994T3 (pl)
SG (2) SG11201507557UA (pl)
WO (1) WO2014139608A1 (pl)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109219662A (zh) * 2016-03-02 2019-01-15 龙沙有限公司 改进的发酵工艺
JP2021513370A (ja) 2018-02-12 2021-05-27 ロンザ リミテッドLonza Limited 目的タンパク質を産生するための宿主細胞
EP3536784A1 (en) 2018-03-05 2019-09-11 ACIB GmbH Host cell engineered for improved metabolite production
WO2019236452A1 (en) * 2018-06-07 2019-12-12 Basf Se Methods for identifying promoters for protein production in yeast
JP2020146307A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146316A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146302A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146297A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146317A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146303A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146304A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146314A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146318A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146300A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146301A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146299A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146315A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146309A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146311A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146306A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146308A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146298A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146305A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146313A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
JP2020146312A (ja) * 2019-03-14 2020-09-17 株式会社三洋物産 遊技機
AU2020252241B2 (en) 2019-04-01 2024-03-21 Universität Für Bodenkultur Wien Mut- methylotrophic yeast
WO2020200415A1 (en) 2019-04-01 2020-10-08 Lonza Ltd Mut- methylotrophic yeast
WO2020200414A1 (en) 2019-04-01 2020-10-08 Lonza Ltd Protein production in mut-methylotrophic yeast
US20220315936A1 (en) * 2019-07-25 2022-10-06 Council Of Scientific & Industrial Research Recombinant vector for high-expression of proteins in yeasts
EP4127185A1 (en) 2020-04-01 2023-02-08 Lonza Ltd. Helper factors for expressing proteins in yeast
WO2022069613A1 (en) 2020-09-30 2022-04-07 Lonza Ltd Host cells overexpressing translational factors
WO2022130163A1 (en) * 2020-12-14 2022-06-23 Indian Institute Of Science Nucleotide sequence, expression vectors, recombinant yeast cells and applications thereof
EP4291659A1 (en) 2021-02-12 2023-12-20 Boehringer Ingelheim RCV GmbH & Co KG Signal peptides for increased protein secretion
WO2024133538A1 (en) 2022-12-20 2024-06-27 Lonza Ltd Host cells with pat1 knockout for increased specific protein productivity
CN118308361B (zh) * 2024-06-07 2024-09-17 中国人民解放军军事科学院军事医学研究院 表达人血清白蛋白的重组序列、生物材料及其应用与方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU577259B2 (en) 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
US4808537A (en) 1984-10-30 1989-02-28 Phillips Petroleum Company Methanol inducible genes obtained from pichia and methods of use
US4855231A (en) 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
EP0922109A1 (en) 1996-05-21 1999-06-16 Novo Nordisk A/S Novel yeast promoters suitable for expression cloning in yeast and heterologous expression of proteins in yeast
US6730499B1 (en) 1998-07-03 2004-05-04 Research Corporation Technologies, Inc. Promoter for the Pichia pastoris formaldehyde dehydrogenase gene FLD1
US7259255B2 (en) 2003-06-25 2007-08-21 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
AT501955B1 (de) 2005-02-23 2007-08-15 Univ Graz Tech Mutierte aox1-promotoren
KR20070009269A (ko) 2005-07-15 2007-01-18 한국생명공학연구원 재조합단백질 생산용 단백질융합인자 라이브러리 및이로부터 획득된 단백질융합인자
ATE486944T1 (de) 2005-11-16 2010-11-15 Korea Res Inst Of Bioscience Translationselongationsfaktor-promotor aus pichia pastoris und verfahren zur herstellung von rekombinantem protein unter verwendung davon
US8440456B2 (en) * 2009-05-22 2013-05-14 Vib, Vzw Nucleic acids of Pichia pastoris and use thereof for recombinant production of proteins
CN102180954B (zh) * 2011-03-01 2013-04-17 华南理工大学 一种毕赤酵母壁蛋白及其构建的表面展示系统和构建方法
CN102994501B (zh) 2012-10-15 2018-04-27 华南理工大学 具有组成型启动子活性的dna及其应用和巴斯德毕赤酵母表达载体
US20150293076A1 (en) * 2012-10-22 2015-10-15 Bolt Threads, Inc. Cellular Reprogramming for Product Optimization
CN105358694B (zh) * 2013-03-08 2019-06-18 凯克应用生命科学研究生院 来自巴斯德毕赤酵母的酵母启动子

Also Published As

Publication number Publication date
SG10201804002PA (en) 2018-07-30
CN105229154A (zh) 2016-01-06
EP2970994B1 (en) 2019-07-17
SG11201507557UA (en) 2015-10-29
US11168117B2 (en) 2021-11-09
KR20160002763A (ko) 2016-01-08
US20190337998A1 (en) 2019-11-07
KR102128959B1 (ko) 2020-07-02
WO2014139608A1 (en) 2014-09-18
EP3584322A1 (en) 2019-12-25
HK1213292A1 (zh) 2016-06-30
EP2970994A1 (en) 2016-01-20
CA2903568C (en) 2022-07-12
IL241340A0 (en) 2015-11-30
BR112015022558A2 (pt) 2017-10-24
AU2013382370A1 (en) 2015-09-24
DK2970994T3 (da) 2019-10-28
JP2016508742A (ja) 2016-03-24
JP6698352B2 (ja) 2020-05-27
JP2019047804A (ja) 2019-03-28
IL241340B (en) 2022-02-01
CA2903568A1 (en) 2014-09-18
ES2751336T3 (es) 2020-03-31
AU2013382370B2 (en) 2020-01-23

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