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PL2812005T3 - Polihydroksylowane pentacykliczne kwasy triterpenowe jako inhibitory reduktazy HMG-CoA - Google Patents

Polihydroksylowane pentacykliczne kwasy triterpenowe jako inhibitory reduktazy HMG-CoA

Info

Publication number
PL2812005T3
PL2812005T3 PL13723722T PL13723722T PL2812005T3 PL 2812005 T3 PL2812005 T3 PL 2812005T3 PL 13723722 T PL13723722 T PL 13723722T PL 13723722 T PL13723722 T PL 13723722T PL 2812005 T3 PL2812005 T3 PL 2812005T3
Authority
PL
Poland
Prior art keywords
polyhydroxylated
hmg
coa reductase
reductase inhibitors
pentacyclic triterpene
Prior art date
Application number
PL13723722T
Other languages
English (en)
Inventor
Ingo Wöhrle
Jana MOLDENHAUER
Bärbel Köpcke
Thomas KÜPER
Jens Bitzer
Kathrin Reinhardt
Original Assignee
Prairie Berry Europe Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prairie Berry Europe Gmbh filed Critical Prairie Berry Europe Gmbh
Publication of PL2812005T3 publication Critical patent/PL2812005T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/14—Organic oxygen compounds
    • A21D2/16—Fatty acid esters
    • A21D2/165—Triglycerides
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/36—Vegetable material
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/047—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with yeasts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23C11/02—Milk substitutes, e.g. coffee whitener compositions containing at least one non-milk component as source of fats or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23C15/00—Butter; Butter preparations; Making thereof
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    • A23C15/16—Butter having reduced fat content
    • A—HUMAN NECESSITIES
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    • A23L2/385—Concentrates of non-alcoholic beverages
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    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
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    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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PL13723722T 2012-05-16 2013-05-07 Polihydroksylowane pentacykliczne kwasy triterpenowe jako inhibitory reduktazy HMG-CoA PL2812005T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261647617P 2012-05-16 2012-05-16
PCT/EP2013/059513 WO2013171100A1 (en) 2012-05-16 2013-05-07 Polyhydroxylated pentacyclic triterpene acids as hmg-coa reductase inhibitors
EP13723722.8A EP2812005B8 (en) 2012-05-16 2013-05-07 Polyhydroxylated pentacyclic triterpene acids as hmg-coa reductase inhibitors

Publications (1)

Publication Number Publication Date
PL2812005T3 true PL2812005T3 (pl) 2019-01-31

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ID=48468253

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13723722T PL2812005T3 (pl) 2012-05-16 2013-05-07 Polihydroksylowane pentacykliczne kwasy triterpenowe jako inhibitory reduktazy HMG-CoA

Country Status (5)

Country Link
US (1) US10047034B2 (pl)
EP (1) EP2812005B8 (pl)
ES (1) ES2688879T3 (pl)
PL (1) PL2812005T3 (pl)
WO (1) WO2013171100A1 (pl)

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Publication number Priority date Publication date Assignee Title
KR101663809B1 (ko) * 2014-06-02 2016-10-11 광주과학기술원 클로로필 a 또는 페오포르비드 a를 포함하는 피부 상태 개선용 조성물
KR20180012254A (ko) 2015-04-10 2018-02-05 코멧 바이오리파이닝 인코포레이티드 셀룰로스 바이오매스의 처리를 위한 방법 및 조성물 및 이에 의해 생성된 생성물
TWI786090B (zh) * 2017-02-28 2022-12-11 日商明治股份有限公司 含有源自乳發酵成份之蛋白質之液狀營養組成物
IT201700025666A1 (it) * 2017-03-08 2018-09-08 Neilos S R L Composizione per l’uso nel trattamento dell’ipercolesterolemia e nella prevenzione di patologie cardiovascolari.
CN107033017B (zh) * 2017-04-25 2018-11-13 四川大学 一种快速制备高纯度羟基-γ-山椒素的方法
US20180360089A1 (en) * 2017-06-20 2018-12-20 Syed H. Khundmiri Herbal supplement and methods for formulating the same
CN110536609B (zh) * 2017-06-29 2022-08-16 丘比株式会社 酸性水包油型乳化调味料及其制造方法
FR3070010B1 (fr) * 2017-08-02 2020-12-25 Belles Feuilles Procede et systeme pour conditionner une composition d'extraits secs de plantes, et composition d'extraits secs de plantes ainsi mis en oeuvre.
JP7351856B2 (ja) 2018-05-10 2023-09-27 コメット バイオリファイニング インコーポレイテッド グルコース及びヘミセルロースを含む組成物並びにその使用
LU101117B1 (en) 2019-02-07 2020-08-07 Luxembourg Institute Of Science And Tech (List) METHOD FOR PRODUCING A COMPOSITION COMPRISING A 3-O-p-COUMAROYL ESTER OF TORMENTIC ACID FROM A PLANT CELL CULTURE, APPLICATIONS THEREOF AS ANTIPARASITIC AGENT FOR THE TREATMENT OF TRYPANOSOMIASIS
US11744268B2 (en) * 2019-04-24 2023-09-05 George H. Clark High complete protein, chemical free energy enhancement and muscle rejuvenation beverage for refreshment meal replacement and enhanced anti-inflammatory response
EP3756476A1 (en) * 2019-06-24 2020-12-30 Bioacores, S.L. Apple waste extraction process
KR102221265B1 (ko) * 2019-10-10 2021-03-04 한국과학기술연구원 터리풀 추출물을 포함하는 혈중 콜레스테롤 감소 및 죽상동맥경화증 개선용 식품 조성물 및 치료용 약학 조성물
CN110693003A (zh) * 2019-10-23 2020-01-17 华南理工大学 包埋脂溶性维生素的乳液凝胶及其基于脉冲电场的生产方法
WO2021122789A1 (en) * 2019-12-19 2021-06-24 Evonik Operations Gmbh Compositions for use as antioxidant
CN111205993B (zh) * 2020-01-22 2021-11-02 天津大学 生产熊果酸和齐墩果酸的重组酵母菌及其构建方法和应用
IT202000015598A1 (it) 2020-06-29 2021-12-29 Abel Nutraceuticals S R L Estratto dalla resina della pianta protium heptaphyllum, formulazioni comprendenti tale estratto e processo di estrazione idroalcolica a pressione e temperatura controllate
WO2022043407A1 (fr) 2020-08-25 2022-03-03 Laouarem Yousra Compositions destinées au traitement des troubles neurologiques
CN112474032B (zh) * 2020-09-24 2023-12-12 广东省科学院资源综合利用研究所 一种硅锌矿的选矿方法
CN116782779A (zh) * 2021-02-10 2023-09-19 帝斯曼知识产权资产管理有限公司 粉末组合物(i)
CN116723775A (zh) * 2021-02-10 2023-09-08 帝斯曼知识产权资产管理有限公司 粉末组合物(ii)
JP2023141208A (ja) * 2022-03-23 2023-10-05 日清オイリオグループ株式会社 風味付与剤、風味付与剤の製造方法
CN118489901B (zh) * 2024-07-18 2024-11-08 浙江衡美健康科技股份有限公司 纳米超微乳化工艺及其采用该工艺制备的产品

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159585A (en) 1961-04-12 1964-12-01 Nat Starch Chem Corp Method of encapsulating water insoluble oils and product thereof
US3971852A (en) 1973-06-12 1976-07-27 Polak's Frutal Works, Inc. Process of encapsulating an oil and product produced thereby
EP0089082B1 (en) 1982-03-12 1985-07-24 Unilever N.V. Margarine fat blend, and a process for producing said fat blend
US4532145A (en) 1983-12-19 1985-07-30 General Foods Corporation Fixing volatiles in an amorphous substrate and products therefrom
AU664827B2 (en) 1991-05-03 1995-12-07 Raisio Benecol Ltd. A substance for lowering high cholesterol level in serum and a method for preparing the same
US5124162A (en) 1991-11-26 1992-06-23 Kraft General Foods, Inc. Spray-dried fixed flavorants in a carbohydrate substrate and process
GEP20001898B (en) 1995-11-02 2000-01-05 Warner Lambert Co Method and Pharmaceutical Composition for Regulating Lipid Concentration with Mam
FR2785265B1 (fr) 1998-11-02 2000-12-08 Gervais Danone Sa Capsules de produit laitier et leur procede de fabrication
WO2001080870A2 (en) 2000-04-13 2001-11-01 Ocean Spray Cranberries, Inc. Compositions derived from cranberry and grapefruit and therapeutic uses therefor
US20120237626A9 (en) 2000-12-05 2012-09-20 Palu Afa Kehaati Profiles of lipid proteins and inhibiting HMG-CoA reductase
FR2832632B1 (fr) 2001-11-26 2004-04-23 Mane Fils V Capsule a solubilisation et liberation du contenu rapides
EP1325682A1 (en) * 2001-12-11 2003-07-09 Societe Des Produits Nestle S.A. Food or pet food composition containing plant extracts for maintenance of bone health and prevention or treatment of bone diseases
JP2005029570A (ja) 2003-06-16 2005-02-03 Tokiwa Shokubutsu Kagaku Kenkyusho:Kk コロソリン酸の製造方法
US7420059B2 (en) 2003-11-20 2008-09-02 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
US20070014739A1 (en) 2005-07-14 2007-01-18 Eldridge Gary R Compositions and methods for controlling biofilms and bacterial infections
WO2007019883A1 (en) 2005-08-16 2007-02-22 Symrise Gmbh & Co. Kg Chocolate coated spherical filled capsules
CN101137387B (zh) * 2005-10-27 2011-05-25 兆领有限公司 可用于治疗缺血性心脏病的新血管生成/再血管化的药物组合物和方法
WO2007094497A1 (ja) * 2006-02-17 2007-08-23 Use-Techno Corporation メタボリックシンドローム改善剤
KR101062174B1 (ko) * 2008-11-14 2011-09-05 (주)아모레퍼시픽 감잎으로부터 얻은 에이엠피케이를 활성화 시키는 트리터페노이드계 화합물 및 이를 유효성분으로 포함하는 비만 또는 당뇨의 예방과 치료용 조성물
JP5712207B2 (ja) * 2009-06-12 2015-05-07 ジェネレックス ファーマシューティカルズ インコーポレイテッド 脳疾患及び状態の予防及び治療のための組成物及び方法
KR101107147B1 (ko) 2009-08-18 2012-01-31 경희대학교 산학협력단 산딸나무 열매 추출물, 산딸나무 열매 분획물, 이로부터 분리된 트리테르펜계 화합물 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 고콜레스테롤혈증에 기인하는 심혈관 질환의 예방 및 치료용 약학적 조성물
EP2345646A1 (en) 2010-01-14 2011-07-20 InterMed Discovery GmbH Use of tricyclic sesquiterpene lactones in the treatment of obesity and related diseases and non-therapeutic treatable conditions
US20130165396A1 (en) 2010-05-27 2013-06-27 National Research Council Of Canada Apple Skin Extracts for Treating Cardiovascular Disease
CN101849950A (zh) 2010-06-22 2010-10-06 赵全成 救必应酸在制备调血脂的药物中的应用

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