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PL2789617T3 - Method of preparation of Enantiomers of spiro-oxindole compounds - Google Patents

Method of preparation of Enantiomers of spiro-oxindole compounds

Info

Publication number
PL2789617T3
PL2789617T3 PL14000690T PL14000690T PL2789617T3 PL 2789617 T3 PL2789617 T3 PL 2789617T3 PL 14000690 T PL14000690 T PL 14000690T PL 14000690 T PL14000690 T PL 14000690T PL 2789617 T3 PL2789617 T3 PL 2789617T3
Authority
PL
Poland
Prior art keywords
spiro
enantiomers
preparation
oxindole compounds
oxindole
Prior art date
Application number
PL14000690T
Other languages
Polish (pl)
Inventor
Mikhail Chafeev
Jianmin Fu
Jean-Jacques Cadieux
Original Assignee
Xenon Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42416878&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2789617(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenon Pharmaceuticals Inc. filed Critical Xenon Pharmaceuticals Inc.
Publication of PL2789617T3 publication Critical patent/PL2789617T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
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  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL14000690T 2009-06-29 2010-06-28 Method of preparation of Enantiomers of spiro-oxindole compounds PL2789617T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22142409P 2009-06-29 2009-06-29

Publications (1)

Publication Number Publication Date
PL2789617T3 true PL2789617T3 (en) 2017-02-28

Family

ID=42416878

Family Applications (2)

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PL10731662.2T PL2448943T3 (en) 2009-06-29 2010-06-28 Enantiomers of spiro-oxindole compounds and their uses as therapeutic agents
PL14000690T PL2789617T3 (en) 2009-06-29 2010-06-28 Method of preparation of Enantiomers of spiro-oxindole compounds

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Country Status (35)

Country Link
US (4) US8450358B2 (en)
EP (3) EP3156407A1 (en)
JP (3) JP2012532107A (en)
KR (1) KR101751378B1 (en)
CN (2) CN102471347B (en)
AR (1) AR077252A1 (en)
AU (1) AU2010266549B2 (en)
BR (1) BRPI1012129A2 (en)
CA (1) CA2764878C (en)
CL (1) CL2011003335A1 (en)
CO (1) CO6470866A2 (en)
CY (1) CY1117776T1 (en)
DK (1) DK2448943T3 (en)
EC (1) ECSP11011512A (en)
ES (2) ES2600160T3 (en)
HK (2) HK1203192A1 (en)
HR (2) HRP20110946A2 (en)
HU (1) HUE029658T2 (en)
IL (3) IL217285A (en)
MA (1) MA33552B1 (en)
MX (2) MX342298B (en)
MY (1) MY159099A (en)
NZ (1) NZ596903A (en)
PE (2) PE20160216A1 (en)
PH (1) PH12015502323A1 (en)
PL (2) PL2448943T3 (en)
PT (1) PT2448943T (en)
RU (1) RU2535667C2 (en)
SG (1) SG176307A1 (en)
SI (1) SI2448943T1 (en)
SM (1) SMT201600203B (en)
TN (1) TN2011000664A1 (en)
TW (1) TWI465452B (en)
WO (1) WO2011002708A1 (en)
ZA (1) ZA201108960B (en)

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