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PL2307380T3 - Pochodne N’-nitroksyalkilonikotynamidu do leczenia chorób układu sercowo-naczyniowego - Google Patents

Pochodne N’-nitroksyalkilonikotynamidu do leczenia chorób układu sercowo-naczyniowego

Info

Publication number
PL2307380T3
PL2307380T3 PL09772373T PL09772373T PL2307380T3 PL 2307380 T3 PL2307380 T3 PL 2307380T3 PL 09772373 T PL09772373 T PL 09772373T PL 09772373 T PL09772373 T PL 09772373T PL 2307380 T3 PL2307380 T3 PL 2307380T3
Authority
PL
Poland
Prior art keywords
nitroxyalkylnicotinamides
treatment
cardiovascular diseases
cardiovascular
diseases
Prior art date
Application number
PL09772373T
Other languages
English (en)
Inventor
Małgorzata Urbaniak
Jerzy Gębicki
Andrzej Marcinek
Stefan Chłopicki
Jan Adamus
Original Assignee
Univ Jagiellonski
Politechnika Lodzka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Jagiellonski, Politechnika Lodzka filed Critical Univ Jagiellonski
Publication of PL2307380T3 publication Critical patent/PL2307380T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
PL09772373T 2008-07-01 2009-06-26 Pochodne N’-nitroksyalkilonikotynamidu do leczenia chorób układu sercowo-naczyniowego PL2307380T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PL38556108 2008-07-01
PCT/EP2009/058017 WO2010000673A1 (en) 2008-07-01 2009-06-26 N'-nitroxyalkylnicotinamides for the treatment of cardiovascular diseases
EP09772373A EP2307380B1 (en) 2008-07-01 2009-06-26 N'-nitroxyalkylnicotinamides for the treatment of cardiovascular diseases

Publications (1)

Publication Number Publication Date
PL2307380T3 true PL2307380T3 (pl) 2013-01-31

Family

ID=41058686

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09772373T PL2307380T3 (pl) 2008-07-01 2009-06-26 Pochodne N’-nitroksyalkilonikotynamidu do leczenia chorób układu sercowo-naczyniowego

Country Status (5)

Country Link
US (1) US20110082177A1 (pl)
EP (1) EP2307380B1 (pl)
CA (1) CA2764739A1 (pl)
PL (1) PL2307380T3 (pl)
WO (1) WO2010000673A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL238932B1 (pl) * 2017-12-31 2021-10-18 Univ Jagiellonski Pochodne soli pirydyniowych oraz ich zastosowanie
CA3123531A1 (en) * 2019-01-02 2020-07-09 Celagenex Research (India) Pvt. Ltd. Synergistic combinations of nicotinamide and nitrate enriched amaranthus extract for use in treating vascular endothelial disorders
CN116253679B (zh) * 2023-01-12 2023-09-15 北京沃邦医药科技有限公司 一种尼可地尔精制母液回收品的精制方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK145608C (da) * 1976-04-02 1983-07-11 Chugai Pharmaceutical Co Ltd Analogifremgangsmaade til fremstilling af salpetersyreesteren af n-(2-hydroxyethyl)nicotinamid
PL364348A1 (pl) * 2004-01-12 2005-07-25 PHARMENA Sp.z o.o. Zastosowanie czwartorzędowych soli pirydyniowych jako środka naczynioprotekcyjnego

Also Published As

Publication number Publication date
US20110082177A1 (en) 2011-04-07
WO2010000673A1 (en) 2010-01-07
CA2764739A1 (en) 2010-01-07
EP2307380A1 (en) 2011-04-13
EP2307380B1 (en) 2012-10-24

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