US4060082A
(en)
|
1976-08-16 |
1977-11-29 |
Mpl, Inc. |
Dual-ingredient medication dispenser
|
SE8205892D0
(en)
|
1982-10-18 |
1982-10-18 |
Bror Morein |
IMMUNOGENT MEMBRANE PROTEIN COMPLEX, SET FOR PREPARATION AND USE THEREOF
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
US5916588A
(en)
|
1984-04-12 |
1999-06-29 |
The Liposome Company, Inc. |
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
|
US6090406A
(en)
|
1984-04-12 |
2000-07-18 |
The Liposome Company, Inc. |
Potentiation of immune responses with liposomal adjuvants
|
US4680338A
(en)
|
1985-10-17 |
1987-07-14 |
Immunomedics, Inc. |
Bifunctional linker
|
US5011828A
(en)
|
1985-11-15 |
1991-04-30 |
Michael Goodman |
Immunostimulating guanine derivatives, compositions and methods
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
AU627226B2
(en)
|
1988-08-25 |
1992-08-20 |
Liposome Company, Inc., The |
Influenza vaccine and novel adjuvants
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
JPH0832638B2
(en)
|
1989-05-25 |
1996-03-29 |
カイロン コーポレイション |
Adjuvant formulation comprising submicron oil droplet emulsion
|
US4988815A
(en)
|
1989-10-26 |
1991-01-29 |
Riker Laboratories, Inc. |
3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines
|
US5658731A
(en)
|
1990-04-09 |
1997-08-19 |
Europaisches Laboratorium Fur Molekularbiologie |
2'-O-alkylnucleotides as well as polymers which contain such nucleotides
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
ES2186034T3
(en)
|
1991-03-01 |
2003-05-01 |
Minnesota Mining & Mfg |
INTERMEDIATES FOR THE PREPARATION OF 1H-IMIDAZO (4,5-C) QUINOLIN-4-AMINAS 1-SUBSTITUTED, 2-REPLACED.
|
JPH0614756Y2
(en)
|
1991-06-26 |
1994-04-20 |
株式会社アルテ |
Assembled dual chamber syringe
|
US5936076A
(en)
|
1991-08-29 |
1999-08-10 |
Kirin Beer Kabushiki Kaisha |
αgalactosylceramide derivatives
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
MY111880A
(en)
|
1992-03-27 |
2001-02-28 |
Smithkline Beecham Biologicals S A |
Hepatitis vaccines containing 3-0 deacylated monophosphoryl lipid a
|
IL105325A
(en)
|
1992-04-16 |
1996-11-14 |
Minnesota Mining & Mfg |
Immunogen/vaccine adjuvant composition
|
UA40597C2
(en)
|
1992-06-25 |
2001-08-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Vaccine composition, method for treatment of mammals, diseased or receptive to the infection, method for treatment of mammals with cancer, method for production of vaccine composition, composition of adjuvants
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
PL178578B1
(en)
|
1993-03-23 |
2000-05-31 |
Smithkline Beecham Biolog |
Composition of vaccines containing 3-0-deacylated monophosphoryl lipoid a
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
AU681687B2
(en)
|
1993-07-15 |
1997-09-04 |
Minnesota Mining And Manufacturing Company |
Imidazo(4,5-c)pyridin-4-amines
|
US5762939A
(en)
*
|
1993-09-13 |
1998-06-09 |
Mg-Pmc, Llc |
Method for producing influenza hemagglutinin multivalent vaccines using baculovirus
|
AU5543294A
(en)
|
1993-10-29 |
1995-05-22 |
Pharmos Corp. |
Submicron emulsions as vaccine adjuvants
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
US6429199B1
(en)
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US5496284A
(en)
|
1994-09-27 |
1996-03-05 |
Waldenburg; Ottfried |
Dual-chamber syringe & method
|
AUPM873294A0
(en)
|
1994-10-12 |
1994-11-03 |
Csl Limited |
Saponin preparations and use thereof in iscoms
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
GB9503863D0
(en)
|
1995-02-25 |
1995-04-19 |
Smithkline Beecham Biolog |
Vaccine compositions
|
UA56132C2
(en)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Vaccine composition (variants), method for stabilizing qs21 providing resistance against hydrolysis (variants), method for manufacturing vaccine
|
CA2235257A1
(en)
|
1995-10-20 |
1997-04-24 |
Yissum Research Development Company Of The Hebrew University Of Jerusale M |
Influenza vaccine
|
DE19612967A1
(en)
|
1996-04-01 |
1997-10-02 |
Behringwerke Ag |
Process for the propagation of influenza viruses in cell culture, and the influenza viruses obtainable by the process
|
DE19612966B4
(en)
*
|
1996-04-01 |
2009-12-10 |
Novartis Vaccines And Diagnostics Gmbh & Co. Kg |
MDCK cells and methods of propagating influenza viruses
|
WO1998001174A1
(en)
|
1996-07-05 |
1998-01-15 |
Debiotech S.A. |
Dual-chamber syringe for mixing two substances prior to injection
|
CA2283557A1
(en)
|
1997-03-10 |
1998-09-17 |
Heather L. Davis |
Use of nucleic acids containing unmethylated cpg dinucleotide as an adjuvant
|
US6818222B1
(en)
|
1997-03-21 |
2004-11-16 |
Chiron Corporation |
Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
|
TW570803B
(en)
|
1997-04-09 |
2004-01-11 |
Duphar Int Res |
Influenza vaccine
|
US6080725A
(en)
|
1997-05-20 |
2000-06-27 |
Galenica Pharmaceuticals, Inc. |
Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
|
US5971953A
(en)
|
1998-01-09 |
1999-10-26 |
Bachynsky; Nicholas |
Dual chamber syringe apparatus
|
WO1999017820A1
(en)
|
1997-10-03 |
1999-04-15 |
Texas Pharmaceuticals, Inc. |
Improved dual chamber syringe apparatus
|
GB9725084D0
(en)
|
1997-11-28 |
1998-01-28 |
Medeva Europ Ltd |
Vaccine compositions
|
BR9909915A
(en)
|
1998-04-09 |
2000-12-26 |
Smithkline Beecham Biolog |
Adjuvant compositions
|
CN1306438A
(en)
|
1998-05-07 |
2001-08-01 |
科里克萨有限公司 |
Adjuvant compsn. and methods for its use
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
US6110929A
(en)
|
1998-07-28 |
2000-08-29 |
3M Innovative Properties Company |
Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
|
GB9817052D0
(en)
|
1998-08-05 |
1998-09-30 |
Smithkline Beecham Biolog |
Vaccine
|
DE19835749C1
(en)
|
1998-08-07 |
2000-02-03 |
Dieter Perthes |
Ready-to-use syringe for unstable drugs
|
US6544785B1
(en)
|
1998-09-14 |
2003-04-08 |
Mount Sinai School Of Medicine Of New York University |
Helper-free rescue of recombinant negative strand RNA viruses
|
AT408615B
(en)
|
1998-09-15 |
2002-01-25 |
Immuno Ag |
NEW INFLUENCE VIRUS VACCINE COMPOSITION
|
WO2000023105A2
(en)
|
1998-10-16 |
2000-04-27 |
Smithkline Beecham Biologicals S.A. |
Adjuvant systems and vaccines
|
US20030130212A1
(en)
|
1999-01-14 |
2003-07-10 |
Rossignol Daniel P. |
Administration of an anti-endotoxin drug by intravenous infusion
|
US6551600B2
(en)
|
1999-02-01 |
2003-04-22 |
Eisai Co., Ltd. |
Immunological adjuvant compounds compositions and methods of use thereof
|
EP1150918B1
(en)
|
1999-02-03 |
2004-09-15 |
Biosante Pharmaceuticals, Inc. |
Method of manufacturing therapeutic calcium phosphate particles
|
EP1955709B1
(en)
|
1999-03-26 |
2012-03-14 |
Vical Incorporated |
Adjuvant compositions for enhancing immune responses to polynucleotide-based vaccines
|
EP1185615B1
(en)
|
1999-04-06 |
2007-08-01 |
Wisconsin Alumni Research Foundation |
Recombinant influenza viruses for vaccines and gene therapy
|
US6331539B1
(en)
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
DE122007000061I2
(en)
|
1999-07-14 |
2011-07-21 |
Sinai School Medicine |
In vitro reconstitution of segmented negative strand RNA viruses.
|
TR200200777T2
(en)
|
1999-09-24 |
2002-09-23 |
Smithkline Beecham Biologicals S.A. |
At least one non-ionic surfactant adjuvant with polyoxyethylene alkyl ether or ester.
|
TR200200774T2
(en)
|
1999-09-24 |
2002-08-21 |
Smithkline Beecham Biologicals S.A. |
Vaccines.
|
JP4763197B2
(en)
|
1999-09-24 |
2011-08-31 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
New vaccine
|
WO2001022972A2
(en)
|
1999-09-25 |
2001-04-05 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acids
|
GB9923176D0
(en)
|
1999-09-30 |
1999-12-01 |
Smithkline Beecham Biolog |
Novel composition
|
AU3108001A
(en)
|
2000-01-20 |
2001-12-24 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory nucleic acids for inducing a th2 immune response
|
AU2001236042B9
(en)
|
2000-03-03 |
2006-06-29 |
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute |
Cell usable in serum-free culture and suspension culture and process for producing virus for vaccine by using the cell
|
HU229101B1
(en)
|
2000-04-28 |
2013-07-29 |
St Jude Childrens Res Hospital |
Dna transfection system for the generation of infectious influenza virus
|
FR2808803B1
(en)
|
2000-05-11 |
2004-12-10 |
Agronomique Inst Nat Rech |
MODIFIED ES CELLS AND SPECIFIC GENE OF ES CELLS
|
US7407662B2
(en)
*
|
2000-06-29 |
2008-08-05 |
Lipid Sciences, Inc. |
Modified viral particles with immunogenic properties and reduced lipid content
|
US6756383B2
(en)
|
2000-09-01 |
2004-06-29 |
Chiron Corporation |
Heterocyclic derivatives of quinolinone benimidazoles
|
PT1650203E
(en)
|
2000-09-11 |
2008-05-13 |
Novartis Vaccines & Diagnostic |
Process of preparation of benzimidazol-2-yl quinolinone derivatives
|
US7262286B2
(en)
|
2000-09-26 |
2007-08-28 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
|
GB0024089D0
(en)
|
2000-10-02 |
2000-11-15 |
Smithkline Beecham Biolog |
Novel compounds
|
US6664265B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
US6677347B2
(en)
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamido ether substituted imidazoquinolines
|
US6660747B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
UA74852C2
(en)
|
2000-12-08 |
2006-02-15 |
3M Innovative Properties Co |
Urea-substituted imidazoquinoline ethers
|
US6664260B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Heterocyclic ether substituted imidazoquinolines
|
US6664264B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
US6667312B2
(en)
|
2000-12-08 |
2003-12-23 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
US6677348B2
(en)
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Aryl ether substituted imidazoquinolines
|
US6660735B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Urea substituted imidazoquinoline ethers
|
US20040096463A1
(en)
|
2001-02-23 |
2004-05-20 |
Nathalie Garcon |
Novel vaccine
|
PT1361890E
(en)
|
2001-02-23 |
2011-06-07 |
Glaxosmithkline Biolog Sa |
Influenza vaccine formulations for intradermal delivery
|
MXPA03008154A
(en)
|
2001-03-09 |
2004-11-12 |
Id Biomedical Corp Quebec |
A novel proteosome-liposaccharide vaccine adjuvant.
|
MY134424A
(en)
|
2001-05-30 |
2007-12-31 |
Saechsisches Serumwerk |
Stable influenza virus preparations with low or no amount of thiomersal
|
DE10144906B4
(en)
|
2001-09-12 |
2013-11-28 |
Novartis Vaccines And Diagnostics Gmbh |
Process for the large-scale production of vaccines
|
DE10144903A1
(en)
|
2001-09-12 |
2003-03-27 |
Chiron Behring Gmbh & Co |
Replication of virus in cell cultures, useful for preparing vaccines and diagnostic reagents, where replication of cells and virus is simultaneous
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
FR2832423B1
(en)
|
2001-11-22 |
2004-10-08 |
Vivalis |
EXOGENOUS PROTEIN EXPRESSION SYSTEM IN AN AVIAN SYSTEM
|
EP1451203B1
(en)
|
2001-11-27 |
2009-11-11 |
Anadys Pharmaceuticals, Inc. |
3-beta-d-ribofuranosylthiazolo(4,5-delta)pyridimine nucleosides and uses thereof
|
US7321033B2
(en)
|
2001-11-27 |
2008-01-22 |
Anadys Pharmaceuticals, Inc. |
3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
|
US6677349B1
(en)
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
FR2836924B1
(en)
|
2002-03-08 |
2005-01-14 |
Vivalis |
AVIAN CELL LINES USEFUL FOR THE PRODUCTION OF INTEREST SUBSTANCES
|
NZ535985A
(en)
|
2002-03-29 |
2007-04-27 |
Chiron Corp |
Substituted benzazoles and use thereof as RAF kinase inhibitors
|
EP1511746A2
(en)
|
2002-05-29 |
2005-03-09 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
CA2493690C
(en)
|
2002-06-13 |
2011-11-08 |
New York University |
Synthetic c-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases
|
SE0202110D0
(en)
|
2002-07-05 |
2002-07-05 |
Isconova Ab |
Iscom preparation and use thereof
|
KR20050038631A
(en)
|
2002-08-23 |
2005-04-27 |
카이론 코포레이션 |
Pyrrole based inhibitors of glycogen synthase kinase 3
|
AU2003300021A1
(en)
|
2002-12-27 |
2004-07-29 |
Chiron Corporation |
Thiosemicarbazones as anti-virals and immunopotentiators
|
US8193185B2
(en)
|
2003-01-21 |
2012-06-05 |
Novartis Vaccines And Diagnostics, Inc. |
Use of tryptanthrin compounds for immune potentiation
|
GB0301554D0
(en)
|
2003-01-23 |
2003-02-26 |
Molecularnature Ltd |
Immunostimulatory compositions
|
EP1608369B1
(en)
|
2003-03-28 |
2013-06-26 |
Novartis Vaccines and Diagnostics, Inc. |
Use of organic compounds for immunopotentiation
|
EP2581093B1
(en)
*
|
2003-06-16 |
2015-03-18 |
MedImmune, LLC |
Influenza hemagglutinin and neuraminidase variants
|
SE0301998D0
(en)
|
2003-07-07 |
2003-07-07 |
Isconova Ab |
Quil A fraction with low toxicity and use thereof
|
RU2236257C1
(en)
|
2003-09-15 |
2004-09-20 |
Косяков Константин Сергеевич |
Synthetic immunogen for therapy and prophylaxis of addiction with narcotic and psychoactive substances
|
US7771726B2
(en)
|
2003-10-08 |
2010-08-10 |
New York University |
Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases
|
EP1528101A1
(en)
|
2003-11-03 |
2005-05-04 |
ProBioGen AG |
Immortalized avian cell lines for virus production
|
KR101153898B1
(en)
|
2004-03-23 |
2012-06-18 |
니프로 가부시키가이샤 |
Pre-filled syringe
|
US20050222048A1
(en)
|
2004-03-31 |
2005-10-06 |
The Research Foundation Of The City University Of New York |
Novel synthetic C-glycolipids, their synthesis and use to treat infections, cancer and autoimmune diseases
|
UA89631C2
(en)
|
2004-04-05 |
2010-02-25 |
Пфайзер Продактс Инк. |
Vaccine composition
|
WO2005113756A1
(en)
|
2004-05-14 |
2005-12-01 |
Glaxosmithkline Biologicals S.A. |
Method
|
EP1747268A1
(en)
|
2004-05-20 |
2007-01-31 |
ID Biomedical Corporation |
Process for the production of an influenza vaccine
|
CA2571421A1
(en)
|
2004-06-24 |
2006-01-05 |
Nicholas Valiante |
Compounds for immunopotentiation
|
JP2008512443A
(en)
|
2004-09-09 |
2008-04-24 |
カイロン ベーリング ゲーエムベーハー アンド カンパニー |
Reduce potential iatrogenic risk associated with influenza vaccines
|
CN103555670B
(en)
|
2004-12-23 |
2015-08-12 |
米迪缪尼有限公司 |
For the non tumorigenic MDCK cell system of virus multiplication
|
RU2435855C2
(en)
|
2004-12-24 |
2011-12-10 |
Солвей Байолоджикалз Б.В. |
Method for producing replicative influenza virus particles, cell composition (versions), cell culture composition and application thereof
|
EP1676569A1
(en)
*
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Lyophilization of virosomes
|
US7572620B2
(en)
*
|
2005-01-11 |
2009-08-11 |
Wisconsin Alumni Research Foundation |
H3 equine influenza A virus
|
FR2884255B1
(en)
|
2005-04-11 |
2010-11-05 |
Vivalis |
USE OF EBX AVIATION STEM CELL LINES FOR THE PRODUCTION OF INFLUENZA VACCINE
|
US7691368B2
(en)
|
2005-04-15 |
2010-04-06 |
Merial Limited |
Vaccine formulations
|
US8703095B2
(en)
|
2005-07-07 |
2014-04-22 |
Sanofi Pasteur S.A. |
Immuno-adjuvant emulsion
|
CN101365480B
(en)
|
2005-11-01 |
2014-11-05 |
诺华疫苗和诊断有限两合公司 |
Cell-derived viral vaccines with low levels of residual cell DNA by beta-propiolactone treatment
|
DE202006021242U1
(en)
*
|
2005-11-04 |
2014-01-29 |
Novartis Vaccines And Diagnostics S.R.L. |
Free aqueous phase surfactant emulsions as an adjuvant for split flu vaccines
|
US20100047277A1
(en)
*
|
2006-07-13 |
2010-02-25 |
Compans Richard W |
Virosomes, methods of preparation, and immunogenic compositions
|
WO2009029695A1
(en)
*
|
2007-08-28 |
2009-03-05 |
Baxter International Inc. |
Method for producing viral vaccines
|