PL2146991T3 - Pochodne triazolopirydyno-karboksamidów, ich wytwarzanie i zastosowanie terapeutyczne - Google Patents

Pochodne triazolopirydyno-karboksamidów, ich wytwarzanie i zastosowanie terapeutyczne

Info

Publication number: PL2146991T3
Authority: PL; Poland
Prior art keywords: preparation; therapeutic use; carboxamide derivatives; triazolopyridine; triazolopyridine carboxamide
Prior art date: 2007-04-18

Application number

PL08787964T

Other languages

English (en)

Inventor

Christian Hoornaert

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-04-18

Filing date

2008-04-16

Publication date

2011-01-31

2008-04-16 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2011-01-31 Publication of PL2146991T3 publication Critical patent/PL2146991T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Physical Education & Sports Medicine (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Obesity (AREA)
Psychiatry (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Ophthalmology & Optometry (AREA)
Virology (AREA)
Vascular Medicine (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Tropical Medicine & Parasitology (AREA)

PL08787964T 2007-04-18 2008-04-16 Pochodne triazolopirydyno-karboksamidów, ich wytwarzanie i zastosowanie terapeutyczne PL2146991T3 (pl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0702807A FR2915197B1 (fr)	2007-04-18	2007-04-18	Derives de triazolopyridine-carboxamides, leur preparation et leur application therapeutique.
PCT/FR2008/000535 WO2008145842A2 (fr)	2007-04-18	2008-04-16	Dérivés de triazolopyridine-carboxamides, leur préparation et leur application en thérapeutique
EP08787964A EP2146991B1 (fr)	2007-04-18	2008-04-16	Dérivés de triazolopyridine-carboxamides, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number	Publication Date
PL2146991T3 true PL2146991T3 (pl)	2011-01-31

Family

ID=38739381

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08787964T PL2146991T3 (pl)	2007-04-18	2008-04-16	Pochodne triazolopirydyno-karboksamidów, ich wytwarzanie i zastosowanie terapeutyczne

Country Status (26)

Country	Link
US (2)	US7868007B2 (pl)
EP (1)	EP2146991B1 (pl)
JP (1)	JP2010524907A (pl)
KR (1)	KR20090130060A (pl)
CN (1)	CN101657451A (pl)
AR (1)	AR066103A1 (pl)
AT (1)	ATE475661T1 (pl)
AU (1)	AU2008257323A1 (pl)
BR (1)	BRPI0810430A2 (pl)
CA (1)	CA2683933A1 (pl)
CY (1)	CY1111601T1 (pl)
DE (1)	DE602008001981D1 (pl)
DK (1)	DK2146991T3 (pl)
ES (1)	ES2348969T3 (pl)
FR (1)	FR2915197B1 (pl)
HR (1)	HRP20100573T1 (pl)
IL (1)	IL201416A0 (pl)
MX (1)	MX2009011215A (pl)
PL (1)	PL2146991T3 (pl)
PT (1)	PT2146991E (pl)
RS (1)	RS51462B (pl)
RU (1)	RU2009142430A (pl)
SI (1)	SI2146991T1 (pl)
TW (1)	TW200906401A (pl)
UY (1)	UY31036A1 (pl)
WO (1)	WO2008145842A2 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2373315A4 (en) *	2008-11-14	2012-06-27	Scripps Research Inst	METHOD AND COMPOSITION RELATING TO TARGETING MONO-ACYLGLYCEROL LIPASE
EP2382012A2 (en)	2008-12-24	2011-11-02	Bial-Portela & CA, S.A.	Pharmaceutical compounds
TW201103932A (en)	2009-04-22	2011-02-01	Janssen Pharmaceutica Nv	Azetidinyl diamides as monoacylglycerol lipase inhibitors
US8450350B2 (en) *	2010-05-05	2013-05-28	Infinity Pharmaceuticals, Inc.	Triazoles as inhibitors of fatty acid synthase
CA2809991A1 (en)	2010-09-03	2012-03-08	Janssen Pharmaceutica Nv	Di-azetidinyl diamide as monoacylglycerol lipase inhibitors
CN103080103A (zh)	2010-09-27	2013-05-01	詹森药业有限公司	作为单酰甘油脂肪酶抑制剂的氧代哌嗪-氮杂环丁烷酰胺和氧代二氮杂*-氮杂环丁烷酰胺
US8513423B2 (en)	2010-10-22	2013-08-20	Janssen Pharmaceutica, Nv	Piperidin-4-yl-azetidine diamides as monoacylglycerol lipase inhibitors
WO2012054721A1 (en)	2010-10-22	2012-04-26	Janssen Pharmaceutical Nv	Amino-pyrrolidine-azetidine diamides as monoacylglycerol lipase inhibitors
EP2567959B1 (en)	2011-09-12	2014-04-16	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
BR112021002298A2 (pt) *	2018-08-13	2021-05-04	F. Hoffmann-La Roche Ag	compostos heterocíclicos como inibidores da monoacilglicerol lipase
MX2020013719A (es) *	2018-08-13	2021-03-02	Hoffmann La Roche	Nuevos compuestos heterociclicos como inhibidores de monoacilglicerol lipasa.
AU2019349962A1 (en)	2018-09-28	2021-03-18	Janssen Pharmaceutica Nv	Monoacylglycerol lipase modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0100624D0 (en) *	2001-01-10	2001-02-21	Vernalis Res Ltd	Chemical compounds VII
DE10247680B4 (de) *	2002-10-12	2005-09-01	Aventis Pharma Deutschland Gmbh	Neue bicyclische Inhibitoren der Hormon Sensitiven Lipase
DE102004005172A1 (de) *	2004-02-02	2005-08-18	Aventis Pharma Deutschland Gmbh	Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
US7632837B2 (en) *	2005-06-17	2009-12-15	Bristol-Myers Squibb Company	Bicyclic heterocycles as cannabinoid-1 receptor modulators
DE102005049954A1 (de) *	2005-10-19	2007-05-31	Sanofi-Aventis Deutschland Gmbh	Triazolopyridin-derivate als Inhibitoren von Lipasen und Phospholipasen

2007
- 2007-04-18 FR FR0702807A patent/FR2915197B1/fr not_active Expired - Fee Related
2008
- 2008-04-16 AT AT08787964T patent/ATE475661T1/de active
- 2008-04-16 RU RU2009142430/04A patent/RU2009142430A/ru not_active Application Discontinuation
- 2008-04-16 PL PL08787964T patent/PL2146991T3/pl unknown
- 2008-04-16 SI SI200830079T patent/SI2146991T1/sl unknown
- 2008-04-16 WO PCT/FR2008/000535 patent/WO2008145842A2/fr active Application Filing
- 2008-04-16 RS RSP-2010/0434A patent/RS51462B/en unknown
- 2008-04-16 ES ES08787964T patent/ES2348969T3/es active Active
- 2008-04-16 JP JP2010503550A patent/JP2010524907A/ja active Pending
- 2008-04-16 AU AU2008257323A patent/AU2008257323A1/en not_active Abandoned
- 2008-04-16 PT PT08787964T patent/PT2146991E/pt unknown
- 2008-04-16 DK DK08787964.9T patent/DK2146991T3/da active
- 2008-04-16 EP EP08787964A patent/EP2146991B1/fr active Active
- 2008-04-16 CA CA002683933A patent/CA2683933A1/fr not_active Abandoned
- 2008-04-16 CN CN200880012319A patent/CN101657451A/zh active Pending
- 2008-04-16 MX MX2009011215A patent/MX2009011215A/es active IP Right Grant
- 2008-04-16 KR KR1020097021600A patent/KR20090130060A/ko not_active Application Discontinuation
- 2008-04-16 DE DE602008001981T patent/DE602008001981D1/de active Active
- 2008-04-16 BR BRPI0810430-1A2A patent/BRPI0810430A2/pt not_active IP Right Cessation
- 2008-04-17 TW TW097114016A patent/TW200906401A/zh unknown
- 2008-04-18 UY UY31036A patent/UY31036A1/es not_active Application Discontinuation
- 2008-04-18 AR ARP080101597A patent/AR066103A1/es unknown
2009
- 2009-10-06 US US12/573,961 patent/US7868007B2/en not_active Expired - Fee Related
- 2009-10-11 IL IL201416A patent/IL201416A0/en unknown
2010
- 2010-10-05 CY CY20101100884T patent/CY1111601T1/el unknown
- 2010-10-19 HR HR20100573T patent/HRP20100573T1/hr unknown
- 2010-11-30 US US12/956,764 patent/US20110071161A1/en not_active Abandoned

Also Published As

Publication number	Publication date
FR2915197A1 (fr)	2008-10-24
RS51462B (en)	2011-04-30
KR20090130060A (ko)	2009-12-17
US7868007B2 (en)	2011-01-11
US20100035893A1 (en)	2010-02-11
AU2008257323A1 (en)	2008-12-04
UY31036A1 (es)	2008-11-28
DE602008001981D1 (de)	2010-09-09
PT2146991E (pt)	2010-10-04
IL201416A0 (en)	2010-05-31
BRPI0810430A2 (pt)	2014-10-14
HRP20100573T1 (hr)	2010-11-30
CY1111601T1 (el)	2015-10-07
EP2146991B1 (fr)	2010-07-28
ES2348969T3 (es)	2010-12-17
WO2008145842A3 (fr)	2009-01-22
MX2009011215A (es)	2009-11-02
SI2146991T1 (sl)	2010-11-30
JP2010524907A (ja)	2010-07-22
WO2008145842A2 (fr)	2008-12-04
DK2146991T3 (da)	2010-11-22
CN101657451A (zh)	2010-02-24
RU2009142430A (ru)	2011-05-27
ATE475661T1 (de)	2010-08-15
TW200906401A (en)	2009-02-16
FR2915197B1 (fr)	2009-06-12
US20110071161A1 (en)	2011-03-24
CA2683933A1 (fr)	2008-12-04
AR066103A1 (es)	2009-07-22
EP2146991A2 (fr)	2010-01-27

Publication	Publication Date	Title
IL201471A0 (en)	2010-05-31	Triazolopyridine carboxamide derivatives and triazolopyrimidine carboxamide derivatives, preparation thereof and therapeutic use thereof
IL207080A0 (en)	2010-12-30	Azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof
IL207078A0 (en)	2010-12-30	Azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof
IL201450A0 (en)	2010-05-31	Triazolopyridine carboxamide derivatives and triazolopyrimidine carboxamide derivatives, preparation thereof and therapeutic use thereof
SI2146991T1 (sl)	2010-11-30	Derivati triazolopiridin karboksamidov njihova priprava in njihova terapevtska uporaba
IL204663A0 (en)	2010-11-30	Nicotinamide derivatives, preparastion thereof and therapeutic use thereof
SI2069342T1 (sl)	2010-09-30	Derivati aril fenil imidazo a piridinov njihova priprava in njihova terapevtska uporaba
HK1159108A1 (en)	2012-07-27	Pyridino-pyridinone derivatives, preparation thereof, and therapeutic use thereof
IL204814A0 (en)	2010-11-30	Quinazolinedione derivatives, preparation thereof and therapeutic uses thereof
IL219888A0 (en)	2012-07-31	Pyridine-pyridinone derivatives, preparation and therapeutic use thereof
IL207629A0 (en)	2010-12-30	Novel 3-aminoalkyl-1,3-dihydro-2h-indol-2-one derivatives, preparation thereof and therapeutic use thereof
IL190519A0 (en)	2008-11-03	6-heteroarylpyridoindolone derivatives, their preparation and therapeutic use thereof
HK1158632A1 (en)	2012-07-20	Derivatives of 2-oxo-alkyl-1-piperazin-2-one, preparation method thereof and therapeutic use of same 2--1--2-
TWI366566B (en)	2012-06-21	Tricyclic n-heteroarylcarboxamide derivatives, preparation thereof and therapeutic use thereof
HK1139671A1 (en)	2010-09-24	Azabicycloalkane derivatives, preparation thereof and use thereof in therapy
SI2106401T1 (sl)	2012-07-31	Derivati pirolopiridin karboksamidov njihova priprava in njihova terapevtska uporaba
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