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PL1943243T3 - Inhibitory kinazy - Google Patents

Inhibitory kinazy

Info

Publication number
PL1943243T3
PL1943243T3 PL06826650T PL06826650T PL1943243T3 PL 1943243 T3 PL1943243 T3 PL 1943243T3 PL 06826650 T PL06826650 T PL 06826650T PL 06826650 T PL06826650 T PL 06826650T PL 1943243 T3 PL1943243 T3 PL 1943243T3
Authority
PL
Poland
Prior art keywords
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
PL06826650T
Other languages
English (en)
Inventor
Jolie Anne Bastian
De Blas Jesus Andres Blas
Dios Alfonso De
Kevin John Hudziak
Tiechao Li
DE URALDE-GARMENDIA Beatriz LÓPEZ
Mary Margaret Mader
Michael Ray Myers
Mark Andrew Pobanz
Chuan Shih
Boyu Zhong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43298635&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1943243(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL1943243T3 publication Critical patent/PL1943243T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL06826650T 2005-10-28 2006-10-25 Inhibitory kinazy PL1943243T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73160405P 2005-10-28 2005-10-28
EP06380151 2006-06-02
US82196306P 2006-08-10 2006-08-10
EP06826650A EP1943243B1 (en) 2005-10-28 2006-10-25 Kinase inhibitors
PCT/US2006/041644 WO2007053394A1 (en) 2005-10-28 2006-10-25 Kinase inhibitors

Publications (1)

Publication Number Publication Date
PL1943243T3 true PL1943243T3 (pl) 2011-05-31

Family

ID=43298635

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06826650T PL1943243T3 (pl) 2005-10-28 2006-10-25 Inhibitory kinazy

Country Status (19)

Country Link
US (1) US7652015B2 (pl)
EP (1) EP1943243B1 (pl)
KR (1) KR101004156B1 (pl)
AR (1) AR056582A1 (pl)
AT (1) ATE493403T1 (pl)
AU (1) AU2006309044B2 (pl)
BR (1) BRPI0616901A2 (pl)
CA (1) CA2627673A1 (pl)
DK (1) DK1943243T3 (pl)
DO (1) DOP2006000234A (pl)
EA (1) EA015189B1 (pl)
PE (1) PE20070795A1 (pl)
PL (1) PL1943243T3 (pl)
PT (1) PT1943243E (pl)
RS (1) RS51949B (pl)
SI (1) SI1943243T1 (pl)
TN (1) TNSN08191A1 (pl)
TW (1) TWI325423B (pl)
WO (1) WO2007053394A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0905955D0 (en) 2009-04-06 2009-05-20 Respivert Ltd Novel compounds
WO2011124930A1 (en) 2010-04-08 2011-10-13 Respivert Limited P38 map kinase inhibitors
WO2011158044A2 (en) 2010-06-17 2011-12-22 Respivert Limited Respiratory formulations and compounds for use therein
US9029378B2 (en) 2011-07-26 2015-05-12 Gruenenthal Gmbh Substituted bicyclic aromatic carboxamide and urea compounds as vanilloid receptor ligands
US20150225373A1 (en) 2012-08-29 2015-08-13 Respivert Limited Kinase inhibitors
US9783556B2 (en) 2012-08-29 2017-10-10 Respivert Limited Kinase inhibitors
WO2014033446A1 (en) 2012-08-29 2014-03-06 Respivert Limited Kinase inhibitors
US9732063B2 (en) 2012-11-16 2017-08-15 Respivert Limited Kinase inhibitors
EP2981534B1 (en) 2013-04-02 2017-07-19 Topivert Pharma Limited Kinase inhibitors based upon n-alkyl pyrazoles
ES2856902T3 (es) 2013-04-02 2021-09-28 Oxular Acquisitions Ltd Derivados de urea útiles como inhibidores de quinasa
CN106029651A (zh) 2013-12-20 2016-10-12 瑞斯比维特有限公司 用作激酶抑制剂的脲衍生物
PL3113772T3 (pl) 2014-03-07 2021-04-06 Biocryst Pharmaceuticals, Inc. Pirazole podstawiane trifluorometylem jako inhibitory ludzkiej kalikreiny osoczowej
MA40775A (fr) 2014-10-01 2017-08-08 Respivert Ltd Dérivé d'acide 4-(4-(4-phényluréido-naphtalén -1-yl) oxy-pyridin-2-yl) amino-benzoïque utilisé en tant qu'inhibiteur de la kinase p38
CN109071505B (zh) 2016-04-06 2021-11-16 奥苏拉收购有限公司 激酶抑制剂
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD
KR20200066655A (ko) 2017-10-05 2020-06-10 풀크럼 쎄러퓨틱스, 인코포레이티드 DUX4의 발현을 저감시키기 위한 p38 저해제의 용도
DK3700902T3 (en) 2017-10-27 2023-05-22 Boehringer Ingelheim Int Inhibitorer af trpc6
AU2021324376A1 (en) 2020-08-13 2023-02-02 Boehringer Ingelheim International Gmbh Treatment of cognitive impairement associated with schizophrenia

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001526222A (ja) * 1997-12-22 2001-12-18 バイエル コーポレイション アリールおよびヘテロアリール置換複素環尿素を使用するp38キナーゼ活性の阻害
ATE400567T1 (de) * 2004-06-23 2008-07-15 Lilly Co Eli Kinaseinhibitoren

Also Published As

Publication number Publication date
US20080269244A1 (en) 2008-10-30
PT1943243E (pt) 2011-01-11
KR101004156B1 (ko) 2010-12-27
EP1943243A1 (en) 2008-07-16
AU2006309044A1 (en) 2007-05-10
US7652015B2 (en) 2010-01-26
EP1943243B1 (en) 2010-12-29
TNSN08191A1 (en) 2009-10-30
DOP2006000234A (es) 2007-05-31
AU2006309044B2 (en) 2011-10-13
CA2627673A1 (en) 2007-05-10
PE20070795A1 (es) 2007-08-24
EA015189B1 (ru) 2011-06-30
DK1943243T3 (da) 2011-03-07
SI1943243T1 (sl) 2011-04-29
WO2007053394A1 (en) 2007-05-10
TWI325423B (en) 2010-06-01
EA200801199A1 (ru) 2008-08-29
TW200800184A (en) 2008-01-01
ATE493403T1 (de) 2011-01-15
AR056582A1 (es) 2007-10-10
KR20080053394A (ko) 2008-06-12
RS51949B (en) 2012-02-29
BRPI0616901A2 (pt) 2011-07-05

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