PL1846412T3 - Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny - Google Patents
Sposób wytwarzania 7-etylo-10-hydroksykamptotecynyInfo
- Publication number
- PL1846412T3 PL1846412T3 PL06708893T PL06708893T PL1846412T3 PL 1846412 T3 PL1846412 T3 PL 1846412T3 PL 06708893 T PL06708893 T PL 06708893T PL 06708893 T PL06708893 T PL 06708893T PL 1846412 T3 PL1846412 T3 PL 1846412T3
- Authority
- PL
- Poland
- Prior art keywords
- ethyl
- manufacturing
- hydroxy camptothecin
- hydroxy
- temperature
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65017505P | 2005-02-07 | 2005-02-07 | |
| EP06708893A EP1846412B1 (en) | 2005-02-07 | 2006-02-06 | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
| PCT/FI2006/000034 WO2006082279A1 (en) | 2005-02-07 | 2006-02-06 | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1846412T3 true PL1846412T3 (pl) | 2010-03-31 |
Family
ID=36588759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06708893T PL1846412T3 (pl) | 2005-02-07 | 2006-02-06 | Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7910737B2 (pl) |
| EP (1) | EP1846412B1 (pl) |
| JP (1) | JP5133705B2 (pl) |
| AT (1) | ATE446299T1 (pl) |
| CA (1) | CA2591081C (pl) |
| DE (1) | DE602006009901D1 (pl) |
| ES (1) | ES2333462T3 (pl) |
| PL (1) | PL1846412T3 (pl) |
| WO (1) | WO2006082279A1 (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006082279A1 (en) | 2005-02-07 | 2006-08-10 | Fermion Oy | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
| PL1846371T3 (pl) * | 2005-02-08 | 2014-01-31 | Fermion Oy | Sposób otrzymywania chlorku [1,4']-bipiperydynylo-1'-karbonylu lub jego chlorowodorku |
| ES2437573T3 (es) * | 2005-02-08 | 2014-01-13 | Fermion Oy | Procedimiento para la preparación de hidrocloruro de irinotecan |
| TWI375678B (en) | 2005-06-09 | 2012-11-01 | Yakult Honsha Kk | A method of preparation of a tricyclic ketone |
| EP2082741A1 (en) * | 2005-09-20 | 2009-07-29 | Scinopharm Singapore Pte, Ltd. | Novel crystal form of irinotecan hydrochloride |
| JP5860213B2 (ja) * | 2007-06-25 | 2016-02-16 | シノファーム タイワン, リミテッドScinopharm Taiwan, Ltd. | ７−エチル−１０−ヒドロキシカンプトテシンの結晶多形 |
| WO2012032531A1 (en) * | 2010-09-06 | 2012-03-15 | Avra Laboratories Pvt. Ltd. | Process for the manufacture of irinotecan hydrochloride by total synthesis |
| KR101327720B1 (ko) * | 2013-02-15 | 2013-11-11 | 제일약품주식회사 | 이리노테칸의 제조방법 |
| EA032135B1 (ru) * | 2014-10-22 | 2019-04-30 | Вивэситас Онколоджи Инк. | Способы и системы для синтеза аналогов камптотецина |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US103309A (en) * | 1870-05-24 | Improvement in machines for burring wool | ||
| US182990A (en) * | 1876-10-10 | Improvement in corner-finish for rooms | ||
| US4473692A (en) | 1981-09-04 | 1984-09-25 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
| JPS6019790A (ja) | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| US5053512A (en) | 1987-04-14 | 1991-10-01 | Research Triangle Institute | Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives |
| US4894456A (en) | 1987-03-31 | 1990-01-16 | Research Triangle Institute | Synthesis of camptothecin and analogs thereof |
| TW438775B (en) | 1995-04-07 | 2001-06-07 | Pharmacia & Upjohn Co Llc | Novel intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds |
| SK1732001A3 (en) | 1998-08-05 | 2001-06-11 | Aventis Pharma Sa | Use of camptothecin derivatives, with reduced gastrointestinal toxicity |
| TWI245768B (en) | 2001-02-21 | 2005-12-21 | Yakult Honsha Kk | Process for synthesizing camptothecin related compound(s) |
| KR20040091083A (ko) | 2002-03-01 | 2004-10-27 | 파마시아 이탈리아 에스.피.에이. | 이리노테칸 히드로클로라이드의 결정성 다형체 |
| EP1501799A1 (en) | 2002-04-17 | 2005-02-02 | Pharmacia Corporation | Compounds useful in preparing camptothecin derivatives |
| US20050267141A1 (en) | 2004-05-28 | 2005-12-01 | Phytogen Life Sciences Inc. | Process to prepare camptothecin derivatives |
| EP1791846A1 (en) | 2004-08-09 | 2007-06-06 | Shilpa Medicare Limited | An improved process for the preparation of irinotecan hydrochloride trihydrate |
| WO2006082279A1 (en) | 2005-02-07 | 2006-08-10 | Fermion Oy | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
-
2006
- 2006-02-06 WO PCT/FI2006/000034 patent/WO2006082279A1/en active Application Filing
- 2006-02-06 JP JP2007553634A patent/JP5133705B2/ja not_active Expired - Fee Related
- 2006-02-06 US US11/883,576 patent/US7910737B2/en active Active
- 2006-02-06 AT AT06708893T patent/ATE446299T1/de not_active IP Right Cessation
- 2006-02-06 EP EP06708893A patent/EP1846412B1/en not_active Not-in-force
- 2006-02-06 CA CA2591081A patent/CA2591081C/en not_active Expired - Fee Related
- 2006-02-06 DE DE602006009901T patent/DE602006009901D1/de active Active
- 2006-02-06 ES ES06708893T patent/ES2333462T3/es active Active
- 2006-02-06 PL PL06708893T patent/PL1846412T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2591081A1 (en) | 2006-08-10 |
| EP1846412B1 (en) | 2009-10-21 |
| US20080103309A1 (en) | 2008-05-01 |
| JP2008529993A (ja) | 2008-08-07 |
| DE602006009901D1 (de) | 2009-12-03 |
| WO2006082279A1 (en) | 2006-08-10 |
| CA2591081C (en) | 2014-10-28 |
| ATE446299T1 (de) | 2009-11-15 |
| US7910737B2 (en) | 2011-03-22 |
| ES2333462T3 (es) | 2010-02-22 |
| JP5133705B2 (ja) | 2013-01-30 |
| EP1846412A1 (en) | 2007-10-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL1846412T3 (pl) | Sposób wytwarzania 7-etylo-10-hydroksykamptotecyny | |
| PL378065A1 (pl) | Podstawione związki N-aryloheterocykliczne, sposób ich wytwarzania oraz ich zastosowanie jako środków leczniczych | |
| IL184524A0 (en) | Substituted pyrazolo-pyridines, compositions containing them, method for the production thereof, and their use | |
| IL173204A0 (en) | Novel cyanopyrrolidides, methods for the production thereof, and use of the same as medicaments | |
| IL186523A0 (en) | Substituted pyrrolo-pyridines, composition containing them, method for their producing and use thereof | |
| IL179758A (en) | Substituted tetrahydro-2h-isoquinolin-1-one derivatives, method for the production thereof and use of the same as medicaments | |
| IL180874A0 (en) | Substituted, bicyclic 8-pyrrolidinoxanthines, method for the production thereof and their use as medicaments | |
| IL181012A0 (en) | Substituted 8-aminoalkoxi-xanthines, method for the production thereof and use thereof as medicaments | |
| PT1928882E (pt) | (s)-n-metilnaltrexona, processo para a sua síntese e sua utilização farmacêutica | |
| PL1740156T3 (pl) | Sposób wytwarzania zabezpieczonej przed nadużyciem, stałej postaci aplikacyjnej | |
| DK1628547T3 (da) | Oralt snusprodukt og fremgangsmåde til fremstilling deraf | |
| IL185253A (en) | Cytoquenols are preserved in spirocetal, a process for their preparation, preparations containing them and methods for their use in the control of pests | |
| HK1124321A1 (en) | Substituted 4-phenyltetrahydroisoquinolines, method of producing them, their use as medicament, and also medicament containing them | |
| WO2007000325A3 (de) | Substituierte 1-oxa-3,8-diazaspiro[4.5]-decan-2-on-verbindungen und deren verwendung zur herstellung von arzneimitteln | |
| IL176420A0 (en) | Process for the manufacture of 2,3-dichloropyridine | |
| WO2007059008A3 (en) | N-substituted indenoisoquinolines and syntheses thereof | |
| MX2007002470A (es) | Fenilaminotiazoles sustituidos y su uso. | |
| IL184314A0 (en) | Substituted 4-phenyltetrahydroisoquinolines, methods for producing them, their use as drug, and drug containing them | |
| NO20073839L (no) | Kinolinderivat, fremgangsmate for fremstilling og anvendelse av dette, og legemiddel inneholdende dette | |
| ZA200607872B (en) | Novel beta agonists, method for producing the same and their use as drugs | |
| NO20072473L (no) | Fremgangsmate for fremstilling av kinolinforbindelser og oppnadde produkter | |
| WO2006009765A3 (en) | Methods for the identification and use of compounds suitable for the treatment of drug resistant cancer cells | |
| PL2059503T3 (pl) | Pochodne aminopirazolu, sposób ich wytwarzania oraz kompozycja do zapobiegania lub leczenia chorób niedokrwiennych zawierająca takie pochodne | |
| TW200517144A (en) | Flavouring-containing pharmaceutical formulations with improved pharmaceutical properties | |
| WO2006122777A3 (de) | Verwendung von 2,5-disubstituierten thiazol-4-on-derivaten in arzneimitteln |