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PL1619185T3 - Pochodna 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepiny lub jej sól - Google Patents

Pochodna 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepiny lub jej sól

Info

Publication number
PL1619185T3
PL1619185T3 PL04729502T PL04729502T PL1619185T3 PL 1619185 T3 PL1619185 T3 PL 1619185T3 PL 04729502 T PL04729502 T PL 04729502T PL 04729502 T PL04729502 T PL 04729502T PL 1619185 T3 PL1619185 T3 PL 1619185T3
Authority
PL
Poland
Prior art keywords
difluoro
tetrahydro
salt
benzazepine derivative
benzazepine
Prior art date
Application number
PL04729502T
Other languages
English (en)
Inventor
Hiroyuki Koshio
Issei Tsukamoto
Akio Kakefuda
Seijiro Akamatsu
Chikashi Saitoh
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of PL1619185T3 publication Critical patent/PL1619185T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL04729502T 2003-04-28 2004-04-26 Pochodna 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepiny lub jej sól PL1619185T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2003123032 2003-04-28
JP2003401126 2003-12-01
EP04729502A EP1619185B1 (en) 2003-04-28 2004-04-26 4,4-difluoro-1,2,3,4-tetrahydro-5h-1-benzazepine derivative or salt thereof
PCT/JP2004/005998 WO2004096775A1 (ja) 2003-04-28 2004-04-26 4,4-ジフルオロ-1,2,3,4-テトラヒドロ-5h-1-ベンゾアゼピン誘導体又はその塩

Publications (1)

Publication Number Publication Date
PL1619185T3 true PL1619185T3 (pl) 2011-12-30

Family

ID=33422056

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04729502T PL1619185T3 (pl) 2003-04-28 2004-04-26 Pochodna 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepiny lub jej sól

Country Status (17)

Country Link
US (2) US7183271B2 (pl)
EP (1) EP1619185B1 (pl)
KR (1) KR100882154B1 (pl)
AT (1) ATE512951T1 (pl)
AU (1) AU2004234258B2 (pl)
BR (1) BRPI0409718A (pl)
CA (1) CA2521492C (pl)
DK (1) DK1619185T3 (pl)
IL (1) IL171332A (pl)
MX (1) MXPA05011521A (pl)
NO (1) NO333505B1 (pl)
NZ (1) NZ542815A (pl)
PL (1) PL1619185T3 (pl)
PT (1) PT1619185E (pl)
RU (1) RU2326868C2 (pl)
SI (1) SI1619185T1 (pl)
WO (1) WO2004096775A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
AU2004234258B2 (en) 2003-04-28 2009-04-09 Tacurion 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof
EP1908753B1 (en) 2005-07-22 2014-12-17 Mochida Pharmaceutical Co., Ltd. Novel heterocyclidene acetamide derivative
AU2008283929B2 (en) 2007-08-06 2013-10-10 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
PT3225250T (pt) * 2008-05-21 2019-10-15 Ferring Bv Desmopressina orodispersivel para aumentar o periodo inicial de sono não perturbado pela nocturia
RS56804B1 (sr) 2012-06-11 2018-04-30 Tacurion Postupak za proizvodnju jedinjenja 4,4,7-trifluoro-1,2,3,4-tetrahidro-5h-1-benzazepina i intermedijer za njegovu sintezu
KR20190026902A (ko) 2016-07-14 2019-03-13 화이자 인코포레이티드 바닌-1 효소의 억제제로서의 신규 피리미딘 카르복스아미드

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL182011B1 (en) * 1993-08-26 2001-10-31 Yamanouchi Pharma Co Ltd Benzazepine derivative, pharmaceutic composition and intermediate compounds
JPH11349570A (ja) 1994-06-15 1999-12-21 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環誘導体
PT1221440E (pt) 1994-06-15 2007-07-20 Otsuka Pharma Co Ltd Derivados benzo-heterocíclicos úteis como moduladores da vasopressina ou oxitocina
JP3215910B2 (ja) * 1994-06-15 2001-10-09 大塚製薬株式会社 ベンゾヘテロ環誘導体
TW359669B (en) 1995-12-15 1999-06-01 Otsuka Pharma Co Ltd Benzazepine derivatives
JPH09221476A (ja) 1995-12-15 1997-08-26 Otsuka Pharmaceut Co Ltd 医薬組成物
JPH09221475A (ja) 1996-02-13 1997-08-26 Yamanouchi Pharmaceut Co Ltd 新規なオキシム誘導体
AR011913A1 (es) 1997-03-06 2000-09-13 Yamano Masaki Derivados de 4,4-difluoro-2,3,4,5-tetrahidro-1h-1-benzoazepina y composiciones farmaceuticas de los mismos.
JP2926335B2 (ja) 1997-06-13 1999-07-28 大塚製薬株式会社 医薬組成物
SI1000062T1 (en) 1997-07-30 2004-12-31 Wyeth Tricyclic vasopressin agonists
DE69826677T2 (de) 1997-07-30 2005-02-10 Wyeth Trizyclische Vasopressin-Agonisten
US6547395B1 (en) 1998-02-06 2003-04-15 Wavefront Sciences, Inc. Methods of measuring moving objects and reducing exposure during wavefront measurements
JP2002536374A (ja) 1999-02-04 2002-10-29 ワイス 三環系ピリジンn−オキシドバソプレシンアゴニスト
GB0000079D0 (en) 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
JP4075064B2 (ja) 2001-11-16 2008-04-16 アステラス製薬株式会社 4,4−ジフルオロ−1,2,3,4−テトラヒドロ−5h−1−ベンゾアゼピン誘導体又はその塩
AU2004234258B2 (en) 2003-04-28 2009-04-09 Tacurion 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine derivative or salt thereof

Also Published As

Publication number Publication date
KR100882154B1 (ko) 2009-02-06
KR20060007402A (ko) 2006-01-24
US20070167429A1 (en) 2007-07-19
ATE512951T1 (de) 2011-07-15
AU2004234258B2 (en) 2009-04-09
EP1619185B1 (en) 2011-06-15
WO2004096775A1 (ja) 2004-11-11
CA2521492C (en) 2010-09-21
US20060122170A1 (en) 2006-06-08
SI1619185T1 (sl) 2011-09-30
DK1619185T3 (da) 2011-07-18
NO20055602L (no) 2006-01-24
US7807664B2 (en) 2010-10-05
NZ542815A (en) 2009-01-31
RU2326868C2 (ru) 2008-06-20
IL171332A (en) 2011-03-31
EP1619185A4 (en) 2008-07-23
NO333505B1 (no) 2013-06-24
CA2521492A1 (en) 2004-11-11
MXPA05011521A (es) 2006-01-23
EP1619185A1 (en) 2006-01-25
NO20055602D0 (no) 2005-11-25
PT1619185E (pt) 2011-08-25
RU2005136863A (ru) 2006-04-20
BRPI0409718A (pt) 2006-05-02
AU2004234258A1 (en) 2004-11-11
US7183271B2 (en) 2007-02-27

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