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PL1687401T3 - Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek - Google Patents

Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek

Info

Publication number
PL1687401T3
PL1687401T3 PL04795276T PL04795276T PL1687401T3 PL 1687401 T3 PL1687401 T3 PL 1687401T3 PL 04795276 T PL04795276 T PL 04795276T PL 04795276 T PL04795276 T PL 04795276T PL 1687401 T3 PL1687401 T3 PL 1687401T3
Authority
PL
Poland
Prior art keywords
proteins
site
amino acids
redox active
active amino
Prior art date
Application number
PL04795276T
Other languages
English (en)
Inventor
Lital Alfonta
Peter G Schultz
Zhiwen Zhang
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of PL1687401T3 publication Critical patent/PL1687401T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL04795276T 2003-10-14 2004-10-13 Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek PL1687401T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51153203P 2003-10-14 2003-10-14
EP04795276A EP1687401B1 (en) 2003-10-14 2004-10-13 Site-specific incorporation of redox active amino acids into proteins
PCT/US2004/034089 WO2005038002A2 (en) 2003-10-14 2004-10-13 Site-specific incorporation of redox active amino acids into proteins

Publications (1)

Publication Number Publication Date
PL1687401T3 true PL1687401T3 (pl) 2013-04-30

Family

ID=34465242

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04795276T PL1687401T3 (pl) 2003-10-14 2004-10-13 Specyficzne względem miejsca włączenie aminokwasów redoks aktywnych do białek

Country Status (14)

Country Link
US (5) US8008041B2 (pl)
EP (1) EP1687401B1 (pl)
JP (1) JP5657850B2 (pl)
CN (2) CN101532046A (pl)
AU (1) AU2004282577B2 (pl)
BR (1) BRPI0415308A (pl)
CA (1) CA2541166A1 (pl)
DK (1) DK1687401T3 (pl)
ES (1) ES2396712T3 (pl)
IL (3) IL174947A (pl)
MX (1) MXPA06004087A (pl)
PL (1) PL1687401T3 (pl)
PT (1) PT1687401E (pl)
WO (1) WO2005038002A2 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1456360B1 (en) * 2001-04-19 2015-06-03 The Scripps Research Institute Methods and composition for the production of orthoganal trna-aminoacyltrna synthetase pairs
WO2004035605A2 (en) * 2002-10-16 2004-04-29 The Scripps Research Institute Glycoprotein synthesis
CN101223272B (zh) 2003-04-17 2013-04-03 斯克利普斯研究院 扩展真核生物遗传密码
CN102618605B (zh) 2003-06-18 2015-09-02 斯克利普斯研究院 非天然活性氨基酸遗传密码增加
PT1666604E (pt) * 2003-07-07 2008-05-19 Scripps Research Inst Composições de pares ortogonais de lisil-arnt e aminoacil-arnt-sintetase e suas utilizações
US7399619B2 (en) * 2004-05-25 2008-07-15 The Scripps Research Institute Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for structure determination
DE102004031258A1 (de) * 2004-06-29 2006-02-09 Jennissen, Herbert P., Prof. Dr. Proteinhybride mit polyhydroxyaromatischen Aminosäure-Epitopen
WO2006036779A2 (en) * 2004-09-22 2006-04-06 The Scripps Research Institute Site-specific labeling of proteins for nmr studies
EP2383340B1 (en) 2004-10-27 2014-07-16 The Scripps Research Institute Orthogonal translation components for the in vivo incorporation of unnatural amino acids
US8367588B2 (en) * 2005-10-12 2013-02-05 The Scripps Research Institute Selective posttranslational modification of phage-displayed polypeptides
US7776535B2 (en) * 2006-02-06 2010-08-17 Franklin And Marshall College Site-specific incorporation of fluorinated amino acids into proteins
CA2638763A1 (en) * 2006-03-09 2007-09-13 The Scripps Research Institute System for the expression of orthogonal translation components in eubacterial host cells
MX2008011669A (es) * 2006-03-16 2008-09-22 Scripps Research Inst Expresion programada geneticamente de proteinas que contienen el aminoacido no natural fenilselenocisteina.
JP2009538136A (ja) * 2006-05-23 2009-11-05 ザ スクリップス リサーチ インスティテュート 遺伝的にコードされた蛍光クマリンアミノ酸
US8114652B2 (en) 2006-09-21 2012-02-14 The Scripps Research Institute Genetically programmed expression of selectively sulfated proteins in eubacteria
CA2665678A1 (en) 2006-10-18 2008-06-19 The Scripps Research Institute Genetic incorporation of unnatural amino acids into proteins in mammalian cells
WO2008137452A1 (en) * 2007-05-04 2008-11-13 Kenergy Royalty Company, Llc Implantable high efficiency digital stimulation device
EP2217707B1 (en) * 2007-10-25 2014-10-15 The Scripps Research Institute Genetic incorporation of 3-aminotyrosine into reductases
US20090148887A1 (en) * 2007-11-02 2009-06-11 The Scripps Research Institute Genetically encoded boronate amino acid
KR20100091997A (ko) * 2007-11-02 2010-08-19 더 스크립스 리서치 인스티튜트 비천연 아미노산을 포함하는 단백질을 사용한 방향성 진화
JP2011527886A (ja) * 2007-12-11 2011-11-10 ザ スクリプス リサーチ インスティチュート メタノール資化性酵母ピキア・パストリスにおけるインビボ非天然アミノ酸発現
CA2712080A1 (en) * 2008-02-08 2009-08-13 The Scripps Research Institute Breaking immunological tolerance with a genetically encoded unnatural amino acid
CA2746213A1 (en) * 2008-12-09 2010-07-08 Wilson-Cook Medical Inc. Apparatus and methods for controlled release of tacking devices
US20090197339A1 (en) * 2008-12-10 2009-08-06 The Scripps Research Institute In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
WO2010068278A2 (en) 2008-12-10 2010-06-17 The Scripps Research Institute Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
WO2010089741A1 (en) * 2009-02-04 2010-08-12 Ben-Gurion University Of The Negev Research And Development Authority Systems and methods for bio-electricity production
JP6574754B2 (ja) 2013-03-19 2019-09-11 ベイジン シェノゲン ファーマ グループ リミテッド エストロゲン受容体関連疾患を処置するための抗体及び方法
US20150331624A1 (en) * 2014-05-19 2015-11-19 Kabushiki Kaisha Toshiba Host-controlled flash translation layer snapshot
CN110461951B (zh) 2017-03-09 2022-04-08 富士胶片株式会社 组合物、二色性物质、吸光各向异性膜、层叠体及图像显示装置
KR101956042B1 (ko) * 2017-07-13 2019-03-08 서강대학교산학협력단 표적 단백질 내 l-디하이드록시페닐알라닌의 도입 방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879905A (en) * 1996-08-29 1999-03-09 Massachusetts Institute Of Technology In vivo method of initiating protein synthesis with an amino acid other than methionine
EP1456360B1 (en) 2001-04-19 2015-06-03 The Scripps Research Institute Methods and composition for the production of orthoganal trna-aminoacyltrna synthetase pairs
WO2004035605A2 (en) 2002-10-16 2004-04-29 The Scripps Research Institute Glycoprotein synthesis
ATE429500T1 (de) 2002-10-16 2009-05-15 Scripps Research Inst Stellenspezifischer einbau von ketoaminosäuren in proteine
MXPA05006836A (es) 2002-12-22 2005-08-16 Scripps Research Inst Colecciones ordenadas de proteinas.
CN101223272B (zh) 2003-04-17 2013-04-03 斯克利普斯研究院 扩展真核生物遗传密码
CN102618605B (zh) 2003-06-18 2015-09-02 斯克利普斯研究院 非天然活性氨基酸遗传密码增加
WO2005007870A2 (en) 2003-07-07 2005-01-27 The Scripps Research Institute COMPOSITIONS OF ORTHOGONAL LEUCYL-tRNA AND AMINOACYL-tRNA SYNTHETASE PAIRS AND USES THEREOF
PT1666604E (pt) 2003-07-07 2008-05-19 Scripps Research Inst Composições de pares ortogonais de lisil-arnt e aminoacil-arnt-sintetase e suas utilizações
EP1658366A4 (en) 2003-07-07 2006-08-09 Scripps Research Inst COMPOSITIONS OF ORTHOGONAL GLUTAMYL-TRNA AND AMINOACYL-TRNA-SYNTHETASEPAARES AND THEIR USES

Also Published As

Publication number Publication date
IL201705A0 (en) 2011-08-01
CN1942579B (zh) 2013-06-26
JP2007508034A (ja) 2007-04-05
ES2396712T3 (es) 2013-02-25
US8008041B2 (en) 2011-08-30
US7811801B2 (en) 2010-10-12
IL206889A0 (en) 2010-12-30
MXPA06004087A (es) 2006-06-27
WO2005038002A2 (en) 2005-04-28
IL174947A (en) 2011-11-30
CA2541166A1 (en) 2005-04-28
US7494796B2 (en) 2009-02-24
BRPI0415308A (pt) 2006-12-05
IL174947A0 (en) 2006-08-20
CN1942579A (zh) 2007-04-04
EP1687401A4 (en) 2007-08-01
AU2004282577A1 (en) 2005-04-28
JP5657850B2 (ja) 2015-01-21
EP1687401A2 (en) 2006-08-09
WO2005038002A3 (en) 2006-11-23
US9783798B2 (en) 2017-10-10
US20090298124A1 (en) 2009-12-03
DK1687401T3 (da) 2013-02-04
US20070009990A1 (en) 2007-01-11
PT1687401E (pt) 2013-02-26
US20110008782A1 (en) 2011-01-13
US20050227318A1 (en) 2005-10-13
US20120100570A1 (en) 2012-04-26
EP1687401B1 (en) 2012-11-21
US8114654B2 (en) 2012-02-14
AU2004282577B2 (en) 2009-10-29
CN101532046A (zh) 2009-09-16

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