US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
CN100423777C
(zh)
*
|
2001-10-25 |
2008-10-08 |
杰南技术公司 |
糖蛋白组合物
|
EP2261250B1
(en)
|
2001-12-21 |
2015-07-01 |
Human Genome Sciences, Inc. |
GCSF-Albumin fusion proteins
|
WO2003059934A2
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US20070161087A1
(en)
*
|
2003-05-29 |
2007-07-12 |
Wolfgang Glaesner |
Glp-1 fusion proteins
|
AU2004251145C1
(en)
*
|
2003-06-12 |
2011-04-14 |
Eli Lilly And Company |
GLP-1 analog fusion proteins
|
ES2567634T3
(es)
|
2004-02-09 |
2016-04-25 |
Human Genome Sciences, Inc. |
Proteínas de fusión de albúmina
|
PL1831252T3
(pl)
*
|
2004-12-22 |
2009-11-30 |
Lilly Co Eli |
Preparaty białka fuzyjnego analogu GLP-1
|
CN101166545B
(zh)
*
|
2005-05-13 |
2011-06-15 |
伊莱利利公司 |
Glp-1聚乙二醇化的化合物
|
WO2007012188A1
(en)
*
|
2005-07-27 |
2007-02-01 |
Qinghua Wang |
GLP/1/EXENDM 4 IgG Fc FUSION CONSTRUCTS FOR TREATMENT OF DIABETES
|
CA2658678A1
(en)
|
2005-08-06 |
2007-02-15 |
Gerald J. Prud'homme |
Composition and method for prevention and treatment of type i diabetes
|
PT1767545E
(pt)
*
|
2005-09-22 |
2010-02-05 |
Biocompatibles Uk Ltd |
Polipéptidos de fusão glp-1 (péptido 1 do tipo glucagom) com resistência aumentada à peptidase
|
EP1948785B1
(en)
*
|
2005-10-24 |
2014-01-15 |
Janssen Biotech, Inc. |
Glp-2 mimetibodies, polypeptides, compositions, methods and uses
|
PT1965823T
(pt)
|
2005-11-04 |
2016-08-18 |
Glaxosmithkline Llc |
Métodos para administração de agentes hipoglicémicos
|
CN101534846B
(zh)
*
|
2005-11-07 |
2014-11-05 |
印第安纳大学研究及科技有限公司 |
显示生理学溶解性和稳定性的胰高血糖素类似物
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
EP1816201A1
(en)
|
2006-02-06 |
2007-08-08 |
CSL Behring GmbH |
Modified coagulation factor VIIa with extended half-life
|
EP2573111A1
(en)
|
2006-04-20 |
2013-03-27 |
Amgen Inc. |
GLP-1 compounds
|
JP5290177B2
(ja)
*
|
2006-08-31 |
2013-09-18 |
セントカー・インコーポレーテツド |
Glp−2ミメティボディ、ポリペプチド、組成物、方法および用途
|
EP2059606A4
(en)
*
|
2006-09-06 |
2010-04-07 |
Phasebio Pharmaceuticals Inc |
PEPTIDE FUSION THERAPEUTIC COMPOSITIONS
|
US8338376B2
(en)
*
|
2006-10-20 |
2012-12-25 |
Biogen Idec Ma Inc. |
Compositions comprising variant LT-B-R-IG fusion proteins
|
JP5448839B2
(ja)
|
2006-12-22 |
2014-03-19 |
ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー |
インビボで長い半減期を有する修飾された凝固因子
|
SG177953A1
(en)
*
|
2007-01-05 |
2012-02-28 |
Univ Indiana Res & Tech Corp |
Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
|
AU2011254001B2
(en)
*
|
2007-01-05 |
2012-08-02 |
Covx Technologies Ireland Limited |
Glucagon-like protein-1 receptor (GLP-1R) agonist compounds
|
US20090098130A1
(en)
*
|
2007-01-05 |
2009-04-16 |
Bradshaw Curt W |
Glucagon-like protein-1 receptor (glp-1r) agonist compounds
|
JP2008169195A
(ja)
*
|
2007-01-05 |
2008-07-24 |
Hanmi Pharmaceutical Co Ltd |
キャリア物質を用いたインスリン分泌ペプチド薬物結合体
|
ES2566385T3
(es)
|
2007-02-12 |
2016-04-12 |
Csl Behring Gmbh |
Aplicación terapéutica de inhibidores de la proteasa de serina de tipo Kazal
|
NZ578948A
(en)
|
2007-02-15 |
2012-03-30 |
Univ Indiana Res & Tech Corp |
Glucagon/glp-1 receptor co-agonists
|
JP5431171B2
(ja)
*
|
2007-03-15 |
2014-03-05 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
自己免疫障害の処置
|
DK2172479T3
(en)
*
|
2007-06-19 |
2016-12-19 |
Glytech Inc |
GLP-1 peptide having the sugar chain attached thereto
|
US7960336B2
(en)
*
|
2007-08-03 |
2011-06-14 |
Pharmain Corporation |
Composition for long-acting peptide analogs
|
ES2646614T3
(es)
*
|
2007-08-03 |
2017-12-14 |
Eli Lilly And Company |
Uso de un compuesto de FGF 21 y un compuesto de GLP 1 para el tratamiento de la obesidad
|
US8563527B2
(en)
*
|
2007-08-20 |
2013-10-22 |
Pharmain Corporation |
Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same
|
EP2031064A1
(de)
*
|
2007-08-29 |
2009-03-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Verfahren zur Steigerung von Proteintitern
|
AU2008318876B2
(en)
*
|
2007-10-30 |
2014-05-15 |
Indiana University Research And Technology Corporation |
Compounds exhibiting glucagon antagonist and GLP-1 agonist activity
|
EP2217701B9
(en)
|
2007-10-30 |
2015-02-18 |
Indiana University Research and Technology Corporation |
Glucagon antagonists
|
US20100317057A1
(en)
*
|
2007-12-28 |
2010-12-16 |
Novo Nordisk A/S |
Semi-recombinant preparation of glp-1 analogues
|
CA2713348C
(en)
*
|
2008-01-30 |
2018-10-09 |
Indiana University Research And Technology Corporation |
Ester-based peptide prodrugs
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
CA2727161A1
(en)
*
|
2008-06-17 |
2009-12-23 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility and stability physiological ph buffers
|
WO2009155258A2
(en)
|
2008-06-17 |
2009-12-23 |
Indiana University Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
CL2009001425A1
(es)
*
|
2008-06-17 |
2010-04-30 |
Univ Indiana Res & Tech Corp |
Analogos de glucagon con un aminoacido aromatico grande que carece de cadena lateral de imidazol que le confiere actividad agonista del receptor gip; composiciones farmaceutica; kit que los contiene y uso para reducir el aumento de peso, tratar la diabetes o inducir paralisis del tracto intestinal.
|
WO2009156137A1
(en)
|
2008-06-24 |
2009-12-30 |
Csl Behring Gmbh |
Factor viii, von willebrand factor or complexes thereof with prolonged in vivo half-life
|
CN105727261A
(zh)
|
2008-06-27 |
2016-07-06 |
杜克大学 |
包含弹性蛋白样肽的治疗剂
|
CA2739615C
(en)
|
2008-10-10 |
2017-12-05 |
Amgen Inc. |
Fgf21 mutants comprising polyethylene glycol and uses thereof
|
EP2376097A4
(en)
|
2008-12-19 |
2012-10-03 |
Univ Indiana Res & Tech Corp |
AMID-BASED PEPTIDE PRODRUGS OF THE GLUCAGON SUPERFAMILY
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
SG10201402038WA
(en)
*
|
2009-05-05 |
2014-07-30 |
Amgen Inc |
FGF21 Mutants And Uses Thereof
|
WO2010129600A2
(en)
|
2009-05-05 |
2010-11-11 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
IN2012DN00377A
(pl)
|
2009-06-16 |
2015-08-21 |
Univ Indiana Res & Tech Corp |
|
JP2012530493A
(ja)
*
|
2009-06-17 |
2012-12-06 |
アムジエン・インコーポレーテツド |
キメラポリペプチドおよびその使用
|
CN101993485B
(zh)
|
2009-08-20 |
2013-04-17 |
重庆富进生物医药有限公司 |
促胰岛素分泌肽类似物同源二聚体及其用途
|
KR101229610B1
(ko)
*
|
2009-10-09 |
2013-02-05 |
한남대학교 산학협력단 |
Glp-1 유사체의 융합체, 및 이를 유효성분으로 함유하는 당뇨병의 예방 또는 치료용 조성물
|
MX2012006397A
(es)
*
|
2009-12-02 |
2012-11-30 |
Amgen Inc |
PROTEINAS DE ENLACE QUE ENLAZAN A FGFR1C HUMANO, ß-KLOTHO HUMANA Y TANTO FGFR1C HUMANO COMO ß-KLOTHO HUMANA.
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
US8703701B2
(en)
|
2009-12-18 |
2014-04-22 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
BR112012018585A2
(pt)
|
2010-01-27 |
2017-01-10 |
Univ Indiana Res & Tech Corp |
conjungados e composições de glucagon antagonista-gip agonista para o tratamento de distúrbios metabólicos e de obesidade
|
EP2371857A1
(en)
|
2010-04-01 |
2011-10-05 |
CSL Behring GmbH |
Factor XII inhibitors for treating interstitial lung disease
|
US9517264B2
(en)
|
2010-04-15 |
2016-12-13 |
Amgen Inc. |
Human FGF receptor and β-Klotho binding proteins
|
RU2012151296A
(ru)
|
2010-04-30 |
2014-06-10 |
Санва Кагаку Кенкюсо Ко., Лтд |
Пептид для улучшения биостабильности биоактивного вещества и биоактивное вещество, имеющее повышенную биостабильность
|
WO2011143209A1
(en)
|
2010-05-13 |
2011-11-17 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting nuclear hormone receptor activity
|
BR112012028707A2
(pt)
|
2010-05-13 |
2019-09-24 |
Univ Indiana Res & Tech Corp |
composto de glucagon da superfamília de peptídeos exibindo atividade do receptor g com proteína acoplada, pró farmaco, dímero ou multímro, composição farmacêutica que o compreendem e método de administração do mesmo.
|
CN101891823B
(zh)
|
2010-06-11 |
2012-10-03 |
北京东方百泰生物科技有限公司 |
一种Exendin-4及其类似物融合蛋白
|
WO2011163012A2
(en)
|
2010-06-24 |
2011-12-29 |
Indiana University Research And Technology Corporation |
Amide based glucagon superfamily peptide prodrugs
|
WO2012010553A1
(en)
|
2010-07-20 |
2012-01-26 |
Novo Nordisk A/S |
N-terminal modified fgf21 compounds
|
ES2713952T3
(es)
|
2010-12-22 |
2019-05-24 |
Univ Indiana Res & Tech Corp |
Análogos de glucagón que muestran actividad de receptor de GIP
|
CA2824143C
(en)
|
2011-01-14 |
2018-12-18 |
Redwood Bioscience, Inc. |
Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
|
ES2646191T3
(es)
|
2011-03-09 |
2017-12-12 |
Csl Behring Gmbh |
Inhibidores de Factor XII para la administración con procedimientos médicos que comprenden contacto con superficies artificiales
|
EP2497489A1
(en)
|
2011-03-09 |
2012-09-12 |
CSL Behring GmbH |
Factor XII inhibitors for the treatment of silent brain ischemia and ischemia of other organs
|
US8969526B2
(en)
|
2011-03-29 |
2015-03-03 |
Roche Glycart Ag |
Antibody Fc variants
|
KR20140043793A
(ko)
|
2011-06-22 |
2014-04-10 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
글루카곤/glp-1 수용체 공동-작용물질
|
CA2839686C
(en)
|
2011-06-22 |
2019-12-24 |
Indiana University Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
US9518127B2
(en)
|
2011-07-22 |
2016-12-13 |
Csl Behring Gmbh |
Inhibitory anti-factor XII/XIIA monoclonal antibodies and their uses
|
UY34317A
(es)
|
2011-09-12 |
2013-02-28 |
Genzyme Corp |
Anticuerpo antireceptor de célula T (alfa)/ß
|
KR20130049671A
(ko)
|
2011-11-04 |
2013-05-14 |
한미사이언스 주식회사 |
생리활성 폴리펩타이드 결합체 제조 방법
|
KR20140097151A
(ko)
|
2011-11-17 |
2014-08-06 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
글루코코르티코이드 수용체 활성을 나타내는 글루카곤 슈퍼패밀리 펩티드
|
EP2623110A1
(en)
|
2012-01-31 |
2013-08-07 |
CSL Behring GmbH |
Factor XII inhibitors for the treatment of neurological inflammatory disorders
|
WO2013120939A1
(en)
|
2012-02-15 |
2013-08-22 |
Csl Behring Gmbh |
Von willebrand factor variants having improved factor viii binding affinity
|
CN104583232B
(zh)
|
2012-06-21 |
2018-04-13 |
印第安纳大学研究及科技有限公司 |
展现gip受体活性的胰高血糖素类似物
|
PT2872534T
(pt)
|
2012-07-13 |
2018-10-26 |
Roche Glycart Ag |
Anticorpos biespecíficos anti-vegf/anti-ang-2 e a sua utilização no tratamento de doenças oculares vasculares
|
CN104797601B
(zh)
*
|
2012-09-12 |
2019-08-30 |
建新公司 |
具有改变的糖基化和降低的效应物功能的包含fc的多肽
|
US9790268B2
(en)
|
2012-09-12 |
2017-10-17 |
Genzyme Corporation |
Fc containing polypeptides with altered glycosylation and reduced effector function
|
DK2925776T3
(en)
|
2012-11-27 |
2018-09-03 |
Biomarin Pharm Inc |
TARGETED THERAPEUTIC LYSOSOMAL ENZYMUS FUSION PROTEINS AND APPLICATIONS THEREOF
|
EP2926834A4
(en)
|
2012-11-27 |
2016-04-20 |
Alteogen Inc |
COMPOSITION FOR STABILIZING A FUSION PROTEIN IN WHICH A PROTEIN AND A DOMAIN FC ARE MERGED
|
AU2014224599B2
(en)
|
2013-03-08 |
2018-11-08 |
Csl Behring Gmbh |
Treatment and prevention of remote ischemia-reperfusion injury
|
MX370679B
(es)
|
2013-03-11 |
2019-12-19 |
Genzyme Corp |
Polipéptidos de unión hiperglicosilados.
|
RU2678134C2
(ru)
|
2013-03-14 |
2019-01-23 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Конъюгаты инсулин-инкретин
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
DK2796145T3
(da)
|
2013-04-22 |
2018-01-29 |
Csl Ltd |
Et kovalent kompleks af von Willebrand-faktor og faktor VIII linket af en disulfidbro
|
EP3013366B1
(en)
|
2013-06-28 |
2021-08-25 |
CSL Behring GmbH |
Combination therapy using a factor xii inhibitor and a c1-inhibitor
|
CN103408669B
(zh)
|
2013-08-01 |
2016-01-20 |
江苏泰康生物医药有限公司 |
Glp-1类似物融合蛋白,及其制备方法和用途
|
CN104592381A
(zh)
*
|
2013-10-31 |
2015-05-06 |
江苏万邦生化医药股份有限公司 |
一种利拉鲁肽中间体多肽的制备方法
|
EP3125921B1
(en)
|
2014-03-11 |
2020-07-08 |
Novartis AG |
Fgf21 variants for use in treating hiv-haart induced partial lipodystrophy
|
CN116333148A
(zh)
|
2014-03-19 |
2023-06-27 |
建新公司 |
靶向模块的位点特异性糖工程化
|
UA124182C2
(uk)
*
|
2014-03-31 |
2021-08-04 |
Ханмі Фарм. Ко., Лтд. |
Спосіб покращення розчинності фізіологічно активного білка або пептиду
|
BR112016029624A2
(pt)
|
2014-06-18 |
2017-10-24 |
Csl Behring Gmbh |
terapia usando um inibidor do fator xii em um distúrbio neurotraumático
|
AU2015283822B2
(en)
|
2014-07-02 |
2019-10-03 |
CSL Behring Lengnau AG |
Modified von willebrand factor
|
AU2015292889C1
(en)
|
2014-07-21 |
2023-01-19 |
Delinia, Inc. |
Molecules that selectively activate regulatory T cells for the treatment of autoimmune diseases
|
CN107106654B
(zh)
|
2014-08-11 |
2021-06-11 |
德里尼亚公司 |
选择性地活化调节性t细胞用于治疗自身免疫病的修饰的il-2变体
|
ES2822994T3
(es)
|
2014-09-24 |
2021-05-05 |
Univ Indiana Res & Tech Corp |
Conjugados de incretina-insulina
|
CN104293834B
(zh)
*
|
2014-10-11 |
2018-03-23 |
上海兴迪金生物技术有限公司 |
GLP‑1或其类似物与抗体Fc片段融合蛋白的制备方法
|
MX2017007458A
(es)
|
2014-12-23 |
2017-08-10 |
Novo Nordisk As |
Derivados del factor 21 de crecimiento de fibroblastos (fgf21) y sus usos.
|
KR101825048B1
(ko)
*
|
2014-12-31 |
2018-02-05 |
주식회사 제넥신 |
GLP 및 면역글로불린 하이브리드 Fc 융합 폴리펩타이드 및 이의 용도
|
MY188430A
(en)
|
2015-04-10 |
2021-12-08 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
AR105616A1
(es)
|
2015-05-07 |
2017-10-25 |
Lilly Co Eli |
Proteínas de fusión
|
BR112017023785A2
(pt)
|
2015-05-22 |
2018-07-17 |
Csl Behring Recombinant Facility Ag |
polipeptídeos do fator de von willebrand truncados para tratar hemofilia
|
MX2017014872A
(es)
|
2015-05-22 |
2018-07-06 |
Csl Behring Recombinant Facility Ag |
Metodos para preparar factor de von willebrand modificado.
|
TWI622596B
(zh)
|
2015-10-26 |
2018-05-01 |
美國禮來大藥廠 |
升糖素受體促效劑
|
KR102670157B1
(ko)
|
2015-10-28 |
2024-05-29 |
주식회사유한양행 |
이중 작용 단백질 및 이를 포함하는 약학적 조성물
|
KR102668200B1
(ko)
|
2015-10-28 |
2024-05-23 |
주식회사유한양행 |
지속형 fgf21 융합 단백질 및 이를 포함하는 약학적 조성물
|
EP3184149A1
(en)
|
2015-12-23 |
2017-06-28 |
Julius-Maximilians-Universität Würzburg |
Soluble glycoprotein v for treating thrombotic diseases
|
WO2017112824A2
(en)
|
2015-12-23 |
2017-06-29 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
SG11201805494WA
(en)
|
2016-01-07 |
2018-07-30 |
Csl Behring Recombinant Facility Ag |
Mutated von willebrand factor
|
US10806774B2
(en)
|
2016-01-07 |
2020-10-20 |
CSL Behring Lengnau AG |
Mutated truncated von Willebrand Factor
|
US20170204154A1
(en)
|
2016-01-20 |
2017-07-20 |
Delinia, Inc. |
Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
|
KR20180132831A
(ko)
|
2016-04-06 |
2018-12-12 |
시에스엘 리미티드 |
죽상동맥경화증의 치료 방법
|
US11208632B2
(en)
|
2016-04-26 |
2021-12-28 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
US10336812B2
(en)
*
|
2016-05-10 |
2019-07-02 |
Janssen Biotech, Inc. |
GDF15 fusion proteins and uses thereof
|
CN106279437B
(zh)
|
2016-08-19 |
2017-10-31 |
安源医药科技(上海)有限公司 |
高糖基化人凝血因子viii融合蛋白及其制备方法与用途
|
US11123438B2
(en)
|
2016-08-19 |
2021-09-21 |
Ampsource Biopharma Shanghai Inc. |
Linker peptide for constructing fusion protein
|
CN107759694B
(zh)
|
2016-08-19 |
2023-01-13 |
安源医药科技(上海)有限公司 |
双特异性抗体及其制备方法与用途
|
US11077172B2
(en)
|
2016-11-08 |
2021-08-03 |
Delinia, Inc. |
IL-2 variants for the treatment of psoriasis
|
EP3568149A4
(en)
|
2016-11-10 |
2020-07-22 |
Yuhan Corporation |
PHARMACEUTICAL COMPOSITION CONSISTING OF FUSION PROTEINS INTENDED FOR THE PREVENTION OR TREATMENT OF HEPATITIS, HEPATIC FIBROSIS AND HEPATIC CIRRHOSIS
|
CA3043250A1
(en)
|
2016-11-11 |
2018-05-17 |
CSL Behring Lengnau AG |
Truncated von willebrand factor polypeptides for treating hemophilia
|
AU2017358865A1
(en)
|
2016-11-11 |
2019-05-09 |
CSL Behring Lengnau AG |
Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder
|
EP3351262A1
(en)
|
2016-12-30 |
2018-07-25 |
Istanbul Universitesi Rektorlugu |
Curaglutide for in treatment of prediabetes, diabetes, obesity and metabolic diseases associated thereto
|
JOP20190177A1
(ar)
|
2017-01-17 |
2019-07-16 |
Amgen Inc |
طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr)
|
EP3612637A4
(en)
|
2017-04-21 |
2021-01-27 |
Yuhan Corporation |
DOUBLE-FUNCTION PROTEIN PRODUCTION PROCESS AND ITS DERIVATIVES
|
ES2963464T3
(es)
|
2017-06-01 |
2024-03-27 |
Lilly Co Eli |
Dulaglutida para el tratamiento de la enfermedad renal crónica
|
WO2018234518A1
(en)
|
2017-06-22 |
2018-12-27 |
CSL Behring Lengnau AG |
MODULATION OF IMMUNOGENICITY OF FVIII BY VWF TRONQUÉ
|
EP3684793A1
(en)
|
2017-09-22 |
2020-07-29 |
Regeneron Pharmaceuticals, Inc. |
Glucagon-like peptide 1 receptor agonists and uses thereof
|
JP7221956B2
(ja)
|
2017-11-21 |
2023-02-14 |
イーライ リリー アンド カンパニー |
デュラグルチドを使用する方法およびデュラグルチドを含有する組成物
|
CN111518770B
(zh)
|
2017-12-19 |
2023-01-06 |
北京吉源生物科技有限公司 |
一种表达glp1和fgf21的干细胞及其用途
|
US11491235B2
(en)
|
2017-12-22 |
2022-11-08 |
Kb Biomed Inc. |
Oral gene carrier and use thereof
|
WO2019140021A1
(en)
|
2018-01-12 |
2019-07-18 |
Eli Lilly And Company |
Combination therapy
|
US11679143B2
(en)
|
2018-02-08 |
2023-06-20 |
Sunshine Lake Pharma Co., Ltd. |
FGF21 variant, fusion protein and application thereof
|
KR20200135618A
(ko)
|
2019-05-23 |
2020-12-03 |
㈜ 디앤디파마텍 |
폴리펩티드를 포함하는 비알코올성 지방간 질환의 예방 또는 치료용 약학 조성물
|
BR112021000933A2
(pt)
|
2018-07-19 |
2021-04-27 |
D&D Pharmatech Inc. |
polipeptídeo, composição farmacêutica, método de preparação dela e método de prevenção ou tratamento de doenças
|
CN110878127B
(zh)
|
2018-09-06 |
2022-06-28 |
浙江柏拉阿图医药科技有限公司 |
长效重组GLP1-Fc-CD47蛋白及其制备和用途
|
CN111234000B
(zh)
*
|
2018-11-28 |
2023-05-26 |
鲁南制药集团股份有限公司 |
艾塞纳肽类似物
|
CN111269312B
(zh)
*
|
2018-12-04 |
2023-05-09 |
鲁南制药集团股份有限公司 |
一种异源融合蛋白质
|
CN109836486B
(zh)
*
|
2019-01-30 |
2020-09-08 |
北京双因生物科技有限公司 |
成纤维生长因子21变体、其融合蛋白及其用途
|
WO2020177712A1
(en)
*
|
2019-03-05 |
2020-09-10 |
Dongguan Hec Biopharmaceutical R&D Co., Ltd. |
A polypeptide molecule and application thereof
|
AU2020233876A1
(en)
|
2019-03-08 |
2021-09-23 |
Amgen Inc. |
Growth differentiation factor 15 combination therapy
|
JP2022525883A
(ja)
|
2019-03-15 |
2022-05-20 |
イーライ リリー アンド カンパニー |
保存製剤
|
CA3177693A1
(en)
|
2019-04-05 |
2020-10-05 |
Eli Lilly And Company |
Therapeutic uses of dulaglutide
|
US20220211808A1
(en)
|
2019-05-17 |
2022-07-07 |
Universitaet Zuerich |
Haptoglobin for use in treating an adverse secondary neurological outcome following a haemorrhagic stroke
|
EP3994162A1
(en)
|
2019-07-04 |
2022-05-11 |
CSL Behring Lengnau AG |
A truncated von willebrand factor (vwf) for increasing the in vitro stability of coagulation factor viii
|
KR20220054689A
(ko)
|
2019-10-15 |
2022-05-03 |
일라이 릴리 앤드 캄파니 |
재조합적으로 조작된, 리파제/에스테라제-결핍 포유동물 세포주
|
WO2021094344A1
(en)
|
2019-11-11 |
2021-05-20 |
CSL Behring Lengnau AG |
Polypeptides for inducing tolerance to factor viii
|
WO2021139744A1
(en)
|
2020-01-11 |
2021-07-15 |
Beijing Ql Biopharmaceutical Co., Ltd. |
Conjugates of fusion proteins of glp-1 and fgf21
|
US11981718B2
(en)
|
2020-05-27 |
2024-05-14 |
Ampsource Biopharma Shanghai Inc. |
Dual-function protein for lipid and blood glucose regulation
|
CA3190399A1
(en)
|
2020-08-24 |
2022-03-03 |
James M. Wilson |
Viral vectors encoding glp-1 receptor agonist fusions and uses thereof in treating metabolic diseases
|
CN114106194B
(zh)
*
|
2020-08-31 |
2024-01-16 |
中国科学院天津工业生物技术研究所 |
一种用于治疗糖尿病和/或肥胖症的融合蛋白
|
US20240000908A1
(en)
|
2020-11-20 |
2024-01-04 |
Csl Behring Gmbh |
Method for Treating Antibody-Mediated Rejection
|
CN114685644A
(zh)
|
2020-12-29 |
2022-07-01 |
苏州康宁杰瑞生物科技有限公司 |
一种人glp-1多肽变体及其应用
|
CN117136068A
(zh)
|
2021-02-01 |
2023-11-28 |
瑞士杰特贝林生物制品有限公司 |
治疗或预防出血性中风后不良继发性神经学后果的方法
|
CA3217518A1
(en)
|
2021-05-07 |
2022-11-10 |
Rebecca Butcher |
Expression system for producing a recombinant haptoglobin (hp) beta chain
|
AU2022308120A1
(en)
|
2021-07-06 |
2024-02-08 |
Suzhou Alphamab Co., Ltd. |
Fusion protein and application thereof
|
TW202409070A
(zh)
|
2022-05-18 |
2024-03-01 |
美商普羅托莫科技公司 |
芳族含硼化合物及相關胰島素類似物
|
CN114774496B
(zh)
*
|
2022-06-21 |
2022-10-04 |
北京惠之衡生物科技有限公司 |
一种高密度发酵制备glp-1类似物的方法
|
WO2024047219A1
(en)
|
2022-09-02 |
2024-03-07 |
Csl Behring Ag |
Haptoglobin for use in treating or preventing exaggerated erectile response or erectile dysfunction
|
WO2024064842A1
(en)
|
2022-09-21 |
2024-03-28 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating obesity, diabetes, and liver dysfunction
|
WO2024068848A1
(en)
|
2022-09-28 |
2024-04-04 |
Zealand Pharma A/S |
Methods for treating obesity
|
WO2024132147A1
(en)
|
2022-12-22 |
2024-06-27 |
Lifearc |
Galanin-2 receptor agonists
|
WO2024197132A1
(en)
|
2023-03-23 |
2024-09-26 |
Eli Lilly And Company |
Methods of producing fc-containing proteins
|