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PH18220A - Thiazolidinylalkylene piperazine derivatives - Google Patents

Thiazolidinylalkylene piperazine derivatives

Info

Publication number
PH18220A
PH18220A PH27654A PH27654A PH18220A PH 18220 A PH18220 A PH 18220A PH 27654 A PH27654 A PH 27654A PH 27654 A PH27654 A PH 27654A PH 18220 A PH18220 A PH 18220A
Authority
PH
Philippines
Prior art keywords
thiazolidinylalkylene
piperazine derivatives
piperazine
derivatives
thiazolidinylalkylene piperazine
Prior art date
Application number
PH27654A
Inventor
Davis L Temple Jr
Richard E Yeager
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of PH18220A publication Critical patent/PH18220A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
PH27654A 1981-08-03 1982-07-30 Thiazolidinylalkylene piperazine derivatives PH18220A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/289,352 US4367335A (en) 1981-08-03 1981-08-03 Thiazolidinylalkylene piperazine derivatives

Publications (1)

Publication Number Publication Date
PH18220A true PH18220A (en) 1985-04-30

Family

ID=23111164

Family Applications (1)

Application Number Title Priority Date Filing Date
PH27654A PH18220A (en) 1981-08-03 1982-07-30 Thiazolidinylalkylene piperazine derivatives

Country Status (28)

Country Link
US (1) US4367335A (en)
JP (2) JPS5826877A (en)
KR (1) KR880001478B1 (en)
AT (1) AT381705B (en)
AU (1) AU560655B2 (en)
BE (1) BE894022A (en)
CA (1) CA1172636A (en)
CH (1) CH652398A5 (en)
DE (1) DE3228990A1 (en)
DK (1) DK162991C (en)
ES (1) ES8307800A1 (en)
FI (1) FI76793C (en)
FR (1) FR2510572B1 (en)
GB (1) GB2106104B (en)
GR (1) GR76172B (en)
HU (1) HU191187B (en)
IE (1) IE53641B1 (en)
IL (1) IL66434A0 (en)
IT (1) IT1149329B (en)
LU (1) LU84316A1 (en)
NL (1) NL8203034A (en)
NZ (1) NZ201159A (en)
OA (1) OA07172A (en)
PH (1) PH18220A (en)
PT (1) PT75366B (en)
SE (1) SE452320B (en)
YU (1) YU44074B (en)
ZA (1) ZA825479B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
CA1278792C (en) * 1985-05-06 1991-01-08 Joseph P. Yevich Antipsychotic fused-ring pyridinylpiperazine derivatives
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
US4675403A (en) * 1985-10-16 1987-06-23 American Home Products Corporation 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity
US4784998A (en) * 1987-04-06 1988-11-15 Bristol-Myers Company 1,3,4-oxadiazole pyschotropic compounds
US5801186A (en) 1987-11-20 1998-09-01 Hoechst Marion Roussel, Inc. 3- 4-(1-substituted-4-piperazinyl)butyl!-4-thiazolidinone and related compounds
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US5116970A (en) * 1988-02-18 1992-05-26 New James S Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
FR2642759B1 (en) * 1989-02-09 1991-05-17 Laboratorios Esteve Sa PYRIMIDYL-PIPERAZINYL-ALKYL AZOLES DERIVATIVES WITH ANXIOLYTIC AND / OR TRANQUILIZING ACTIVITY
JPH0415948U (en) * 1990-05-31 1992-02-10
US5194436A (en) * 1991-01-10 1993-03-16 Hoechst-Roussel Pharmaceuticals Inc. 1-piperazinyl-2-butenes and -2-butynes
US5130315A (en) * 1991-01-10 1992-07-14 Raymond R. Wittekind 1-piperazinyl-2-butenes and -2-butynes
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
WO2003093236A1 (en) * 2002-05-02 2003-11-13 Euro-Celtique, S.A. 1-(pyrid-2-yl)-piperazine compounds as metabotropic glutamate receptor inhibitor
WO2006013445A2 (en) * 2004-07-28 2006-02-09 Ranbaxy Laboratories Limited Thiazolidinedione derivatives as alpha adrenergic receptor antagonists

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2672460A (en) * 1952-06-24 1954-03-16 American Cyanamid Co Disubstituted piperazines and methods of preparing the same
US2748125A (en) * 1954-04-26 1956-05-29 American Cyanamid Co 1-substituted-4-sulfamylpiperazine and method of preparing the same
IT649883A (en) * 1960-05-24
FR1435004A (en) * 1965-02-04 1966-04-15 Sobio Lab Thiazolidine-dione-2, 4- derivatives and method of preparation
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
DE1695410A1 (en) * 1967-04-20 1971-04-08 Merck Patent Gmbh Process for the preparation of 1- (thiazolyl-5-alkyl) -4- (pyridyl-2) -piperazines
US3635976A (en) * 1967-12-20 1972-01-18 Pennwalt Corp 1 - heterocyclic alkyl-1 2 3 4-tetrahydroquinazolinones and analgesic intermediates thereof
US3822266A (en) * 1968-12-24 1974-07-02 Hoffmann La Roche (3-(1-piperazinyl)-2-hydroxy-propoxy)acetanilides
BE759371A (en) * 1969-11-24 1971-05-24 Bristol Myers Co HETEROCYCLICAL AZASPIRODECANEDIONES AND METHODS FOR THEIR PREPARATION
IT1052119B (en) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti TRIAZOLINONE DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
DE2263211A1 (en) * 1972-12-23 1974-07-04 Boehringer Sohn Ingelheim NEW ARYLPIPERAZINE AND PROCESS FOR THEIR PRODUCTION
US3919230A (en) * 1974-02-07 1975-11-11 Smithkline Corp {62 -Naphthylmethyl piperazinyl derivatives
FR2285883A1 (en) * 1974-09-30 1976-04-23 Cerm Cent Europ Rech Mauvernay NEW CHEMICAL COMPOUNDS WITH BRONCHOSPASMOLYTIC AND ANTITUSSIVE ACTIVITY, AND PROCESS FOR OBTAINING THEM
US3940398A (en) * 1975-01-23 1976-02-24 E. R. Squibb & Sons, Inc. 2-[[4-(Azine or diazine or triazine)-1-piperazinyl]alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US4001237A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company Oxazole, isoxazole, thiazole and isothiazole amides
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
GB1518559A (en) * 1976-04-12 1978-07-19 Science Union & Cie Naphthyl derivatives processes for their preparation an pharmaceutical compositions containing them
US4078063A (en) * 1976-09-24 1978-03-07 Merck & Co., Inc. Piperazinylpyridines
US4101548A (en) * 1977-02-22 1978-07-18 Bristol-Myers Company 1,2,3-Thiadiazole amides
HU173380B (en) * 1977-02-25 1979-04-28 Richter Gedeon Vegyeszet Process for producing new pyridyl-piperazine derivatives and acid additional salts thereof
DE2727469A1 (en) * 1977-06-18 1978-12-21 Hoechst Ag NEW HEXAHYDROPYRIMIDINE, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
EP0002978B1 (en) * 1977-12-29 1982-10-06 Synthelabo Thiazolidinedione-2,4 derivatives, their preparation and pharmaceutical applications
FR2418798A1 (en) * 1978-03-03 1979-09-28 Science Union & Cie NEW DISUBSTITUTED PIPERAZINES, THEIR METHODS OF PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
FI791926A (en) * 1978-06-20 1979-12-21 Synthelabo PHENYLPIPERAZINE DERIVATIVES
US4161595A (en) * 1978-10-02 1979-07-17 Bristol-Myers Company Levulinic acid salt

Also Published As

Publication number Publication date
FR2510572A1 (en) 1983-02-04
GB2106104B (en) 1985-05-09
SE8204550L (en) 1983-02-04
PT75366B (en) 1985-11-20
NL8203034A (en) 1983-03-01
CH652398A5 (en) 1985-11-15
CA1172636A (en) 1984-08-14
DK162991C (en) 1992-06-01
IE53641B1 (en) 1989-01-04
LU84316A1 (en) 1983-06-07
BE894022A (en) 1983-02-03
ATA299482A (en) 1986-04-15
JPS5826877A (en) 1983-02-17
IL66434A0 (en) 1982-12-31
PT75366A (en) 1982-09-01
OA07172A (en) 1984-04-30
IE821852L (en) 1983-02-03
ES514264A0 (en) 1983-08-01
FI76793C (en) 1988-12-12
NZ201159A (en) 1985-10-11
SE8204550D0 (en) 1982-08-02
DE3228990A1 (en) 1983-03-03
KR880001478B1 (en) 1988-08-13
FI76793B (en) 1988-08-31
DK162991B (en) 1992-01-06
YU44074B (en) 1990-02-28
IT1149329B (en) 1986-12-03
JPH02270821A (en) 1990-11-05
FI822667A0 (en) 1982-07-30
IT8248909A0 (en) 1982-07-29
DK343682A (en) 1983-02-04
KR840001167A (en) 1984-03-28
AT381705B (en) 1986-11-25
YU158682A (en) 1985-04-30
SE452320B (en) 1987-11-23
ES8307800A1 (en) 1983-08-01
FR2510572B1 (en) 1986-05-09
FI822667L (en) 1983-02-04
ZA825479B (en) 1983-04-27
AU560655B2 (en) 1987-04-16
GB2106104A (en) 1983-04-07
HU191187B (en) 1987-01-28
GR76172B (en) 1984-08-03
JPH0371410B2 (en) 1991-11-13
AU8566382A (en) 1983-02-10
US4367335A (en) 1983-01-04
JPH0235754B2 (en) 1990-08-13

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