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PH12015502316A1 - Oral formulation comprising extract of coptis rhizome having masked bitter taste - Google Patents

Oral formulation comprising extract of coptis rhizome having masked bitter taste

Info

Publication number
PH12015502316A1
PH12015502316A1 PH12015502316A PH12015502316A PH12015502316A1 PH 12015502316 A1 PH12015502316 A1 PH 12015502316A1 PH 12015502316 A PH12015502316 A PH 12015502316A PH 12015502316 A PH12015502316 A PH 12015502316A PH 12015502316 A1 PH12015502316 A1 PH 12015502316A1
Authority
PH
Philippines
Prior art keywords
extract
bitter taste
oral formulation
coptis rhizome
masked bitter
Prior art date
Application number
PH12015502316A
Inventor
Choi Youn Woong
Min Byung Gu
Ha Dea Chul
Cho Sang Min
Song Hee Yong
Park Hee Chan
Ahn Ji Hyun
Original Assignee
Korea United Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea United Pharm Inc filed Critical Korea United Pharm Inc
Publication of PH12015502316A1 publication Critical patent/PH12015502316A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to an oral formulation having masked bitter taste, which comprises an extract of Coptis rhizome and a cation-exchange resin having a sulfonic acid group, and to a preparation method thereof.
PH12015502316A 2013-04-29 2015-10-06 Oral formulation comprising extract of coptis rhizome having masked bitter taste PH12015502316A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130047566A KR101580119B1 (en) 2013-04-29 2013-04-29 An orally administered drug, comprising extract of coptidis rhizome with bitter taste thereof masked
PCT/KR2014/003797 WO2014178617A1 (en) 2013-04-29 2014-04-29 Oral formulation comprising extract of coptis rhizome having masked bitter taste

Publications (1)

Publication Number Publication Date
PH12015502316A1 true PH12015502316A1 (en) 2016-02-10

Family

ID=51843675

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12015502316A PH12015502316A1 (en) 2013-04-29 2015-10-06 Oral formulation comprising extract of coptis rhizome having masked bitter taste

Country Status (9)

Country Link
EP (1) EP2991624A4 (en)
KR (1) KR101580119B1 (en)
CN (1) CN105188669A (en)
BR (1) BR112015026635A2 (en)
HK (1) HK1212912A1 (en)
MX (1) MX2015014623A (en)
PH (1) PH12015502316A1 (en)
RU (1) RU2667638C2 (en)
WO (1) WO2014178617A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2937077B1 (en) * 2014-04-24 2021-10-06 Montero Gida Sanayi Ve Ticaret A.S. Oral liquid formulations comprising herbal extracts
KR102528183B1 (en) * 2021-01-27 2023-05-03 충북대학교 산학협력단 Wet granule formulation containing Centipeda minima extract and ion exchange resin, and method for preparing the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4780429B2 (en) * 2000-04-07 2011-09-28 大正製薬株式会社 Minoxidil-containing preparation
EP2307034B1 (en) * 2008-06-13 2017-07-26 Ahn-Gook Pharmaceutical Co., Ltd. Extract of coptidis rhizoma and novel use thereof in treating respiratory disease
CN101716220B (en) 2009-11-20 2012-07-04 杭州平和安康医药科技有限公司 Shielding alkaloid traditional Chinese medicine
JP2011148776A (en) * 2009-12-22 2011-08-04 Taisho Pharmaceutical Co Ltd Liquid preparation composition
CN102335400A (en) * 2010-07-16 2012-02-01 冯相建 Cream for treating chilblain
CN101982200B (en) * 2010-10-28 2012-05-30 中国中医科学院广安门医院 Rhizoma coptidis total alkaloids resin complexes, sustained-release preparation thereof and preparation method thereof
CN102813928A (en) * 2011-06-09 2012-12-12 上海张江中药现代制剂技术工程研究中心 Method for modifying bitter taste of berberine, berberine hydrochloride and related compound preparations
CN110198220A (en) 2018-02-26 2019-09-03 中国移动通信有限公司研究院 A kind of scalable appearance method, device and equipment of VNF

Also Published As

Publication number Publication date
HK1212912A1 (en) 2016-06-24
CN105188669A (en) 2015-12-23
RU2015142432A (en) 2017-06-05
EP2991624A4 (en) 2016-12-07
WO2014178617A1 (en) 2014-11-06
KR20140129459A (en) 2014-11-07
MX2015014623A (en) 2016-03-01
RU2667638C2 (en) 2018-09-21
EP2991624A1 (en) 2016-03-09
BR112015026635A2 (en) 2017-07-25
KR101580119B1 (en) 2015-12-29

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