PA8784701A1 - Proceso y dispersión sólida que contiene revaprazan para la preparación del mismo - Google Patents
Proceso y dispersión sólida que contiene revaprazan para la preparación del mismoInfo
- Publication number
- PA8784701A1 PA8784701A1 PA20088784701A PA8784701A PA8784701A1 PA 8784701 A1 PA8784701 A1 PA 8784701A1 PA 20088784701 A PA20088784701 A PA 20088784701A PA 8784701 A PA8784701 A PA 8784701A PA 8784701 A1 PA8784701 A1 PA 8784701A1
- Authority
- PA
- Panama
- Prior art keywords
- preparation
- solid dispersion
- revapraze
- same
- dispersion containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCIÓN PROPORCIONA UNA DISPERSIÓN SÓLIDA EN DONDE LAS PARTÍCULAS DE REVAPRAZAN SON MODIFICADAS EN LA SUPERFICIE CON UN POLÍMERO SOLUBLE EN AGUA, UN SACÁRIDO SOLUBLE EN AGUA, UN SURFACTANTE O UNA MEZCLA DE ESO Y UN PROCESO PARA LA PREPARACIÓN DE LA MISMA.LA PRESENTE INVENCIÓN TAMBIÉN PROPORCIONA UNA COMPOSICIÓN FARMACÉUTICA QUE CONTIENE DISPERSIÓN SÓLIDA Y UN PROCESO PARA LA PREPARACIÓN DE LA COMPOSICIÓN FARMACÉUTICA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20060132722 | 2006-12-22 | ||
KR1020070135270A KR100954828B1 (ko) | 2006-12-22 | 2007-12-21 | 레바프라잔 함유 고체분산체 및 그의 제조방법 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8784701A1 true PA8784701A1 (es) | 2009-07-23 |
Family
ID=39562674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20088784701A PA8784701A1 (es) | 2006-12-22 | 2008-06-13 | Proceso y dispersión sólida que contiene revaprazan para la preparación del mismo |
Country Status (20)
Country | Link |
---|---|
US (1) | US8663658B2 (es) |
EP (1) | EP2101737B1 (es) |
JP (1) | JP5484910B2 (es) |
KR (1) | KR100954828B1 (es) |
CN (1) | CN101600419B (es) |
AR (1) | AR067084A1 (es) |
AU (1) | AU2007339080B2 (es) |
BR (1) | BRPI0720472A2 (es) |
CA (1) | CA2673536A1 (es) |
ES (1) | ES2496166T3 (es) |
HK (1) | HK1138517A1 (es) |
MX (1) | MX2009006105A (es) |
MY (1) | MY146557A (es) |
PA (1) | PA8784701A1 (es) |
PE (1) | PE20090424A1 (es) |
RU (1) | RU2461382C2 (es) |
SA (1) | SA08290368B1 (es) |
TW (1) | TW200927124A (es) |
WO (1) | WO2008078922A1 (es) |
ZA (1) | ZA200905094B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007339080B2 (en) | 2006-12-22 | 2012-09-27 | Yuhan Corporation | Revaprazan-containing solid dispersion and process for the preparation thereof |
CN101874775B (zh) * | 2010-05-31 | 2013-03-13 | 沈阳药科大学 | 盐酸瑞伐拉赞纳米混悬剂及其制备方法 |
KR101739816B1 (ko) * | 2010-12-01 | 2017-05-25 | 주식회사유한양행 | 레바프라잔 또는 그의 염을 함유하는 주사용 액제 조성물 또는 주사용 건조 분말 |
KR101739815B1 (ko) * | 2010-12-01 | 2017-05-26 | 주식회사유한양행 | 레바프라잔 또는 그의 염을 함유하는 주사용 액제 조성물 |
KR101730865B1 (ko) | 2011-02-11 | 2017-04-27 | 주식회사유한양행 | 레바프라잔-함유 나노입자를 포함하는 경구투여용 약학 조성물 및 그의 제조방법 |
KR101739818B1 (ko) * | 2011-05-20 | 2017-05-26 | 주식회사유한양행 | 레바프라잔 또는 그의 염을 함유하는 현탁액 형태의 경구투여용 약학 조성물 |
KR101739820B1 (ko) * | 2012-03-28 | 2017-05-25 | 주식회사유한양행 | 레바프라잔 또는 그의 염을 함유하는 비수성 액체 형태의 경구투여용 약학 조성물 |
WO2015175505A1 (en) * | 2014-05-15 | 2015-11-19 | Lundbeck Llc | Tetrabenazine modified release formulation |
WO2015193309A1 (en) * | 2014-06-18 | 2015-12-23 | F. Hoffmann-La Roche Ag | New pharmaceutical composition comprising non-ionic surfactants |
CN104825410A (zh) * | 2015-05-04 | 2015-08-12 | 海南海力制药有限公司 | 一种盐酸瑞伐拉赞片及其制备方法 |
CA2987867C (en) | 2015-06-09 | 2023-06-27 | Capsugel Belgium Nv | Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules |
CN105288636B (zh) * | 2015-12-11 | 2019-05-07 | 北京科莱博医药开发有限责任公司 | 增溶体系、固体分散体及药物制剂 |
WO2017106130A1 (en) * | 2015-12-16 | 2017-06-22 | Merck Sharp & Dohme Corp. | Process for preparing pharmaceutical compositions |
CN105687150B (zh) * | 2016-03-15 | 2019-12-10 | 常州市第四制药厂有限公司 | 一种盐酸瑞伐拉赞组合物及制备方法 |
CN106361721A (zh) * | 2016-08-31 | 2017-02-01 | 佛山市弘泰药物研发有限公司 | 一种盐酸瑞伐拉赞胶囊及其制备方法 |
PT110585B (pt) * | 2018-02-22 | 2021-04-22 | Hovione Farmaciencia Sa | Processo de produção contínua de partículas compreendendo secagem por atomização com preparação contínua da solução de atomização |
US20220023216A1 (en) | 2019-06-26 | 2022-01-27 | Ricoh Company, Ltd. | Instantly soluble particle and method for producing the same |
WO2020261619A1 (ja) | 2019-06-26 | 2020-12-30 | 株式会社リコー | 医薬組成物 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05255125A (ja) | 1992-02-29 | 1993-10-05 | Upjohn Co:The | 徐放性製剤およびその製法 |
ES2201112T3 (es) * | 1994-08-13 | 2004-03-16 | Yuhan Corporation | Nuevos derivados de pirimidina y procedimientos para su preparacion. |
KR0157075B1 (ko) * | 1994-08-13 | 1998-11-16 | 김태훈 | 신규의 피리미딘 유도체 및 그의 제조방법 |
WO1996041628A1 (fr) * | 1995-06-12 | 1996-12-27 | Ono Pharmaceutical Co., Ltd. | Granules contenant du pranlukast, procede de production des granules et procede de reduction de la cohesion du pranlukast |
US5955475A (en) * | 1997-06-30 | 1999-09-21 | Endo Pharmaceuticals Inc. | Process for manufacturing paroxetine solid dispersions |
IT1294760B1 (it) | 1997-09-03 | 1999-04-12 | Jagotec Ag | Procedimento per la preparazione di compresse farmaceutiche in grado di cedere,secondo schemi predeterminabili, principi attivi poco |
DK1227797T3 (da) * | 1999-11-12 | 2005-05-30 | Abbott Lab | Farmaceutiske faststofdispersionsformuleringer |
EP1239831B1 (en) * | 1999-12-23 | 2012-10-31 | Mayne Pharma International Pty Ltd. | Improved pharmaceutical compositions for poorly soluble drugs |
AU7105501A (en) * | 2000-07-17 | 2002-01-30 | Yamanouchi Pharma Co Ltd | Pharmaceutical composition improved in peroral absorbability |
US8206741B2 (en) * | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
ATE243028T1 (de) * | 2001-07-11 | 2003-07-15 | Applied Pharma Res | Fettlösliche substanzen enthaltende granulate und verfahren zu ihrer herstellung |
PL371319A1 (en) * | 2002-01-11 | 2005-06-13 | Takeda Pharmaceutical Company Limited | Coumarin derivatives, process for their production and use thereof |
MXPA05006802A (es) * | 2002-12-19 | 2005-09-08 | Pharmacia Corp | Formulacion no higroscopica que comprende un farmaco higroscopico. |
US20050096365A1 (en) * | 2003-11-03 | 2005-05-05 | David Fikstad | Pharmaceutical compositions with synchronized solubilizer release |
KR101118930B1 (ko) * | 2003-11-14 | 2012-03-14 | 아지노모토 가부시키가이샤 | 페닐알라닌 유도체의 고체 분산체 또는 고체 분산체 의약제제 |
CA2582767C (en) | 2004-10-25 | 2011-05-24 | Japan Tobacco Inc. | Solid formulation with improved solubility and stability and method for producing said formulation |
US20060165797A1 (en) * | 2005-01-12 | 2006-07-27 | Pozen Inc. | Dosage form for treating gastrointestinal disorders |
WO2007070164A1 (en) * | 2005-10-19 | 2007-06-21 | The Curators Of The University Of Missouri | Pharmaceutical composition comprising a proton pump inhibitor, a buffering agent and an anti-h. pylori active substance and methods of using same |
US7776873B2 (en) | 2005-12-01 | 2010-08-17 | Yuhan Corporation | Method for treating damage to gastric mucosa |
AU2007339080B2 (en) | 2006-12-22 | 2012-09-27 | Yuhan Corporation | Revaprazan-containing solid dispersion and process for the preparation thereof |
-
2007
- 2007-12-21 AU AU2007339080A patent/AU2007339080B2/en not_active Ceased
- 2007-12-21 CN CN2007800475422A patent/CN101600419B/zh active Active
- 2007-12-21 US US12/520,037 patent/US8663658B2/en not_active Expired - Fee Related
- 2007-12-21 BR BRPI0720472-8A patent/BRPI0720472A2/pt not_active IP Right Cessation
- 2007-12-21 MY MYPI20092582A patent/MY146557A/en unknown
- 2007-12-21 ES ES07851703.4T patent/ES2496166T3/es active Active
- 2007-12-21 KR KR1020070135270A patent/KR100954828B1/ko active IP Right Grant
- 2007-12-21 ZA ZA200905094A patent/ZA200905094B/xx unknown
- 2007-12-21 WO PCT/KR2007/006738 patent/WO2008078922A1/en active Application Filing
- 2007-12-21 EP EP07851703.4A patent/EP2101737B1/en not_active Not-in-force
- 2007-12-21 JP JP2009542655A patent/JP5484910B2/ja not_active Expired - Fee Related
- 2007-12-21 CA CA002673536A patent/CA2673536A1/en not_active Abandoned
- 2007-12-21 MX MX2009006105A patent/MX2009006105A/es unknown
- 2007-12-21 RU RU2009128206/15A patent/RU2461382C2/ru not_active IP Right Cessation
-
2008
- 2008-06-13 PA PA20088784701A patent/PA8784701A1/es unknown
- 2008-06-18 SA SA8290368A patent/SA08290368B1/ar unknown
- 2008-06-20 PE PE2008001062A patent/PE20090424A1/es not_active Application Discontinuation
- 2008-06-20 AR ARP080102637A patent/AR067084A1/es not_active Application Discontinuation
- 2008-06-20 TW TW097123092A patent/TW200927124A/zh unknown
-
2010
- 2010-05-28 HK HK10105215.6A patent/HK1138517A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SA08290368B1 (ar) | 2011-10-08 |
EP2101737A1 (en) | 2009-09-23 |
MY146557A (en) | 2012-08-30 |
TW200927124A (en) | 2009-07-01 |
MX2009006105A (es) | 2009-06-18 |
EP2101737B1 (en) | 2014-06-18 |
US20100041688A1 (en) | 2010-02-18 |
CA2673536A1 (en) | 2008-07-03 |
AU2007339080B2 (en) | 2012-09-27 |
CN101600419A (zh) | 2009-12-09 |
PE20090424A1 (es) | 2009-05-15 |
ZA200905094B (en) | 2010-09-29 |
KR20080059083A (ko) | 2008-06-26 |
KR100954828B1 (ko) | 2010-04-27 |
JP5484910B2 (ja) | 2014-05-07 |
AR067084A1 (es) | 2009-09-30 |
JP2010513474A (ja) | 2010-04-30 |
RU2009128206A (ru) | 2011-01-27 |
AU2007339080A1 (en) | 2008-07-03 |
RU2461382C2 (ru) | 2012-09-20 |
EP2101737A4 (en) | 2013-05-01 |
WO2008078922A1 (en) | 2008-07-03 |
HK1138517A1 (en) | 2010-08-27 |
CN101600419B (zh) | 2012-05-09 |
ES2496166T3 (es) | 2014-09-18 |
BRPI0720472A2 (pt) | 2014-01-14 |
US8663658B2 (en) | 2014-03-04 |
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