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PA8663901A1 - Derivados del (1,5-difenil-1h-pirazol-3-il)oxadiazol, su prepararacion y su aplicacion en terapéutica - Google Patents

Derivados del (1,5-difenil-1h-pirazol-3-il)oxadiazol, su prepararacion y su aplicacion en terapéutica

Info

Publication number
PA8663901A1
PA8663901A1 PA20068663901A PA8663901A PA8663901A1 PA 8663901 A1 PA8663901 A1 PA 8663901A1 PA 20068663901 A PA20068663901 A PA 20068663901A PA 8663901 A PA8663901 A PA 8663901A PA 8663901 A1 PA8663901 A1 PA 8663901A1
Authority
PA
Panama
Prior art keywords
difenil
pirazol
oxadiazol
therapeutics
derivatives
Prior art date
Application number
PA20068663901A
Other languages
English (en)
Inventor
Francis Barth
Christian Congy
Patrick Gueule
Murielle Rinaldi-Carmona
Broeck Didier Van
Original Assignee
Sanofi Aventis Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8663901(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Sanofi Aventis filed Critical Sanofi Aventis Sanofi Aventis
Publication of PA8663901A1 publication Critical patent/PA8663901A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)

Abstract

LA PRESENTE INVENCION TINE COMO OBJETIVO COMPUESTOS QYE RESPONDEN A LA FORMULA: EN LA QUE: RI REPRESENTA UN RADICAL HETEROCICLICO ELEGIDO ENTRE: R2 REPRESENTA UN ALQUILO (C1-C5) O UN CIANO; R3 REPRESENTA UN FENILO NO SUSTITUIDO O SUSTITUIDO; R4 REPRESENTA UN FENILO NO SUSTITUIDO O SUSTITUIDO; ASI COMO SUS HIDRATOS O SUS SOLVATOS.
PA20068663901A 2005-02-21 2006-02-21 Derivados del (1,5-difenil-1h-pirazol-3-il)oxadiazol, su prepararacion y su aplicacion en terapéutica PA8663901A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0501860A FR2882365B1 (fr) 2005-02-21 2005-02-21 Derives de 2-(1,5-diphenyl-1h-pyrazol-3-yl)-1,3,4-oxadiazole leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
PA8663901A1 true PA8663901A1 (es) 2006-12-07

Family

ID=35079215

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20068663901A PA8663901A1 (es) 2005-02-21 2006-02-21 Derivados del (1,5-difenil-1h-pirazol-3-il)oxadiazol, su prepararacion y su aplicacion en terapéutica

Country Status (25)

Country Link
US (1) US7632852B2 (es)
EP (1) EP1853595A1 (es)
JP (1) JP4812778B2 (es)
KR (1) KR20070107053A (es)
CN (1) CN101119990A (es)
AR (1) AR055560A1 (es)
AU (1) AU2006215443A1 (es)
BR (1) BRPI0606845A2 (es)
CA (1) CA2597359A1 (es)
DO (1) DOP2006000045A (es)
EA (1) EA200701779A1 (es)
FR (1) FR2882365B1 (es)
GT (1) GT200600082A (es)
IL (1) IL185163A0 (es)
MA (1) MA29261B1 (es)
MX (1) MX2007009994A (es)
NO (1) NO20074763L (es)
NZ (1) NZ560790A (es)
PA (1) PA8663901A1 (es)
PE (1) PE20061038A1 (es)
SV (1) SV2007002422A (es)
TW (1) TW200640916A (es)
UY (1) UY29388A1 (es)
WO (1) WO2006087480A1 (es)
ZA (1) ZA200706953B (es)

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BRPI0715160A2 (pt) 2006-08-08 2013-06-11 Sanofi Aventis imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso
US7875647B2 (en) 2006-09-29 2011-01-25 Green Cross Corporation Heteroaryl-pyrazole derivatives as cannabinoid CB1 receptor antagonists
CN101528740B (zh) * 2006-09-29 2012-09-19 株式会社绿十字 作为大麻素cb1受体拮抗剂的杂芳基-吡唑衍生物
US20080207704A1 (en) * 2007-02-27 2008-08-28 The Green Cross Corporation Heteroaryl-imidazole derivatives as cannabinoid cb1 receptor antagonists
US7705024B2 (en) 2007-04-12 2010-04-27 National Health Research Institutes Oxadiazole compounds
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2009078498A1 (en) * 2007-12-17 2009-06-25 Green Cross Corporation Biarylpyrazole 4-carboxamides as cannabinoid cb1 receptor ligands
WO2010003624A2 (en) 2008-07-09 2010-01-14 Sanofi-Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010035915A1 (en) * 2008-09-25 2010-04-01 Green Cross Corporation Sulfur containing pyrazole-heterocycle derivatives as cannabinoid cb1 receptor antagonists
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
BR112012003973A2 (pt) 2009-08-26 2015-09-08 Sanofi Sa hidratos de fluoroglicosídeo heteroaromático cristalinos, produtos farmacêuticos compreendendo estes compostos e seu uso
EP2582709B1 (de) 2010-06-18 2018-01-24 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
WO2012120054A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8901114B2 (en) 2011-03-08 2014-12-02 Sanofi Oxathiazine derivatives substituted with carbocycles or heterocycles, method for producing same, drugs containing said compounds, and use thereof
WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683700B1 (de) 2011-03-08 2015-02-18 Sanofi Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120055A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
CN109651350B (zh) * 2019-01-11 2022-05-24 贵州大学 一类杂环取代的1,3,4-噁(噻)二唑类化合物及其制备方法和用途
CN109942567B (zh) * 2019-04-30 2023-04-07 贵州大学 一种1,3,4-噁(噻)二唑基的咪唑类化合物及其制备方法和用途

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BR0316332A (pt) * 2002-12-02 2005-09-27 Astellas Pharma Inc Composto pirazólico, composição farmacêutica e agente analgésico contendo o mesmo, processo para sua preparação e seu uso e pacote comercial
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MA29261B1 (fr) 2008-02-01
US7632852B2 (en) 2009-12-15
TW200640916A (en) 2006-12-01
AU2006215443A1 (en) 2006-08-24
FR2882365B1 (fr) 2007-09-07
PE20061038A1 (es) 2006-11-24
SV2007002422A (es) 2007-01-17
EP1853595A1 (fr) 2007-11-14
FR2882365A1 (fr) 2006-08-25
KR20070107053A (ko) 2007-11-06
GT200600082A (es) 2006-10-19
NO20074763L (no) 2007-11-16
UY29388A1 (es) 2006-10-02
NZ560790A (en) 2009-08-28
EA200701779A1 (ru) 2008-02-28
ZA200706953B (en) 2009-03-25
BRPI0606845A2 (pt) 2009-07-21
CN101119990A (zh) 2008-02-06
CA2597359A1 (fr) 2006-08-24
IL185163A0 (en) 2007-12-03
WO2006087480A1 (fr) 2006-08-24
JP4812778B2 (ja) 2011-11-09
MX2007009994A (es) 2007-10-10
US20080039510A1 (en) 2008-02-14
AR055560A1 (es) 2007-08-22
JP2008530188A (ja) 2008-08-07

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