LU92903I2 - Gardasil-9/nom du produit:protéine hpv 52 l1 - Google Patents
Gardasil-9/nom du produit:protéine hpv 52 l1 Download PDFInfo
- Publication number
- LU92903I2 LU92903I2 LU92903C LU92903C LU92903I2 LU 92903 I2 LU92903 I2 LU 92903I2 LU 92903 C LU92903 C LU 92903C LU 92903 C LU92903 C LU 92903C LU 92903 I2 LU92903 I2 LU 92903I2
- Authority
- LU
- Luxembourg
- Prior art keywords
- gardasil
- product name
- protein hpv
- hpv
- protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/045—Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55592604P | 2004-03-24 | 2004-03-24 | |
PCT/US2005/009199 WO2005097821A1 (en) | 2004-03-24 | 2005-03-18 | Optimized expression of hpv 52 l1 in yeast |
EP05725933A EP1730175B1 (en) | 2004-03-24 | 2005-03-18 | Optimized expression of hpv 52 l1 in yeast |
Publications (1)
Publication Number | Publication Date |
---|---|
LU92903I2 true LU92903I2 (fr) | 2016-03-08 |
Family
ID=34964085
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LU92903C LU92903I2 (fr) | 2004-03-24 | 2015-12-08 | Gardasil-9/nom du produit:protéine hpv 52 l1 |
Country Status (31)
Country | Link |
---|---|
US (2) | US7700103B2 (el) |
EP (1) | EP1730175B1 (el) |
JP (1) | JP4833962B2 (el) |
KR (1) | KR101203403B1 (el) |
CN (1) | CN1934131B (el) |
AR (1) | AR048191A1 (el) |
AT (1) | ATE466022T1 (el) |
AU (1) | AU2005230907C1 (el) |
BE (1) | BE2015C066I2 (el) |
BR (1) | BRPI0509079B8 (el) |
CA (1) | CA2560487C (el) |
CY (2) | CY1110349T1 (el) |
DE (1) | DE602005020913D1 (el) |
DK (1) | DK1730175T3 (el) |
ES (1) | ES2343255T3 (el) |
FR (1) | FR15C0085I2 (el) |
HU (1) | HUS1500062I1 (el) |
IL (1) | IL178140A (el) |
LT (2) | LTPA2015050I1 (el) |
LU (1) | LU92903I2 (el) |
MY (1) | MY148656A (el) |
NL (1) | NL300777I1 (el) |
NO (3) | NO338055B1 (el) |
NZ (1) | NZ549898A (el) |
PL (1) | PL1730175T3 (el) |
PT (1) | PT1730175E (el) |
RU (1) | RU2373219C2 (el) |
SI (1) | SI1730175T1 (el) |
TW (1) | TWI349036B (el) |
WO (1) | WO2005097821A1 (el) |
ZA (1) | ZA200607575B (el) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7858098B2 (en) * | 2002-12-20 | 2010-12-28 | Glaxosmithkline Biologicals, S.A. | Vaccine |
CN1869215B (zh) * | 2006-05-19 | 2012-07-04 | 长春百克生物科技股份公司 | 一种制备人乳头瘤病毒的病毒样颗粒的方法 |
CA2679720A1 (en) | 2007-03-09 | 2008-09-18 | Merck & Co., Inc. | Papillomavirus vaccine compositions |
CN101835797A (zh) | 2007-11-23 | 2010-09-15 | 上海泽润生物科技有限公司 | 人乳头状瘤病毒主要衣壳蛋白l1基因及其用途 |
CN101440371B (zh) * | 2007-11-23 | 2012-09-05 | 上海泽润生物科技有限公司 | 一种16型人乳头状瘤病毒主要衣壳蛋白l1基因 |
PL2569008T3 (pl) * | 2010-05-14 | 2021-04-19 | Baxalta Incorporated | Chimery ospa i ich zastosowanie w szczepionkach |
CA2799205A1 (en) | 2010-05-25 | 2011-12-01 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
BR112013000031A2 (pt) * | 2010-07-02 | 2016-05-10 | Xiamen Innovax Biotech Co Ltd | proteína l1 hpv52 truncada ou variante da mesma, ácido nucleíco isolado, vetor, célula hospedeira, partícula do tipo viral hpv52, composição, composição farmacêutica ou vacina, método para obter uma proteína l1 hpv52 truncada, método para preparar a partícula do tipo viral hpv52, método para preparar uma vacina, método para prevenir a infecção hpv ou uma doença causada pela infecção de hpv e uso da proteína l1 hpv52 truncada ou variante da mesma |
US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
CN103562392B (zh) | 2010-12-03 | 2016-07-20 | Ms技术有限责任公司 | 植物细胞中草甘膦抗性编码核酸分子的优化表达 |
CN102154325B (zh) * | 2011-01-01 | 2013-08-21 | 上海生物制品研究所有限责任公司 | 针对人乳头瘤状病毒的疫苗及其制法和用途 |
RU2445357C1 (ru) * | 2011-02-15 | 2012-03-20 | Закрытое акционерное общество научно-производственная компания "Комбиотех" | Рекомбинантный штамм дрожжей pichia angusta - продуцент капсидного белка l1 вируса папилломы человека типа 16 |
RU2445358C1 (ru) * | 2011-02-15 | 2012-03-20 | Закрытое акционерное общество научно-производственная компания "Комбиотех" | Рекомбинантный штамм дрожжей pichia angusta - продуцент капсидного белка l1 вируса папилломы человека типа 18 |
CN110484554B (zh) * | 2013-04-26 | 2024-04-16 | 北京安百胜生物科技有限公司 | 用汉逊酵母表达系统产生hpv52 l1蛋白的方法 |
CN110592133A (zh) * | 2013-05-17 | 2019-12-20 | 北京安百胜生物科技有限公司 | 用汉逊酵母表达系统产生hpv31 l1蛋白的方法 |
WO2015057541A1 (en) | 2013-10-16 | 2015-04-23 | Merck Sharp & Dohme Corp. | Method of obtaining thermostable dried vaccine formulations |
CN104878022A (zh) * | 2015-04-27 | 2015-09-02 | 段青姣 | 编码hpv58l1、hpv52l1蛋白的核苷酸序列及其应用 |
CN106701796B (zh) * | 2015-08-12 | 2021-11-16 | 北京康乐卫士生物技术股份有限公司 | 52型重组人乳头瘤病毒病毒样颗粒及其制备方法 |
CN109750049B (zh) * | 2017-11-07 | 2023-08-18 | 上海泽润生物科技有限公司 | 重组人乳头瘤病毒52亚型蛋白表达 |
CA3166256A1 (en) | 2020-02-14 | 2021-08-19 | Marian E. Gindy | Human papillomavirus (hpv) virus-like particles (vlps) vaccine |
CN114539365B (zh) * | 2020-11-26 | 2023-12-01 | 中国医学科学院基础医学研究所 | 一种改造的人乳头瘤病毒52型l1蛋白及其用途 |
CN113073105B (zh) * | 2021-03-23 | 2023-06-13 | 重庆博唯佰泰生物制药有限公司 | 一种表达hpv 56l1的多核苷酸序列及其表达载体、宿主细胞和应用 |
CN113549634B (zh) * | 2021-06-07 | 2023-03-31 | 郑州大学 | 编码可溶性hpv58 l1蛋白的基因及其重组质粒的构建与应用 |
US20230048144A1 (en) | 2021-08-06 | 2023-02-16 | Merck Sharp & Dohme Llc | Hpv vaccine |
AR126813A1 (es) | 2021-08-19 | 2023-11-15 | Merck Sharp & Dohme Llc | Nueva nanopartícula lipídica termostable y métodos de uso de la misma |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1339729C (en) * | 1988-10-26 | 1998-03-17 | Wayne D. Lancaster | Human papillomavirus type 52 dna sequences and methods for employing thesame |
IL117591A0 (en) * | 1995-03-30 | 1996-07-23 | Merck & Co Inc | Synthetic DNA encoding human papillomavirus type 11 L1 protein |
US5821087A (en) * | 1995-03-30 | 1998-10-13 | Merck & Co., Inc. | Production of recombinant human papillomavirus type II protein utilizing papillomavirus 6/11 hybrid DNA |
IL131131A0 (en) | 1997-02-07 | 2001-01-28 | Merck & Co Inc | Synthetic hiv gag genes |
CA2296067C (en) | 1997-07-09 | 2008-10-07 | The University Of Queensland | Nucleic acid sequence and method for selectively expressing a protein in a target cell or tissue |
JP4563582B2 (ja) | 1998-08-14 | 2010-10-13 | メルク・シャープ・エンド・ドーム・コーポレイション | ヒトパピローマウイルスのウイルス様粒子を使用するタンパク質送達系 |
WO2000009671A1 (en) * | 1998-08-14 | 2000-02-24 | Merck & Co., Inc. | Process for purifying human papillomavirus virus-like particles |
SE514982C2 (sv) * | 1999-09-30 | 2001-05-28 | Active Biotech Ab | Bärare innehållande ett huvudkapsidprotein L1 från humant papillomavirus samt dess användning |
EP1212358B1 (en) | 1999-08-25 | 2004-12-15 | Merck & Co., Inc. | Synthetic papillomavirus genes optimized for expression in human cells |
US6436402B1 (en) | 1999-10-15 | 2002-08-20 | Merck & Co., Inc. | Process for making human papillomavirus virus-like particles with improved properties |
HUP0300745A3 (en) | 2000-07-21 | 2010-01-28 | Glaxo Group Ltd | Codon-optimized papilloma virus sequences |
US20030226155A1 (en) * | 2001-08-30 | 2003-12-04 | Biorexis Pharmaceutical Corporation | Modified transferrin-antibody fusion proteins |
NZ542246A (en) * | 2003-03-24 | 2007-12-21 | Merck & Co Inc | Optimized expression of HPV 31 L1 yeast |
MY140664A (en) | 2003-09-29 | 2010-01-15 | Merck Sharp & Dohme | Optimized expression of hpv 45 l1 in yeast |
MY139500A (en) | 2003-11-12 | 2009-10-30 | Merck Sharp & Dohme | Optimized expression of hpv 58 l1 in yeast |
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2005
- 2005-03-18 US US10/594,064 patent/US7700103B2/en active Active
- 2005-03-18 DK DK05725933.5T patent/DK1730175T3/da active
- 2005-03-18 DE DE602005020913T patent/DE602005020913D1/de active Active
- 2005-03-18 BR BRPI0509079A patent/BRPI0509079B8/pt active IP Right Grant
- 2005-03-18 ES ES05725933T patent/ES2343255T3/es active Active
- 2005-03-18 RU RU2006137363/13A patent/RU2373219C2/ru active
- 2005-03-18 AU AU2005230907A patent/AU2005230907C1/en active Active
- 2005-03-18 PL PL05725933T patent/PL1730175T3/pl unknown
- 2005-03-18 EP EP05725933A patent/EP1730175B1/en active Active
- 2005-03-18 JP JP2007505032A patent/JP4833962B2/ja active Active
- 2005-03-18 SI SI200531052T patent/SI1730175T1/sl unknown
- 2005-03-18 KR KR1020067019673A patent/KR101203403B1/ko active IP Right Grant
- 2005-03-18 TW TW094108431A patent/TWI349036B/zh active
- 2005-03-18 CN CN2005800095956A patent/CN1934131B/zh active Active
- 2005-03-18 MY MYPI20051180A patent/MY148656A/en unknown
- 2005-03-18 NZ NZ549898A patent/NZ549898A/en unknown
- 2005-03-18 AT AT05725933T patent/ATE466022T1/de active
- 2005-03-18 WO PCT/US2005/009199 patent/WO2005097821A1/en active Application Filing
- 2005-03-18 CA CA2560487A patent/CA2560487C/en active Active
- 2005-03-18 PT PT05725933T patent/PT1730175E/pt unknown
- 2005-03-23 AR ARP050101174A patent/AR048191A1/es active IP Right Grant
-
2006
- 2006-09-11 ZA ZA200607575A patent/ZA200607575B/xx unknown
- 2006-09-17 IL IL178140A patent/IL178140A/en active IP Right Grant
- 2006-10-23 NO NO20064815A patent/NO338055B1/no active Protection Beyond IP Right Term
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2009
- 2009-10-14 US US12/578,995 patent/US7744892B2/en active Active
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2010
- 2010-07-26 CY CY20101100698T patent/CY1110349T1/el unknown
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2015
- 2015-11-30 NL NL300777C patent/NL300777I1/nl unknown
- 2015-12-02 HU HUS1500062C patent/HUS1500062I1/hu unknown
- 2015-12-04 FR FR15C0085C patent/FR15C0085I2/fr active Active
- 2015-12-07 CY CY2015052C patent/CY2015052I1/el unknown
- 2015-12-08 LT LTPA2015050D patent/LTPA2015050I1/lt unknown
- 2015-12-08 LU LU92903C patent/LU92903I2/xx unknown
- 2015-12-08 LT LTPA2015050C patent/LTC1730175I2/lt unknown
- 2015-12-09 BE BE2015C066C patent/BE2015C066I2/nl unknown
-
2017
- 2017-01-20 NO NO2017005C patent/NO2017005I1/no unknown
-
2022
- 2022-11-30 NO NO2022050C patent/NO2022050I1/no unknown
Also Published As
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