LT3250239T - Kapsidė - Google Patents
KapsidėInfo
- Publication number
- LT3250239T LT3250239T LTEP16721917.9T LT16721917T LT3250239T LT 3250239 T LT3250239 T LT 3250239T LT 16721917 T LT16721917 T LT 16721917T LT 3250239 T LT3250239 T LT 3250239T
- Authority
- LT
- Lithuania
- Prior art keywords
- capsid
- Prior art date
Links
- 210000000234 capsid Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1508026.0A GB201508026D0 (en) | 2015-05-11 | 2015-05-11 | Capsid |
| PCT/GB2016/051329 WO2016181123A1 (en) | 2015-05-11 | 2016-05-10 | Capsid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3250239T true LT3250239T (lt) | 2019-03-25 |
Family
ID=53489438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP16721917.9T LT3250239T (lt) | 2015-05-11 | 2016-05-10 | Kapsidė |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US10414803B2 (lt) |
| EP (2) | EP3250239B1 (lt) |
| JP (2) | JP6619454B2 (lt) |
| KR (1) | KR20180019543A (lt) |
| CN (1) | CN107864653B (lt) |
| AU (1) | AU2016261454B2 (lt) |
| CA (1) | CA2985945C (lt) |
| DK (1) | DK3250239T3 (lt) |
| ES (1) | ES2711349T3 (lt) |
| GB (1) | GB201508026D0 (lt) |
| HR (1) | HRP20190442T1 (lt) |
| HU (1) | HUE042693T2 (lt) |
| LT (1) | LT3250239T (lt) |
| PL (1) | PL3250239T3 (lt) |
| PT (1) | PT3250239T (lt) |
| TR (1) | TR201901582T4 (lt) |
| TW (1) | TW201704253A (lt) |
| WO (1) | WO2016181123A1 (lt) |
Families Citing this family (30)
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| GB201420139D0 (en) | 2014-11-12 | 2014-12-24 | Ucl Business Plc | Factor IX gene therapy |
| GB201508026D0 (en) * | 2015-05-11 | 2015-06-24 | Ucl Business Plc | Capsid |
| IL299901B1 (en) | 2015-09-28 | 2024-08-01 | Univ Florida | Methods and compositions for stealth virus antibody vectors |
| GB201608046D0 (en) | 2016-05-09 | 2016-06-22 | Cambridge Entpr Ltd And Syndey Children S Hospitals Network Randwick And Westmead Incorporating The | Treatment of complement-mediated disorders |
| CN111511375A (zh) * | 2017-06-30 | 2020-08-07 | 因提玛生物科学公司 | 用于基因治疗的腺相关病毒载体 |
| JP7378417B2 (ja) * | 2018-03-30 | 2023-11-13 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 増強されたヒト膵臓トロピズムを有する新規な組換えアデノ随伴ウイルスキャプシド |
| KR20210007963A (ko) | 2018-04-03 | 2021-01-20 | 스트라이드바이오 인코포레이티드 | 항체-회피 바이러스 벡터 |
| JP7425738B2 (ja) | 2018-04-03 | 2024-01-31 | ギンコ バイオワークス インコーポレイテッド | 眼組織を標的とするウイルスベクター |
| CA3094311A1 (en) | 2018-04-03 | 2019-10-10 | Stridebio, Inc. | Antibody-evading virus vectors |
| US10842885B2 (en) | 2018-08-20 | 2020-11-24 | Ucl Business Ltd | Factor IX encoding nucleotides |
| KR102114249B1 (ko) | 2018-08-21 | 2020-05-22 | 코나아이 (주) | 가상 화폐 결제 방법 및 시스템 |
| GB201817810D0 (en) | 2018-10-31 | 2018-12-19 | Ucl Business Plc | Modified factor IX polypeptides |
| AU2020241888A1 (en) | 2019-03-21 | 2021-09-30 | Ginkgo Bioworks, Inc. | Recombinant adeno-associated virus vectors |
| EP3715358A1 (en) * | 2019-03-28 | 2020-09-30 | Universität zu Köln | Mutated adeno-associated virus capsid proteins, aav particle comprising the same and liver directed aav vector gene therapy |
| US20220162642A1 (en) | 2019-04-12 | 2022-05-26 | Freeline Therapeutics Limited | Plasmid system |
| PL3722434T3 (pl) | 2019-04-12 | 2022-12-12 | Freeline Therapeutics Limited | Układ plazmidowy |
| US20220265853A1 (en) * | 2019-07-12 | 2022-08-25 | Gene Therapy Research Institution Co., Ltd. | Adeno-associated virus virion for gene transfer to human liver |
| AU2020330121A1 (en) * | 2019-08-14 | 2022-03-03 | University Of Florida Research Foundation, Incorporated | AAV capsid variants for gene therapy |
| US20220380413A1 (en) * | 2019-08-29 | 2022-12-01 | The Board Of Trustees Of The Leland Stanford Junior University | Adeno-Associated Viral Vectors for Crossing the Human Blood Brain Barrier |
| TW202128736A (zh) | 2019-10-17 | 2021-08-01 | 美商史崔德生物公司 | 用於治療ｃ型尼曼—匹克病之腺相關病毒載體 |
| MX2022010388A (es) * | 2020-02-25 | 2022-12-13 | Childrens Medical Res Institute | Polipéptidos de la cápside y vectores de virus adenoasociado. |
| WO2022003211A1 (en) * | 2020-07-03 | 2022-01-06 | Genethon | Method for engineering novel hybrid aav capsids through hypervariable regions swapping |
| JP2023542614A (ja) | 2020-08-19 | 2023-10-11 | サレプタ セラピューティクス， インコーポレイテッド | レット症候群の治療のためのアデノ随伴ウイルスベクター |
| GB202016254D0 (en) | 2020-10-13 | 2020-11-25 | Freeline Therapeutics Ltd | Plasmid system |
| CN113121654B (zh) * | 2021-04-19 | 2023-11-17 | 信念医药科技(上海)有限公司 | 腺相关病毒衣壳蛋白及包含其的腺相关病毒载体 |
| WO2022226301A1 (en) * | 2021-04-23 | 2022-10-27 | The University Of North Carolina At Chapel Hill | Chimeric heart tropic aav capsids |
| GB202109231D0 (en) | 2021-06-25 | 2021-08-11 | Freeline Therapeutics Ltd | Promoter |
| CN118201947A (zh) * | 2021-10-28 | 2024-06-14 | 上海天泽云泰生物医药有限公司 | 腺相关病毒衣壳 |
| GB202205514D0 (en) | 2022-04-13 | 2022-05-25 | Freeline Therapeutics Ltd | Mechanical lysis |
| GB202214328D0 (en) | 2022-09-29 | 2022-11-16 | Freeline Therapeutics Ltd | Method |
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| JP2020518259A (ja) | 2017-05-05 | 2020-06-25 | ボイジャー セラピューティクス インコーポレイテッドＶｏｙａｇｅｒ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | ハンチントン病治療組成物および方法 |
| CA3066358A1 (en) | 2017-06-07 | 2018-12-13 | Spark Therapeutics, Inc. | Enhancing agents for improved cell transfection and/or raav vector production |
| JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
| CN111032176A (zh) | 2017-06-30 | 2020-04-17 | 星火治疗有限公司 | Aav载体柱纯化方法 |
| KR20200036912A (ko) | 2017-07-31 | 2020-04-07 | 리플렉션 바이오테크놀러지스 리미티드 | 안과 질환을 위한 세포 모델 및 치료요법 |
| JP7499174B2 (ja) | 2017-08-01 | 2024-06-13 | スパーク セラピューティクス インコーポレイテッド | 第ｖｉｉｉ因子（ｆｖｉｉｉ）遺伝子治療法 |
| WO2019028306A2 (en) | 2017-08-03 | 2019-02-07 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR ADMINISTRATION OF ADENO-ASSOCIATED VIRUSES |
| WO2019043081A1 (en) | 2017-08-29 | 2019-03-07 | Ruprecht-Karls-Universität Heidelberg | RATIONALLY DESIGNED PSEUDOVIRAL PARTICLES FOR THE MODULATION OF CHIMERIC ANTIGENIC RECEPTOR (CAR) T CELL THERAPY |
| EP3684388A4 (en) | 2017-09-22 | 2021-09-22 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF HUNTINGTON'S DISEASE |
| US12123027B2 (en) | 2017-10-12 | 2024-10-22 | Ascend Advanced Therapies Limited | Life-cycle-defective adenovirus helper viruses, their production and use for producing rAAV |
-
2015
- 2015-05-11 GB GBGB1508026.0A patent/GB201508026D0/en not_active Ceased
-
2016
- 2016-05-10 WO PCT/GB2016/051329 patent/WO2016181123A1/en active Application Filing
- 2016-05-10 CA CA2985945A patent/CA2985945C/en active Active
- 2016-05-10 PL PL16721917T patent/PL3250239T3/pl unknown
- 2016-05-10 CN CN201680027100.0A patent/CN107864653B/zh active Active
- 2016-05-10 KR KR1020177035515A patent/KR20180019543A/ko not_active Application Discontinuation
- 2016-05-10 ES ES16721917T patent/ES2711349T3/es active Active
- 2016-05-10 EP EP16721917.9A patent/EP3250239B1/en active Active
- 2016-05-10 JP JP2017558723A patent/JP6619454B2/ja active Active
- 2016-05-10 PT PT16721917T patent/PT3250239T/pt unknown
- 2016-05-10 DK DK16721917.9T patent/DK3250239T3/en active
- 2016-05-10 US US15/573,350 patent/US10414803B2/en active Active
- 2016-05-10 AU AU2016261454A patent/AU2016261454B2/en active Active
- 2016-05-10 TR TR2019/01582T patent/TR201901582T4/tr unknown
- 2016-05-10 EP EP18210522.1A patent/EP3511021A1/en active Pending
- 2016-05-10 LT LTEP16721917.9T patent/LT3250239T/lt unknown
- 2016-05-10 HU HUE16721917A patent/HUE042693T2/hu unknown
- 2016-05-11 TW TW105114580A patent/TW201704253A/zh unknown
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2019
- 2019-03-05 HR HRP20190442TT patent/HRP20190442T1/hr unknown
- 2019-11-14 JP JP2019206191A patent/JP2020096587A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2018520997A (ja) | 2018-08-02 |
| PL3250239T3 (pl) | 2019-05-31 |
| US20180111965A1 (en) | 2018-04-26 |
| JP2020096587A (ja) | 2020-06-25 |
| WO2016181123A1 (en) | 2016-11-17 |
| GB201508026D0 (en) | 2015-06-24 |
| CN107864653B (zh) | 2022-06-21 |
| EP3250239B1 (en) | 2018-12-12 |
| CA2985945A1 (en) | 2016-11-17 |
| US10414803B2 (en) | 2019-09-17 |
| EP3511021A1 (en) | 2019-07-17 |
| AU2016261454A1 (en) | 2017-11-23 |
| KR20180019543A (ko) | 2018-02-26 |
| PT3250239T (pt) | 2019-02-19 |
| US20200079821A1 (en) | 2020-03-12 |
| EP3250239A1 (en) | 2017-12-06 |
| TW201704253A (zh) | 2017-02-01 |
| CN107864653A (zh) | 2018-03-30 |
| ES2711349T3 (es) | 2019-05-03 |
| HUE042693T2 (hu) | 2019-07-29 |
| HRP20190442T1 (hr) | 2019-05-03 |
| JP6619454B2 (ja) | 2019-12-11 |
| TR201901582T4 (tr) | 2019-02-21 |
| AU2016261454B2 (en) | 2019-07-11 |
| DK3250239T3 (en) | 2019-03-11 |
| CA2985945C (en) | 2022-09-06 |
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