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LT3129400T - Gyvūnai, išskyrus žmogų, turintys humanizuotus fc-gama receptorius - Google Patents

Gyvūnai, išskyrus žmogų, turintys humanizuotus fc-gama receptorius

Info

Publication number
LT3129400T
LT3129400T LTEP15718060.5T LT15718060T LT3129400T LT 3129400 T LT3129400 T LT 3129400T LT 15718060 T LT15718060 T LT 15718060T LT 3129400 T LT3129400 T LT 3129400T
Authority
LT
Lithuania
Prior art keywords
humanized
human animals
gamma receptors
receptors
gamma
Prior art date
Application number
LTEP15718060.5T
Other languages
English (en)
Inventor
Andrew J. Murphy
Lynn Macdonald
Cagan Gurer
Karolina A. Meagher
Naxin Tu
Original Assignee
Regeneron Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharmaceuticals, Inc. filed Critical Regeneron Pharmaceuticals, Inc.
Publication of LT3129400T publication Critical patent/LT3129400T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/072—Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0387—Animal model for diseases of the immune system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTEP15718060.5T 2014-04-08 2015-04-08 Gyvūnai, išskyrus žmogų, turintys humanizuotus fc-gama receptorius LT3129400T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461977037P 2014-04-08 2014-04-08
PCT/US2015/024920 WO2015157415A1 (en) 2014-04-08 2015-04-08 Non-human animals having humanized fc-gamma receptors

Publications (1)

Publication Number Publication Date
LT3129400T true LT3129400T (lt) 2020-06-25

Family

ID=52997579

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15718060.5T LT3129400T (lt) 2014-04-08 2015-04-08 Gyvūnai, išskyrus žmogų, turintys humanizuotus fc-gama receptorius

Country Status (23)

Country Link
US (4) US9474255B2 (lt)
EP (2) EP3129400B1 (lt)
JP (2) JP6652931B2 (lt)
KR (2) KR102223264B1 (lt)
CN (2) CN111690052B (lt)
AU (2) AU2015243865C1 (lt)
CA (1) CA2935472C (lt)
CY (1) CY1123046T1 (lt)
DK (1) DK3129400T3 (lt)
ES (1) ES2794942T3 (lt)
HR (1) HRP20200899T1 (lt)
HU (1) HUE051088T2 (lt)
IL (2) IL246497B (lt)
LT (1) LT3129400T (lt)
MX (1) MX2016013241A (lt)
PH (1) PH12016501341A1 (lt)
PL (1) PL3129400T3 (lt)
PT (1) PT3129400T (lt)
RS (1) RS60398B1 (lt)
RU (2) RU2019128394A (lt)
SG (2) SG11201604886WA (lt)
SI (1) SI3129400T1 (lt)
WO (1) WO2015157415A1 (lt)

Families Citing this family (12)

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NO2785538T3 (lt) 2014-05-07 2018-08-04
EP3157956B1 (en) 2014-06-19 2020-02-05 Regeneron Pharmaceuticals, Inc. Non-human animals having a humanized programmed cell death 1 gene
BR112017010793A2 (pt) 2014-11-24 2017-12-26 Regeneron Pharma animal não humano geneticamente modificado, camundongo, métodos para produzir um animal não humano geneticamente modificado e de triagem de candidatos a fármaco direcionados a um antígeno de interesse, e, modelo de camundongo.
CA2967834C (en) 2014-12-05 2024-01-16 Regeneron Pharmaceuticals, Inc. Non-human animals having a humanized cluster of differentiation 47 gene
AU2015360667B2 (en) 2014-12-09 2021-09-23 Regeneron Pharmaceuticals, Inc. Non-human animals having a humanized cluster of differentiation 274 gene
ES2872799T3 (es) 2015-11-20 2021-11-02 Regeneron Pharma Animales no humanos que tienen un gen 3 de activación linfocitaria humanizado
AU2017228293B2 (en) 2016-02-29 2023-05-25 Regeneron Pharmaceuticals, Inc. Rodents having a humanized Tmprss gene
CN111655031B (zh) 2017-11-30 2022-11-18 瑞泽恩制药公司 包含人源化trkb基因座的非人动物
EP3772926A1 (en) * 2018-03-26 2021-02-17 Regeneron Pharmaceuticals, Inc. Humanized rodents for testing therapeutic agents
EP3823443B1 (en) 2018-07-16 2024-05-22 Regeneron Pharmaceuticals, Inc. Rodent models of ditra disease and uses thereof
CA3199879A1 (en) 2020-12-16 2022-06-23 Regeneron Pharmaceuticals, Inc. Mice expressing humanized fc alpha receptors

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FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
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CA2507882A1 (en) 2002-12-16 2004-07-22 Genentech, Inc. Transgenic mice expressing human cd20
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RU2019128394A (ru) * 2014-04-08 2019-10-07 Регенерон Фармасьютикалз, Инк. Не относящиеся к человеку животные, имеющие гуманизированные fc-гамма-рецепторы

Also Published As

Publication number Publication date
RU2016143036A (ru) 2018-05-08
DK3129400T3 (da) 2020-06-08
IL264364A (en) 2019-02-28
PT3129400T (pt) 2020-05-27
RU2016143036A3 (lt) 2018-10-24
IL246497B (en) 2019-06-30
EP3129400A1 (en) 2017-02-15
CN111690052B (zh) 2024-06-04
CY1123046T1 (el) 2021-10-29
KR20160142309A (ko) 2016-12-12
CN111690052A (zh) 2020-09-22
CN106163273B (zh) 2020-07-24
JP6652931B2 (ja) 2020-02-26
EP3129400B1 (en) 2020-03-25
IL264364B (en) 2021-03-25
SI3129400T1 (sl) 2020-07-31
AU2020217312A1 (en) 2020-08-27
AU2020217312B2 (en) 2023-04-13
JP6858283B2 (ja) 2021-04-14
AU2015243865A1 (en) 2016-08-18
JP2020062051A (ja) 2020-04-23
RU2700484C2 (ru) 2019-09-17
MX2016013241A (es) 2017-05-03
IL246497A0 (en) 2016-08-31
KR102223264B1 (ko) 2021-03-09
RU2019128394A (ru) 2019-10-07
HRP20200899T1 (hr) 2020-09-04
WO2015157415A1 (en) 2015-10-15
SG11201604886WA (en) 2016-07-28
PH12016501341A1 (en) 2016-08-15
AU2020217312C1 (en) 2023-10-26
ES2794942T3 (es) 2020-11-19
US9474255B2 (en) 2016-10-25
US20170086432A1 (en) 2017-03-30
US20230232795A1 (en) 2023-07-27
AU2015243865B2 (en) 2020-05-14
CA2935472A1 (en) 2015-10-15
JP2017510285A (ja) 2017-04-13
KR20210024249A (ko) 2021-03-04
HUE051088T2 (hu) 2021-03-01
SG10201908800YA (en) 2019-11-28
US11503812B2 (en) 2022-11-22
PL3129400T3 (pl) 2020-09-07
CA2935472C (en) 2024-02-20
RS60398B1 (sr) 2020-07-31
US10555507B2 (en) 2020-02-11
CN106163273A (zh) 2016-11-23
US20200288684A1 (en) 2020-09-17
EP3693383A1 (en) 2020-08-12
AU2015243865C1 (en) 2020-11-26
KR102439412B1 (ko) 2022-09-02
US20150282463A1 (en) 2015-10-08

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