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LT2922541T - Piridilo hidrazonai, skirti tuberkuliozės ir susijusių ligų gydymui - Google Patents

Piridilo hidrazonai, skirti tuberkuliozės ir susijusių ligų gydymui

Info

Publication number
LT2922541T
LT2922541T LTEP13811632.2T LT13811632T LT2922541T LT 2922541 T LT2922541 T LT 2922541T LT 13811632 T LT13811632 T LT 13811632T LT 2922541 T LT2922541 T LT 2922541T
Authority
LT
Lithuania
Prior art keywords
hydrazones
tuberculosis
pyridyl
treatment
related diseases
Prior art date
Application number
LTEP13811632.2T
Other languages
English (en)
Inventor
Ana Lucia Almeida Ferreira
Ana Sofia LOPES
Augusto Eugénio PARDAL FILIPE
Carlos CAIXADO
Pedro Filipe Eufrasio Pedroso
Susana Marques DE ALMEIDA PECORELLI
Original Assignee
Tecnimede-Sociedade Tecnico-Medicinal, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede-Sociedade Tecnico-Medicinal, S.A. filed Critical Tecnimede-Sociedade Tecnico-Medicinal, S.A.
Publication of LT2922541T publication Critical patent/LT2922541T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/76Nitrogen atoms to which a second hetero atom is attached
    • C07D213/77Hydrazine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTEP13811632.2T 2012-11-20 2013-11-20 Piridilo hidrazonai, skirti tuberkuliozės ir susijusių ligų gydymui LT2922541T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT106652A PT106652A (pt) 2012-11-20 2012-11-20 Piridil hidrazonas para o tratamento de tuberculose e doenças relacionadas
PCT/PT2013/000068 WO2014081324A1 (en) 2012-11-20 2013-11-20 Pyridyl hydrazones for the treatment of tuberculosis and related diseases

Publications (1)

Publication Number Publication Date
LT2922541T true LT2922541T (lt) 2019-09-25

Family

ID=49876952

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP13811632.2T LT2922541T (lt) 2012-11-20 2013-11-20 Piridilo hidrazonai, skirti tuberkuliozės ir susijusių ligų gydymui
LTEP19167996.8T LT3539543T (lt) 2012-11-20 2013-11-20 Piridilo hidrazonai, skirti tuberkuliozei ir su ja susijusioms ligoms gydyti

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP19167996.8T LT3539543T (lt) 2012-11-20 2013-11-20 Piridilo hidrazonai, skirti tuberkuliozei ir su ja susijusioms ligoms gydyti

Country Status (15)

Country Link
US (1) US9593103B2 (lt)
EP (2) EP2922541B1 (lt)
BR (1) BR112015011606A2 (lt)
CY (2) CY1121861T1 (lt)
DK (1) DK2922541T3 (lt)
ES (2) ES2899437T3 (lt)
HR (2) HRP20211767T1 (lt)
HU (2) HUE045502T2 (lt)
LT (2) LT2922541T (lt)
MA (1) MA38206B1 (lt)
PL (2) PL3539543T3 (lt)
PT (3) PT106652A (lt)
RS (2) RS62579B1 (lt)
SI (2) SI3539543T1 (lt)
WO (1) WO2014081324A1 (lt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115590857B (zh) * 2021-07-08 2024-11-05 中国医学科学院药物研究所 化合物t0349在制备抗结核分枝杆菌药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3716131A1 (de) * 1987-05-14 1988-12-01 Forsch Borstel Inst Fuer Exper Substituierte 2-acylpyridin-(alpha)-(n)-hetarylhydrazone sowie diese enthaltende arzneimittel
US8865901B2 (en) * 2009-10-02 2014-10-21 Fred Hutchinson Cancer Research Center Gain-of-function Bcl-2 inhibitors
EP2311457A1 (en) * 2009-10-19 2011-04-20 Forschungszentrum Borstel Pharmaceutical compositions for treating infections with drug resistant mycobacteria

Also Published As

Publication number Publication date
RS62579B1 (sr) 2021-12-31
ES2899437T3 (es) 2022-03-11
PT3539543T (pt) 2021-11-22
HUE056531T2 (hu) 2022-02-28
SI2922541T1 (sl) 2019-10-30
EP3539543B1 (en) 2021-09-01
CY1124836T1 (el) 2022-11-25
LT3539543T (lt) 2021-12-27
HUE045502T2 (hu) 2019-12-30
US9593103B2 (en) 2017-03-14
EP3539543A1 (en) 2019-09-18
PT106652A (pt) 2014-05-20
BR112015011606A2 (pt) 2017-07-11
MA38206B1 (fr) 2019-03-29
HRP20191402T1 (hr) 2019-11-15
ES2741434T3 (es) 2020-02-11
EP2922541A1 (en) 2015-09-30
DK2922541T3 (da) 2019-08-12
HRP20211767T1 (hr) 2022-02-18
EP2922541B1 (en) 2019-05-22
US20150284374A1 (en) 2015-10-08
CY1121861T1 (el) 2020-07-31
MA38206A1 (fr) 2017-12-29
PL3539543T3 (pl) 2022-01-10
RS59224B1 (sr) 2019-10-31
WO2014081324A1 (en) 2014-05-30
PT2922541T (pt) 2019-08-26
PL2922541T3 (pl) 2019-10-31
SI3539543T1 (sl) 2022-01-31

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