KR970027075A - Separation method of optical isomer - Google Patents
Separation method of optical isomer Download PDFInfo
- Publication number
- KR970027075A KR970027075A KR1019950042186A KR19950042186A KR970027075A KR 970027075 A KR970027075 A KR 970027075A KR 1019950042186 A KR1019950042186 A KR 1019950042186A KR 19950042186 A KR19950042186 A KR 19950042186A KR 970027075 A KR970027075 A KR 970027075A
- Authority
- KR
- South Korea
- Prior art keywords
- acid
- separation method
- optical isomer
- separating
- optically active
- Prior art date
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
본 발명은 광학이성질체의 분리방법에 관한 것으로서, 더욱 상세하게는 (±)-3-(2-N, N-디메틸아미노에틸)-2-(3-피리딜)-티아졸리딘-4-온 라세미 화합물에 타르타르산 또는 캄포술폰산 등의 광학활성 산를 반응시켜 부분 입체이성질체 염(diastereomer salt)을 얻은 다음, 알칼리 수용액으로 추출하고 산용액으로 중화한 후 재결정하여 광학 이성질체를 분리하는 방법에 관한 것이다.The present invention relates to a method for separating the optical isomers, and more particularly, (±) -3- (2-N, N-dimethylaminoethyl) -2- (3-pyridyl) -thiazolidin-4-one The present invention relates to a method for separating optical isomers by reacting a racemic compound with an optically active acid such as tartaric acid or camphorsulfonic acid to obtain a diastereomer salt, followed by extraction with an aqueous alkali solution, neutralization with an acid solution, and recrystallization.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019950042186A KR970027075A (en) | 1995-11-20 | 1995-11-20 | Separation method of optical isomer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019950042186A KR970027075A (en) | 1995-11-20 | 1995-11-20 | Separation method of optical isomer |
Publications (1)
Publication Number | Publication Date |
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KR970027075A true KR970027075A (en) | 1997-06-24 |
Family
ID=66588507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019950042186A KR970027075A (en) | 1995-11-20 | 1995-11-20 | Separation method of optical isomer |
Country Status (1)
Country | Link |
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KR (1) | KR970027075A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58103386A (en) * | 1981-12-11 | 1983-06-20 | Sumitomo Chem Co Ltd | Optically active aminoalcohol derivative and its preparation |
JPH01279882A (en) * | 1987-05-22 | 1989-11-10 | Sumitomo Pharmaceut Co Ltd | Novel thiazolidine-4-one derivative and acid addition salt thereof |
JPH0429990A (en) * | 1990-05-24 | 1992-01-31 | Sumitomo Pharmaceut Co Ltd | Production of optically active cis-thiazolidin-4-one derivative |
-
1995
- 1995-11-20 KR KR1019950042186A patent/KR970027075A/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58103386A (en) * | 1981-12-11 | 1983-06-20 | Sumitomo Chem Co Ltd | Optically active aminoalcohol derivative and its preparation |
JPH01279882A (en) * | 1987-05-22 | 1989-11-10 | Sumitomo Pharmaceut Co Ltd | Novel thiazolidine-4-one derivative and acid addition salt thereof |
JPH0429990A (en) * | 1990-05-24 | 1992-01-31 | Sumitomo Pharmaceut Co Ltd | Production of optically active cis-thiazolidin-4-one derivative |
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