KR970001206B1 - Capsule cosmetics comprising liquid crystal - Google Patents

Abstract

The prescription for the composition comprises in wt % : (1) cholesteryl ester liquid crystal in proper wt%; (2) guanine pearl 0.02; (3) agar aqueous solution 1.5; (4) carboxal vinyl polymer 0.5; (5) glycerine10.0; (6) hyaluronic acid 5.0; (7) allantoin 1.0; (8) butylene glycol; (9) triethanolamine 0.5; (10) aloe extract 3.0; (11) ethanol 5.0; (12) perfume in a proper amount; (13) antiseptic agent proper amount; (14) purified water to 100. The composition is prepared by dispersing guanine pearl pigment 0.02% and cholesteryl ester liquid crystal uniformly in agar 1.5 % aqueous solution for the resulting mixture to be extrude through a duplex nozzle to be dropped into a fluidal coolant flow to form agar coated capsules of grain size 1- 2 mm in diameter. The produced capsules are added to a hydrophillic dispersant medium of the above-mentioned prescription to produce the composition.

Description

Liquid crystal-containing capsule cosmetics

1 shows the product of the present invention and the conventional product effect on oxygen induced red blood cell hemolysis.

The present invention relates to a capsule cosmetic containing a liquid crystal. In particular, the present invention is excellent in water retention, and by adding a pearl or oil-soluble pigment to the liquid crystal with a change in color with temperature changes, the aesthetic effect is better when using only the liquid crystal alone, and also lipophilic to dissolve the pigment The present invention relates to a capsule cosmetic composition comprising evenly dispersing and mixing a capsule in a hydrophilic dispersion medium by preparing a seamless capsule using agar as a wall material containing oil-soluble skin active substances in a solvent.

Among the many organic substances showing liquid crystal properties, the cholesteryl ester-based liquid crystal is suitable for cosmetics in consideration of color change and skin stability due to temperature change, and the liquid crystal has good affinity for biological tissue and excellent moisturizing effect. It can also have a protective effect.

In the manufacturing method of Japanese Patent Application Laid-open No. Hei 2-223506, liquid crystal cosmetics were prepared by dispersing a liquid crystal of a cholesteryl ester system having moisture holding ability in a transparent or translucent cosmetic, and looking at the manufacturing method of Japanese Patent Laid-Open No. 3-240714. Cosmetics containing cholesteryl ester liquid crystal and conchiorine hydrolyzate were prepared, and the method of Japanese Patent Application Laid-open No. 3-49886 was prepared by combining oleic acid, lauryl acid and cholesteryl ester liquid crystal to make a liquid crystal compound transparent or translucent. It is a method for producing a cosmetic by dispersing in.

However, these methods are too difficult to produce the desired formulation in the manufacture of cosmetics because the viscosity of the liquid crystal is too high, and the problem occurs because of the difference between the oil phase component and the water phase component when the cosmetic composition is an oil phase. . In particular, the use of a surfactant is likely to cause side effects on the skin, even in trace amounts.

In addition, the manufacturing method of Japanese Patent Application Laid-open No. 3-240175 shows that the cholesteryl ester liquid crystal is microencapsulated and dispersed in a transparent or translucent cosmetic, which has characteristics specific to liquid crystals, but liquid crystals alone have limitations in displaying color and are required by cosmetics. In the case of manufacturing cosmetics by encapsulating a mixture of cholesteryl ester liquid crystal and lactic acid and dispersing it in cosmetics, the lactic acid provides nutrition to the cells. The removal of the causative harmful oxygen is not easy, and low pH lactic acid, which is not neutralized, can cause severe side effects on inactivation of the enzyme system and dermatitis.

On the other hand, in cosmetics manufacturing, most of lipophilic substances are excellent in skin moisturizing effect and excellent in preventing skin aging, and these substances are problematic in stability of cosmetics because they are mixed with a large amount of substances which are oxidized and denatured upon contact with air. Was difficult to formulate into cosmetics, or it was difficult to blend at all, depending on the material, these materials are not soluble in water to prepare a cosmetic using a surfactant, but even a small amount of common surfactants irritate the skin It can act as a provoking factor and cause problems in stability even when manufactured as a product.

Until now, the addition of pearl or pigment and oil to liquid crystals has not been easily conceived since the liquid crystals themselves have color and tend to lose their properties by oils.

The present invention solves the above-mentioned problems in dispersing liquid crystals in cosmetics and develops a color suitable for cosmetics while encapsulating the liquid crystals so as not to use a surfactant that may cause side effects of the skin at all. To prepare a liquid crystal mixture in which pearl or pigment was added to the liquid crystal, a capsule was prepared. In this manner, the color is very beautiful due to synergy by mixing liquid crystal with pearl or dye. At this time, it is preferable to add 0.01-2.0 weight part of pearls and 0.01-5.0 weight part of pigments with respect to liquid crystal amount. In addition, the capsule cosmetics that have excellent color removal and excellent effect on the skin are prepared by simultaneously mixing components with excellent removal ability of harmful oxygen and excellent whitening effect to give skin activity, and dispersing and stabilizing them in hydrophilic ingredients. To prepare. At this time, the amount of oil is preferably used in the minimum amount necessary to mix the oil-soluble pigment and the skin active substance, it is preferable to use 0.01 to 5.0 parts by weight based on the amount of liquid crystal.

The cholesteryl ester-based liquid crystals suitable for cosmetics include cholesteryl nonanoate, cholesteryl cinnamate, cholesteryl benzoate, cholesteryl adipate, cholesteryl palmitate, cholesteryl oleate, and cholesterol. Yl stearate, cholesteryl propionate, cholesteryl oleyl carbonate, cholesteryl isosdearyl carbonate, and the like. In the present invention, one or two or more of these cholesteryl ester-based liquid crystals are mixed. Can be used.

As the perl used in the present invention, guanine, higher fatty acids and derivatives thereof, and mica titanium pearls of various colors can be used. In particular, the pulmonary effect of pearl itself can be obtained by using mica titanium containing iron oxide compounds. Effects can also be given.

The oil-soluble dyes used in the present invention include red 218, red 225, orange 206, blue 204, green 204, β-carotene, siconin, and the like. The lipophilic skin active substances may be mixed and used as vitamin E acetate, vitamin A palmitate, chamomile extract, rosemary extract, evening primrose oil, royal jelly, tocopherol, squalene, squalane, jojoba oil, γ-orizanol and the like. In 1 type, 2 or more types of these active substances can be mix | blended and used.

The seamless capsule manufacturing method of the present invention comprises a core material in which the wall material of the capsule and the oil-soluble pigment, the skin active substance, and the liquid crystal are mixed in a predetermined ratio, and a mixture of the liquid crystal and pearl as the core material, respectively, with double nozzles. Submerged curing coating method was used in which a jet flow was formed at the tip of the double nozzle and the droplets formed around the core by the difference in the surface tension at the jet flow were dropped into the cooling liquid to form a spherical capsule.

The present invention will be described below with reference to examples.

Example 1

Manufacturing method

Seamless capsule consisting of agar film with a particle size of 1-2mm by extruding in a refrigerant flowing through a double nozzle with a content of 1.5% aqueous solution of agar as a wall and evenly dispersing guanine pearl 0.02% and cholesteryl ester liquid crystal. Was prepared. The prepared capsules were added to the evenly dispersed hydrophilic dispersion medium up to Formula 4-14 to prepare a cosmetic.

Example 2

Manufacturing method

Aqueous 2% aqueous solution of agar as a wall material, 0.5% of iron oxide-containing mica titanate and even amount of cholesteryl ester liquid crystal are evenly dispersed, and pressurized and discharged in a refrigerant flowing through a double nozzle to size 1-2.5mm in size. A seamless capsule made of agar was prepared. The prepared capsules were evenly dispersed in the evenly dispersed hydrophilic dispersion medium up to Formula 4-13 to prepare a cosmetic.

Example 3

Manufacturing method

Aqueous solution of 1.5% agar was used as a coating material, that is, a wall material, and evenly dispersed vitamin E acetate, 0.05% of red No. 225, and cholesteryl ester liquid crystal. To prepare a seamless capsule consisting of agar film consisting of 0.5-2.5mm agar and added to the evenly dispersed hydrophilic dispersion medium up to Formula 5-13 to prepare a cosmetic.

Example 4

Manufacturing method

A 2% aqueous agar solution is used as a wall material, and the core material with β-carotene, 1% of vitamin A acetate and cholesteryl ester liquid crystal is evenly discharged to the refrigerant flowing through the double nozzle to obtain a particle size of 0.5-2.5 mm. A cosmetic was prepared by preparing a seamless capsule and dispersing the prepared capsule in an evenly dispersed hydrophilic dispersion medium up to Formula 5-14.

Example 5

Manufacturing method

A core material of 2% agar solution as a wall and 5% of cholesteryl ester liquid crystal, Siconin, and royal jelly was evenly discharged through a double nozzle and dropped into a flowing refrigerant to cool and harden the particle size of 0.5-2.5. A seamless capsule of mm was prepared, and a cosmetic prepared by dispersing the capsule prepared in Example 1 in the hydrophilic dispersion medium up to Formula 6-15.

Example 6

Manufacturing method

A seamless capsule was prepared by pressurizing and ejecting a core material, which was evenly dispersed with guanine pearl 0.01%, red 218, γ-orizanol 1.5%, and cholesteryl ester liquid crystal to a refrigerant flowing through a double nozzle, using an aqueous solution of 2% agar as a wall material. And to prepare a cosmetics dispersed in the hydrophilic dispersion medium to the formulation 6-17 to the prepared capsule.

In order to measure the skin activation effect of the capsule prepared by Example 4 of the present invention, oxygen (O ₂ ) induced erythrocyte hemolysis was performed. Oxygen-induced erythrocyte hemolysis was performed by using Rose Bangal as a sensitizer and investigating the effect of the capsule on oxygen-induced erythrocyte hemolysis. Red blood cells were obtained from the semen of rabbits, washed with a solution of pH 2.4, and then experimented. Erythrocyte hemolysis was measured by change in absorbance at 700 mm at 15 min intervals. All experiments were performed in a constant temperature dark room at 25 ° C. The results of this experiment are shown in FIG.

As shown in FIG. 1, it can be seen that the liquid crystal, the oil-soluble liquid crystal, the oil-soluble oil, and the pigment-containing capsule (A) produced by the manufacturing method of the present invention are more effective in removing harmful oxygen than the capsule (B) of liquid crystal only.

Claims (1)

Cholesteryl Nonanoate, Cholesteryl Cinnamate, Cholesteryl Benzoate, Cholesteryl Adipate, Choleneryl Palmitate, Cholesteryl Linate, Cholesteryl Stearate, Cholesteryl Propionate, Cholesterol Group consisting of guanine pearl, higher fatty acid and its derivative pearl, mica titanium pearl and iron oxide-containing mica titanium mica in liquid crystal of cholesteryl ester system selected from the group consisting of steryl oleyl carbonate and cholesteryl isostearyl carbonate Pearl, or oil-soluble pigment selected from the group consisting of red 218, red 225, orange 206, blue 204, green 204, β-carotene and siconin, and vitamin E acetate, vitamin A palmitate, chamomile Extract, rosemary extract, evening primrose oil, royal jelly, tocopherol, squalene, squalane, jojoba oil and γ-orizanol A seamless capsule containing a mixture made by adding a lipophilic skin active substance selected from the group consisting of agar, agar containing agar, with a pearl content of 0.01 to 2.0 parts by weight based on the liquid crystal contained in the capsule, and a pigment content. A capsule cosmetic composition comprising 0.01 to 5.0 parts by weight based on the liquid crystal contained in the capsule, and containing 0.01 to 5.0 parts by weight based on the liquid crystal contained in the capsule.