KR960022578A - Sustained release antibacterial emulsion dispersion and preparation method thereof - Google Patents

Abstract

The present invention relates to a sustained-release antibacterial emulsion dispersion and a method for preparing the same, and more particularly, to form micropores in the interior of the particles when dried, and to provide a target material such as a bactericide in the same space of the particles. The present invention relates to a novel multi-stage emulsion polymerization method which significantly increases the effective duration of a target material by controlling the dissolution rate of the target material by the polymer shell to be contained, and an emulsion polymer dispersion prepared accordingly.

Description

Sustained release antibacterial emulsion dispersion and preparation method thereof

As this is a public information case, the full text was not included.

Claims (12)

Method for producing a sustained-release antibacterial emulsion dispersion comprising the following steps, 1) emulsion polymerization of core particles from an acid monomer having a carboxylic acid group, a general monomer and a monomer mixture containing a hydrophobic fungicide as a target material Making a step; 2) encapsulating the core particles with a hard coat by continuously emulsion polymerizing the envelope forming monomer in the presence of the core particles, and 3) swelling the resulting core-shell polymer particles with a base at an elevated temperature. Preparing a release controlled antibacterial emulsion dispersion having internal pores containing both pores and a target material therein after drying. The method of claim 1, wherein the core forming step comprises a single step or a plurality of steps including a seed preparation step. The method of claim 1, wherein the target material is a liquid which is insoluble in water and miscible with a monomer, or a solid which can be dissolved in a monomer and a solvent, and includes 2- (methoxycarbonylamino) benzimidazole, 2-4 , -Thiazolyl) -benzimidazole, 2,3,5,6-tetrachloro-4-methylsulfonipyridin, 2-n-octyl-4-isothiazolin-3-one, 2,4,5, 6-tetrachloroisophthalonitrile, N, N-dimethyl-N '-(fluorodichloromethylthio) -N'-sulfamide, zinc 2-pyridinethiol-1-oxide, diiodomethyl-P-tolyl-sulfone And 3-iodo-2-propazyl butylcarbamate N- (fluorodichloromethylthio) -phthalimide and the like for use in at least one selected. According to claim 1 or 3, wherein the target material is a method for producing a sustained-release antibacterial emulsion dispersion, characterized in that the weight ratio of the core monomer and the target material in the core forming step is 1: 0.5 to 1: 5. . The method of claim 4, wherein the target material is used by pre-emulsification with each monomer mixture. The method of claim 1, wherein the envelope forming step comprises a single or a plurality of steps. The method of claim 1 or 3, wherein the target material is used at 1 to 30% by weight of the shell forming monomer in the shell forming step. The method of claim 7, wherein the target material is used by pre-emulsification with each monomer mixture. The method of claim 1, wherein the step of neutralizing and swelling with the base is carried out after the final envelope forming step or in the middle of the plurality of envelope forming steps. The method of claim 1, wherein the weight ratio of the cell component to the core component is 1: 1 to 1:50. The method of claim 1, wherein the size of the various emulsion particles is 0.1-5.0 microns. A coating or impregnating composition containing 30% by weight or less of an emulsion polymer dispersion prepared by the method according to claim 1. ※ Note: The disclosure is based on the initial application.