KR950700297A - 5-HT3-수용체 길항제로서의 2,6-메타노-2H-퀴놀리진 유도체(2,6-Methano-2H-quinolizin derivative as 5-HT3-receptor antagonist) - Google Patents

5-HT3-수용체 길항제로서의 2,6-메타노-2H-퀴놀리진 유도체(2,6-Methano-2H-quinolizin derivative as 5-HT3-receptor antagonist)

Info

Publication number: KR950700297A
Authority: KR; South Korea
Prior art keywords: receptor antagonist; quinolizin; methano; derivative; antagonist
Prior art date: 1992-02-24

Application number

KR1019940702945A

Other languages

English (en)

Other versions

KR100287933B1 (ko

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-24

Filing date

1994-08-24

Publication date

1995-01-16

1993-02-03 Application filed filed Critical

1995-01-16 Publication of KR950700297A publication Critical patent/KR950700297A/ko

2001-05-02 Application granted granted Critical

2001-05-02 Publication of KR100287933B1 publication Critical patent/KR100287933B1/ko

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

KR1019940702945A 1992-02-24 1993-02-03 5-ht3-수용체 길항제로서의 2,6-메타노-2h-퀴놀리진 유도체,이의 제조방법 및 이를 포함하는 약제학적 조성물 KR100287933B1 (ko)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP92400474		1992-02-24
EP92400474.0		1992-02-24
PCT/US1993/000880 WO1993017019A1 (en)	1992-02-24	1993-02-03	2,6-methano-2h-quinolizin derivative as 5-ht3-receptor antagonist

Publications (2)

Publication Number	Publication Date
KR950700297A true KR950700297A (ko)	1995-01-16
KR100287933B1 KR100287933B1 (ko)	2001-05-02

Family

ID=8211614

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019940702945A KR100287933B1 (ko)	1992-02-24	1993-02-03	5-ht3-수용체 길항제로서의 2,6-메타노-2h-퀴놀리진 유도체,이의 제조방법 및 이를 포함하는 약제학적 조성물

Country Status (14)

Country	Link
EP (1)	EP0628043A1 (ko)
JP (1)	JPH07504192A (ko)
KR (1)	KR100287933B1 (ko)
AU (1)	AU675060B2 (ko)
CA (1)	CA2130563C (ko)
FI (1)	FI105917B (ko)
HU (1)	HU216831B (ko)
IL (1)	IL104821A (ko)
MX (1)	MX9300948A (ko)
NO (1)	NO943101L (ko)
NZ (1)	NZ249346A (ko)
TW (1)	TW226374B (ko)
WO (1)	WO1993017019A1 (ko)
ZA (1)	ZA931146B (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2672500A (en)	1999-02-18	2000-09-04	Novartis Ag	Systemic use of 5-ht3 receptor antagonists against rheumatic inflammatory processes
CN104248763A (zh)	2005-03-07	2014-12-31	芝加哥大学	阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途
US8518962B2 (en)	2005-03-07	2013-08-27	The University Of Chicago	Use of opioid antagonists
US9662325B2 (en)	2005-03-07	2017-05-30	The University Of Chicago	Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8524731B2 (en)	2005-03-07	2013-09-03	The University Of Chicago	Use of opioid antagonists to attenuate endothelial cell proliferation and migration

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2080727T3 (es) *	1988-02-23	1996-02-16	Merrell Pharma Inc	Uso de quinolizina y derivados de quinolizinona en la fabricacion de medicamentos.
EP0517984A1 (en) *	1991-06-11	1992-12-16	Merrell Dow Pharmaceuticals Inc.	Derivatives of amide analogs of certain methano bridged quinolizines

1993
- 1993-02-03 CA CA002130563A patent/CA2130563C/en not_active Expired - Lifetime
- 1993-02-03 HU HU9402436A patent/HU216831B/hu unknown
- 1993-02-03 KR KR1019940702945A patent/KR100287933B1/ko not_active IP Right Cessation
- 1993-02-03 AU AU36034/93A patent/AU675060B2/en not_active Expired
- 1993-02-03 JP JP5514868A patent/JPH07504192A/ja active Pending
- 1993-02-03 EP EP93904797A patent/EP0628043A1/en not_active Withdrawn
- 1993-02-03 NZ NZ249346A patent/NZ249346A/en not_active IP Right Cessation
- 1993-02-03 WO PCT/US1993/000880 patent/WO1993017019A1/en active IP Right Grant
- 1993-02-18 ZA ZA931146A patent/ZA931146B/xx unknown
- 1993-02-19 TW TW082101189A patent/TW226374B/zh not_active IP Right Cessation
- 1993-02-22 IL IL10482193A patent/IL104821A/xx not_active IP Right Cessation
- 1993-02-22 MX MX9300948A patent/MX9300948A/es unknown
1994
- 1994-08-23 FI FI943872A patent/FI105917B/fi not_active IP Right Cessation
- 1994-08-23 NO NO943101A patent/NO943101L/no unknown

Also Published As

Publication number	Publication date
AU675060B2 (en)	1997-01-23
HU9402436D0 (en)	1994-10-28
KR100287933B1 (ko)	2001-05-02
TW226374B (ko)	1994-07-11
AU3603493A (en)	1993-09-13
NO943101D0 (no)	1994-08-23
NZ249346A (en)	1995-10-26
HUT68249A (en)	1995-06-28
IL104821A (en)	1997-01-10
FI105917B (fi)	2000-10-31
HU216831B (hu)	1999-09-28
CA2130563A1 (en)	1993-09-02
CA2130563C (en)	1997-11-11
JPH07504192A (ja)	1995-05-11
FI943872A0 (fi)	1994-08-23
FI943872A (fi)	1994-08-23
IL104821A0 (en)	1993-06-10
NO943101L (no)	1994-08-23
WO1993017019A1 (en)	1993-09-02
EP0628043A1 (en)	1994-12-14
MX9300948A (es)	1993-08-01
ZA931146B (en)	1993-09-14

Publication	Publication Date	Title
NL300035I1 (nl)	2001-03-01	Gesubstitueerde thiahzolidinedionderivaten.
DK0680488T3 (da)	1999-01-25	2,6-Diaminopurinderivater
FI934610A0 (fi)	1993-10-19	Ventilsammansaettning foer roerledning, omfattande loestagbart ventilsaete
AT397656B (de)	1994-06-27	(6,7-substituierte-8-alkoxy-1-cyclopropyl-1,4-
DE69329894D1 (de)	2001-03-01	Arylamidderivate
FI932516A (fi)	1993-12-04	Styrkonsol, i synnerhet foer motorfordon
NO932842L (no)	1994-02-14	1,4-benzodioksanderivater
FI931747A (fi)	1993-10-18	Reflexkropp, isynnerhet foer vaegmarkeringar
NO920420D0 (no)	1992-01-31	3-quinuklidin-derivater
FI931451A0 (fi)	1993-03-31	7-oxo-7h-pyrido(1,2,3-de)(1,4)bensoxazin-6-karboxylsyror och -estrar
DE59308564D1 (de)	1998-06-25	2,4-Dialkyl-6-sec-alkylphenole
FI941149A (fi)	1994-12-22	2,4-diamino-3-hydroksikarboksyylihapon johdannaisia
KR950700297A (ko)	1995-01-16	5-HT3-수용체 길항제로서의 2,6-메타노-2H-퀴놀리진 유도체(2,6-Methano-2H-quinolizin derivative as 5-HT3-receptor antagonist)
FI940607A (fi)	1994-02-09	Imidatso(5,1-C)(1,4)bentsoksatsin-1-onijohdannaiset 5HT3-antagonisteina
FI950101A (fi)	1995-03-07	4-oksa-1-atsabisyklo 3,2,0 -7heptanoni-johdannaiset kasvainten vastaisina aineina
FI923542A (fi)	1993-02-08	Faestanordning foer klingor, isynnerhet i bestrykningsmaskiner
FI934317A (fi)	1994-04-03	Farmaceutiska sammansaettningar, vilka innehaoller ej-joniska ytaktiva aemnen
NO922732D0 (no)	1992-07-10	3,4-dehydropiperidinderivater
NO932638D0 (no)	1993-07-21	21-klor-pregnanderivat
NO944024D0 (no)	1994-10-21	1,2-dihydro-2-okso-pyridin
FI935130A0 (fi)	1993-11-19	Raelsbund vagn med skjuttak, saerskilt foer biltransport
FI266U1 (fi)	1992-09-16	Kapningsanordning foer aemnesbana, saosom en pappersbana
FI935129A (fi)	1994-05-27	Tvaovaoningsgodsvagn, saerskilt foer biltransport
NO943791D0 (no)	1994-10-07	1,2-dihydro-2-okso-3-metylsulfonylaminometylpyridin
NO942212D0 (no)	1994-06-13	13,14-dihydro-PGF2

Legal Events

Date	Code	Title	Description
1997-11-21	A201	Request for examination
1997-11-21	AMND	Amendment
1999-08-30	E902	Notification of reason for refusal
1999-11-30	AMND	Amendment
2000-03-15	E601	Decision to refuse application
2000-04-12	J201	Request for trial against refusal decision
2000-05-12	AMND	Amendment
2000-12-21	B701	Decision to grant
2001-02-01	GRNT	Written decision to grant
2013-01-17	FPAY	Annual fee payment	Payment date: 20130117 Year of fee payment: 13
2013-02-04	EXPY	Expiration of term