KR920021491A - 2-hydroxy-2-phenylethylamino compound - Google Patents
2-hydroxy-2-phenylethylamino compound Download PDFInfo
- Publication number
- KR920021491A KR920021491A KR1019920008404A KR920008404A KR920021491A KR 920021491 A KR920021491 A KR 920021491A KR 1019920008404 A KR1019920008404 A KR 1019920008404A KR 920008404 A KR920008404 A KR 920008404A KR 920021491 A KR920021491 A KR 920021491A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- formula
- pharmaceutically acceptable
- ethoxy
- acceptable salt
- Prior art date
Links
- -1 2-hydroxy-2-phenylethylamino compound Chemical class 0.000 title claims 3
- 150000001875 compounds Chemical class 0.000 claims 31
- 150000003839 salts Chemical class 0.000 claims 11
- 239000002243 precursor Substances 0.000 claims 10
- 125000001153 fluoro group Chemical group F* 0.000 claims 7
- 125000001309 chloro group Chemical group Cl* 0.000 claims 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 5
- 125000001246 bromo group Chemical group Br* 0.000 claims 4
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- IPBVNPXQWQGGJP-UHFFFAOYSA-N acetic acid phenyl ester Natural products CC(=O)OC1=CC=CC=C1 IPBVNPXQWQGGJP-UHFFFAOYSA-N 0.000 claims 2
- 229940049953 phenylacetate Drugs 0.000 claims 2
- 125000006239 protecting group Chemical group 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- ACUBPVISFFBSEO-KRWDZBQOSA-N 2-[4-[2-[[(2r)-2-hydroxy-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethoxy]phenyl]acetic acid Chemical compound C([C@H](O)C=1C=C(C=CC=1)C(F)(F)F)NCCOC1=CC=C(CC(O)=O)C=C1 ACUBPVISFFBSEO-KRWDZBQOSA-N 0.000 claims 1
- XNKRWZHRLBJGOA-UHFFFAOYSA-N 2-[4-[2-[[2-(3,5-difluorophenyl)-2-hydroxyethyl]amino]ethoxy]phenyl]acetic acid Chemical compound C=1C(F)=CC(F)=CC=1C(O)CNCCOC1=CC=C(CC(O)=O)C=C1 XNKRWZHRLBJGOA-UHFFFAOYSA-N 0.000 claims 1
- CMUURZOHLLJGBO-UHFFFAOYSA-N 2-[4-[2-[[2-(3-bromophenyl)-2-hydroxyethyl]amino]ethoxy]phenyl]acetic acid Chemical compound C=1C=CC(Br)=CC=1C(O)CNCCOC1=CC=C(CC(O)=O)C=C1 CMUURZOHLLJGBO-UHFFFAOYSA-N 0.000 claims 1
- ACZMITCMXCRGHQ-UHFFFAOYSA-N 2-[4-[2-[[2-(3-chlorophenyl)-2-hydroxyethyl]amino]ethoxy]phenyl]acetic acid Chemical compound C=1C=CC(Cl)=CC=1C(O)CNCCOC1=CC=C(CC(O)=O)C=C1 ACZMITCMXCRGHQ-UHFFFAOYSA-N 0.000 claims 1
- DIPOVEXYXYVYKV-UHFFFAOYSA-N 2-[4-[2-[[2-(3-fluorophenyl)-2-hydroxyethyl]amino]ethoxy]phenyl]acetic acid Chemical compound C=1C=CC(F)=CC=1C(O)CNCCOC1=CC=C(CC(O)=O)C=C1 DIPOVEXYXYVYKV-UHFFFAOYSA-N 0.000 claims 1
- QHSCMONKAODXQQ-UHFFFAOYSA-N 2-[4-[2-[[2-hydroxy-2-(3-methylphenyl)ethyl]amino]ethoxy]phenyl]acetic acid Chemical compound CC1=CC=CC(C(O)CNCCOC=2C=CC(CC(O)=O)=CC=2)=C1 QHSCMONKAODXQQ-UHFFFAOYSA-N 0.000 claims 1
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 208000035150 Hypercholesterolemia Diseases 0.000 claims 1
- 208000031226 Hyperlipidaemia Diseases 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 150000001735 carboxylic acids Chemical class 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 125000000524 functional group Chemical group 0.000 claims 1
- 239000008103 glucose Substances 0.000 claims 1
- 230000020169 heat generation Effects 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 208000006575 hypertriglyceridemia Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000035800 maturation Effects 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/22—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/06—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
- C07C251/08—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton being acyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/04—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C251/10—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
- C07C251/16—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- External Artificial Organs (AREA)
- Mechanical Coupling Of Light Guides (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
내용 없음No content
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.
Claims (17)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9111425.6 | 1991-05-28 | ||
| GB919111425A GB9111425D0 (en) | 1991-05-28 | 1991-05-28 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR920021491A true KR920021491A (en) | 1992-12-18 |
Family
ID=10695678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019920008404A KR920021491A (en) | 1991-05-28 | 1992-05-19 | 2-hydroxy-2-phenylethylamino compound |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0516350B1 (en) |
| JP (1) | JPH0687801A (en) |
| KR (1) | KR920021491A (en) |
| CN (1) | CN1069022A (en) |
| AT (1) | ATE128116T1 (en) |
| AU (1) | AU653229B2 (en) |
| CA (1) | CA2068378A1 (en) |
| CS (1) | CS159192A3 (en) |
| DE (1) | DE69204908T2 (en) |
| DK (1) | DK0516350T3 (en) |
| ES (1) | ES2077354T3 (en) |
| FI (1) | FI922423A (en) |
| GB (2) | GB9111425D0 (en) |
| GR (1) | GR3017681T3 (en) |
| HU (1) | HU211732B (en) |
| IE (1) | IE921446A1 (en) |
| IL (1) | IL101820A0 (en) |
| MW (1) | MW2392A1 (en) |
| MY (1) | MY137475A (en) |
| NO (1) | NO922114L (en) |
| NZ (1) | NZ242642A (en) |
| PL (1) | PL294705A1 (en) |
| RO (1) | RO111457B1 (en) |
| SI (1) | SI9200091A (en) |
| TW (1) | TW215917B (en) |
| YU (1) | YU54692A (en) |
| ZA (1) | ZA923355B (en) |
| ZW (1) | ZW7292A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0713698B1 (en) * | 1992-01-22 | 2002-04-03 | Glaxo Group Limited | Medical use of atypical beta-adrenoceptor agonists |
| GB9207964D0 (en) * | 1992-04-10 | 1992-05-27 | Ici Plc | Chemical compounds |
| US5480908A (en) * | 1993-12-13 | 1996-01-02 | American Cyanamid Company | β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions |
| US5541197A (en) * | 1994-04-26 | 1996-07-30 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| US5561142A (en) * | 1994-04-26 | 1996-10-01 | Merck & Co., Inc. | Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity |
| ES2094687B1 (en) * | 1994-08-02 | 1997-12-16 | S A L V A T Lab Sa | PHARMACEUTICAL COMBINATION AGAINST OBESITY OR OVERWEIGHT. |
| AU2710301A (en) * | 2000-01-28 | 2001-08-07 | Asahi Kasei Kabushiki Kaisha | Novel remedies with the use of beta3 agonist |
| US7709677B2 (en) | 2001-01-31 | 2010-05-04 | Glaxosmithkline Llc | Process of preparing arylethanoldiamines |
| GB0102407D0 (en) | 2001-01-31 | 2001-03-14 | Glaxo Group Ltd | Process |
| CN101544578B (en) * | 2009-03-24 | 2012-04-25 | 贵阳医学院 | phenylacetic acid derivatives, process for their preparation and their use in medicaments |
| CN103977015B (en) * | 2014-05-05 | 2016-10-05 | 南京瑞菁医药科技有限责任公司 | Chinese medicine saussurea intybus Lipid-lowering activities components compatibility compositions |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB212801A (en) * | 1923-06-18 | 1924-03-20 | Alfred George Osborne Strong | Improvements in machines for lining tins with paper bags |
| GB8519154D0 (en) * | 1985-07-30 | 1985-09-04 | Ici Plc | Aromatic ethers |
| GB2212801A (en) * | 1987-11-26 | 1989-08-02 | Resolution Chemicals Limited | Preparation of an alkanolamine derivatives |
| GB8910374D0 (en) * | 1989-05-05 | 1989-06-21 | Ici Plc | Chemical compounds |
-
1991
- 1991-05-28 GB GB919111425A patent/GB9111425D0/en active Pending
-
1992
- 1992-05-07 MW MW23/92A patent/MW2392A1/en unknown
- 1992-05-07 NZ NZ242642A patent/NZ242642A/en unknown
- 1992-05-08 ZA ZA923355A patent/ZA923355B/en unknown
- 1992-05-10 IL IL101820A patent/IL101820A0/en unknown
- 1992-05-11 ZW ZW72/92A patent/ZW7292A1/en unknown
- 1992-05-11 CA CA002068378A patent/CA2068378A1/en not_active Abandoned
- 1992-05-15 HU HU9201610A patent/HU211732B/en not_active IP Right Cessation
- 1992-05-19 KR KR1019920008404A patent/KR920021491A/en not_active Application Discontinuation
- 1992-05-21 AU AU17043/92A patent/AU653229B2/en not_active Ceased
- 1992-05-22 ES ES92304654T patent/ES2077354T3/en not_active Expired - Lifetime
- 1992-05-22 AT AT92304654T patent/ATE128116T1/en not_active IP Right Cessation
- 1992-05-22 DE DE69204908T patent/DE69204908T2/en not_active Expired - Fee Related
- 1992-05-22 EP EP92304654A patent/EP0516350B1/en not_active Expired - Lifetime
- 1992-05-22 DK DK92304654.4T patent/DK0516350T3/en active
- 1992-05-22 GB GB929210927A patent/GB9210927D0/en active Pending
- 1992-05-25 MY MYPI92000891A patent/MY137475A/en unknown
- 1992-05-25 YU YU54692A patent/YU54692A/en unknown
- 1992-05-26 CN CN92103976A patent/CN1069022A/en active Pending
- 1992-05-26 CS CS921591A patent/CS159192A3/en unknown
- 1992-05-27 NO NO92922114A patent/NO922114L/en unknown
- 1992-05-27 JP JP4134841A patent/JPH0687801A/en active Pending
- 1992-05-27 FI FI922423A patent/FI922423A/en not_active Application Discontinuation
- 1992-05-27 SI SI19929200091A patent/SI9200091A/en unknown
- 1992-05-27 PL PL29470592A patent/PL294705A1/en unknown
- 1992-05-28 RO RO92-200739A patent/RO111457B1/en unknown
- 1992-06-02 TW TW081104314A patent/TW215917B/zh active
- 1992-07-01 IE IE144692A patent/IE921446A1/en not_active Application Discontinuation
-
1995
- 1995-10-10 GR GR950402785T patent/GR3017681T3/en unknown
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