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KR920019752A - 2-클로로피리딘의 제조방법 - Google Patents

2-클로로피리딘의 제조방법 Download PDF

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Publication number
KR920019752A
KR920019752A KR1019920005513A KR920005513A KR920019752A KR 920019752 A KR920019752 A KR 920019752A KR 1019920005513 A KR1019920005513 A KR 1019920005513A KR 920005513 A KR920005513 A KR 920005513A KR 920019752 A KR920019752 A KR 920019752A
Authority
KR
South Korea
Prior art keywords
chloropyridine
process according
preparing
methylpyridine
reaction
Prior art date
Application number
KR1019920005513A
Other languages
English (en)
Other versions
KR100229177B1 (ko
Inventor
크람 귄터
린델 한스
스테판 기도
Original Assignee
만프레트 조벨, 요아힘 그렘
바이엘 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 만프레트 조벨, 요아힘 그렘, 바이엘 악티엔게젤샤프트 filed Critical 만프레트 조벨, 요아힘 그렘
Publication of KR920019752A publication Critical patent/KR920019752A/ko
Application granted granted Critical
Publication of KR100229177B1 publication Critical patent/KR100229177B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

내용 없음

Description

2-클로로피리딘의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 일반식(II)의 2-아미노피리딘 유도체를 -10 내지 +50℃의 온도에서, 염화수소를 동시에 도입시키면서 포화염산 수용액 중에서 니트로실 클로라이드와 반응시킴을 특징으로 하여 일반식(I)의 2-클로로피리딘 유도체를 제조하는 방법.
    상기식에서, R은 수소, C1-C4알킬 또는 할로겐을 나타내고, n은 0 내지 4이다.
  2. 제1항에 있어서, 반응을 0 내지 +20℃에서 수행함을 특징으로 하는 방법.
  3. 제1 또는 2항에 있어서, 반응 중에 부산물로서 생성된 피리돈을 공지의 방법으로 후처리하여 일반식(I)의 2-클로로피리딘 유도체를 수득함을 특징으로 하는 방법.
  4. 제1항 내지 제3항중의 어느 한 항에 있어서, 2-클로로-5-메틸피리딘을 2-아미노-5-메틸피리딘으로부터 제조함을 특징으로 하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019920005513A 1991-04-06 1992-04-02 2-클로로피리딘의 제조방법 KR100229177B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4111215.6 1991-04-06
DE4111215A DE4111215A1 (de) 1991-04-06 1991-04-06 Verfahren zur herstellung von 2-chlorpyridinen

Publications (2)

Publication Number Publication Date
KR920019752A true KR920019752A (ko) 1992-11-19
KR100229177B1 KR100229177B1 (ko) 1999-11-01

Family

ID=6428996

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920005513A KR100229177B1 (ko) 1991-04-06 1992-04-02 2-클로로피리딘의 제조방법

Country Status (7)

Country Link
US (1) US5283338A (ko)
EP (1) EP0508215B1 (ko)
JP (1) JP3046136B2 (ko)
KR (1) KR100229177B1 (ko)
DE (2) DE4111215A1 (ko)
ES (1) ES2086569T3 (ko)
TW (1) TW212173B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4322054A1 (de) * 1993-07-02 1995-01-12 Bayer Ag Verfahren zur Herstellung von Chlormethylpyridinen
DE4415337A1 (de) * 1994-05-02 1995-11-09 Bayer Ag Verfahren zur kontinuierlichen Herstellung von Nitrosylchlorid
JP3806529B2 (ja) * 1998-12-09 2006-08-09 株式会社日立グローバルストレージテクノロジーズ ロード・アンロード機構を備えた磁気ディスク装置
CN105037255B (zh) * 2015-07-16 2018-02-06 南京红太阳生物化学有限责任公司 一种2‑氯‑5‑甲基吡啶的合成方法
CN105061300B (zh) * 2015-08-31 2018-02-16 南京红太阳生物化学有限责任公司 一种氯代吡啶及其衍生物的合成方法
CN105622494B (zh) * 2015-10-15 2019-01-15 南京红太阳生物化学有限责任公司 一种2-氯-5-甲基吡啶的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL106957C (ko) * 1958-09-30
DE1178052B (de) * 1959-08-12 1964-09-17 Badische Anilin- &. Soda-Fabrik Aktiengesellschaft, Ludwigshafen/Rhein Verfahren zur Herstellung von heterocyclischen Verbindungne, die mindestens ein einem Ringstickstoffatom benachbartes Chloratom enthalten.
US3200040A (en) * 1961-03-22 1965-08-10 Hans Schwarzkopf Hair dye comprising diaminopyridines
DE1492175A1 (de) * 1965-07-07 1970-02-12 Schwarzkopf Gmbh Hans Verfahren zum Faerben von lebenden Haaren
CH501623A (de) * 1967-12-18 1971-01-15 Ruetgerswerke Ag Verfahren zur Herstellung von 2-Chlorpyridin und seinen Derivaten
DE1695659B1 (de) * 1967-12-18 1971-12-16 Ruetgerswerke Ag Verfahren zur Herstellung von 2-Chlorpyridinen
US4133675A (en) * 1976-07-23 1979-01-09 Ciba-Geigy Corporation Pyridyloxy-phenoxy-alkanecarboxylic acid derivatives which are effective as herbicides and as agents regulating plant growth
US4348396A (en) * 1978-01-23 1982-09-07 Hoffmann-La Roche Inc. Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them
US4404388A (en) * 1981-08-14 1983-09-13 Ciba-Geigy Corporation Process for producing 2-chloropyridines
GB8308822D0 (en) * 1983-03-30 1983-05-11 Ici Plc Chemical process
ZW5085A1 (en) * 1984-04-13 1985-09-18 Nihon Tokushu Noyaku Seizo Kk Nitromethylene derivatives,intermediates thereof,processes for production thereof,and insecticides
EP0178260B1 (de) * 1984-10-10 1990-05-16 Ciba-Geigy Ag Verfahren zur Herstellung von fluorierten Pyridin-Derivaten
DE3839332A1 (de) * 1988-11-22 1990-05-23 Bayer Ag Verfahren zur herstellung von substituierten 2-chlorpyridinen

Also Published As

Publication number Publication date
EP0508215A1 (de) 1992-10-14
EP0508215B1 (de) 1996-05-15
US5283338A (en) 1994-02-01
ES2086569T3 (es) 1996-07-01
TW212173B (ko) 1993-09-01
JPH05112529A (ja) 1993-05-07
DE59206271D1 (de) 1996-06-20
DE4111215A1 (de) 1992-10-08
JP3046136B2 (ja) 2000-05-29
KR100229177B1 (ko) 1999-11-01

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