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KR880012629A - 신규 리보푸라누론산 유도체 - Google Patents

신규 리보푸라누론산 유도체 Download PDF

Info

Publication number
KR880012629A
KR880012629A KR1019880003819A KR880003819A KR880012629A KR 880012629 A KR880012629 A KR 880012629A KR 1019880003819 A KR1019880003819 A KR 1019880003819A KR 880003819 A KR880003819 A KR 880003819A KR 880012629 A KR880012629 A KR 880012629A
Authority
KR
South Korea
Prior art keywords
deoxy
furinyl
alkyl
ribofuranuronic acid
ethylamide
Prior art date
Application number
KR1019880003819A
Other languages
English (en)
Korean (ko)
Inventor
가디엔트 풀비오
보겔 아놀드
Original Assignee
예안 클라메르,한스 루돌프 하우스
산도즈 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 예안 클라메르,한스 루돌프 하우스, 산도즈 리미티드 filed Critical 예안 클라메르,한스 루돌프 하우스
Publication of KR880012629A publication Critical patent/KR880012629A/ko

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019880003819A 1987-04-06 1988-04-04 신규 리보푸라누론산 유도체 KR880012629A (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
CHP3711562.6 1987-04-06
CHP3711563.4 1987-04-06
DE3711564 1987-04-06
DE3711561 1987-04-06
DE3711563 1987-04-06
CHP3711561.8 1987-04-06
CHP3711564.2 1987-04-06
DE3711562 1987-04-06

Publications (1)

Publication Number Publication Date
KR880012629A true KR880012629A (ko) 1988-11-28

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880003819A KR880012629A (ko) 1987-04-06 1988-04-04 신규 리보푸라누론산 유도체

Country Status (22)

Country Link
JP (1) JPS63258892A (fi)
KR (1) KR880012629A (fi)
AT (1) AT393507B (fi)
AU (1) AU609109B2 (fi)
BE (1) BE1002151A5 (fi)
CA (1) CA1326017C (fi)
CH (1) CH676121A5 (fi)
DK (1) DK183488A (fi)
ES (1) ES2007177A6 (fi)
FI (1) FI87463C (fi)
FR (1) FR2613367A1 (fi)
GB (1) GB2203149B (fi)
HU (1) HU201955B (fi)
IL (1) IL85969A (fi)
IT (1) IT1219892B (fi)
LU (1) LU87181A1 (fi)
MY (1) MY102323A (fi)
NL (1) NL8800862A (fi)
NZ (1) NZ224131A (fi)
PH (1) PH25424A (fi)
PT (1) PT87153B (fi)
SE (1) SE8801236L (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
CN1313861A (zh) 1998-06-23 2001-09-19 葛兰素集团有限公司 2-(嘌呤-9-基)-四氢呋喃-3,4-二醇衍生物
AR023463A1 (es) 1999-04-16 2002-09-04 Schering Corp Uso de compuestos de azetidinona
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
US7863253B2 (en) * 2004-09-20 2011-01-04 Inotek Pharmaceuticals Corporation Purine Derivatives and methods of use thereof
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
HU198950B (en) * 1986-12-15 1989-12-28 Sandoz Ag Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds
PT86660B (pt) * 1987-02-04 1992-02-28 Ciba Geigy Ag Processo para a preparacao de derivados de adenosina-5'-carboxamida

Also Published As

Publication number Publication date
NZ224131A (en) 1991-12-23
GB2203149B (en) 1991-02-13
SE8801236A0 (sv) 1988-10-17
FR2613367A1 (fr) 1988-10-07
SE8801236D0 (sv) 1988-04-05
FI881571A0 (fi) 1988-04-05
AT393507B (de) 1991-11-11
CA1326017C (en) 1994-01-11
JPS63258892A (ja) 1988-10-26
ATA87388A (de) 1991-04-15
GB8807750D0 (en) 1988-05-05
SE8801236L (sv) 1988-10-17
FI87463C (fi) 1993-01-11
LU87181A1 (fr) 1988-11-17
GB2203149A (en) 1988-10-12
HU201955B (en) 1991-01-28
AU609109B2 (en) 1991-04-26
IL85969A0 (en) 1988-09-30
IL85969A (en) 1992-03-29
PT87153A (pt) 1988-05-01
PT87153B (pt) 1992-07-31
PH25424A (fi) 1991-07-01
BE1002151A5 (fr) 1990-08-07
ES2007177A6 (es) 1989-06-01
IT1219892B (it) 1990-05-24
MY102323A (en) 1992-05-28
NL8800862A (nl) 1988-11-01
AU1415188A (en) 1988-10-06
FI881571A (fi) 1988-10-07
FI87463B (fi) 1992-09-30
DK183488A (da) 1988-10-07
DK183488D0 (da) 1988-04-05
IT8847794A0 (it) 1988-03-30
CH676121A5 (fi) 1990-12-14
HUT48902A (en) 1989-07-28

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Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application