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KR840008019A - 치환된 1,3-디아졸릴-2-프로판올의 제조방법 - Google Patents

치환된 1,3-디아졸릴-2-프로판올의 제조방법 Download PDF

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Publication number
KR840008019A
KR840008019A KR1019840001058A KR840001058A KR840008019A KR 840008019 A KR840008019 A KR 840008019A KR 1019840001058 A KR1019840001058 A KR 1019840001058A KR 840001058 A KR840001058 A KR 840001058A KR 840008019 A KR840008019 A KR 840008019A
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South Korea
Prior art keywords
alk
triazol
methyl
butanol
dimethyl
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KR1019840001058A
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English (en)
Inventor
엘베(외 5) 한스-루드비히
Original Assignee
칼 루드비히 슈미트, 귄터 슈마헤르
바이엘 아크 티엔게젤샤프트
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Application filed by 칼 루드비히 슈미트, 귄터 슈마헤르, 바이엘 아크 티엔게젤샤프트 filed Critical 칼 루드비히 슈미트, 귄터 슈마헤르
Publication of KR840008019A publication Critical patent/KR840008019A/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Coloring (AREA)

Abstract

내용 없음.

Description

치환된 1,3-디아졸릴-2-프로판올의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 일반식(Ⅱ)의 2-아졸릴-메틸-옥시란을 희석제존재하, 필요에 따라 염기 존재하에서 일반식(Ⅲ)의 아졸과 반응시킴을 특징으로 하여 일반식(I)의 치환된 1,3-디아졸릴-2-프로판올 및 생리학적으로 허용되는 이의 산 부가염을 제조하는 방법.
    상기식에서 ALK1는 직쇄 또는 측쇄 알킬이고 ALK2는 직쇄 또는 측쇄 알킬이거나, ALK1및 ALK2가 함께 시클로지방족 환이고, X는 질소원자 또는 CH기이고, Y는 질소원자 또는 CH기이고 R은 각기 임의 치환된 페닐, 페닐알킬, 페녹시, 페닐티오, 페녹시알킬, 페닐티오알킬, 벤질옥시 또는 벤질티오이다.
  2. 제1항에 있어서,4-(2,4-디클로로페닐)-3,3-디메틸-2-(1,2,4-트리아졸-1-일-메틸)-1-(1,2,4-트리아졸-1-일)-2-부탄올을 제조하는 방법.
  3. 제1항에 있어서, 4-(4-클로로페닐)-3,3-디메틸-2-(1,2,4-트리아졸-1-일-메틸)-1-(1,2,4-트리아졸-1-일)-2-부탄올을 제조하는 방법.
  4. 제1항에 있어서, 4-(4-메틸페닐)-3,3-디메틸-2-(1,2,4-트리아졸-1-일-메틸)-1-(1,2,4-트리아졸-1-일)-2-부탄올을 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840001058A 1983-03-02 1984-03-02 치환된 1,3-디아졸릴-2-프로판올의 제조방법 KR840008019A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833307217 DE3307217A1 (de) 1983-03-02 1983-03-02 Substituierte 1,3-diazolyl-2-propanole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
DEP3307217.5 1983-03-02

Publications (1)

Publication Number Publication Date
KR840008019A true KR840008019A (ko) 1984-12-12

Family

ID=6192202

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840001058A KR840008019A (ko) 1983-03-02 1984-03-02 치환된 1,3-디아졸릴-2-프로판올의 제조방법

Country Status (14)

Country Link
US (1) US4894382A (ko)
EP (1) EP0118070B1 (ko)
JP (1) JPS59164782A (ko)
KR (1) KR840008019A (ko)
AT (1) ATE22685T1 (ko)
AU (1) AU562292B2 (ko)
CA (1) CA1226579A (ko)
DE (2) DE3307217A1 (ko)
DK (1) DK83784A (ko)
ES (1) ES8504152A1 (ko)
GR (1) GR79547B (ko)
HU (1) HU191920B (ko)
IL (1) IL71099A (ko)
ZA (1) ZA841551B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3630129A1 (de) * 1986-09-04 1988-03-17 Bayer Ag Mercapto-substituierte hydroxyethyl-(triazol-1-yl)-derivate
DE4134125C2 (de) * 1991-10-15 1995-02-02 Mack Chem Pharm Triazol-Derivate enthaltende pharmazeutische Zusammensetzungen zur rektalen Applikation
CN105283450B (zh) 2013-04-12 2018-12-18 拜耳作物科学股份公司 三唑衍生物
US9550752B2 (en) 2013-04-12 2017-01-24 Bayer Cropscience Aktiengesellschaft Triazolinthione derivatives
WO2014167009A1 (en) 2013-04-12 2014-10-16 Bayer Cropscience Ag Novel triazole derivatives
BR112017021109A2 (pt) 2015-04-02 2018-07-03 Bayer Cropscience Ag derivados de triazol como fungicidas
MX2017012709A (es) 2015-04-02 2017-11-23 Bayer Cropscience Ag Nuevos derivados de imidazolilmetilo 5-sustituidos.
CA3036290A1 (en) 2016-09-13 2018-03-22 Bayer Cropscience Aktiengesellschaft Active compound combinations comprising a 5-substituted imidazole derivative
WO2018060074A1 (en) 2016-09-29 2018-04-05 Bayer Cropscience Aktiengesellschaft Novel 5-substituted imidazolylmethyl derivatives
EP3519392A1 (en) 2016-09-29 2019-08-07 Bayer CropScience Aktiengesellschaft Novel 5-substituted imidazole derivatives
US20200045972A1 (en) 2016-09-29 2020-02-13 Bayer Cropscience Aktiengesellschaft Novel 5-substituted imidazolylmethyl derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU542623B2 (en) * 1980-05-16 1985-02-28 Bayer Aktiengesellschaft 1-hydroxyethyl-azole derivatives
DE3018865A1 (de) * 1980-05-16 1981-11-26 Bayer Ag, 5090 Leverkusen Antimikrobielle mittel
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
ZA813354B (en) * 1980-06-02 1982-05-26 Ici Ltd Heterocyclic compounds
EP0061835B1 (en) * 1981-03-18 1989-02-01 Imperial Chemical Industries Plc Triazole compounds, a process for preparing them, their use as plant fungicides and fungicidal compositions containing them
DE3111238A1 (de) * 1981-03-21 1982-10-07 Bayer Ag, 5090 Leverkusen Substituierte triazolylmethyl-oxirane, verfahren zu ihrer herstellung sowie ihre verwendung als zwischenprodukte
EP0069442B1 (en) * 1981-06-06 1985-02-20 Pfizer Limited Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
GR78217B (ko) * 1981-07-02 1984-09-26 Ciba Geigy Ag
DE3202601A1 (de) * 1982-01-27 1983-08-04 Bayer Ag, 5090 Leverkusen Substituierte 1 -hydroxyalkyl-azolyl-derivate, verfahren zu ihrer herstellung sowie ihrer verwendung als fungizide und pflanzenwachstumsregulatoren
DE3232647A1 (de) * 1982-09-02 1984-03-08 Bayer Ag, 5090 Leverkusen Substituierte tert.-butanol-derivate, verfahren zu ihrer herstellung und diese enthaltende antimykotische mittel

Also Published As

Publication number Publication date
ES530113A0 (es) 1985-04-16
AU562292B2 (en) 1987-06-04
ES8504152A1 (es) 1985-04-16
ATE22685T1 (de) 1986-10-15
GR79547B (ko) 1984-10-30
DE3307217A1 (de) 1984-09-06
AU2506284A (en) 1984-09-06
HU191920B (en) 1987-04-28
IL71099A (en) 1987-10-20
IL71099A0 (en) 1984-05-31
DK83784D0 (da) 1984-02-21
DE3460893D1 (en) 1986-11-13
US4894382A (en) 1990-01-16
JPH0436153B2 (ko) 1992-06-15
JPS59164782A (ja) 1984-09-17
EP0118070A1 (de) 1984-09-12
EP0118070B1 (de) 1986-10-08
DK83784A (da) 1984-09-03
CA1226579A (en) 1987-09-08
ZA841551B (en) 1984-10-31

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