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KR830002745A - Preparation of Piperazine Derivatives - Google Patents

Preparation of Piperazine Derivatives Download PDF

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Publication number
KR830002745A
KR830002745A KR1019800001824A KR800001824A KR830002745A KR 830002745 A KR830002745 A KR 830002745A KR 1019800001824 A KR1019800001824 A KR 1019800001824A KR 800001824 A KR800001824 A KR 800001824A KR 830002745 A KR830002745 A KR 830002745A
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South Korea
Prior art keywords
compound
scope
alkyl group
compound according
carbon atoms
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KR1019800001824A
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Korean (ko)
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KR840001077B1 (en
Inventor
신고 마쓰무라
히로시 에노모도
요시아끼 아오야기
하루오 다나까
Original Assignee
모리시다 히로무
닛뽄 신야꾸 가부시기가이샤
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Priority to KR1019800001824A priority Critical patent/KR840001077B1/en
Publication of KR830002745A publication Critical patent/KR830002745A/en
Application granted granted Critical
Publication of KR840001077B1 publication Critical patent/KR840001077B1/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

피페라진 유도체의 제법Preparation of Piperazine Derivatives

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (51)

다음의 일반식〔I〕로서 표시되는 N4-카르바모일피페라지노 프로판올유도체 및 그 산부가염류.N 4 -carbamoylpiperazino propanol derivatives represented by the following general formula [I] and acid addition salts thereof. 단, 식중 R은 <EMI ID="2" HE="25" WI="110" FILE="kpo00002.TWhere R is <EMI ID = "2" HE = "25" WI = "110" FILE = "kpo00002.T 또는를 표시함. or Is displayed. 여기에 n은 1 또는 2를 표시하며, X는 할로겐을 표시하고, R1은 탄소수 6이하의, 불포화결합을 가지고 있어도 좋은 알킬기, 불포화결합을 가져서도 좋은 시클로 알킬기, 또는 아실기를 표시하며, R2는 H 또는 메틸기를 표시함. Z는 -CH2CH2NHCO2R3, -NHSO2R3또는를 표시함. 여기에 R3는 탄소수 4이하의 저급알킬기를, R4,R5는 동일 또는 달라져서 H 또는 탄소수 4이하의 저급알킬기를 표시함로서 나타낸 것을 특징으로 하는 피페라진 유도체의 제법.N represents 1 or 2, X represents halogen, R 1 represents an alkyl group having 6 or less carbon atoms, an alkyl group which may have an unsaturated bond, a cycloalkyl group which may have an unsaturated bond, or an acyl group, and R represents 2 represents H or a methyl group. Z is -CH 2 CH 2 NHCO 2 R 3 , -NHSO 2 R 3 or Is displayed. Wherein R 3 represents a lower alkyl group having 4 or less carbon atoms, and R 4 and R 5 are the same or different and represent H or a lower alkyl group having 4 or less carbon atoms. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. 인 특허청구의 범위 제2항기재의 화합물. The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제2항기재의 화합물.R is The compound of Claim 2 of the claim. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제26항기재의 화합물.R is The compound of claim 26 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제29항기재의 화합물.R is The compound of claim 29 in the scope of claims. R이인 특허청구의 범위 제29항기재의 화합물.R is The compound of claim 29 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제32항기재의 화합물.R is The compound of claim 32 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제34항기재의 화합물.R is The compound of claim 34 in the scope of claims. R이인 특허청구의 범위 제34항기재의 화합물.R is The compound of claim 34 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제 37항기재의 화합물.R is The compound of claim 37 in the scope of claims. R이인 특허청구의 범위 제37항기재의 화합물.R is The compound of claim 37 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제40항기재의 화합물.R is The compound of claim 40 in the scope of claims. R이인 특허청구의 범위 제40항기재의 화합물.R is The compound of claim 40 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. R이인 특허청구의 범위 제1항기재의 화합물.R is The compound according to claim 1 in the scope of claims. ※ 참고사항 : 최초출 원내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the original application.
KR1019800001824A 1980-05-08 1980-05-08 Process for n4-carbamoylpiperazino propanal derivatives KR840001077B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019800001824A KR840001077B1 (en) 1980-05-08 1980-05-08 Process for n4-carbamoylpiperazino propanal derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019800001824A KR840001077B1 (en) 1980-05-08 1980-05-08 Process for n4-carbamoylpiperazino propanal derivatives

Publications (2)

Publication Number Publication Date
KR830002745A true KR830002745A (en) 1983-05-30
KR840001077B1 KR840001077B1 (en) 1984-07-31

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Application Number Title Priority Date Filing Date
KR1019800001824A KR840001077B1 (en) 1980-05-08 1980-05-08 Process for n4-carbamoylpiperazino propanal derivatives

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KR (1) KR840001077B1 (en)

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KR840001077B1 (en) 1984-07-31

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