KR790001330B1 - Intrauterine dispesning catheter - Google Patents

Abstract

A appliance inserting materials into the Fallopian tube of female genitals was manufd. The appliance was composed of housing in which set materials container and perforating needle to flow materials. The materials such as tissue adhesives were inserted into the oviduct to occlude within short time by expansion of the balloon binded at the end of probe, and the inserted adhesives changed into tissue membrane eternally.

Description

Intrauterine medication

1 is a longitudinal section of a woman's genitalia and a dosage device inserted into the uterine cavity thereof,

2 is a plan view of the upper portion of the injection device,

3 is an enlarged sectional view taken along line 3-3 of FIG. 1,

4 is an enlarged sectional view taken along line 4-4 of FIG. 3,

5 is an enlarged cross-sectional view taken along line 5-5 of FIG. 4,

6 is a cross-sectional view similar to the fourth view showing the action of the injection device,

7 is a longitudinal sectional view of a slightly modified injection device section,

8 is an enlarged sectional view taken along line 8-8 of FIG.

9 is a similarity to that of FIG. 7 showing the operation of the injection unit,

10 is a cross-sectional view of an improved injection device section,

11 is a view similar to that of FIG. 10 showing the operation of the injection device,

12 is a longitudinal sectional view of another injection device part,

13 is a view similar to FIG. 12 showing the operation of the injection device,

14 is a side view of the needle and the container separated to receive the object from the container,

15 is a plan view on a sealed membrane of the container of FIG. 14,

16 is a longitudinal sectional view along line 16-16 of FIG. 15,

17 is a longitudinal sectional view of the sealed portion of the container,

18 is a cross sectional view along line 18-18 of FIG. 14,

19 is a similarity of FIG. 16 showing a state in which the container and the needle are coupled,

The top view of the improved dosing device,

21 is a longitudinal sectional view along line 21 of FIG. 20,

FIG. 22 is a longitudinal section along line 22-22 of FIG. 21;

FIG. 23 is an enlarged longitudinal sectional view along line 23-23 of FIG. 20;

24 is a similarity of FIG. 23 showing that the brake is released,

25 is a similarity of FIG. 23 showing an improved braking device,

26 is a plan view of yet another modification of the dosage device according to the invention,

27 is a longitudinal section enlarged view taken along line 27-27 of FIG. 26;

28 is a longitudinal sectional view along line 28-28 of FIG. 27,

29 is a longitudinal sectional view along line 29-29 of FIG. 27,

30 is a similarity to that of FIG. 29 showing a state where the movable part is in the second position,

31 is an enlarged cross sectional enlarged view of a fluid container used in the apparatus;

32 is a longitudinal sectional view of an instrument inserted for injecting drugs into a woman's genitals and fallopian tubes,

33 is a longitudinal sectional view of the injection device portion of the instrument according to the present invention;

34 is a plan view along line 34-34 of FIG. 33,

35 is a longitudinal sectional view of a female genitalia and medication device showing a slightly inflated balloon device and a drug in the uterine cavity;

36 degrees a similarity of FIG. 35 showing a state where the balloon is fully inflated,

37 is a similarity of FIG. 35 showing an improved dosage device,

38 is a similarity of FIG. 37 showing the injection site of the application instrument,

39 is a cross-sectional view of a female genitalia and a dosing device inserted therein illustrating how to inject a drug into both fallopian tubes,

40 is a genital sectional view of FIG. 39 showing a sleeve in a slightly inflated state,

FIG. 41 is a similarity of FIG. 40 showing that the sleeve expands to inject the drug into both Filippo canals;

42 is a cross-sectional view of the top of the application device in a position where the injection device section is not acting,

43 is a view similar to that of FIG. 42, showing the injection device being braked after the sleeve is fully inflated,

44 is a view showing that the injector unit is in a state of slightly inflating the sleeve and injecting drugs,

FIG. 45 is a similarity to that of FIG. 42 in which the injector portion is in a fully inflated sleeve,

FIG. 46 is an enlarged cross sectional view along line 46-46 of FIG. 39,

47 is a side view and a part of the longitudinal section of the actor;

48 is a longitudinal sectional view of an actor,

49 is an enlarged cross sectional view along line 49-49 of FIG. 47,

50 degrees is an enlarged longitudinal sectional view along the line 50-50 of FIG. 45,

51 is a longitudinal sectional view of the genitals and dosing device implementing a method of injecting drugs into both fallopian tubes,

52 is a sectional view of the uterus of FIG. 51 showing a balloon in an inflated state,

53 is a similarity of FIG. 52 showing that the balloon is fully inflated so that the drug is injected into the fallopian tubes,

54 is a longitudinal cross-sectional view of a woman's genitals and implanted device,

55 is a longitudinal sectional view of the upper portion of the application device of FIG. 54,

56 is a longitudinal sectional view along line 56-56 of FIG. 55,

57 is a longitudinal sectional view of the fluid container;

58 is a longitudinal sectional view along line 58-58 of FIG. 56,

FIG. 59 is a similarity of FIG. 58 showing that the movable portion is in the second position, FIG.

60 is a similarity of FIG. 58 showing that the movable portion is in the third position,

61 is a view showing that the liquid is pushed out of the container, as in the 55,56 degree,

62 is a similarity of FIG. 61 showing a state where the container is slightly smaller,

63 is a similarity of FIG. 61 showing a state where the volume of the container is completely reduced,

64 is an explanatory diagram showing that the medication device is connected to the uterine tube to operate;

65 is a partial cross-sectional view of the application instrument,

66 is an enlarged longitudinal sectional view taken along line 66-66 of FIG. 64;

FIG. 67 is an enlarged longitudinal sectional view along line 67-67 of FIG. 66,

68 is a longitudinal sectional view of the dosing device tip and the uterine canal;

69 is a longitudinal sectional view of the tip of the application instrument,

70 degrees is a cross sectional view along line 70-70 of FIG. 69,

71 is a longitudinal sectional view of the middle portion of the application instrument;

72 is an improved cava side view of the application instrument,

73 is an enlarged cross sectional view along line 73-73 of FIG. 72,

FIG. 74 is a cross sectional view along line 74-74 of FIG. 66,

75 is a cross-sectional view taken along line 75-75 of FIG. 66,

76 is a view similar to the one shown in FIG. 66 indicating the position where the brake device is locked;

FIG. 77 is a similarity to FIG. 73 with different shapes of wrinkles.

The present invention is limited to a device for injecting a certain amount of drugs into the conduit of the fallopian tubes of the female genitalia.

The appliance has a housing, a room within the housing, in which a container for storing the material is placed. A device having a passageway from the container is connected to the housing. Devices such as needles are able to drill holes in parts of the container, and objects in the container enter the passage through the needle and enter the device that receives the object.

The activator causes the vessel and the device that punctures the container to interact and allows the object to enter the device that receives the object through the passage from the container.

Conventionally, some of the containers are wrinkled on the side to store a certain amount of fluid. One side of the needle forms a portion of the container and engages with the container to form a device. The lower part of the container is tubular and it is sealed with a membrane. When the container is pushed, the needle penetrates the membrane and the object in the container goes out.

In one of the mechanisms, there are two tubes, two transit façades and an inner tube, with the second tube inside the first tube. At the tip of the first tube, there is an expandable sleeve, and when a fluid such as water or air enters the inside of the first tube, a constant pressure is applied to the inner wall of the uterine cavity. When the activator moves, the object is first injected into the first tube to inflate a certain amount of the sleeve, and then the drug, tissue adhesive, etc. are injected into the second tube to enter the uterine cavity.

Specifically, the present invention relates to a device for introducing a predicted amount of tissue adhesive from a woman's uterine cavity into the fallopian tube.

The device has a long message and an inflatable balloon at the end. The housing containing the activator serves to inflate the balloon and to inject the drug into the uterine cavity. Initially, the balloon is slightly inflated to form a certain shape to seal the lower part of the uterine cavity, and when moved a little more, the drug is injected into the upper part of the slightly inflated balloon. The inflated balloon pushes the drug into both conduits of the fallopian tubes, where almost all of the drug is injected into the catheter in a short time. Injecting a tissue adhesive into a conduit causes a reaction to form a polymer with the tissue of the conduit and closes the conduit. The adhesive eventually turns into wound tissue that permanently closes the conduit. The balloon can be easily removed from the uterine cavity by decomposing the activator in the housing to reduce volume.

The administered object may be mixed in advance or may be mixed in the uterine cavity after each addition.

The present invention includes a method of closing the catheter of a fallopian tube by inserting a device with an inflatable sleeve into the uterine cavity through the cervix. Pressing as an fluid on the expandable sleeve is in close contact with the inner wall of the uterine cavity at a uniform pressure. A fluid, such as a drug or tissue adhesive, is introduced into the upper part of the uterine cavity using a device. Fluid flows over the inflated sleeve and injects into the fallopian conduit. Tissue adhesives react with moisture in the fallopian tube tissue to exert adhesion to seal the conduit.

Other liquids may be injected that disrupt the tissue of the catheter.

Fibrous tissue is replaced by wound tissue that seals the conduit.

The instrument draws fluid out of the sleeve and then out of the uterine cavity.

One of the mechanisms by this invention has a shrinkable container in a cylinder. The needle device extends toward the container and is connected to each other by moving the container to drill a hole in the container. The activator pushes the containers towards the needle to connect one another and weave the containers to allow objects to flow out of the container. The container may be metallic, such as lead or alloy, capable of preserving emulsions such as tissue adhesives and of reducing volume.

The other is that the housing, the needle and the cover are coupled by a cover with the sleeve of the inflation line and a coupling device through which the needle passed in the way can be disassembled and assembled.

The cover is relatively inexpensive and can be disposed of in single use. The role of the cover is to prevent the liquid used to enlarge the sleeve from leaking into the uterine cavity.

By moving the plunger attached to the housing, the container is pushed toward the needle so that the needle and the container combine with each other to form a device. The drug enters the uterine cavity with a needle. With the inflated sleeve, the drug is introduced only into the upper part of the uterine cavity, from which the drug is injected into the fallopian conduit.

Because the inflated sleeve fills the uterine cavity and the pressure on the lateral and upper walls of the uterine cavity is relatively low and uniform, almost all of the drug is injected into the fallopian tubes, leaving only a very small amount in the uterine cavity. The instrument removes the fluid in the sleeve and pulls it out of the uterine cavity.

One type of instrument in accordance with the present invention is to inject the expected minimum amount of tissue adhesive into two conduits. The device has a long pipe-shaped device with an inflatable balloon at the end. The injection unit connected to the device initially inflates the balloon to fill almost all of the uterine cavity.

The sleeve is soft and inflated by the expected pressure to fill almost all of the uterine cavity. The pressure inside the sleeve is not constant when the walls of the uterine cavity are weak, ruptured or diseased, and when the sleeve is abnormal.

Regardless of the size of the uterine cavity, when the sleeve is inflated, it can check for abnormalities in the uterine cavity. Moving an actuator on the injector section pressurizes the fluid into the sleeve.

Once the predetermined pressure point is reached, the actuator is locked so that the pressure of the fluid no longer rises.

Once the pressurization stops, the fluid pressure in the sleeve maintains a low pressure even though the pressure drops slightly and continues to seal the lower part of the uterine cavity.

The instrument has a plunger to inject the drug in the container into the upper uterine cavity above the slightly inflated sleeve. The activator further expands the sleeve to fill the uterine cavity. The sleeve injects the evil inside the uterine cavity into a separate duct of the uterine cavity by this expansion. At this time, almost all of the drug injected into the uterine cavity is injected into the catheter.

It is an object of the present invention to provide a mechanism for injecting a predicted minimal constant object from the uterine cavity into two fallopian tubes. Another object is to provide a mechanism with movable activators that can first insert a tissue adhesive into the uterine cavity and inject the adhesive back from the uterine cavity into the fallopian tube before the adhesive solidifies in the uterine cavity. Still another object is to provide a mechanism for injecting an object into a fallopian tube using a low pressure in a single motion or continuous motion in a short time. Still another object is to provide a device which can be used regardless of the size and shape of the uterus and injects material into the fallopian tube with minimal pressure on the wall of the uterus. Another object is to provide a mechanism for injecting an object into a fallopian tube that cannot detect its position without exerting too much pressure into another body tube or blood stream.

Another object is to provide a balloon with a balloon that maintains a maximum pressure in a range that prevents unnecessary expansion of the uterine cavity. Yet another object is to provide a mechanism for injecting an object into a fallopian tube in a timely manner without delay in use due to its ease of use. Yet another object is to provide a mechanism for injecting different objects into the uterine cavity, respectively, and injecting the mixture into the fallopian tubes. Another object is to provide an apparatus for injecting a drug for treating infertility into the uterine cavity and fallopian tubes.

The invention is explained in more detail below in connection with the accompanying drawings.

In FIG. 1, 20 is a longitudinal section of the female genitalia, and 21 inside the uterine cavity is a catheter that induces injection of fluid such as drug tissue fixation into the fallopian tube. Tissue adhesives include monomers of isobutyl 2-cyano acrylate, mercury nitrate, or quinacrine. Cyanoacrylate monomers are liquid plastics that solidify when reacting with moisture or form polymers to close the fallopian tubes. Some drugs have a type that temporarily seals or closes the fallopian tubes, and over time the fallopian tubes can reopen and restore their function.

The genitals have a long vaginal cavity, labeled 22, which is wrapped in a cylindrical vaginal wall, labeled 23. Vaginal cavity 22 has a vestibule at 24, and the opposite side is connected to uterus 26. Uterus 26 is an abdominal organ with a thick wall and pupil, located between the bladder and the rectum. Uterus 26 has a triangular uterine cavity 27. Basal 28 of uterus 26 is attached to uterine body 29. Cervical 31 in the lower part of the uterus is the threshold between the vagina and the uterus. The uterine wall consists of serous layer on the upper part, thick and hard sphincter muscle on the middle layer, and internal mucosa fibers 32.

There are two fallopian tubes 33 and 34 in the upper part of the uterus, which are trumpet-shaped tissues connecting the ovary with the uppermost side of the uterine cavity. Ovaries are rigid, do not have a uniform shape, and are located at the top or bottom of the fallopian tubes on both sides of the uterus.

Fallopian tubes 33 and 34 have internal conduits 36 and 37 and have a fascia tissue about 12 cm long. Generally they are divided into isthmus intramural and ampullary. Conduits 36 and 37 act as pathways to transfer eggs from the ovary to the uterus. The catheter penetrates almost straight through the wall of the uterus and extends like the neck of a flask in the uterine cavity. The conduit has the best middle point. The conduit of the fallopian tubes consists of three layers of serous, muscular and mucosal fibers. The muscle layer is made of long muscle fibers, and when contracted, the tip of the fallopian tube comes into close contact with the ovary surface. Muscle tissue contains a lot of blood vessels form a bundle of muscle fibers and swelling, so push the fallopian tube to the surface of the ovary.

However, such a series of operations are stopped when an abnormality occurs in the pipe, but when the conduit is blocked by the present invention, this operation is not impeded.

The catheter 21 has a long forearm 38 that can be inserted through the vaginal cavity and into the uterine cavity 27, and at the end is a sleeve 40, which is inflatable, such as a balloon, by a band 40. The outer end of the sleeve is connected at the outer end of the tube. The sleeve has a rubbery shrinking expandability, and the rubber has a uniform surface tension and a uniform expansion force. When inflated, the sleeve adheres to the inner wall with uniform pressure regardless of the size of the uterine cavity. Therefore, it can be used by many people as the same catheter. When the sleeve expands under the pressure of a fluid such as water or air, it becomes boat-shaped. The end of the tube is plugged by a plug 43 and there are many holes 42 on the side connecting the tube and the inside of the sleeve to each other.

The top of the tube 38, which is inserted through the pruning 24, is coupled to the inlet 44 of the fluid, which may be detachably coupled. The inlet is contained in a housing with a movable plunger 47.

Moving the plunger 47 in the direction of the arrow 48 pushes fluid such as water out of the inlet 44 into the inflatable sleeve 39 to seal fill the uterine cavity 27.

Tube 38 contains small tubes 49 and 52, which inject fluid into the uterine cavity 27. Tube 49 extends out of tube 38 and engages another inlet 51. In this way the tube 52 is connected to the inlet 53. The injection units 51 and 53 have the same structure, so that a certain amount of homogeneous drugs or different drugs can be injected at a time difference, and one can add a liquid neutralizer. The following description relates to the injection section 51.

In FIGS. 2-5, the inlet 51 has a housing 57 of cylindrical sidewalls 58 and bottom 59. The housing 57 has a tub 61 and an outwardly extending ear projection 62 and 63. These projections extend outwardly from the cylindrical side wall 58, respectively. The corrugated container, labeled 64, is in the container 61, which can store drugs or therapeutic drugs that close the fallopian tubes. The vessel 64 consists of an accordion-shaped cylindrical side 66 and a flat bottom 67 with a tube 68 vertically embedded in the center of the base 67. Tube 68 is provided with an outwardly extending portion 68A and an inwardly extending portion 68B.

Tube 68 is transversely blocked by membrane 69 and is located at the bottom 67 of the vessel. The other side of container 64 is sealed with a seal.

Containers should be made of lead alloy that can reduce internal volume and block moisture and vapor. Similar materials may be used to form part of the container.

Materials of this nature prevent moisture and vapor sensitive drugs from solidifying or polymerizing during storage. The material of the container is chemically inert to the stored object.

Within vessel 64 there is a longitudinally extending needle 73, with a hollow, inclined tip 74 in the shape of a pipe, reaching the vicinity of membrane 69. The upper part of the needle 73 is connected to the round disc 76.

As shown in FIGS. 4 and 5, there is an elongated passage 77 inside the needle. There is a hole 78 on the side of the needle to allow objects in the container to enter. Multiple holes may be provided in the needle 73.

The keg 61 is supported by a movable plunger 79. The outer periphery of the lower end has protrusions like 81 and 82, which are engaged with the grooves 83 and 84 on the inner side of the housing. This turn allows the injection device to move in a constant direction along the barrel. The lower part of the plunger has a groove inside to allow the contracted race to enter. There is also a groove 87 in the center of the groove 86 to enter the sealed top 71 of the container. The plunger 79 can be removed from the housing, thus replacing the container.

In FIG. 6, the inlet 51 is operated by pushing the plunger 79 into the pail 61. This operation is completed by pushing the plunger completely into the housing in the direction of the arrow 88. Place index finger and middle finger under protrusions 62 and 63 and apply force to plunger 75 with thumb. The needle 73 passes through the membrane 69 and the fluid in the vessel 64 is pressurized and pushed through the passage 77 through the passage 77 into the bub 49. Fluid eventually exits the shortest portion 54 and enters the fallopian conduits 36 and 37 along the inner wall of the uterine cavity base. The plunger 79 is pressurized until all the objects in the vessel 64 are pushed out. Sleeve 39 maintains a constant shape with the inner wall of the uterus, so the amount of objects left there is constant.

The injection section 51 is a one-time use type that contains a fixed amount or a one-time use amount of a fluid such as a drug. This infusion can be used as part of a syringe for injecting the drug into the body. Tube 49 may be replaced as a tubular needle, which is located on tube 68 extending outward. The tube 68 is screwed to fix or detach the needle. Tube 68 can be bound to long news, decomposed or permanently bonded.

7,8 and 9, a variant of the injection section is shown at 100, which when actuated pushes a fluid, such as a drug, into a tube or needle.

Tube 101 becomes the delivery device of Catheter 21. The housing 102 has a cylindrical side wall 103 and a flat bottom 104. Projections 107 and 108 are formed at both ends of the side wall 103. Inside the can 106 is a container 109 for storing fluids such as drugs, tissue adhesives, water, air, gases, semi-fluids, and the like. The container 109 consists of a cylindrical side 111 and a flat base 112 and has a volume-reducing structure. The center of the base 112 is equipped with an elongated tube 113. This tube has a portion 113A extending outwardly through the hole 114 and a portion 113B extending inwardly. The membrane 116 is provided laterally in the center part of the tube 113, and the tube 113 is sealed. The upper end of the container is folded and sealed 117. The long needle 118 is located in the container 109 and the pointed tip 119 of the needle lies inside the tube 113. The discoid top 121 of the needle is attached to the upper inner wall of the container 109. As shown in FIG. 8, when the middle side of the needle is open and the needle drills the membrane 116, it flows along the needle tip 119.

As shown in the needle 73 of FIG. 6, there are many holes formed in the side of the needle to facilitate the flow.

At the top of the housing 102 is a plunger 122. The plunger 122 has two protrusions 123 and 124, which are fitted in the two grooves 126 and 127 of the inner wall of the housing so that the plunger 122 can move in a vertical direction. The lower center of the plunger has a groove 128 to allow a portion of the container to enter. In the center of the groove, the pupil 129 enters the sealing portion 117 of the container.

Referring to FIG. 9, when the mechanism is actually used, the plunger 122 is pushed in the direction of the arrow 121 to enter the cylinder 106. The plunger is then pressed flat and the needle passes through the membrane 116.

As the tip 119 of the needle passes through the membrane 116, the fluid in the container 109 can immediately enter the tube 101 through the needle. The plunger can then enter until the end reaches tube 113 and the fluid will flow out until this time.

10 and 11 show modifications of the needle and vessel arrangement. A portion of the bottom of the container 132 has a flat base 133. Tube 134 is located in the center of this base. This tube has an outwardly extending portion 134A and an inwardly extending portion 134B. And within this tube is a membrane 136 on the same line as the base 133. On the same line as the tube 134, there is a needle 137, the end of which is conical 139, connected to the long leg 139. Referring to FIG. 11, moving the needle 137 in the direction of the arrow 141 causes the needle tip 137 to drill a hole in the membrane 136, which is larger than the leg 139 so that the fluid in the container passes through the membrane and enters the tube 134. The outer part of 134A of tube 134 is screw 142 and can be connected to other parts.

A fluid container 143 is shown in FIGS. 12 and 13. The side 144 of the vessel is not flattened and is connected to the circular base 146. The central part of the base 146 has a tube 147, and the part which extends outward is 147A, and the part which extends inward is 147B. Inside the center of the tube is a membrane 148 that seals the tube in line with the base 146.

The long needle 149 is in the container and the tip 151 extends toward the inner 147 portion of the tube and the head is disc 152. The disc 152 fits into the side 144 of the cylindrical container and prevents moisture from entering the interior of the container. Needle 118 may be U-shaped or tubular as shown in FIG. 8. The shape of the needle may be as shown in FIGS. 10, 11.

As shown in FIG. 13, when the upper portion 152 is pressed in the direction of the arrow 154, the end 151 drills a hole in the membrane 148 and the fluid in the container is discharged along the needle.

In Figures 14-19 a container labeled 160 is shown. The vessel 160 and the needle 161 are collinear and the head of the needle is disc shaped and the housing is coupled.

The side wall 164 of the vessel 160 is accordion shaped and the front portion 167 has a sleeve 168 containing a membrane. The end 171 of the sleeve is packed to hold a pad of sponge.

The rear part 172 of the container is sealed. As shown in FIG. 17, these seals 173 overlap. The material of the container blocks moisture and steam, and the lead alloy is chemically inert to the stored objects. It is an essential condition of the container material to block moisture or vapor so that objects in the container do not harden or polymerize during storage. Cyanoacrylate is a typical example of monomers that are sensitive to moisture and steam, which will harden soon after exposure to moisture (such as moisture in tissues) and should be stored in a container that is protected from moisture or steam.

In use, the tip wall 172 is pushed in the direction of the arrow 174. When pushed in this way, the container 160 moves and is connected to the needle 161. The side 164 of the container is distorted, and the object flows out.

In FIG. 20, a catheterized dosing device is shown, which has an inlet 200 and a long catheter 202 with a balloon. The housing marked 201 is connected with a long tube 203 of a catheter type. Tube 203 may be an extension of the housing or may be detachably coupled.

At the end of the caser is an inflatable sleeve 204 which is inflated by a fluid such as water or air. As shown in FIG. 22, a small tube 206 is penetrated inside the tube 203 and there is an ejection opening labeled 205. The end of the tube 203 can be grooved so that the object can exit the outlet 205 without interruption.

As shown in FIG. 22, two long barrels 207,208 are made side by side in the housing 201. Tube 207 and tube 203 are connected by passage 209 and passage 211 connects cylinder 208 and tube 206. A short cylindrical needle 212 rises inwardly of the canister 207 and the discoid base 213 of the needle is located in the passage 209. The base 213 of the needle is joined in the keg 207 and the needle is collinear with the passage 209.

Another needle 214 is located to the longitudinal side of the keg 208 and the bottom 216 of the needle is below the keg 208 and is connected to the passage 211.

Container 217 is contained in barrel 207. The barrel has a membrane 219 facing the needle 212 and a pad 221 is attached to the container side between the needle and the membrane. There is a plunger 222 on the back of the vessel, which can be connected using a suitable object 237. The elongated rod 223 and the plunger 222 are connected and extend in the holes 224 in the housing. A coil spring 226 is wound around the rod to press the plunger into the container.

The lock mechanism 227 is locked to the rod 222 so that the needle and the membrane are in a locked position. Referring to FIGS. 23 and 24, the lock mechanism 227 is cylindrical 228 and extends downward through the groove 230 of the rod 223. One end of the cylinder 228 has a semicircular cutting portion 231 in line with the rod 223.

At the top of the cylindrical 228 is a handle 232.

As shown in FIG. 20, the handle 232 may move in the direction of arrow 233 to insert a rod into the semicircular cutting groove 231. Once the grooves 231 and rods 223 are pressurized (same as 18th degree), the rods can move forward. The spring 226 pushes the plunger 222 towards the needle 212, causing the container 217 and the membrane 219 to be pushed toward the needle. At this point, the tip of the pointed needle 212 passes through the pad 221 and makes a hole in the membrane. The fluid in the vessel then enters passage 203 through the needle. At this time, the fluid in the container is almost entirely through the needle by the force of the spring.

As shown in FIG. 21, the plunger 222 is connected with an upwardly extending protrusion 234. This projection 234 extends between the grooves 236 longitudinally dug into the housing. The upper portion of the projection 234 is enlarged so that it can be gripped. As shown in FIG. 22, the plunger 222 and the container 217 are connected by the connecting device 237, and when the protrusion 234 is pulled in the opposite direction, the container 217 is expanded again to recover the fluid inside the catheter and expand the expandable sleeve 204. Volume is reduced. The plunger 222 can be pulled to a position where it can engage with the lock mechanism 227 in the housing. Other than the device for recovering the fluid from the sleeve 204 may be used.

There is a container 238 in the barrel 208 connected to the needle 214.

Inside the vessel 238 is a room 239, which contains fluid and at the end of the vessel there is a membrane 241 away from the tip of the needle 214. In front of the membrane, a pad 242 is provided. Moisture and vapor sensitive drugs should be placed in containers of moisture and vapor resistant material and lead alloys are preferred. The nature of these materials is essential to prevent moisture and vapor sensitive objects from hardening or polymerizing during storage. The material of the container should be inert to the stored object. At the top of the vessel there is a plunger 243 and a rod 244 connected to the plunger 243 is inserted long into the hole 246 in the housing. A spring 247 in the pail in the housing can push the plunger 243 towards the needle and the rod 244 is locked to the lock mechanism 248. Lock 228 is identical to lock 227. These are operated by turning the knob in the dotted line direction, as shown in FIG. This releases rod 214 and spring 247 pushes the plunger forward, pushing the membrane into the needle bar.

The pointed end of the needle drills a hole in the membrane 241 to connect the vessel and the passageway 211 to allow fluid to enter the tube 206. The hole between the membrane and the needle is well sealed so that only through the needle the object enters the tube 206 along the passageway 211 when the spring force is applied.

The housing 201 is openable and replaceable for the containers 217 and 238 in the bins 207 and 208. Other containers mentioned herein may also be encased.

In FIG. 25, 250 is shown in a variation of the lock mechanism. The instrument has a rod 251 which has a semicircular cut groove 252. The rod 223 connected to the plunger has a similar groove. A spring 253 located inside the hole 224 holds the lock mechanism 251 upwards. At the top of the lock is a round head 254.

When using this, push the head 254 in the direction of the arrow 256 so that the groove 252 fits into the rod 223. At this time, the spring 226 pushes the rod 223 to connect the membrane 219 with the needle 212.

In Figures 26-29, variations of the catheter are indicated at 300. This catheterized dosing device includes an injection section 301 and an elongated tubular catheter section 302. The housing 303 in the inlet is connected to the long tube 304 of the catheter.

Tube 304 may be coupled to the housing in a possible combination or may be connected as part of the housing. At the end of the tube 304 an inflatable sleeve 305 hangs by a band 306. Sleeve 305 is elastic, such as flexible rubber or plastic, and applies uniform pressure to the uterine cavity wall when it is expanded in the uterine cavity. The sleeve serves to restrict the drug introduced into the uterine cavity by expansion and to prevent it from flowing out of the uterine cavity. The upper openings 307 of the tube 304 serve as a gateway for fluid such as water to flow out of the tube and enter the sleeve to expand the sleeve. Tube 308 in tube 304 has an outlet 309 through tube 304.

In the housing 303, two barrels 311,312 are made horizontally long side by side. The bins may be placed side by side vertically. 311 is connected to tube 304 by passage 313, and passage 314 connects tube 312 and tube 308.

The first flanger 316 is located in the barrel 311, and the rod 317 connected to the flanger extends backwards. The second plunger 318 has a barrel 312 in which a rod 319 connected to the flanger extends rearward alongside 317. The actor (or trigger), indicated at 320, is connected to the back of the rods 317,319.

Trigger device 320 has trigger 321 and the middle of the trigger has a hole through which pin 322 can enter, which is pinned to the bottom of the handle at the rear of the housing. The spring 325 connects the top of the trigger 321 with the housing and the top front 324 of the ring is connected to the rods 317,319.

29 and 30, the trigger head 324 has a long hole 326 connected to the top of a round hole 327 into which the rod 319 can enter. In this hole 327 there is a pin 328 which can be moved inside, the neck 329 of the pin is narrow and the head 331 is large. The spring 332 connects the head 331 of the pin and the plug 333 which seals the lower part of the hole. The pin is pushed by the spring to cool down passageway 326. Rod 317 has a protrusion 334 protruding backwards, and when the rod is in the locked position, the protrusion is located below the head 331 and prevents pin 328 from entering passage 326.

Referring to FIG. 27, the rod 317 has a hole 336 at the top, which serves to secure the debon 317, which is connected to the lock 337, to the “injection position”.

Lock 337 has a movable pin 338, which is pinched in a passageway enclosed by protrusion 339. The head 341 of the pin 338 protrudes out of the housing so that it can be held by hand, thereby unlocking the lock. The front of the pin has a C-shaped ring 342 that acts as a brake against the spring 342. The spring 343 is mounted around the pin and is connected to a part of the housing 303 to push the pin toward the rod 317. If the rod 317 is in the "injection position", the pin 338 is pushed into the hole 336 by a spring. The rod 319 also has a hole 344. The lock 346 on the housing 303 locks the pin in the "injection" position. Lock 346 And lock 337 is the same.

In FIG. 30, when the lever 323 is operated for one month, the rod 317 is fixed to the "injection" position by the lock 337. As the rod 319 enters the hole 326, the head 324 is relatively movable so that the rod 319 does not move. When the head 324 is returned to its original position by the spring 325, the pin 328 enters the hole 326 by the spring 332. Move lever 321 back toward handle 323 and rod 319 will move forward. In FIG. 28, the first container, labeled 350, is contained in the barrel 311, and the needle 351 coupled to the base 352 of the disc is in the barrel. Needle 351 is drilled to allow emulsion to pass through passage 313.

The vessel labeled 353 is contained in barrel 312, with a needle coupled to the disc-shaped base 356 extending longitudinally in the barrel. Needle 354 is a tube that causes fluid to flow into tube 314. Container 353 is a long cylinder of glass or plastic with a head 357. The head has a rubber cap and lies on the same line as the needle 354. Inside the vessel is a piston 358 which keeps the fluid in the vessel. The plunger 318 in the vessel is adapted to be connected to the piston 358. Moving the plunger forward causes the head 357 to be pierced by the needle 354 to allow fluid in the vessel 353 to flow into the tube 314. The fluid is pushed out of the vessel by the forward movement of the piston. Fluids are drugs, tissue adhesives, and semi-fluids, which can treat or close the fallopian conduits.

There is a cylinder 361 capable of storing a fluid such as a drug or water in the container shown at 350 in FIG. The front end of the cylinder has a head 363 sealed with a plug 364. The opening of the cylinder is closed by a plunger 366 with a piston 367. The back of the plunger has an ear 368 to allow the spring 369 to connect. The front end of the spring 369 is engaged with a ring on the cylinder 361, which pushes the plunger 366 towards the outside of the cylinder 361. Inside the plunger 366 there is a longitudinally extending hole 372 which causes the activator rod 373 to slide in. A spring 374 in a hole in the center axis of the rod connects the rod 373 with the plunger 366.

Plunger 316 connected to rod 317 is connected to the end of rod 373. As the plunger 316 moves forward, the spring 374 pressurizes the plunger 366 and moves the barrel 361 forward so that the needle 351 makes a hole in the march 364 so that the fluid in the container can be connected to the passage 313. As the plunger 316 continues to advance, the piston 367 also advances towards Marve 364, causing the fluid in the vessel 361 to enter the sleeve 305 through the tube 304 and the hole 307 and expand. The sleeve 305 expands with uniform pressure to fill the uterine cavity and apply uniform pressure to the uterine cavity wall. The pressure at this time is uniform regardless of the size of the uterine cavity. The housing 303 is provided with a door that can be opened and closed so that the containers 305 and 353 can be placed in the canisters 311 and 312 and can be replaced. Other containers described herein can also be used.

In use, the catheters do the role of injecting drugs, tissue adhesives, contraceptives, or similar objects into the fallopian tubes. This role includes the insertion of an elongated catheter 302 with a contracted sleeve 305 through the cervix into the endometrium. The sleeve 305 expands under pressure of the fluid to fill the uterine cavity and apply uniform pressure to the inner wall of the uterine cavity. The fluid is pressurized and introduced into the sleeve 305 from the tube 304. As the activator 320 advances and advances the plunger 316, the vessel is advanced to connect with the needle 351. The needle 351 drills the plug 364 so that the fluid enters the tube 304 and inflates the slab again. The sleeve is made of elastic rubber or similar material and has a low surface tension to apply uniform expansion pressure to the inner wall of the uterine cavity. Therefore, using the same type of catheter furnace, the uterine cavity can be tightly sealed regardless of the size of the uterine cavity.

The drug is pressurized, injected between the inflated sleeve and the uterine cavity, and then pushed by the inflating sleeve to be injected into the fallopian conduit. One of the drugs is a tissue adhesive, which can be injected into the conduit, which reacts with moisture in the conduit tissue to form a polymer to close the conduit. Drain the fluid in the sleeve to deflate the sleeve, and then pull the catheter out of the uterine cavity.

In FIG. 32, the dosing device 420 is shown with the news inserted into the uterine cavity. The female genitalia, labeled 421, has the uterus 422 and two fallopian tubes 423,424 connected to the uterus. The lower part of the uterus 422 is connected to the long vagina 426, vaginal cavity 427 and vestibular 428. The upper part of the vaginal cavity is connected to the cervix 429. The cervix 427 has an opening 431 and serves as a passageway connecting the vaginal cavity 427 and the uterine cavity 432. Fallopian tubes 423 and 424 have exits 433A and 434A above the 432 uterine cavity.

Uterus 422 is generally belly-shaped, thick-walled, hollow, and located between the rectum and bladder. The shape and size depends on the woman. Women's thickness, intensity, and sensitivity to pain also vary. The size and shape of the uterine cavity is also different. Uterine cavity 432 is generally triangular and flat. Some wombs have different shapes of the uterine cavity.

The fallopian tubes 423,424 are paired and extend from the top of the uterine cavity to the ovaries about 12 cm long. The location of the exits 433A, 434A of the two conduits 433, 434 is varied by the uterine cavity. The two outlets are usually in a position as shown in FIG. 32 of symmetry, the size of which depends on the shape and size of the uterine cavity and also on the woman. Fallopian tubes are generally divided into buccal, internal and ampoule sections. The two conduits not only serve as a pathway for carrying eggs from the ovary to the uterine cavity, but also serve as a pathway for carrying spermatozoa from the uterus to the ovaries. The fallopian tubes pass almost straight through the wall of the uterus, but can be adorned by some women. The wall of the fallopian tube is formed of three layers of a mucus layer, a muscle layer, and mucosa fibers.

Inside the uterus 422 is the uterine cavity 432, enclosed by an upper wall or base 436 and two side walls 437,438. The upper wall and the two side walls have a mucosa 439, which is to be peeled off periodically.

Dosing device 420 has a news 441 long enough to be inserted into the uterine cavity through the vaginal cavity, with a long passage 442 penetrating therein. A balloon marked 443 hangs at the end of the tubular 441. The balloon is inflatable and secured by something like screw 446. Similar fixture 447 may attach the bottom of the sleeve to the operator. The reader 441 has several holes 448 that serve to connect the interior of the sleeve to the passage 442.

The sleeve 444 is of a soft, expandable, elastic tubular form, such as rubber or plastic, and has a very low tension when inflated. As an example, latex rubber with low surface tension is a suitable material for the sleeve. Because of the low surface tension, the rubber expands evenly under low pressure. The sleeve easily expands to match the shape of the uterine cavity and does not apply pressure to the walls 437,438 of the uterine cavity. As shown in FIG. 36, the sleeve completely fills the uterine cavity and is uniformly in contact with the mucosal layer 439 of the uterine cavity. Known inflatable catheters are relatively rigid and rigid and do not match the shape of the uterine cavity when inflated.

The top of the reader is closed with the lid 451. Under the lid there is a hole 452, which is connected to the passage 454, which connects to the tube 453 inside the 441. The top 456 of the lid is intended to reach the base 436 of the uterus.

According to FIG. 33, the medication instrument 420 has an elongated housing 457 connected to the end of the news 441. The first chamber 458 in the housing contains one long cylinder 459. The tube 462 is connected to passage 442 in the operator 441 so that fluid such as air in the barrel 459 can enter the balloon along the passage 442. The other side of the keg 459 has a piston 463 to keep the fluid in the keg, and the piston has a hole to allow fluid to enter the keg.

At the rear of the piston 463 is the first actuator 467, which is able to push the piston 463 into the cylinder 459. The first actuating device is connected to an actuator 468 protruding rearward from the housing.

There is a second seal 469 in the housing 457 and can be connected to one part of the first seal 458. The tube 453 in the speaker 441 is connected to the second chamber 469 by a tube 471 in the housing 457. At the end of the tube 471 is a needle 472 extending long into the second chamber 469. The other side of tube 471 is connected to tube 453 and its end is connected to lid 451 at the end of 441. As shown in FIG. 32, the second chamber 469 is made elongated, in which the container 474 lies coaxial with the needle 472. At the front of the container is a plug 476 which can be drilled through. The rear of the vessel is open but closed by a piston.

The second actuating device 479 extends to the rear of the container 474 and is coupled to the operator 468 to operate. Actuator 468 is intended to inject the drug into the fallopian tubes in a single motion. At the rear of the housing 457 are two projections 481,482 which can be held with two fingers to activate the actor 468. Actuator 468 has a hole 483 for pin 483A to lock the actor in the operating position. Pin 483A prevents inadvertent operation of the actor.

Actuator 467 is a force transmitting device that expands sleeve 444 by pushing piston 463 into cylinder 459 to increase pressure in balloon device 443. The actuator labeled 467 has a cylinder (or sleeve) 484 and is capable of dragging the fuselage indicated by 486. The top of the sleeve 484 is connected to the head 487 and has a hole in the center of the head 487 to communicate with the inside of the sleeve 484. The lower end of the piston 463 has a conical portion 489 and engages with the top of the conical head. The hole 488 is coaxial with the screw inserted into the fuselage 486, which can be adjusted up and down using a tool such as a screwdriver. The springs 492 and 493 rise in opposite directions around the perforated washer, which springs against the head 487 and spring 493 against the fuselage 486. In this way, the first operating device 467 can be moved in the longitudinal direction. The screw 491 is designed to adjust the change in the microelasticity of the spring 493 to create the desired fluid pressure in the container.The spring 492 is relatively fragile and compresses even at a weak pressure of 2-3 psi. It is supposed to push part 487. Thus, the sleeve 444 can expand even with a constant minimum pressure. The minimum pressure to be used depends on the elasticity of the spring 493 and the spring 493 can be adjusted appropriately according to the shape of the uterus, allowing the instrument to adapt to the shape and size of the uterus.

The sleeve 484 and the fuselage 486 can move along the groove 498, which is embedded in the hole 497 drilled on the sleeve 484, along the groove 498 longitudinally dug into the housing so that the actuator 476 can move without the spring 492,493.

The fuselage 486 has a cylindrical passageway 499, which contains a connecting rod 501, with beads on both sides of the rod. The left first end of the connecting rod 501 enters the cut groove 502 next to the activator, and the second groove 503 is cut below it, and below it is projected to allow the activator and fuselage to be caught when the connecting rod is in the second groove. There is a site. The third groove 506 is inserted in the housing to allow the connecting rod 501 to enter. The third groove is in an operationally advanced position with respect to the first groove. When the connecting rod is in the third groove 506, the operator 468 is moving. In addition, the fuselage may stop for a while and the fuselage will continue to move when the 504 part of the actor catches the fuselage 486. The location of another groove 521 and groove 506 in the housing is arranged such that the sleeve can be inflated again after the drug is put on top of the slightly inflated sleeve 444 while the fuselage is stationary for a while. In this case, the expansion of the sleeve depends on the pressure of the fluid.

A lock 507 is installed inside the fuselage 486, which consists of a plunger 509, a protrusion 510 and a spring 512, which are supported outwards by a spring. The protrusion is inserted into a hole drilled in the sleeve 484 as the body moves forward and is caught by one of the teeth 511 formed in the housing. The opening 513 in the sleeve is arranged to limit the pressure of the fluid to a certain degree, and the shape of the teeth is such that the body can only move rearward by the protrusions.

The second actuator 479 pushes the vessel 474 towards the needle and pushes the piston 477 into the vessel to allow the drug to enter the tube 453 along the needle 472. Tube 453 causes fluid to enter the top of uterine cavity 432 through head 451. Referring to FIG. 33, the second actuator 479 has an elongated plunger 514, which can move along the elongated passage 515 in the housing 457, the top 516 of the plunger 514 can be connected to the piston 477, and the bottom of the plunger 514 There is a circular hole 517. The hole 517 contains a connecting rod 518, which is made of a tube and has beads at both ends. One end of the connecting rod 518 can be inserted into the semicircular cutting groove 519 on one side of the actuator 468. When the groove 519 and the connecting rod coincide, the actuator 468 and the plunger 514 can move simultaneously. When the connecting rod 518 is coincident with the groove 521, the operator Although 468 can continue to move, plunger 514 will stop.

In use, the dosing device 420 has a room 469, in which the container 474 is contained. Agent 468 is braked by pin 483A embedded in hole 483. Pin 483A is hooked to a portion of housing 457 so that actor 468 is movable. The instrument must be well sterilized before use.

Operation begins by inserting balloon device 443 into uterine cavity 432 through vaginal cavity 427 cervical 431, as shown in FIG. Sleeve 444 is retracted to facilitate insertion into the uterine cavity. Insert 441 until head 451 reaches uterine base 436. Because the shape, size and position of the uterus are not constant, the sleeve may or may not have a point of symmetry with respect to both fallopian tubes. In some cases, the sleeve may be biased to one side, but the instrument 420 is capable of injecting drugs into both fallopian conduits no matter how the balloon is positioned in the uterus 432.

Hold the projections 481,482 on both sides of the housing with two fingers, place your thumb on the actor, remove the pin from the hole 483, press it forward, and the plunger 468 enters into the housing, slightly inflates the sleeve and introduces the drug into the uterine cavity. Again the sleeve is fully inflated to inject the drug into the two fallopian conduits. This allows the sleeve 444 to be more inflated so that the drug injected into the uterine cavity enters the fallopian tube via the inlet 433A, 434A of the catheter. The sleeve is then inflated until the pressure of the fluid is 8 psi. This pressure is determined by springs 492,493 and screws 491. When the fuselage 486 reaches a certain position and the projection 510 is in line with the hole 513, the spring 512 in the back of the plunger 509 is pushed out of the hole 510 to be inserted between the teeth 511 and the operator 468 is fixed. The fluid pressure in the sleeve is then governed by springs 492 and 493.

The joint rod 518 is moved from the groove 519 to the groove 521 while the activator 468 is in the position of FIG. 36 from the position of FIG. 35 and the operation of the plunger 514 ends by injecting the drug into the uterine cavity. The activator 468 then advances further to inflate the sleeve to inflate it so that the drug is injected into the fallopian conduit and the sleeve does not expand further after the uterine canal is fully filled. At this time, the pressure can be injected into the fallopian tubes, but is not strong enough to be injected deeper and into other body cavities. In FIG. 35, the actor 468 only slightly enters the housing 457 and the first actuating device can be seen that the piston 463 is advanced toward the keg 459. In this case, the sleeve 444 expands slightly under the uterine cavity to seal the uterine cavity. The sleeve is in close contact with the lining of the uterine cavity. The connecting rod 501 combines the actor 468 and the first actuator 467 so that the force applied to the operator 468 can be transmitted to the first actuator 467. Piston 463 then advances into room 464. The articulation rod 518 combines the plunger 514 and the actuator 468 so that the piston 477 at the top of the plunger can advance toward the vessel 474, allowing the needle 472 to drill a hole in the plug 476 on the front of the vessel 474 and enter the interior of the vessel. do. When the connecting rod 501 is in line with the groove 506, the rod protrudes to the right to release the fuselage 486 from the operator 469.

Continuing advancing the actor 468, the plunger 514 advances the piston 477 to pass the drug labeled 478 along the needle 472 through the passage 471 through the tube 453 through the hole 452 which penetrates right and left just below the head 451 through the tube 453. By the time the drug 478 has been fully discharged, the connecting rod 518 is inserted into the groove 521 so that the plunger 514 is fixed to the housing. At this time, the joint 501 is engaged with the groove 503, and at the same time, the left rear end of the fuselage 486 is caught by the 504 part of the actor so that the fuselage can move forward again.

The player 468 is then retracted. The worker and fuselage 486 are retracted together because the joint 501 is in the groove 503. The protrusion 510 is able to move back along the tooth 511. As the player retreats, the piston 463 also retracts so that the fluid in the sleeve escapes, causing the sleeve 444 to contract and to be removed from the uterine cavity of the patient.

Conduits 433 and 434 are permanently closed by using drugs such as coarse adhesive of cyanoac salt formulations. Tissue adhesives of the cyanoacrylic salt line cause fibroblastic prolifereation to close the conduit 433,434 for an appropriate time. The adhesive causes a polymerization reaction when it comes into contact with an object with hydroxyl ions such as water. The cells in contact with the adhesive are destroyed and eventually replaced by fibrous tissue. Some adhesives are polymerized by body temperature or other stimuli.

In use, the medication device is intended to inject the drug into the fallopian tube. As shown in FIG. 32, a balloon device 443 in the initially contracted state is inserted into the uterine cavity through the vaginal cavity and cervix, and an operator 468 You can use it to complete the entire process of operation. That is, the first operating device 467 and the second operating device 479 are properly arranged so that the sleeve 444 first expands slightly to seal the lower part of the uterine cavity, and then the plunger 514 advances the piston so that the drug in the container expands slightly. Into the uterine cavity above the top of the sleeve (see FIG. 35), the sleeve is again fully expanded by the advancement of the piston 463. Actuator 468 may advance until lock 507 engages tooth 511, and once locked, sleeve 444 will not expand further. The maximum pressure applied to the sleeve is predetermined so that unnecessary pressure is not applied to the wall of the uterus. The sleeve pushes the drug introduced into the uterine cavity by expansion into the conduit 433,434 of the fallopian tube. Retractor 468 retracts the fluid back into the container to remove the pressure applied to the sleeve and deflate it, thereby withdrawing the instrument from the uterine cavity through the cervix and vaginal cavity.

Drugs are fluids or semi-fluids used for diagnosis, treatment or closure of fallopian tubes. An example is a tissue adhesive.

Tissue adhesives are those used as cyanoacrylic salts or surgical adhesives. Cyanoacrylic salts are liquid plastics that react with moisture to polymerize or adhere and act to close the fallopian tubes. Among the cyanoacrylic salts, of course, but not all are listed here, methyl cyanoacrylate, methyl-2-cyano acrylate, n-amyl cyano acrylate, n-hexyl cyano acrylate, n-butyl cyano Acrylate, n-amylcyano acrylate, n-hexane cyano acrylate, n-heptylcyano acrylate, isobutyl-2-cyanoacrylate, n-octylcyanoacrylate, and the like.

Some medications may cause sticking due to body temperature or other stimuli. Some of them may be a permanent closure of the palopioduct, or a temporary blockage or closure. In the latter case, the catheter may be reopened to restore normal function. Examples include contraceptives, water, silicone elastomers, formaldehyde preparations and the like.

37,38 a variant of the instrument of the present invention is shown at 420A. The markings of all corresponding parts and the like are the same as those in Figs. 32-36, but with the letter A attached.

The instrument 420A introduces two unmixed drugs into the uterine cavity and mixes them before being injected into the fallopian tubes.

The head at the top of the messenger is labeled 651, and underneath it there is a passage 652 which crosses both sides, allowing the drug to enter the upper part of the uterine cavity. Room 655 is located between these tubes and passageway 652 where drugs from two tubes, labeled 653 and 654 can be mixed. This mixing continues even within passage 652. Inside the housing 457A there are two rooms 656, which contain two containers (657 stores the drug 658 and 659 stores the drug 660). A piston 661 is connected to the rear of the vessel 657, and a piston 662 is connected to the rear of the vessel 658. This piston is connected to branch lines 663, 664 of the plunger 514 of the second actuator 479A, respectively.

The tubes 653,654 are connected to the needles 666,667, respectively, and they are positioned to connect with the containers 657,659, respectively.

When activator 468A is activated, first actuator 467A moves to slightly inflate sleeve 444A to block the lower portion of the uterine cavity, then second actuator 479A advances plunger 514A where extended branch line 663,664 extends piston 661,662 simultaneously. The drug in the container 657,659 enters 658,660 tubes, 653,654, into the room 655, almost 50% of it, and becomes a mixture 668, which is split along both sides of the passage 652, in approximately equal proportions, into the top of the uterine cavity. Mix-in proceeds until the operation of the plunger 514A is complete, and then as the operator 468A moves, the sleeve 444A injects the drug into the fallopian conduit 433A, 434A by expansion.

The two drugs 658,660 may be mixed to become a semi-rigid plastic. This mixture may adhere to moisture, body temperature or other stimuli in the tissue. This mixture requires a certain time for the fixation reaction and can be injected into the fallopian conduit before it solidifies.

Examples of this type include 2 part-epoxy, 2 part-tissue adhesives, silicone-RTVs, polymers such as Dow Corning's plastics and 382 medical elastomers and 360 medical fluids. There are many other drugs that are fixed while being mixed, and the mixing ratio can be varied accordingly by adjusting the size of the container in the apparatus.

39 shows the deformation mechanism 720 and the one inserted into the uterine cavity. The instrument 720 has a long messenger 741 that can be inserted into the uterine cavity 732 through the vaginal cavity 727. The balloon device 741 is mounted on the top of the messenger, and the balloon device has a sleeve 444. The top and bottom of the sleeve are tied together to form room 748. At the top of the reader, a plurality of holes 745 are drilled to connect the passage 742 and the room 748 in the inside of the reader. Sleeve 744 is a type of tube made of flexible, elastic rubber or plastic, and has a very weak surface tension when inflated.

Latex rubber or the like is a material suitable for a sleeve that is expanded by a relatively low pressure and does not have a strong surface tension. The material of the sleeve easily expands and fills in the shape of the interior of the uterine cavity so that no part is biased. When the sleeve 744 completely fills the uterine cavity, the surface of the sleeve is in uniform contact with the inner wall of the uterine cavity. Conventional balloon type catheters, however, are rigid and relatively elastic, and do not expand in the shape of the uterine cavity under low pressure. The tip of the reader is closed by the head 749, and there are passages penetrating from side to side to form an exit. The head 749 is connected to a long tube 753 through the inside of the speaker 741.

42-46 show a mechanism 754 in which the balloon inflation device and the drug injector are operated independently. The instrument 754 has a housing that is divided into a lower 756A and an upper 756B, which are coupled with various screws 760 and the like and have a small, maneuverable protrusion 755 at the rear. The housing can accommodate the parts. Room 757 is co-ordinated with the news 741. The tube 753 in the news extends into the interior of the room 757 and has a 761 needle tip.

In FIG. 39, the top of housing 756 has an opening 762 leading to room 757. This opening is long and wide so that the container 763 can fit inside the room 757. The container 703 is long cylindrical and the front is closed with a rubber plug 764. This container contains drug 767 and the container is in line with the needle 761. The long hole in the rear of the housing has a plunger 768, which is in communication with the room 757 and the plunger is located so that it can be connected to the rear of the container. There is a head 771 on the rear end of the plunger and on the outside of the housing so that it can be held at the time of use. The front end of the plunger is adapted to be connected to the piston 766.

Inside the housing 756 is another room 758, which has a cylinder 773, which is connected to tube 774 through the inner tube 742 of the reader 741. Thus, fluid such as air or water in the cylindrical container 773 can expand the sleeve 744 through the passage 742. Both tubes 774 and 753 are guided to the reader 741 and sealed 776 by welding and other methods. The rear upper end of the cylinder 773 has a hole 777 to allow air to enter the cylinder.

psi이다. 슬리브에 가해진 유체 압력은, 자궁강벽이 건강하면, 저항을 받아 상승하게 되나, 약하거나 병들어 있거나 헐어진 자궁벽과 팽대된 자궁은 슬리브를 안정시킬 수 없기 때문에 일정 압력을 유지시킬 수가 없게 되며, 이로서 이상 유무가 확인된다. 이러한 자궁의 검사는 약물을 투입하기전에 수행되어져야 한다.The rear end of the cylinder is closed by the piston 778. At the back of the cylindrical container 773 is an actuator device 779 connected to the piston and advancing it allows air in the container to expand the sleeve through the inner tube 742 of the reader along the tube 774. The activator device 779 can fill the uterine cavity by forming a constant pressure in the sleeve and can also check the abnormality of the uterine cavity. At this time, the ideal fluid pressure is 7 to

psi. The fluid pressure applied to the sleeve increases with resistance when the uterine cavity wall is healthy, but weak, diseased or broken uterine walls and the uterus that are swollen cannot maintain a constant pressure because the sleeve cannot stabilize. Abnormality is confirmed. This examination of the uterus should be performed before the drug is injected.

47-49, the activator device 779 has a cylinder 781 and the front of the cylinder has a conical groove 782 to allow the back of the conical piston 778 to enter. The inner tube 783 of the cylinder 781 is fitted with another cylinder 784.

On the outside of the rear of the cylinder 784 is a head 786 that can be gripped during operation. The front of the cylinder 784 is the front section 788 and the projection 787. The spring 789 in the cylinder 783 hangs on the support 788 and the top of the cylinder, pushing two barrels 781,784 together.

The pin 791 embedded in the hole 792 in the cylinder 784 is inserted into the slot 793 in the cylinder 781 and connects two 781,784 barrels. The slot is slightly longer so that the two cylinders can move little by little with the spring 789's elasticity. Will be.

psi) 유체와 슬리브의 압력은 합이 7psi-

psi가 되게 된다. 제 46 도에 도시된 바와 같이 핀 791은 하우징 756A에 있는 그루브 790에 끼게 되어 있어 활동자장치 779가 회전되지 않도록 한다.The elasticity of the spring is predetermined (preferably 7-

psi) The pressure of the fluid and sleeve is 7 psi-

psi. As shown in FIG. 46, the pin 791 fits into the groove 790 in the housing 756A to prevent the actuator device 779 from rotating.

In FIG. 49, barrel 784 has a cylindrical hole 794 in which a lock 796 is contained. The lock 796 consists of a cylinder 797 with a hole 797A on the inside, a forward projection 798 and a spring 799 inside the inner hole.

In the forty-seventh embodiment, there is a hole 701 in the upper portion of the cylinder 781. When the projection 798 and the hole 701 are in line with the cylinder 784, the protrusion penetrates this hole and is connected to the adjusting device 702.

46-50, this adjuster 702 has a body 703 longitudinally embedded in the barrel, the front of which has an elongated head 704 with a protrusion 706 protruding from the head.

In the center of the projection 706 is a hole 707 with a guide rod 708 inserted in it that extends backwards into the hole 709 of the housing 756A, which can also be fixed by pin 711. . The rod 708 is wound with a spring 712, which is held in a collar 713 mounted at the rear end of the bite and in the middle of the rod, which serves to push the body 703 forward.

As shown in FIG. 43, the fuselage 703 facing the activator 779 is sawtooth-shaped so that the projection 798 of the lock can be inserted when the activator 779 is at a certain point in the advanced state.

psi,에 도달하면, 원통 781이 유압에 밀려 더 이상 전진할 수 없게 되어 플런저 784에 있는 자물쇠의 돌기가 원통 781에 "걸린"상태가 된다. 이때 돌기는 동체 703의 톱니에도 동시에 걸려 활동자 779는 그 이상 움직일 수 없게 되고 유체의 압력은 스프링 789의 힘의 범위내에 머물게 된다.According to FIG. 42, both the plunger 768 and the actuator 779 are locked in an unused state by the lock 718. FIG. The lock 718 is connected to the housing and is inserted into a hole in the back of the plunger 768 and the operator 779 to secure them and, when used, to disinfect the instrument together with the cylinder 763. Deeply insert the contracted sleeve into the uterine cavity through the vaginal cavity and cervix so that the head 749 of the reporter is in close contact. Then, the lock pin 718 is pulled out and the activator is activated to check for abnormalities in the uterine cavity. Advancing the actuator device 779 pushes the plunger 784 into the barrel 781 and pushes the piston 778 into the cylinder 773. Fluid from the reservoir in the cylinder 773 enters the sleeve 744 along the inner tube 743 of the operator 741 via the tube 774. As shown in FIG. 39, the sleeve expands until the uterine cavity 732 is completely filled. Part of the sleeve then enters the mouth of the fallopian conduit. The sleeve is flexible and elastic, so it expands and fills the shape of the uterine cavity. Continued advancement of the plunger 784 of the operator 779 further raises the hydraulic pressure in the balloon. Once the desired pressure, 7-

When psi, is reached, the cylinder 781 is pushed by the hydraulic pressure so that it can no longer move forward and the lock on the plunger 784 is "locked" to the cylinder 781. At this time, the projection is caught by the teeth of the fuselage 703 at the same time the activator 779 can not move any more and the pressure of the fluid stays within the range of the force of the spring 789.

If the passage of fluid leaks or the uterus is weak, the sleeve cannot be held constant. If an abnormality occurs in the uterus, the spring 789 cannot be resilient and the lock cannot coincide with the hole 701. When the force applied to the activator is removed, the activator retreats to its original position. If there is a hole in the fluid passage, the actor may advance until the head 786 connected to the actor reaches the housing.

) 활동자 장치 779는 후퇴하며 이에 따라 슬리브내의 유체압력도

정도로 떨어지게 되어 슬리브가 수축되는데 수축된 슬리브는 자궁강의 하부를 밀폐할 수 있을 정도의 탄력을 갖고 있다.However, if the uterine cavity is strong, the cylinder 781 will retreat relative to the advancing plunger 784, causing pin 89 to "snap" into the cylinder 703. This shows that the uterine cavity is strong and the sleeve is fully inflated. If the uterine cavity is weak or there is an abnormality in the fluid passage, no such sound is produced and the pin cannot connect the activator device 779 to the fuselage 703. However, once the actor is connected to the fuselage 703 by a pin, the force of the spring 712 holding the fuselage is weak (

The activator device 779 retracts so that the fluid pressure in the sleeve

It is dropped to such a degree that the sleeve contracts, and the contracted sleeve is elastic enough to seal the lower part of the uterine cavity.

Referring to FIG. 44, the plunger 768 once pushes the vessel toward the needle tip to make a hole in the plug 764, and then pushes the piston forward so that the drug exits through the tubes 753 to both exits 767A, 767B along the tube 753. This leads to the top of the sleeve that has been shrunk in half (see Figure 4).

psi가 된다. 팽창된 슬리브는 자궁벽에 완전 밀착되기 때문에 약물이 그 사이에 전혀 개재하지 않는다.Once the drug is introduced into the uterine cavity, the activator device 779 is slowly advanced again as shown in FIG. 45 to inflate the sleeve back to its original expanded state so that the injected drug is injected into the fallopian conduit 733, 734. . At this time, the fuselage 703 is filtered by the battery unit 704, and the active body 779 connected to the fuselage can not move further, and the pressure of the fluid is

psi. Since the inflated sleeve is completely in contact with the wall of the uterus, no drug intervenes therebetween.

Using a tissue adhesive of cyanoacrylate preparation, it causes polymerization with moisture of living tissue, destroying the cells, and the fallopian tubes are closed forever by the new fibrous cells.

Loosening pin 711 releases the bundled guide rod 708, retracting the fuselage 703 and the operator 779, and shrinking the sleeve 744. After this, the sleeve is removed from the uterine cavity.

FIG. 51 shows a female genitalia 821 with a 820 and a female inserted into a modification of the medication device. Genital 821 has uterus 822, two fallopian tubes 823,824, under the uterus has a long elongated vagina 827, vaginal sphere 828. The upper part of the vaginal cavity is connected with the cervix 831 and the vestibular 832 of the cervix is opened. Fallopian tubes 823,824 each have a conduit 833,834, which is connected to the upper ends of the uterine cavity. Fallopian tubes are long, trumpet-shaped muscle tissue that connect the ovary with the top of the uterine cavity.

The entrance to the catheter is different in location depending on the uterus, and the size varies from woman to woman. The catheter acts as a pathway for carrying the egg from the ovary to the uterine cavity.

Uterus 821 consists of 836 uterine base and uterine interval 837,838 surrounding the uterine cavity. The uterus is covered with membrane 838, which is peeled off and removed at regular intervals.

The dosing device 820 has a long messenger 841 that can be inserted into the uterus 832 via the vagina 827. The messenger has a collar 842 that can control the length of the messenger 841 entering the uterus 832.

The sleeves on top of the reader 841 are screwed up and down to form a single room 869 and the holes are perforated with multiple holes, allowing fluid to pass from the reader to the room 869.

Sleeve 844 is a tube made of flexible, elastic rubber or plastic, intended to expand. Low surface tension allows latex rubber to expand evenly even under low pressure, making it suitable for sleeves.

The sleeve expands in the form of the uterus by low pressure and does not form a partial pressure. When the sleeve expands partially or fully, it closes to the wall of the uterine cavity. Conventional catheters are rigid and do not expand under low pressure to match the shape of the uterine wall.

The injection unit 846 is connected to the rear end of the operator. The injector section has a housing 849 and a handle 851,852 with two housings 853,854 in the housing, with passages 856,857 connected respectively. This passage communicates with 856,857 all news 841. Between the two chambers 853,854 there is another vessel 858, which is intended to be connected to a tube 859 penetrating the inside of 841.

Tube 859 has an outlet 861 that exits the balloon apparatus. Three plungers 862,863,864 can be operated to apply force to the vessels 853,854,858 and their own objects or drugs are put into the sleeve and uterine cavity 832, respectively. The plungers 862,863 and 864 each have separate manual locks 866,867 and 868 to lock the plungers in the inoperative position.

Drugs are injected into the fallopian tubes by the expanding sleeve when the sleeve expands inside the uterine cavity 832. Among the drugs used are temporary blockage of the fallopian tubes. After a period of time, the catheter is reopened and normal function is restored.

In practical use, instrument container 853,854,858 is inserted and the retracted sleeve 844 is inserted into the uterus of the patient. The inserted sleeve may be placed in the center of the uterine cavity or may be omnipresent, but there is no problem in injecting the medicine into the fallopian tubes.

After that, it expands by injecting a fluid such as air or liquid into the sleeve and expands only slightly as the sleeve seals the lower part of the uterine cavity. This is done by releasing the lock 866 and advancing the plunger 862 so that the fluid in the container 853 enters the sleeve along the news 841. The sleeve 844 is of low tension and applies uniform low pressure to the uterine cavity so that the sleeve 844 adheres uniformly to the lower wall of the uterine cavity without forming partial pressure.

The sleeve 844 can be fully inflated to measure the size of the uterine cavity, and slightly contracted to leave space in the sleeve, the top and the uterine base (Figure 51).

The lock 867 is then released to advance the plunger 863 to direct a certain amount of drug in the container 858 through the tube 859, to the tip of the newsr, into the space of the sleeve and the uterus and apply a little pressure.

The sleeve is further inflated so that when the inflated end of the sleeve comes in contact with the cervical canal, the injected drug splits to about the same shape on both sides (FIG. 52).

As shown in FIG. 53, when fluid is further injected into the sleeve and expanded, the sleeve fills up to the inlet of the conduit to inject the drug into the fallopian tube by low pressure. In other words, the sleeve under expansion serves as a pump, but the sleeve is in close contact with the membrane so that almost all of the drug is injected into the fallopian tube during pumping.

Tissue adhesives of cyanoacrylate preparations cause polymerization with moisture in living tissues, resulting in the destruction of cells to form fibrous tissue, which permanently closes the fallopian conduit.

The sleeve is then shrunk as shown in FIG. 51 and a second fluid, such as water, is introduced into the uterine cavity to dilute and wash the remaining adhesive. The sleeve is then fully retracted to remove the instrument from the uterine cavity.

FIG. 54 shows a longitudinal cross-sectional view of the female genitalia 920 with a catheterized instrument 921 inserted therein capable of injecting a fallopian tube with drugs, tissue adhesive, water, contraceptives or similar substances.

The genital 920 has a long vaginal cavity 922 surrounded by the vaginal wall, which is open to the vaginal opening 924. On the other side of the vaginal opening is the uterus 926, in the uterus there is a uterine cavity 927, and in the upper part of the uterine cavity there is a uterine base 928. The lower part of the uterus has the cervix 931, which is the demarcation point between the uterus and the vagina. The inner wall of the uterus contains a thin film that periodically transforms, and the fallopian tube serves as a pathway for carrying the egg from the ovary to the uterus.

The long catheter 938 is connected to the injection device 921 so that it can be inserted into the uterine cavity 927 through the vagina 922. The inflatable inflatable sleeve 939 is mounted on the top of the catheter 938 by bands 940A, 940B. The band 940A attaches the top of the sleeve 939 to the top of the catheter 938 and the band 940B attaches the bottom of the sleeve. Sleeve 939 is a resilient cylinder made of flexible rubber. The material of the sleeve is one having uniform surface tension and uniform expandability.

When the sleeve 939 is inflated, the sleeve 939 uniformly fits almost all over the wall of the uterine cavity regardless of the size or shape of the uterine cavity. Due to this characteristic of the sleeve, the same type of sleeve can be used for various types of uterine cavity.

Sleeve 939 forms a room therein. The catheter has a number of holes that allow fluid in the catheter to enter the inner 941 of the sleeve. The top of the catheter is plugged with plug 943. The plug 943 is also connected to the elongated tubes 944, 946 and the drug in the tube enters the uterine cavity via exits 944 A and 946 A perforated in the plug. The end 946A of the tube 946 is inclined so that fluid once injected into the uterine cavity cannot flow back into the tube 946.

The middle portion of the catheter 938 has a circular collar 947, as shown in FIG. 54, which supports the cervix and prevents the sleeve attached to the catheter 938 from entering too deeply. In other words, the collar creates a space between the sleeve and the uterine base. Thus, when the sleeve first expands, it almost expands in the lower part of the uterine cavity, but space remains in the upper part of the uterine cavity connected to the fallopian tubes.

When the sleeve is inflated, the catheter comes up, but is supported by the collar hanging on the cervix, and the sleeve is more tightly attached to the lower uterus. Fluid flows over the uterine cavity and is injected into the fallopian conduit.

54 and 55, the bottom of the catheter is connected to the injector section 948, which inflates the sleeve once by injecting fluid such as air or water into the catheter 938 in one step, and then expands the sleeve. In the second step, the fluid such as drug is introduced into the upper uterine cavity through the tube 944, and the fluid such as water is introduced into the uterine cavity again through the tube 946 by the three-stage operation so that the drug introduced in the second stage can enter the fallopian conduit well. Or make it solid.

Referring to FIG. 55, the input device portion 948 has a housing 949 and there are three rooms 951,952,953. All of these rooms are arranged side by side, but can also be arranged vertically in parallel.

The first passageway 954 in the housing connects the first chamber 951 and the catheter 938, the second passageway 956 connects the chamber 953 and the tube 946, and the tube 944 connects to the chamber 952.

The container 957, shown in FIG. 57, is a cylinder capable of containing fluids such as water, air drugs and the like, with a head 971 at its front end and a plug 972 therein. The back of vessel 957 is closed by piston 974 and the piston is connected to plunger 973. At the rear end of the plunger 973, the protrusion 976 protrudes horizontally. This projection is arranged in the circular spring 977 which extends over the outer edge part 968 of the container 957 and the projection 976, and presses a container and a plunger mutually.

The inside of the plunger 973 has a cylindrical hole 979 at the rear, and an activator rod 981 is inserted therein. The front of the rod has a long hole 982 perforated with a spring 983 connected to the plunger inner tube 979. The spring 983 presses the plunger and the actuator rod 981 together.

In housing 949 there is a first activator 984 which is arranged to be movable, which is connected to the activator rod 981. The vessel 957, connected to the cotton plunger 973 in the direction of arrow 985, is first pushed forward by springs 983 and 977 so that the needle drills a hole in the front plug 972 of the vessel. Along the needle passes through passage 954 into the inner tube of the catheter 938 to inflate the sleeve 939. At this time, the pressure of the fluid depends on the spring 983,977, low pressure and uniform.

Actuator 987 is connected to vessel 959, where the fluid is forced out in a similar manner. Between the two actors 984,987 is the actor 988, the fluid in the vessel 958 connected to it is introduced into the uterine cavity along the tube 944.

Trigger 989 is designed to trigger actors 984,988 in turn. The trigger is located at the back of the housing and can be connected to the actor, with the lever lever extending down along the handle. There is a hole in the middle of the lever and it is pinned to the hole under the housing. At the top of the lever, the head 994 of the cylinder is collinear with the actor. The spring 996 is fixed to a part of the housing and is to be mounted back to the lever head (FIG. 56).

The head 994 has a hole drilled from side to side with a spring pin 910 in it, and two holes 997,998 drilled back and forth so that the plungers 988,987 can be inserted respectively. Pin 901 has a thin neck portion 902, where the first plunger rod 984 is caught in the neck when the instrument is in an inoperative state such that the actors 987,988 are not caught by the head 994.

In FIG. 55, the grooves 912, 911, 909 are cut in the activator rods 987, 988, 994, respectively. In FIG. 56 and 54, three locks 921, 913, 919 are provided. Each of these locks is able to protrude downwards and is locked by a C-shaped ring when the instrument is not in use. Release the C-ring and pull the trigger to advance actor 984, which triggers 919 to descend and hit home 909, which in turn is triggered by trigger 913 and actor 987 by trigger 921, respectively.

By 58,59,60 degrees one can see that the trigger advances the actors 984,988,987 one after the other. An end projection 907 of the actor rod 984 is inserted into the neck 902 of the pin in its original position.

Pulling the trigger lever to advance the head causes only the rod 984 to advance so that the lock 919 is in the groove 909 in the middle of the rod, and when the head is retracted, the pin 901 extends to the left to place the rod 988 in a position to squeeze it. When the head is advanced again, the rod 988 is locked by the lock 913. When the head is retracted, the pin extends to the left end to press the rod 987, and when the head is advanced, the rod 987 is caught by the trigger 921.

The vessel 958 shown in FIGS. 55, 61, 62, and 63 is a long barrel, the wall of which is made of a resilient metal such as lead or lead alloy, and is capable of sealing the fluid. The container 958 stores moisture sensitive drugs such as tissue adhesives. The container must be made of a material that will prevent any elements that hold fluid such as moisture.

The front of the container 958 has a head 922 extending in a cylindrical shape, the head of which is sealed with a membrane 923. The vessel's torso 924 has a sharp tip. This container 958 is placed in room 952 with the head of the container facing the needle and the body of the container facing the wall of the room. Both walls of the room are angled to narrow the inside of the barrel. Spring 929 is caught between the bottom of the barrel and the head of the container. The front of Actor 988 is bifurcated with its bifurcated limbs being flexible and bulging inside.

As the activator 988 moves forward, the two legs are pushed against the wall of the barrel to advance the container, allowing the needle to penetrate the membrane of the head. This tube 944 injects the drug into the uterine cavity as shown in FIG.

In use, the apparatus 921 performs one method of injecting drugs such as tissue adhesives, contraceptives, into the fallopian tubes. In the method of use, a catheter with an inflatable sleeve is first inserted through the cervix into the uterine cavity. At this time, the sleeve is inserted in the middle of the collar collar is caught in the neck is slightly away from the base of the uterine cavity to form a space.

The sleeve 939 initially expands to a certain degree under the pressure of the first fluid and is uniformly in contact with the lower part of the uterine cavity to seal the uterine cavity because the collar cannot enter deeper when inflated.

Pulling the trigger back to advance the actor 988 advances the container and connects the container with the needle, and fluid such as tissue adhesion stored in the container is introduced into the upper portion of the uterine cavity along the tube 944. When the trigger is pulled again, the activator 987 advances and fluid such as water in the container 969 is also introduced into the uterine cavity to act as a carrier for injecting the previously introduced drug into the fallopian tube. The liquid injected from the vessel 959 may polymerize or adhere the drug injected in the vessel 958 to close the conduit. Drugs that remain in the uterine cavity can be removed by conventional methods because they are fully polymerized and do not adhere to the uterine wall. Unlocking the lock 919 allows the activator 984 to retreat, allowing the fluid in the sleeve to retract into the container 957, contracting the sleeve, and allowing the catheter to be removed from the uterus.

Another dosing instrument 1020 is inserted in the uterus 1021 in FIG.

Uterine 1021 has the uterine cavity 1022, the upper part of the uterine cavity there are fallopian tubes 1023,1024, these fallopian tubes contain the conduit 1025, 1026, respectively.

The instrument 1020 is a uterine catheter capable of injecting drugs such as direct attachment into the fallopian tubes. The instrument has an injector section 1027 and a long mediator 1028 that can inject fluid from the device section into the uterine cavity. The news is long and can be inserted into the uterine cavity.

In FIGS. 64 and 65, this instrument 1020 has an elongated housing 1029 and therein an elongated room 1031. A long groove 1032 is dug into the top of the housing, acting as a door to room 1031. At the rear of the housing is a long hole 1033 extending from the room with a plunger 1034 inserted. The rear end of the plunger has a disc head 1036 and a head 1037 at the front end. On the outside of the housing aft are two projections 1038,1039, which allow the person using the instrument to hold the finger with the fingers and operate the plunger head forward. There is a groove 1041 in front of the hole in the rear of the housing so that the plunger head 1037 is fully inserted when the plunger is retracted to the rear end of the groove 1032.

The container 1042 for storing the fluid can be inserted into the room 1031 through the groove 1032 on the housing. The container is cylindrical and the cut is mounted in band 1046, with plug 1044 in it. The plug is made of rubber and can be drilled with a needle. The rear of the container contains a plug 1047 to seal the container. The plunger head 1037 is adapted to be connected with this plug. Advancing the plunger 1034 initially moves the entire container toward the needle. The reader 1028 device had a tube 1049 and the inside of the tube was called an inner tube 1050.

As shown in FIG. 66, the tube 1049 extends long from the opening of the base 1051 connected with the housing 1029, which base encloses and slightly extends the tube 1049 and the end 1053 is narrowed conical. Along the center side of the tube 1050 is another guide tube 1054, which has a plug 1056 at the end to secure the guide tube 1054 to the center of the tube 1050 and to close the tube 1050 at the same time.

68-70, the balloon device 1057 hangs outside the end of the tube 1049. The balloon device is attachable and detachable so that there is a long sleeve 1058 inside the balloon device 1057, one side of which is open toward the tube 1050 and a plurality of holes 1059 are installed to allow fluid to pass therethrough. A thin elastic membrane 1060 wraps around the sleeve 1058 and forms a chamber 1061 to contain the fluid. Membrane 1060 is elastic and expands and contracts and does not stretch. Latex rubber is one of the good materials for this membrane. The membrane is folded inward on the outside of the tube 1049 to maintain its center upon expansion. The end of the guide tube 1054 is inserted into the cutting groove 1067 of the sleeve end. The round ring serves to secure the guide tube 1054 and the sleeve 1058.

In Figure 64-71, one tube 1069 runs through a plug 1056 through a tube 1050 with an nipple 1071 at its end. The pump 1072 is used to inject air into the nipple. The pressure gauge 1073 is connected to the pump and is connected to the nipple by a long tube. In addition, a valve 1076 is installed to exhaust air from the device. The pump may be in the form of a syringe or cylinder. A fluid such as water may be used to expand the membrane 1060. The pump 1072 is operated to inject fluid into the tube 1050 and the fluid entering the tube enters the room 1061 of the membrane 1060 through the hole 1059 to expand the membrane. Referring to FIG. 64, a membrane of expandable material expands to fill the uterine cavity 1022.

65-66 degrees, Carver, marked 1077, encloses the coffin 1049 and act 1060, which is a one-time use that could be called. Carver 1077 is a balloon made of a material with low surface tension, such as latex rubber, connected to coupling device 1078.

Long tubular needle 1084 is encased in guide tube 1054. 68-69, the outer end of the needle 1084 is coupled to the carver 1077 by an inner member 1086 and a washer 1087. The rear end of the needle is open or inclined to fix the member 1086 and washer 1087 to the carver 1077. The Washsha 1087 fits into the groove in the center of the sleeve 1058. The accessory of the 1086 is inserted into a groove 1089 inside the tip of the sleeve, with the end of the 1086 and the bottom of the groove being conical to each other.

The inner portion 1092 of the needle extends into the room 1031 and the tip 1093 of the needle is arranged on the same side as the plug 1044 of the container 1042. Inside the needle there is a shoulder 1094, which holds the needle in the housing and simultaneously secures the carver 1077 to the sleeve 1058.

A variant of a disposable carber 1096 is shown in FIGS. 72-73. Carver 1096 is a long tube made of material 1097 such as polystyrene film or elastic rubber.

The front end of this carver is tied and the back is attached to the coupling device 1098. The coupling device 1098 is identical to the coupling device 1078 shown in FIGS. 65-66. The material 1097 of the carver 1096 has many wrinkles such that the surface tension does not increase as the carver expands. The corrugation is like 1101 in FIG. 73 so that the expansion of the carver does not increase the surface tension at all. The head of the needle holds the carver in the shape as shown in FIG. The needle is connected from the coupling device to the inside of the housing.

One variation of the pleats is shown in FIG. 77. This wrinkle extends in the longitudinal direction as the wrinkle of FIG. The width of the pleats can be changed and the shape of the carver is adjusted accordingly. Wrinkles become pear-shaped when inflated.

66,74 and 76 degrees, the hook 1094 is hooked to the needle 1084 at the hook 1106. The hook 1106 is upright in the groove 1107 in the front of the housing 1029. Part of the top of the device allows the support 1094 to be accessible from the rear.

Under this collar 1106 there is a groove 1107 into which a spring 1109 can be inserted and a spring is placed on the bottom plug 1111 to push the collar 1106 back.

On top of collar 1106 is hand-operated activator 1113. This activator has an anteriorly extending projection 1114 and at the end of this projection there is another projection 1116 that projects upwards. This protrusion 1116 serves to couple the coupling device 1078 to the housing 1029.

Underneath this actor 1113 is a groove 1118, which contains a spring 1117, which rests on part of the spring tube 1049, pushing the actor 1114 upwards. Referring to FIG. 75, legs 1119 and 1121 are installed under the operator 1113, and the legs are engaged with the upper end of the ring device 1106. Referring to FIG. 76, pressing down the actor 1113 also moves the hook 1106 connected below, and the protrusion 1116 is disengaged from the protrusion 1082 of the coupling device so that the coupling device can be detached from the sleeve 1052 and at the same time the holding member 1094. Also released from ring device 1106.

Once the needle is fully inserted, the member 1086 is also inserted into the groove of the sleeve 1058, as in FIG. 68,69. In use, the plunger 1034 is fully retracted so that the plunger head 1037 is inserted into the groove 1041 and then the container is inserted through the slot 1032 into the room 1031. Advance the plunger so that the head 1037 is connected to the plug 1047. At this time, the position of the head 1037 is partially entered into the cylindrical container. The container 1042 is thus fixed in the room with the needle and plug 1044 arranged on the same side and the distance between the plug 1044 and the needle being maintained by the spring 1095.

Room 1077 may be packaged separately in a sterile container. One side of the vessel is openable to allow the carver to be coupled to the tube 1049. The cover and the needle are packaged as a sterile disposable set.

Insert the needle into the guide tube 1054. Move the coupling and needle into tube 1049 until coupling 1078 is in sleeve 1052. The projection 1116 moves the projection 1082 of the coupling device until the coupling device and the housing 1029 are engaged. Move the outer side of 1077 until the cocoon 1106 is in the groove 1089.

A hose 1074 is connected to the nipple 1071 to allow the member 1072 to supply air to the room 1050 under pressure. Tube 1074 may be applied to nipple 1071 before the container is loaded into the housing.

In use, the container or the packaging for the cover is removed. The carver is introduced into the uterine cavity through the cervix together with the tubes in the carver. Pump 1072 supplies air to passage 1050 under pressure, and air in passage 1050 flows into room 1061 through outlet 1059. The room expands to a flexible material area, increasing in size, and the flexible area expands to the outer end of the carver to fill the uterine cavity. Carver is made of a material with low tension and elasticity which gives uniform and low pressure to the inner wall of the uterus. The carver and the flexible area are shaped like a uterine cavity so that the carver's distal position is at the top of the uterus. Sleeve 1060 expands to the expected pressure indicated by gauge 1073 with air under pressure and gauge 1073 continuously indicates the air pressure of sleeve 1060 to maintain a constant pressure in the uterine cavity and the sleeve fills the uterine cavity. In addition, the air in the sleeve 1060 does not leak by indicating the air pressure.

Drug 1084 in container 1042 is injected into the uterine cavity between the expanded carver and the uterine wall. Housing 1048 is pushed by gripping protrusions 1038 and 1039. Head 1037 acting with plug 1047 acts to add vessel 1042 to nipple 1084. The distal end 1092 of the nipple penetrates the plug 1044 so that the drug can flow through the nipple to the outer end of the carver. The nipple through plug 1044 is cleaned clean. The drug flows between the carver and the top or base of the uterus and enters fallopian tubes 1024 and 1026. The drug may be a tissue adhesion agent, such as a cyano acrylate monomer. When the plug 1047 reaches the head of the cylinder 1043 by moving the plunger 1034, the drug 1048 is injected into the uterine cavity through the nipple 1084.

The instrument 1020 is removed from the uterine cavity by releasing air pressure from the sleeve 1060. This is done by opening valve 1076. By reducing the pressure, the sleeve 1060 can be reduced in size to remove the carver from the uterine cavity. The manual operator 1113 is pushed out of the housing 1029 to disengage the Carver 1077 from the housing. This leaves protrusion 1116 from protrusion 1082 and leaves ring 1106 from portion 1094. Nipples 1084 and carver 1077 can be removed from tube 1049.

Some types of medications are birth control pills that have minimal effects on the fallopian tubes and uterus. For example, microcircular contraceptives that can be absorbed in vivo, such as projectionin, can be administered through the fallopian tubes. Microcircular medications disintegrate over a period of time (for example, one year) and during this time contraception.

Biological agents (eg, soluble fiber enzymes) can also be administered into the fallopian tubes and uterine cavity to treat tissues. These biological agents are used to treat inflammation around the fallopian tubes.

Diagnostic agents can also be injected into the fallopian tubes by the instrument of the present invention. Such agents include oily and aqueous X-ray dyes and pigment support agents such as methylene buru and indigo calmine and the like.

Analgesics can also be injected into the fallopian tubes by the apparatus of the present invention.

You can also introduce drugs that move eggs and sperm into the uterus and fallopian tubes. These drugs expand or dilate the fallopian tubes or their pathways so that they are well conceived. In recent years, there are several kinds of drugs that are administered to the fallopian tubes to promote conception. Anti-inflammatory agents, such as cold decoys, can be used to treat inflammation in a small way, and antibiotics can also be used to treat inflammation of the fallopian tubes in a very small way. Sperm may not move through the cervix and uterine cavity or may be blocked and become infertile. The instrument of the present invention is to cut the sperm into the uterine cavity and fallopian tube to better conceive.

Claims (1)

An elongate member 38 supporting the expandable sleeve member 39 at or near the lateral end that may be arranged to expand within the uterus and injecting material through the passage of the elongated member into the uterine cavity and inflating the expandable sleeve member In the female fallopian tube injection mechanism consisting of an injection portion 44 attached to the tartan portion of the elongate member, injection portions 51 and 53 are provided for rapidly injecting a substance such as a drug into the uterine cavity. A single actuating mechanism 47 for inflating the expandable sleeve member 39 is connected to the injection section 44 such that the material injected by the injection sections 51 and 53 is transferred from the uterine cavity 27 to the fallopian tube. An instrument for intrauterine administration, characterized in that it is configured to move quickly by the inflation surface of the expandable sleeve member (39) into (36,37).

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