KR20130071857A

KR20130071857A - Water tissue, disposable absorbent products compring extracts of polygonum tinctorium and dendropanax morbifera & manufacturing method thereof

Info

Publication number: KR20130071857A
Application number: KR1020110139314A
Authority: KR
Inventors: 원효정
Original assignee: 원효정
Priority date: 2011-12-21
Filing date: 2011-12-21
Publication date: 2013-07-01

Abstract

PURPOSE: Wet tissue and disposable absorbent articles including extract of Polygonum indigo and Dendropanax morbifera as an active ingredient are provided to have the antibacterical activity and ammonia gas adsorption, and to have an excellent effect on prevention and treatment of skin diseases including atopic dermatitis, contact dermatitis and diaper eczema. CONSTITUTION: Wet tissue and disposable absorbent articles including extract of Polygonum indigo and Dendropanax morbifera as an active ingredient includes extract of at least one between Polygonum indigo and Dendropanax morbifera. In case of the mixing extract including both Polygonum indigo and Dendropanax morbifera, the extract extracted with mixing any one between Polygonum indigo and Dendropanax morbifera at 10-70 weight% compared to the other one. [Reference numerals] (S100) Preparing and washing leaves, fruits, skins, and roots of indigo plant and Dendropanax morbiferus; (S200) Crushing; (S300) First extraction; (S400) Second extraction; (S500) Spraying or dipping extracts; (S600) Packaging products

Description

Water wipes and disposable absorbent products containing the extracts of Hakchi and Hwangchil wood as active ingredients and methods for preparing the same

The present invention relates to wet wipes and disposable absorbent products comprising the extracts of spinach and yellow lacquer tree as active ingredients, and methods of manufacturing the same. In particular, the extracts of spinach and yellow lacquer tree are used for disposable absorbent products or wipes such as diapers and hygiene products. By impregnating a nonwoven fabric or cloth, etc., the present invention relates to a wet tissue and disposable absorbent product comprising the extract of Hwangchil-tree as an active ingredient and a method of treating and preventing skin diseases.

Disposable absorbent products are products that absorb body fluids excreted by various physiological actions, that is, products that receive urine and feces secretions, menstrual secretions and vaginal secretions. Disposable diapers used by infants or adults, menstrual articles such as sanitary napkins and vaginal inlets, urinary incontinence inserts and pantyliners.

In addition, there are wet wipes and the like, which will be described below by including wet wipes in a disposable absorbent product.

The performance of the disposable absorbent product is primarily evaluated by the amount of absorption and the rate of absorption of the body fluid secreted by physiological action, but in the field of absorbency and absorption rate, many developments have been made by the development of super absorbent polymers. lost.

The next performance to be absorbed should be a product that can effectively prevent and treat skin rashes, dermatitis, etc., which can be caused by the use of diapers in body fluid excretion.

In addition, it should be a product excellent in the healing effect of skin lesions that have already occurred by wearing a disposable diaper against diaper rash or diaper dermatitis caused by wearing a diaper.

Disposable absorbent products consisting of conventional liquid permeable top sheets, downy pulp and liquid impermeable back sheets, after the product has been wetted with urine or body fluids, the urea in the urine is decomposed by microorganisms and enzymes present in the stool or skin to produce ammonia and In addition, the skin irritation caused by ammonia produced by the decomposition of urea and the chemical and physical skin irritation caused by the raw materials of the product itself are combined to cause diaper rash, red spots and skin inflammation.

The root cause of diaper rash can be attributed to the hydration of the skin's stratum corneum due to the water generated during fluid excretion, continuous friction between the diaper and the skin, and secondary infection by microorganisms.

In addition, a healthy woman's vagina has an acidic pH of about 3.5 _to 4 to act as a self-cleaning action to prevent pathogens from breeding into the vagina.

However, when abnormalities occur in the vaginal acidity, pathogens, etc., invade the vagina, resulting in odor in the cold, which is a vaginal secretion, and the secretion of hypothalamus is increased.

In addition, when this cold hypothermia is severe, it is necessary to prevent such a problem because a bad odor enough to feel the smell to people around due to a large amount of cold.

Therefore, there is no irritation than conventional synthetics, so it has excellent stability to the skin and effectively reduces skin rash and dermatitis, and is a disposable absorbent product that can suppress or prevent rash or dermatitis that may occur after wearing the product. I really need it.

The present invention has been made to solve the conventional problems as described above, the main object of the present invention includes the extract of the side and the Hwangchil wood as an active ingredient to treat skin diseases such as atopic dermatitis, contact dermatitis and diaper eczema and the like The purpose of the present invention is to provide a wet tissue and disposable absorbent products comprising the extracts of Hwangchilchi and Hwangchilchi as effective ingredients.

Still another object of the present invention is to provide a method of manufacturing wet wipes and disposable absorbent articles as described above.

In order to achieve the above object, the wet tissue and disposable absorbent products and methods for preparing the wet tissue comprising the extract and Hwangchil-tree extract as an active ingredient having a skin disease treatment and prevention effect of the present invention,

According to the present invention as described above, the water stop and disposable absorbent products containing the composition comprising the extract of the side and the Hwangchil wood as an active ingredient has antibacterial and ammonia gas adsorption, as well as atopic dermatitis, contact dermatitis and diaper eczema, etc. Excellent effect on the prevention and treatment of the same skin diseases can be obtained.

In addition, the impregnation rate of the extract can be increased by impregnating the flow of a microcurrent in the process of impregnating the extract according to the present invention in the manufacture of water and disposable absorbent products.

1 is a view showing a manufacturing method of wet wipes and disposable absorbent products comprising the extract of the side and yellow chile wood according to the present invention as an active ingredient.

While the invention is susceptible to various modifications and alternative forms, specific embodiments thereof are shown by way of example in the drawings and will herein be described in detail.

It should be understood, however, that the invention is not intended to be limited to the particular embodiments, but includes all modifications, equivalents, and alternatives falling within the spirit and scope of the invention. Like reference numerals are used for like elements in describing each drawing.

The terms including ordinal, such as second, first, etc., may be used to describe various elements, but the elements are not limited to these terms.

The terms are used only for the purpose of distinguishing one component from another. For example, without departing from the scope of the present invention, the second component may be referred to as a first component, and similarly, the first component may also be referred to as a second component. And / or < / RTI > includes any combination of a plurality of related listed items or any of a plurality of related listed items.

The terminology used herein is for the purpose of describing particular example embodiments only and is not intended to be limiting of the present invention. Singular expressions include plural expressions unless the context clearly indicates otherwise. In this application, the terms "comprise" or "have" are intended to indicate that there is a feature, number, step, operation, component, part, or combination thereof described in the specification, and one or more other features. It is to be understood that the present invention does not exclude the possibility of the presence or the addition of numbers, steps, operations, components, components, or a combination thereof.

Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries are to be interpreted as having a meaning consistent with the contextual meaning of the related art and are to be interpreted as either ideal or overly formal in the sense of the present application Do not.

Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings.

The present invention relates to a wet tissue and a disposable absorbent product comprising a extract of polygonum tinctorium and extract of dendricox morbifera as an active ingredient and a method for producing the same.

The green grass is a vegetation called the plant containing the indican which produces the indigo which is used for the preparation of the dye for the dyeing, and is cradle, mountain grass (Ezo woad), Ezo woad (Cruciaceae) ), Mountain grass (Daegukdae), and South Indian (印度藍).

Hwangchil-tree (Dendropanax morbifera) is an evergreen tree belonging to the arboraceae family, and can be found in some islands in the southern coast of our country. It has been used as a lacquer for furniture (Lee Chang-bok, Korea Plant Book, Hyangmunsa, 1982).

Hwangchil-tree was used so dearly that the Chinese Tang Dynasty sent him to Baekje to save it.In the herbal tree, written by Ming Yi Si-jin, Hwangchil-tree was removed (heavy fever in the body, tingling in the chest and painful symptoms), It has been described to be effective in the treatment of alcohol detoxification, eye and jaundice, burn treatment, and leprosy (Lee Si Jin, Herbal Medicine, Chinese Moonlight Book, 1590).

As described above, it is expected that various pharmacologically active substances will be present in the yellow lacquer considering the durability of the yellow lacquer tree for medicinal use and the durability of the lacquered wood products in the form of preserved original form in old ruins. , et. al., Bull.Chem. Soc. Japan, 62: 2977, 1989; Terada, Chemistry, 45: 851, 1990).

Besides lacquer, unlike lacquer, it can be widely used as food as well as medicine because it is easy to handle and causes little skin allergy.

Therefore, the separation of the pharmacologically active substances contained in the Hwangchil wood not only can be used in medicines, etc., but also extracts of the Hwangchil sap containing pharmacologically active substances such as ginkgo biloba extract, ginseng extract and the like can be used in various products.

As described above, the yellow peach lacquer can be used as a medicinal product to separate certain ingredients from the yellow lacquer due to its pharmacological action, and unlike lacquer, it can be easily handled without causing any skin allergy. It can be seen that it can be widely used as a composition of the absorbent product.

In particular, about 90% of the components of the hwangchil is sesquiterpene (sesquiterpene) is known, the sesquiterpene is a compound having 15 carbon atoms are classified into a ring, monocyclic ring, bicyclic ring, tricyclic ring, etc. Some substances of sesquiterpenes are known to exhibit pharmacological action.

Specifically, the dried bark (polygonum tinctorium) and yellow bark (Dendropanax morbifera) bark or leaves and seeds of methanol (MeOH), ethanol (EtOH), propanol (propanol), methyl ethyl ketone, To prepare a water stop having a skin disease treatment and preventive effect comprising a primary extract extracted with at least one solvent selected from propylene glycol, acetonitrile, acetone (acetone) as an active ingredient, More preferably, the primary extract is extracted as one or more solvents selected from dichloromethane (dichloromethane), chloroform (CHCl3), hexane (hexane), ether (ether) to include a secondary extract purified as an active ingredient. To provide a water stop and disposable absorbent products.

In addition, the disposable absorbent product refers to a product that absorbs body fluids excreted by various physiological actions, that is, a product that receives urine and feces secretions, menstrual secretions and vaginal secretions. Specifically, it refers to disposable diapers used by infants or adults, menstrual products such as sanitary napkins and vaginal inlets, urinary incontinence inserts and pantyliners, all used as disposable absorbent products. It is preferable that it is applicable to a product and is not limited to what was enumerated above.

The extract of the polygonum tinctorium and the yellow lacquer tree (Dendropanax morbifera) of the present invention can be prepared by the following method.

First, as shown in Figure 1, the material preparation step of preparing at least one of the side and hwangchil wood as a material; A grinding step of grinding the prepared material; A first extraction step of obtaining a first extract by adding a first extraction solvent to the pulverized product pulverized through a crushing step; A second extraction step of suspending the primary extract as a crude extract in water and then adding a second extraction solvent to obtain a secondary extract; An extract impregnation step of impregnating a primary extract or a secondary extract with a cloth or a nonwoven fabric used in a water stop or a disposable absorbent product; And it comprises a product packaging step of packaging by drying and sterilizing the water and disposable absorbent products according to the intended use.

In the material preparation step and the grinding step, bark or leaves and seeds of polygonum tinctorium and dendropanax morbifera are prepared, washed, dried and ground.

After pulverization, the first extraction solvent was added, the mixture was cooled to 72 hours at room temperature, filtered, and the filtered extract solution was concentrated to obtain a primary extract.

At this time, the first extraction solvent that can be used is a group consisting of purified water, methanol, ethanol, propanol, butanol, methyl ethyl ketone, glycerol, ethylene glycol, propylene glycol, acetonitrile, 1,3-butylene glycol, ethyl acetate and acetone At least one solvent selected from among them is used.

The primary extract obtained here is suspended as a crude extract in water, and then the primary extract is extracted and purified with one or more solvents selected from a second extraction solvent, dichloromethane, chloroform, hexane and ether, to obtain a secondary extract. have.

Thereafter, the primary extract or the secondary extract is sprayed onto a wet tissue or a disposable absorbent product in a spray spray method, or the primary extract or the secondary extract is impregnated with a cloth or a nonwoven fabric used for a wet tissue or a disposable absorbent product.

At the time of impregnation, it is preferable to simultaneously perform chemical activation while treating the primary extract or secondary extract by flowing a microcurrent of 0.06 mA _to 1 mA for 3 to 10 minutes.

Most preferably, the product is packaged by sterilization after treatment for 4 to 5 minutes.

Hereinafter, the present invention will be described in more detail.

After drying and crushing 2kg of polygonum tinctorium leaf, 4L of ethanol (EtOH) was added, and the resultant was filtered for 72 hours at room temperature. The filtered extract was concentrated to obtain 46g of the primary extract. The primary extract obtained here was suspended as water as a crude extract, and the primary extract was extracted with 500 ml of hexane and purified to obtain 6 g of the secondary extract.

After crushing 400 g of bark or leaves and seeds of the yellow lacquer tree (Dendropanax morbifera), 4 L of ethanol (EtOH) was added, and the mixture was wetted at room temperature for 72 hours, filtered, and the filtered extract was concentrated to obtain 41 g of the primary extract. The primary extract obtained here was suspended as water as a crude extract, and the primary extract was extracted with 500 ml of hexane and purified to obtain 5 g of the secondary extract.

At the time of impregnation, a microcurrent of 0.3 mA was flowed for 4 minutes as a secondary extract.

After extracting the extract obtained in the [Example 1] and [Example 2] of the present invention through a multi-stage filtration process to obtain a filtrate, the mixture was left for 7 days at a temperature of 3 ℃ and the supernatant except the precipitate was again filtered in a multi-stage , By spraying the nonwoven fabric cut to a certain size or by immersing the nonwoven fabric in the mixture of the extract and then compressed so that the mixture is impregnated in the nonwoven fabric.

Thereafter, sterile packaging to prepare a disposable absorbent product of the present invention.

Experimental Example 1: Evaluation of Skin Safety

Meanwhile, the extracts obtained in Examples 1 and 2 were subjected to a closed patch test for 50 healthy men and women in their 20s and 30s for 20 days in order to evaluate skin stability according to long-term use. The tops of both arms of the subject were washed with 70% isopropyl alcohol aqueous solution, and the composition of the present invention was clogged with this solution according to a known method.

At this time, the amount of patch was 25 microliters per unit area (cm2), and after 24 hours, the skin of the test site was observed, and the same patch was repeated 10 times with the same material in the same way as the first day of the next day. As a result, almost no skin change was found.

Experimental Example 2: Evaluation of Skin Safety

1) At least 99.9% of staphylococcus and pneumococcal sterilization, and the antibacterial fiber to which the extract obtained in Example 1 and Example 2 was given was washed 10 times after inoculating Staphylococcus aureus and pneumococci, and the removal rate of the bacteria was examined as follows. As shown in [1], the average reduction rate was about 90%.

Test Sample Germ removal rate (%) 10 times after washing Staphylococcus Pneumococcus over 90 over 90

2) The extracts obtained in Examples 1 and 2 were cut to a size of 1.5 cm × 1.5 cm from water tissues of 50 healthy adults and attached to the skin, and the skin change after 24 hours was measured. This resulted in that the extracts of the prunus chinensis and do not irritate the skin.

3) The extracts obtained in Examples 1 and 2 were divided into the experimental control group, which was subjected to the general control group, and the non-woven fabric to the general impregnation process and the impregnation process where the microcurrent was flowed, and then dried to determine the adsorption rate of ammonia through KS M0062. According to the standard, the detection was carried out by a detection gas measurement method.

50 ppm ammonia gas was injected into a 5 L container into a 20 cm nonwoven fabric, and the concentration change of the ammonia gas was examined at the time points of 30 minutes, 60 minutes, 90 minutes, and 120 minutes.

Time (minutes) Control group General Impregnation Nonwovens Microcurrent-treated Nonwoven Fabric 0 50 ppm 50 ppm 50 ppm 30 50 ppm 24 ppm 23 ppm 60 49 ppm 21 ppm 17 ppm 90 49 ppm 18 ppm 15 ppm 120 48 ppm 17 ppm 12 ppm

[Table 2] shows the adsorption rate of ammonia between the nonwoven fabric impregnated with polygonum tinctorium and the extract of Dendropanax morbifera and the nonwoven fabric subjected to microcurrent treatment during the impregnation process.

According to the results of [Table 2], the non-woven fabric coated with the extracts of the prunus and the Hwangchil-tree showed a good effect on the ammonia adsorption rate compared to the control group. Indicated.

Moreover, according to the said measurement result, it turned out that the absorbent which was impregnated with the extract of the side of this invention and the yellow lacquer tree has the outstanding ammonia adsorption rate.

According to the above experimental example, the main components are used for the purpose of moisturizing the psoriasis skin (infant, adult atopic dermatitis, psoriasis, senile pruritus) by providing the antibacterial activity to the skin of the human body and adsorption of ammonia gas in the human body. It can be confirmed indirectly that the therapeutic agent has an effect of improving dermatitis.

S100: material preparation step S200: grinding step
S300: 1st extraction step S400: 2nd extraction step
S500: Extract impregnation step S600: Product packaging step

Claims

Wipes and disposable absorbent products comprising the extract of at least one of the side and the Hwangchil wood as an active ingredient.

According to claim 1, In the case of a mixed extract containing both the side and the hwangchil wood,
Wet tissue and disposable absorbent products comprising the extract of the side and the Hwangchil wood as an active ingredient, characterized in that it comprises an extract extracted by mixing any one of the side and the Hwangchil wood in 10 to 70% by weight compared to the other.

Material preparation step of preparing at least one of the side and hwangchil wood material;
A grinding step of grinding the prepared material;
A first extraction step of obtaining a first extract by adding a first extraction solvent to the pulverized product pulverized through the crushing step;
A second extraction step of suspending the primary extract as a crude extract in water and then adding a second extraction solvent to obtain a secondary extract;
An extract impregnation step of impregnating the primary extract or the secondary extract with a cloth or a nonwoven fabric used in a water stop or a disposable absorbent product; And
Method for producing a wet tissue and disposable absorbent products comprising the water and the extract containing the product packaging step to dry and sterilize the disposable product to suit the purpose of use as an active ingredient.

The method of claim 3, wherein the first extraction solvent,
At least one solvent selected from the group consisting of purified water, methanol, ethanol, propanol, butanol, methyl ethyl ketone, glycerol, ethylene glycol, propylene glycol, acetonitrile, 1,3-butylene glycol, ethyl acetate and acetone Method of producing a wet wipes and disposable absorbent products comprising as an active ingredient the side and hwangchil wood extract.

The method of claim 3, wherein the second extraction solvent,
Method for producing a wet wipes and disposable absorbent products comprising the extract of Hwangchil-kuk as an active ingredient, characterized in that at least one solvent selected from dichloromethane, chloroform, hexane, ether.

The method according to any one of claims 3 to 5, wherein in the extract impregnation step,
Method of producing a wet tissue and disposable absorbent product comprising the side and the hwangchil wood extract as an active ingredient, characterized in that to flow a fine current of 0.06 ㎃ ~ 1 동안 for 3 to 10 minutes to the second extract.