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KR20010007724A - The band with an anesthesia effect and sterilization - Google Patents

The band with an anesthesia effect and sterilization Download PDF

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Publication number
KR20010007724A
KR20010007724A KR1020000038064A KR20000038064A KR20010007724A KR 20010007724 A KR20010007724 A KR 20010007724A KR 1020000038064 A KR1020000038064 A KR 1020000038064A KR 20000038064 A KR20000038064 A KR 20000038064A KR 20010007724 A KR20010007724 A KR 20010007724A
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KR
South Korea
Prior art keywords
gauze
band
effect
pharmaceutical
zinc oxide
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Application number
KR1020000038064A
Other languages
Korean (ko)
Inventor
박학수
이채관
강성구
Original Assignee
임준기
주식회사 바이오켐텍
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Application filed by 임준기, 주식회사 바이오켐텍 filed Critical 임준기
Priority to KR1020000038064A priority Critical patent/KR20010007724A/en
Publication of KR20010007724A publication Critical patent/KR20010007724A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/023Adhesive bandages or dressings wound covering film layers without a fluid retention layer
    • A61F13/0243Adhesive bandages or dressings wound covering film layers without a fluid retention layer characterised by the properties of the skin contacting layer, e.g. air-vapor permeability
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PURPOSE: An anesthesia and disinfection plaster is provided, which has wound healing and pain relieving effect without administering other ointment and anodyne for curing a light lacerating, gash and a first degree burn. CONSTITUTION: Hygroscopic adhesive agent of colorlessly transparent is coated on gauze, and a mixture of 0.4mg of acrinol, 300mg of ethyl aminobenzoate, 50mg of lidocaine hydrochloride, and 500mg of zinc oxide is attached to the 10X10cm gauze. So, these gauze attached on the plaster has the advantage of easy wound-curing.

Description

마취효과와 살균력을 가진 밴드{The band with an anesthesia effect and sterilization}The band with an anesthesia effect and sterilization

본 발명은 마취효과와 살균력을 가진 밴드에 관한 것으로, 특히 가벼운 열상, 창상, 1도 화상 등에 별도의 연고제나 진통제의 투여 없이도 상처치유와 진통억제효과를 얻을 수 있도록 한 것이다.The present invention relates to a band having an anesthetic effect and bactericidal power, and in particular, it is possible to obtain a wound healing and analgesic inhibitory effect without the administration of a separate ointment or analgesic agent for light laceration, wound, first degree burn, and the like.

종래의 일회용 밴드는 주로 살균제만이 첨가되어 있어서 특별한 진통효과를 기대할 수 없었다.Conventional disposable bands are mainly added only fungicides could not expect a particular analgesic effect.

특히 가벼운 피부상처에도 소아 등은 심한 통증을 호소할 수 있었다.In particular, even minor skin wounds could complain of severe pain.

본 발명은 이와 같은 종래의 문제점을 해결하기 위한 것으로, 본 발명의 목적은 별도의 연고제나 진통제의 투여 없이 상처치유와 진통억제효과를 얻을 수 있도록 한 마취효과와 살균력을 가진 밴드를 제공하는데 있다.The present invention is to solve such a conventional problem, it is an object of the present invention to provide a band having an anesthetic effect and bactericidal power to obtain a wound healing and analgesic inhibitory effect without the administration of a separate ointment or analgesic.

이하, 첨부된 도면을 참조하여 본 발명의 실시 예를 상세히 설명하도록 한다.Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

본 발명은 거즈에 무색투명의 흡수성이 있는 점착성 물질을 도포한 후 그위에 10×10cm당 아크리놀(약전) 4.0mg, 아미노안식향산에칠(약전) 300mg, 염산리도카인(약전) 50mg, 산화아연(약전) 500mg을 혼합하여 만든 산제를 가한 거즈를 부착시킨 것이다.The present invention is coated with a colorless and transparent absorbent adhesive material on the gauze and then on top of that 4.0 mg of acriol (pharmaceutical), 300 mg of aminobenzoic acid (pharmaceutical) 300 mg, 50 mg of lidocaine (pharmaceutical), zinc oxide per 10 x 10 cm (Pharmacopoeia) 500mg mixed powdered gauze is attached.

본 발명에 함유된 아크리놀은 각종 화농균, 특히 연쇄구균, 포도구균, 임균 등에 대하여 정균 및 살균작용이 있으며, 작용기전은 생체내에서 아크리디늄 이온으로 되어 있어 세포의 호흡효소를 저해하는 것으로 알려져 있다.Acrinol contained in the present invention has bacteriostatic and bactericidal action against various purulent bacteria, especially streptococci, staphylococci, and gonococci, and the mechanism of action is that acridinium ions in vivo inhibit the cellular respiratory enzymes. Known.

생체조직에 거의 자극을 주지 않으며 혈청 단백의 존재하에서도 살균력은 저하하지 않는다고 한다.It hardly irritates biological tissues and does not reduce bactericidal power even in the presence of serum proteins.

산화아연은 피부의 단백질과 결합하여 피막을 형성하고 병변의 수렴, 소염, 보호 및 부드러운 방부작용이 나타낸다.Zinc oxide combines with the proteins of the skin to form a coating, which shows the convergence, anti-inflammatory, protection and gentle preservation of the lesion.

또한, 침출액의 흡수 및 분비억제로 창면과 궤양면을 건조시킨다고 한다. 또한 피부의 염증을 없애고 유아형성, 표피형성을 촉진시켜 피부질환을 개선한다고 한다.In addition, it is said that the window surface and the ulcer surface are dried by the absorption and secretion of the leachate. In addition, it is said to improve skin diseases by eliminating inflammation of the skin and promoting infant formation and epidermal formation.

아미노산 안식향산에칠은 신경말단부에 작용해서 표피박리부의 지각신경을 마비시켜 동통을 신속하게 해소시키는 기능이 있다.The amino acid benzoic acid acts on the nerve endings and paralyzes the perceptual nerves of the epidermal detachment, thereby relieving pain.

또한, 아미노안시향산에칠과 리도카인과 같은 국소마취제는 통증을 조절할 뿐만 아니라 투여부위의 혈류를 증가시키며 손상된 조직의 염증을 감소시키고 바이루스 및 세균의 성장을 억제하는 기능도 있다.In addition, topical anesthetics such as aminoansi-acidic acid and lidocaine not only control pain, but also increase blood flow at the site of administration, reduce inflammation of damaged tissues, and inhibit the growth of viruses and bacteria.

본 발명의 상기의 기능으로 인해 다른 연고제, 진통제 등의 투여없이도 간편하게 상처 관리를 할 수 있다.Due to the above functions of the present invention, the wound can be easily managed without administration of other ointments, painkillers, and the like.

본 발명의 실시예와 비교예를 통하여 이를 상세히 설명하면 아래와 같다.Hereinafter, the present invention will be described in detail with reference to Examples and Comparative Examples.

(실시예)(Example)

아래의 표 1과 같이 국소마취제의 함량에 따라 3가지 조성물의 제품을 제조하였다.As shown in Table 1 below, the product of three compositions was prepared according to the amount of local anesthetic.

(표 1)Table 1

구분division 제 품 1Product 1 제 품 2Product 2 제 품 3Product 3 조성물(거즈 10×10cm당)Composition (per gauze 10 × 10 cm) 아크리놀 4.0mg산화아연 500mg염산리도카인 50mgAcrinol 4.0 mg Zinc oxide 500 mg Lidocaine 50 mg 아크리놀 4.0mg산화아연 500mg염산리도카인 50mg아미노안식향산에칠 300mgAcrinol 4.0 mg Zinc oxide 500 mg Lidocaine 50 mg Amino benzoic acid 300 mg 아크리놀 4.0mg산화아연 500mg아미노안식향산에칠 300mgAcrinol 4.0 mg Zinc oxide 500 mg Amino benzoic acid 300 mg

상기 표 1과 같은 실시예에 준하여 제조한 국소마취제가 함유된 밴드의 효과에 대한 비교시험과 평가를 구체적으로 설명한다.Comparative test and evaluation of the effect of the band containing the local anesthetic agent prepared according to the Example as shown in Table 1 will be described in detail.

(시험방법)(Test Methods)

비교시험과 평가는 대상은 가벼운 열상, 창상, 1도 화상 등의 상처를 입은 환자였다. 기존의 소독약만이 주성분인 밴드를 사용한 경험이 있는 7세이상의 환자들 중 30명씩 상기 3가지 제품을 사용하게 한후 결과를 비교 평가 하였다. 환자의 선입견을 배제하기 위해 각제품의 성분에 대해 실험전에 설명해 주지 않았다.Comparative trials and evaluations included patients with minor lacerations, wounds, and first-degree burns. Thirty of the patients over 7 years of age who had experience using only the antiseptics as the main ingredient were asked to use the three products, and the results were compared. The components of each product were not explained before the experiment to rule out preconceptions.

평가항목을 진통효과의 신속성, 진통력(효과), 진통시간(약효의 지속성), 부작용, 상처의 치유 및 보호 효과, 재사용 여부 등 모두 6개항목으로 하여 비교평가 하였다.The evaluation items were compared and evaluated by six items including promptness of analgesic effect, analgesic force (effect), analgesic time (continuity of drug), side effects, wound healing and protection effect, and reuse.

구체적인 평가사항은 다음과 같다.Specific evaluation items are as follows.

1. 진통효과의 신속성은 어떠한가 ?What is the rapidity of the analgesic effect?

① 효과가 없다 ② 1∼2시간 ③ 30분∼1시간 ④ 10∼30분 ⑤ 10분이내① No effect ② 1 to 2 hours ③ 30 minutes to 1 hour ④ 10 to 30 minutes ⑤ Within 10 minutes

2. 진통효과가 있는가 ?2. Is there an analgesic effect?

① 통증이 매우 심해 참을 수 없다 ② 약간 통증을 느꼈다 ③ 모르겠다 ④ 거의 통증을 느끼지 못했다 ⑤ 전혀 통증을 느끼지 못했다① The pain is so severe that I can't stand it ② I felt some pain ③ I don't know ④ I hardly felt any pain ⑤ I didn't feel any pain at all

3. 진통효과의 지속성(약효의 지속성)은 어떠한가 ?3. What is the persistence of analgesic effects?

① 30분 이내 ② 30분∼1시간 ③ 1∼2시간 ④ 2∼4시간 ⑤ 4시간 이상① Within 30 minutes ② 30 minutes to 1 hour ③ 1 to 2 hours ④ 2 to 4 hours ⑤ 4 hours or more

4. 사용후 부작용(화끈거림, 따가움, 가려움 등)은 어떠한가 ?4. What are the side effects after use (burning, itching, itching, etc.)?

① 매우 심해 참을 수 없다 ② 참을만 했다 ③ 약간 있다 ④ 거의 없다 ⑤ 전혀 없다① Very hard to bear ② Tolerable ③ Somewhat ④ Almost no ⑤ No at all

5. 기존 밴드에 비해 상처의 보호 및 치유효과에 대해 만족하는가 ?5. Are you satisfied with the wound's protection and healing effects compared to existing bands?

① 매우 불만족스럽다 ② 덜 효과적이라 생각한다 ③ 모르겠다 ④ 대체적으로 만족한다 ⑤ 매우 만족한다① Very dissatisfied ② Think less effective ③ Don't know ④ Almost satisfied ⑤ Very satisfied

6. 재사용 여부 ?6. Whether to reuse?

① 다시는 사용하지 않겠다 ② 별로 사용하고 싶은 생각이 없다 ③ 모르겠다 ④ 사용할 만하다고 생각한다 ⑤ 꼭 사용하겠다① I will not use it again ② I don't want to use it very much ③ I don't know ④ I think it's worth using ⑤ I will use it

상기 항목에 대한 평가점수는 각 평가항에 대한 효과를 기준(평가점수)으로 환자 30명의 평균값을 나타내었다.Evaluation scores for the above items represent the average value of 30 patients based on the effect of each evaluation term (the evaluation score).

(평가점수)(Score)

5점 - (각항의⑤), 4점 - (각항의④), 3점 - (각항의③), 2점 - (각항의②) , 1점 - (각항의①)5 points-(⑤ of each term), 4 points-(④ of each term), 3 points-(③ of each term), 2 points-(② of each term), 1 point-(① of each term)

평가점수 평균값에 대하여, 가: 4.1 - 5.0, 나: 3.5 - 4.0, 다: 2.5 - 3.4,라: 2.4 - 1.0For average scores, a: 4.1-5.0, b: 3.5-4.0, c: 2.5-3.4, d: 2.4-1.0

평가결과는 표 2와 같다.The evaluation results are shown in Table 2.

(표2)제품 1, 2, 3의 각항에 대한 평가(Table 2) Evaluation of each item of Product 1, 2, 3

설문항 1Question 1 설문항 2Question 2 설문항 3Question 3 설문항 4Question 4 설문항 5Question 5 설문항 6Question 6 제 품 1Product 1 All All All I end end 제 품 2Product 2 end end end I end I 제 품 3Product 3 I I end I I end

이상에서 설명한 바와 같은 본 발명은 일차봉합술 등 다른 특별한 시술이 필요하지 않은 열상, 창상, 1도 화상 등의 피부상처를 입은 환자들의 경우에 다른 진통제나 연고제의 투여없이도 간편하게 상처를 보호 및 치료할 수 있도록 하여 상처치유와 진통억제의 효과가 있다.As described above, the present invention can be easily protected and treated without administration of other painkillers or ointments in the case of patients with cutaneous wounds, wounds, and first-degree burns that do not require other special procedures such as primary sutures. Wound healing and pain control is effective.

Claims (1)

거즈에 무색투명의 흡수성이 있는 점착성 물질을 도포한 후 그 위에 10×10cm당 아크리놀(약전) 4.0mg, 아미노안식향산에칠(약전) 300mg, 염산리도카인(약전) 50mg, 산화아연(약전) 500mg을 혼합하여 만든 산제를 가한 마취효과와 살균력을 가진 밴드.After applying the colorless and transparent absorbent adhesive substance to the gauze, 4.0 mg of acrinole (pharmaceutical), 300 mg of aminobenzoic acid (pharmaceutical), 50 mg of lidocaine (pharmaceutical), zinc oxide (pharmaceutical) per 10 × 10 cm A band with anesthetic effect and bactericidal power with powder made by mixing 500mg.
KR1020000038064A 2000-07-04 2000-07-04 The band with an anesthesia effect and sterilization KR20010007724A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111150738A (en) * 2020-02-06 2020-05-15 西安交通大学医学院第二附属医院 External medicine for treating skin diseases

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR880003941Y1 (en) * 1981-12-09 1988-11-09 니혼 소오기 세이야꾸 가부시기가이샤 First aid adhesive tape
KR910009993A (en) * 1988-11-30 1991-06-28 앙리 보크, 자끄 호프 Zig-zag sewing machine and its assembly method
KR0156679B1 (en) * 1996-06-01 1998-12-15 김승호 Bandage
KR19990087178A (en) * 1996-02-23 1999-12-15 기누꼬 오꾸 External preparation for the treatment of lesion tissue
KR20000012701A (en) * 1999-12-20 2000-03-06 조창수 Adhesive Bandage
KR20000017706A (en) * 1999-07-08 2000-04-06 이승하 New pharmaceutical composition of gel preparation containing local anaesthetic agents

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR880003941Y1 (en) * 1981-12-09 1988-11-09 니혼 소오기 세이야꾸 가부시기가이샤 First aid adhesive tape
KR910009993A (en) * 1988-11-30 1991-06-28 앙리 보크, 자끄 호프 Zig-zag sewing machine and its assembly method
KR19990087178A (en) * 1996-02-23 1999-12-15 기누꼬 오꾸 External preparation for the treatment of lesion tissue
KR0156679B1 (en) * 1996-06-01 1998-12-15 김승호 Bandage
KR20000017706A (en) * 1999-07-08 2000-04-06 이승하 New pharmaceutical composition of gel preparation containing local anaesthetic agents
KR20000012701A (en) * 1999-12-20 2000-03-06 조창수 Adhesive Bandage

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111150738A (en) * 2020-02-06 2020-05-15 西安交通大学医学院第二附属医院 External medicine for treating skin diseases

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