KR102481717B1 - 알레르기 예방용 패치 - Google Patents
알레르기 예방용 패치 Download PDFInfo
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- KR102481717B1 KR102481717B1 KR1020200155089A KR20200155089A KR102481717B1 KR 102481717 B1 KR102481717 B1 KR 102481717B1 KR 1020200155089 A KR1020200155089 A KR 1020200155089A KR 20200155089 A KR20200155089 A KR 20200155089A KR 102481717 B1 KR102481717 B1 KR 102481717B1
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- patch
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- allergy
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- 206010020751 Hypersensitivity Diseases 0.000 title claims abstract description 32
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- 208000026935 allergic disease Diseases 0.000 title claims abstract description 23
- 239000000739 antihistaminic agent Substances 0.000 claims abstract description 25
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
또한, 본 발명에 따르면, 일반적으로 알레르기로 인한 부작용을 치료하기 위해 항히스타민제와 함께 스테로이드도 사용하나, 본 발명의 패치는 스테로이드를 포함하지 않아 통풍이 있는 경우에도 사용가능한 장점이 있다.
Description
20: 코팅층
21: 미세침
30: 이형필름
Claims (8)
- 고분자 필름, 및 천연 섬유 또는 고분자 섬유로 이루어진 시트 중 어느 하나 이상을 포함하는 것으로서, 코팅층과의 결합력 향상을 위해 플라즈마를 이용한 표면처리하여 극성이 부여된 기재;
기재의 적어도 일면에 형성되는 항히스타민제를 포함하는 코팅층; 을 포함하며,
상기 고분자 필름은 폴리에틸렌, 폴리프로필렌, 폴리염화비닐, 폴리우레탄 중 어느 하나 이상을 포함하고,
상기 천연 섬유는 셀룰로오스, 키틴, 키토산, 전분, 콜라겐 및 젤라틴 중 어느 하나 이상을 포함하고,
상기 고분자 섬유는 폴리비닐알코올, 폴리글리콜산, 폴리락트산 및 폴리카프로락톤 중 어느 하나 이상을 포함하고,
상기 코팅층은 항히스타민제를 포함하는 조성물을 코팅하여 형성하되, 항히스타민제를 1 중량% 내지 50중량%로 포함하며,
상기 항히스타민제는 클로르페니라민(chlorpheniramine), 트리프롤리딘(triprolidine), 피프린히드리네이트(piprinhydrinate), 히드록시진(hydroxyzine), 메퀴타진(mequitazine), 디펜히드라민(diphenhydramine), 디멘히드리네이트(dimenhydrinate), 메클리진(meclizine), 세티리진(cetirizine), 로라타딘(loratadine), 레보세티리진(levocetirizine), 에바스틴(ebastine), 케토티펜(ketotifen), 펙소페나딘(fexofenadine), 아젤라스틴(azelastine), 데스로라타딘(desloratadine), 베포타스틴(bepotastine), 올로파타딘(olopatadine), 에메다스틴(emedastine), 에피나스틴(epinastine) 및 레보카바스틴(levocabastine) 어느 하나 이상을 포함하는 알레르기 예방용 패치. - 제1항에 있어서,
상기 코팅층은 하이드로겔 성분을 더 포함하는 알레르기 예방용 패치. - 제1항에 있어서,
상기 코팅층의 기재가 형성된 면의 반대면은 이형필름을 포함하는 알레르기 예방용 패치. - 삭제
- 삭제
- 제1항에 있어서,
상기 코팅층은 화산석분말, 굴패각분말 중에서 적어도 1종의 항균성재료를 더 포함하는 알레르기 예방용 패치. - 제1항에 있어서,
상기 코팅층의 일면은 미세침 형상인 것을 특징으로 하는 알레르기 예방용 패치. - 제1항에 있어서,
상기 알레르기 예방용 패치는 조영제 부작용 예방용 또는 음식물 섭취로 인한 알레르기 예방용인 것을 특징으로 하는 알레르기 예방용 패치.
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